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Des Moines

$186+ Cheap flights from Portland, ME to Des Moines (PWM - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — DSM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Portland to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$229
(American Airlines)

One-way from

$186
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$475
From Portland to Des Moines
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One-way flight from Portland to Des Moines
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Highest demand for flights based on searches. 13% potential increase in price ($67 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Portland to Des Moines

Cheapest flights from Portland to Des Moines
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:43 amPWM - DSM
1 stop7h 41mAmerican Airlines
Sat 11/84:03 pmDSM - PWM
1 stop5h 29mAmerican Airlines
Deal found 9/10$229
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:01 amPWM - DSM
2 stops8h 27mDelta
Sat 11/86:05 amDSM - PWM
1 stop4h 55mDelta
Deal found 9/10$262
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:14 amPWM - DSM
1 stop7h 04mUnited Airlines
Tue 9/303:25 pmDSM - PWM
1 stop5h 19mUnited Airlines
Deal found 9/11$348
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:25 pmPWM - DSM
1 stop17h 07mUnited Airlines
Fri 10/246:36 pmDSM - PWM
1 stop18h 57mUnited Airlines
Deal found 9/10$457
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:00 amPWM - DSM
1 stop7h 19mAmerican Airlines
Thu 10/306:07 amDSM - PWM
1 stop6h 28mAmerican Airlines
Deal found 9/10$497
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:14 amPWM - DSM
1 stop7h 05mUnited Airlines
Mon 9/2911:31 amDSM - PWM
1 stop5h 11mUnited Airlines
Deal found 9/10$547

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.

Fly from

Portland

Fly to

Des Moines

Route

Depart

Return

Price

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 11/5

5:43 am-12:24 pm

1 stop7h 41m

Des Moines

Sat 11/8

4:03 pm-10:32 pm

1 stop5h 29m

$229

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 11/5

6:01 am-1:28 pm

2 stops8h 27m

Des Moines

Sat 11/8

6:05 am-12:00 pm

1 stop4h 55m

$262

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Fri 9/26

6:14 am-12:18 pm

1 stop7h 04m

Des Moines

Tue 9/30

3:25 pm-9:44 pm

1 stop5h 19m

$348

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Sun 10/19

6:25 pm-10:32 am

1 stop17h 07m

Des Moines

Fri 10/24

6:36 pm-2:33 pm

1 stop18h 57m

$457

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 10/22

6:00 am-12:19 pm

1 stop7h 19m

Des Moines

Thu 10/30

6:07 am-1:35 pm

1 stop6h 28m

$497

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Thu 9/25

6:14 am-10:32 am

1 stop5h 18m

Des Moines

Mon 9/29

11:31 am-11:13 pm

2 stops10h 42m

$552

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Fri 10/10

5:21 pm-11:59 pm

1 stop7h 38m

$186

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Fri 10/10

4:57 pm-9:50 pm

1 stop5h 53m

$199

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Fri 9/26

3:56 pm-9:40 pm

1 stop6h 44m

$234

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Fri 9/26

6:00 am-2:23 pm

2 stops9h 23m

$275

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 11 results
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Best time to book a flight from Portland to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Des Moines

What is the cheapest month to book a flight from Portland, Maine to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Des Moines (average of $336). Flying from Portland, Maine to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to DSM?

Find hourly flight availability from Portland to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

One of the essential ways to save on airfare from Portland, Maine to Des Moines is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 25% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Portland to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Des Moines?

    For as low as $348, American Airlines can have you in Des Moines from Portland, Maine in 7h 04m. Airlines will cover a distance of 1192 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Portland, Maine to Des Moines round-trip?

    According to our current data, Delta ($229), American Airlines ($249), and United Airlines ($328) offers the cheapest pricing from Portland, Maine to Des Moines. You may be able to fly from Portland, Maine to Des Moines for 49% less than the average price by searching for these airlines.

  • Can I find deals for flights from Portland to Des Moines that include hotel bookings?

    Yes. In addition to deals on Portland to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Des Moines.

  • Can I find deals for business class flights from Portland to Des Moines?

    Yes. Cheapflights offers flight deals from Portland to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Des Moines (average of $336). Flying from Portland, Maine to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Portland to Des Moines

Discover the top 3 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$229Average$411FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$249Average$459FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$328Average$496FlexibilityNo cancel feeOn-time69%

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