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Des Moines

$279+ Cheap flights from Portland, ME to Des Moines (PWM - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — DSM
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Portland to Des Moines

Cheapest flights from Portland to Des Moines
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amPWM - DSM
1 stop7h 43mDelta
Wed 1/76:24 amDSM - PWM
1 stop4h 44mDelta
Deal found 12/10$381
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amPWM - DSM
1 stop7h 43mDelta
Sat 1/101:03 pmDSM - PWM
1 stop8h 24mDelta
Deal found 12/10$382
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amPWM - DSM
1 stop7h 43mDelta
Thu 1/86:24 amDSM - PWM
1 stop4h 44mDelta
Deal found 12/10$393
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amPWM - DSM
1 stop7h 43mDelta
Sun 1/116:24 amDSM - PWM
1 stop4h 44mDelta
Deal found 12/10$417
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amPWM - DSM
1 stop7h 43mDelta
Mon 1/56:24 amDSM - PWM
1 stop4h 44mDelta
Deal found 12/10$427
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:30 amPWM - DSM
2 stops10h 03mUnited Airlines
Sat 1/105:30 amDSM - PWM
2 stops12h 24mUnited Airlines
Deal found 12/10$472
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amPWM - DSM
1 stop7h 43mDelta
Fri 1/96:24 amDSM - PWM
1 stop4h 44mDelta
Deal found 12/10$477
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:30 amPWM - DSM
2 stops10h 03mUnited Airlines
Thu 1/88:00 amDSM - PWM
2 stops9h 50mUnited Airlines
Deal found 12/10$483

Find flight deals from Portland to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$381
(Delta)

One-way from

$279
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$551
Provider with most accurate pricing for Portland-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Des Moines flights.
Search Deals
From Portland to Des Moines
Search Deals
One-way flight from Portland to Des Moines
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.

Fly from

Portland

Fly to

Des Moines

Route

Depart

Return

Price

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 12/31

5:45 am-12:28 pm

1 stop7h 43m

Des Moines

Wed 1/7

6:24 am-12:08 pm

1 stop4h 44m

$381

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 12/31

5:45 am-12:28 pm

1 stop7h 43m

Des Moines

Tue 1/6

12:04 pm-11:22 pm

2 stops10h 18m

$386

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Thu 1/1

5:30 am-2:33 pm

2 stops10h 03m

Des Moines

Thu 1/8

8:00 am-2:39 pm

1 stop5h 39m

$398

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 1/7

4:10 pm-9:50 pm

1 stop6h 40m

Des Moines

Sat 1/10

7:50 am-2:39 pm

1 stop5h 49m

$416

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 12/17

11:16 am-10:36 pm

2 stops36h 20m

$279

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 12/17

6:08 am-1:31 pm

1 stop8h 23m

$309

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Sun 12/28

5:48 am-12:26 pm

1 stop7h 38m

$444

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Sun 12/28

7:30 pm-9:40 pm

2 stops27h 10m

$513

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Sun 12/28

11:58 am-11:32 pm

3 stops36h 34m

$864

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Compare providers for flights from Portland to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland, Maine-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland, Maine-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland, Maine-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Des Moines

What is the cheapest month to book a flight from Portland, Maine to Des Moines?

Currently, December is the cheapest month in which you can book a flight from Portland, Maine to Des Moines (average of $92). Flying from Portland, Maine to Des Moines in February is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to DSM?

Find hourly flight availability from Portland to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Portland, Maine to Des Moines is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 72% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Portland to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Des Moines?

    For as low as $381, Delta can have you in Des Moines from Portland, Maine in 7h 43m. Airlines will cover a distance of 1192 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Portland, Maine to Des Moines round-trip?

    According to our current data, Delta ($193), American Airlines ($249), and United Airlines ($319) offers the cheapest pricing from Portland, Maine to Des Moines. You may be able to fly from Portland, Maine to Des Moines for 53% less than the average price by searching for these airlines.

  • Can I find deals for flights from Portland to Des Moines that include hotel bookings?

    Yes. In addition to deals on Portland to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Des Moines.

  • Can I find deals for business class flights from Portland to Des Moines?

    Yes. Cheapflights offers flight deals from Portland to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Des Moines?

    Currently, December is the cheapest month in which you can book a flight from Portland, Maine to Des Moines (average of $92). Flying from Portland, Maine to Des Moines in February is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Top 3 airlines flying from Portland to Des Moines

Discover the top 3 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$229Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$249Average$394FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$328Average$446FlexibilityNo cancel feeOn-time69%

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