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Des Moines

$304+ Cheap flights from Portland, ME to Des Moines (PWM - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — DSM
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Portland to Des Moines

Cheapest flights from Portland to Des Moines
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/245:00 pmPWM - DSM
1 stop5h 32mUnited Airlines
Tue 12/23:17 pmDSM - PWM
1 stop5h 00mUnited Airlines
Deal found 10/28$304
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:46 amPWM - DSM
1 stop7h 37mAmerican Airlines
Sun 12/144:07 pmDSM - PWM
1 stop5h 27mAmerican Airlines
Deal found 10/26$367
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:00 amPWM - DSM
2 stops9h 20mUnited Airlines
Sun 12/148:00 amDSM - PWM
1 stop5h 22mUnited Airlines
Deal found 10/26$394
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:21 pmPWM - DSM
1 stop7h 34mAmerican Airlines
Tue 12/23:18 pmDSM - PWM
1 stop5h 17mAmerican Airlines
Deal found 10/28$398
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/259:45 amPWM - DSM
1 stop5h 34mUnited Airlines
Wed 12/33:17 pmDSM - PWM
2 stops6h 52mUnited Airlines
Deal found 10/27$404
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/259:45 amPWM - DSM
1 stop5h 34mUnited Airlines
Tue 12/23:17 pmDSM - PWM
2 stops6h 52mUnited Airlines
Deal found 10/27$407

Cheap flight deals from Portland to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$304
(United Airlines)

Popular in

December

Cheapest in

August

Average price

$446
Provider with most accurate pricing for Portland-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Des Moines flights.
Search Deals
From Portland to Des Moines
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($53 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.

Fly from

Portland

Fly to

Des Moines

Route

Depart

Return

Price

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Mon 11/24

5:21 pm-11:55 pm

1 stop7h 34m

Des Moines

Tue 12/2

6:00 am-11:46 am

1 stop4h 46m

$304

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Mon 11/24

5:00 pm-9:32 pm

1 stop5h 32m

Des Moines

Tue 12/2

3:17 pm-9:17 pm

1 stop5h 00m

$304

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Mon 12/8

5:46 am-12:23 pm

1 stop7h 37m

Des Moines

Sun 12/14

4:07 pm-10:34 pm

1 stop5h 27m

$367

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Mon 12/8

6:00 am-2:20 pm

2 stops9h 20m

Des Moines

Sun 12/14

8:00 am-2:22 pm

1 stop5h 22m

$394

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 11/25

5:21 pm-11:55 pm

1 stop7h 34m

Des Moines

Tue 12/2

3:18 pm-9:35 pm

1 stop5h 17m

$398

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 11/25

9:45 am-2:19 pm

1 stop5h 34m

Des Moines

Wed 12/3

3:17 pm-11:09 pm

2 stops6h 52m

$404

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 3/31

4:50 pm-8:53 pm

1 stop5h 03m

Des Moines

Wed 4/1

6:20 am-11:57 am

1 stop4h 37m

$407

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 11/25

9:45 am-2:19 pm

1 stop5h 34m

Des Moines

Tue 12/2

3:17 pm-11:09 pm

2 stops6h 52m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Compare providers for flights from Portland to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland, Maine-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland, Maine-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland, Maine-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Des Moines

What is the cheapest month to book a flight from Portland, Maine to Des Moines?

Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Des Moines (average of $101). Flying from Portland, Maine to Des Moines in February is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to DSM?

Find hourly flight availability from Portland to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

One of the essential ways to save on airfare from Portland, Maine to Des Moines is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 72% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 28, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Portland to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Crew

8.5

Boarding

8.2

Overall

7.9

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Crew

8.5

Boarding

8.2

Overall

7.9

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
9,001 reviews
Delta
7.9
Good
7,994 reviews

Crew

8.5

Boarding

8.2

Overall

7.9

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Crew

8.5

Boarding

8.2

Overall

7.9

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Des Moines?

    For as low as $304, American Airlines can have you in Des Moines from Portland, Maine in 5h 32m. Airlines will cover a distance of 1192 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Portland, Maine to Des Moines round-trip?

    According to our current data, Delta ($229), American Airlines ($249), and United Airlines ($328) offers the cheapest pricing from Portland, Maine to Des Moines. You may be able to fly from Portland, Maine to Des Moines for 47% less than the average price by searching for these airlines.

  • Can I find deals for flights from Portland to Des Moines that include hotel bookings?

    Yes. In addition to deals on Portland to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Des Moines.

  • Can I find deals for business class flights from Portland to Des Moines?

    Yes. Cheapflights offers flight deals from Portland to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Des Moines?

    Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Des Moines (average of $101). Flying from Portland, Maine to Des Moines in February is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top 3 airlines flying from Portland to Des Moines

Discover the top 3 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$229Average$369FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$249Average$407FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$328Average$446FlexibilityNo cancel feeOn-time69%

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