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Des Moines

$309+ Cheap flights from Portland, ME to Des Moines (PWM - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — DSM
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Portland to Des Moines

Cheapest flights from Portland to Des Moines
Explore the most affordable flight options available from Portland to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:40 pm
PWM
-
DSM
1 stop16h 21m
American Airlines
Sun 3/12:02 pm
DSM
-
PWM
1 stop7h 48m
American Airlines
Deal found 1/24$414
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:07 am
PWM
-
DSM
1 stop7h 41m
American Airlines
Sun 4/195:00 pm
DSM
-
PWM
1 stop5h 10m
American Airlines
Deal found 1/26$464
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:07 pm
PWM
-
DSM
1 stop6h 04m
American Airlines
Sat 2/145:00 am
DSM
-
PWM
1 stop11h 27m
American Airlines
Deal found 1/26$471
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/21:31 pm
PWM
-
DSM
1 stop7h 57m
American Airlines
Wed 8/125:00 am
DSM
-
PWM
1 stop5h 34m
American Airlines
Deal found 1/27$484
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:17 am
PWM
-
DSM
2 stops10h 24m
Delta
Sat 2/141:02 pm
DSM
-
PWM
2 stops10h 16m
Delta
Deal found 1/26$498
This United Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:45 am
PWM
-
DSM
1 stop6h 08m
United Airlines
Sun 3/18:00 am
DSM
-
PWM
2 stops14h 20m
United Airlines
Deal found 1/24$561
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/104:10 pm
PWM
-
DSM
1 stop6h 40m
United Airlines
Sat 2/143:24 pm
DSM
-
PWM
1 stop4h 45m
United Airlines
Deal found 1/26$567
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:45 am
PWM
-
DSM
1 stop5h 40m
Southwest
Wed 8/127:15 am
DSM
-
PWM
2 stops9h 00m
Southwest
Deal found 1/27$579

Find flight deals from Portland to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$414
(American Airlines)

One-way from

$309
(American Airlines)

Popular in

February

Cheapest in

August

Average price

$349
Provider with most accurate pricing for Portland-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Des Moines flights.
Search Deals
From Portland to Des Moines
Search Deals
One-way flight from Portland to Des Moines
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Portland to Des Moines that are best for you.

Fly from

Portland

Fly to

Des Moines

Route

Depart

Return

Price

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Sun 2/22

5:40 pm-9:01 am

1 stop16h 21m

Des Moines

Sun 3/1

2:02 pm-10:50 pm

1 stop7h 48m

$414

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Thu 4/16

7:07 am-1:48 pm

1 stop7h 41m

Des Moines

Sun 4/19

5:00 pm-11:10 pm

1 stop5h 10m

$464

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 2/10

5:07 pm-10:11 pm

1 stop6h 04m

Des Moines

Sat 2/14

5:00 am-5:27 pm

1 stop11h 27m

$471

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 2/10

6:17 am-3:41 pm

2 stops10h 24m

Des Moines

Sat 2/14

1:02 pm-12:18 am

2 stops10h 16m

$498

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Sun 2/22

5:45 am-10:53 am

1 stop6h 08m

Des Moines

Sun 3/1

8:00 am-11:20 pm

2 stops14h 20m

$561

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 2/10

4:10 pm-9:50 pm

1 stop6h 40m

Des Moines

Sat 2/14

3:24 pm-9:09 pm

1 stop4h 45m

$567

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 4/22

7:07 am-11:28 am

1 stop5h 21m

Des Moines

Sun 4/26

2:18 pm-11:10 pm

1 stop7h 52m

$588

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 2/3

12:43 pm-7:34 pm

1 stop7h 51m

$309

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Mon 2/2

5:20 am-12:46 pm

1 stop8h 26m

$309

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 2/4

12:43 pm-7:34 pm

1 stop7h 51m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 13 results
1
2

Compare providers for flights from Portland to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Des Moines in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland, Maine-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Des Moines

What is the cheapest month to book a flight from Portland, Maine to Des Moines?

Currently, December is the cheapest month in which you can book a flight from Portland, Maine to Des Moines (average of $92). Flying from Portland, Maine to Des Moines in February is currently the most expensive (average of $324). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated January 27, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Portland to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,118 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,118 reviews
Delta
7.9
Good
8,118 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,205 reviews
Delta
7.9
Good
8,118 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,118 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Portland to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Des Moines?

    For as low as $414, American Airlines can have you in Des Moines from Portland, Maine in 16h 21m. Airlines will cover a distance of 1192 mi.

  • What are the cheapest airlines flying from Portland, Maine to Des Moines round-trip?

    According to our current data, Delta ($229), American Airlines ($249), and United Airlines ($319) offers the cheapest pricing from Portland, Maine to Des Moines. You may be able to fly from Portland, Maine to Des Moines for 46% less than the average price by searching for these airlines.

  • Can I find deals for flights from Portland to Des Moines that include hotel bookings?

    Yes. In addition to deals on Portland to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Des Moines.

  • Can I find deals for business class flights from Portland to Des Moines?

    Yes. Cheapflights offers flight deals from Portland to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Des Moines?

    Currently, December is the cheapest month in which you can book a flight from Portland, Maine to Des Moines (average of $92). Flying from Portland, Maine to Des Moines in February is currently the most expensive (average of $324). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Top 3 airlines flying from Portland to Des Moines

Discover the top 3 airlines that operate flights from Portland to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$229Average$352FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$249Average$388FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$319Average$446FlexibilityNo cancel feeOn-time69%

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