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Czech Republic

$219+ Cheap flights from South Carolina to the Czech Republic

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PRG
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from South Carolina to Czech Republic

Cheapest flights from South Carolina to Czech Republic
Explore the most affordable flight options available from South Carolina to Czech Republic. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:40 pm
CLT
-
PRG
1 stop15h 25m
Multiple Airlines
Tue 5/126:50 am
PRG
-
CLT
2 stops14h 07m
Multiple Airlines
Deal found 1/27$501
This CrystalTravel deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:40 pm
CLT
-
PRG
1 stop20h 40m
Lufthansa
Wed 5/136:15 am
PRG
-
CLT
1 stop16h 30m
Lufthansa
Deal found 1/28$502
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:40 pm
CLT
-
PRG
1 stop12h 05m
Multiple Airlines
Wed 5/136:10 am
PRG
-
CLT
2 stops20h 47m
Multiple Airlines
Deal found 1/27$503
This CrystalTravel deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:40 pm
CLT
-
PRG
1 stop20h 40m
Lufthansa
Fri 5/86:15 am
PRG
-
CLT
1 stop16h 30m
Lufthansa
Deal found 1/27$505
This CrystalTravel deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:40 pm
CLT
-
PRG
1 stop15h 25m
Lufthansa
Tue 5/126:15 am
PRG
-
CLT
1 stop16h 30m
Lufthansa
Deal found 1/27$506
This AirNGo deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:00 pm
CLT
-
PRG
2 stops18h 05m
Multiple Airlines
Mon 11/24:45 pm
PRG
-
CLT
1 stop30h 10m
Multiple Airlines
Deal found 1/27$507
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:32 pm
CAE
-
PRG
2 stops15h 33m
United Airlines
Wed 3/117:30 am
PRG
-
CAE
2 stops21h 14m
United Airlines
Deal found 1/28$511
This AirNGo deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:00 pm
CLT
-
PRG
2 stops18h 05m
Air Canada
Mon 11/21:45 pm
PRG
-
CLT
2 stops37h 14m
Air Canada
Deal found 1/28$516
This FlightHub deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:40 pm
CLT
-
PRG
1 stop12h 05m
Lufthansa
Thu 5/79:35 am
PRG
-
CLT
1 stop13h 10m
Lufthansa
Deal found 1/27$517
This oojo deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:17 pm
CLT
-
PRG
2 stops15h 28m
British Airways
Wed 5/136:30 am
PRG
-
CLT
2 stops21h 18m
British Airways
Deal found 1/27$518
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:40 pm
CLT
-
PRG
1 stop20h 40m
United Airlines
Fri 5/86:15 am
PRG
-
CLT
1 stop16h 30m
United Airlines
Deal found 1/27$519
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2910:41 am
CAE
-
PRG
2 stops20h 04m
United Airlines
Mon 4/201:25 pm
PRG
-
CAE
2 stops37h 56m
United Airlines
Deal found 1/28$523

Find flight deals from South Carolina to Czech Republic

Keep the following information in mind while searching for South Carolina to Czech Republic flight deals. Data was last updated January 29, 2026.

Round-trip from

$501
(Mytrip)

One-way from

$219
(oojo)
From South Carolina to Czech Republic
Search Deals
One-way flight from South Carolina to Czech Republic
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Czech Republic that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from South Carolina to the Czech Republic that are best for you.

Fly from

South Carolina

Fly to

Czech Republic

Route

Depart

Return

Price

ColumbiaPrague

CAE - PRG

CAEPRG

Columbia Metropolitan

Wed 3/4

3:32 pm-1:05 pm

2 stops15h 33m

Václav Havel Prague

Wed 3/11

7:30 am-11:44 pm

2 stops21h 14m

$511

ColumbiaPrague

CAE - PRG

CAEPRG

Columbia Metropolitan

Wed 4/15

10:41 am-9:20 pm

2 stops28h 39m

Václav Havel Prague

Wed 4/22

6:10 am-9:21 pm

2 stops21h 11m

$511

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 4/29

6:40 pm-12:45 pm

1 stop12h 05m

Václav Havel Prague

Tue 5/12

9:35 am-4:45 pm

1 stop13h 10m

$519

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 4/29

6:40 pm-12:45 pm

1 stop12h 05m

Václav Havel Prague

Wed 5/13

6:15 am-4:45 pm

1 stop16h 30m

$519

ColumbiaPrague

CAE - PRG

CAEPRG

Columbia Metropolitan

Sun 3/29

10:41 am-12:45 pm

2 stops20h 04m

Václav Havel Prague

Mon 4/20

1:25 pm-9:21 pm

2 stops37h 56m

$523

ColumbiaPrague

CAE - PRG

CAEPRG

Columbia Metropolitan

Sat 3/28

7:39 pm-10:00 am

2 stops33h 21m

Václav Havel Prague

Mon 4/20

1:25 pm-10:06 am

2 stops50h 41m

$524

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Tue 4/28

6:40 pm-12:45 pm

1 stop12h 05m

Václav Havel Prague

Mon 5/11

1:25 pm-4:45 pm

1 stop33h 20m

$529

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Mon 4/27

10:34 am-4:05 pm

2 stops23h 31m

Václav Havel Prague

Tue 5/5

6:10 am-6:55 pm

2 stops18h 45m

$532

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Mon 4/27

10:34 am-12:45 pm

2 stops20h 11m

Václav Havel Prague

Wed 5/13

6:10 am-6:55 pm

2 stops18h 45m

$532

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Sun 3/1

7:50 am-1:05 pm

2 stops23h 15m

Václav Havel Prague

Tue 3/17

7:25 am-8:57 pm

2 stops18h 32m

$555

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 48 results
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Best time to book a flight from South Carolina to Czech Republic

Have a flexible travel schedule? Discover the best time to fly to Czech Republic from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Czech Republic

What is the cheapest month to book a flight from South Carolina to Czech Republic?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Czech Republic (average of $506). Flying from South Carolina to Czech Republic in June is currently the most expensive (average of $1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Czech Republic. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Czech Republic?

    For as low as $519, United Airlines can have you in Czech Republic from South Carolina in 12h 05m. Airlines will cover a distance of 4608 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Carolina to Czech Republic that include hotel bookings?

    Yes. In addition to deals on South Carolina to Czech Republic flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Czech Republic?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Czech Republic.

  • Can I find deals for business class flights from South Carolina to Czech Republic?

    Yes. Cheapflights offers flight deals from South Carolina to Czech Republic by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Czech Republic?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Czech Republic (average of $506). Flying from South Carolina to Czech Republic in June is currently the most expensive (average of $1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Czech Republic

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Czech Republic

Discover the top 3 airlines that operate flights from South Carolina to Czech Republic. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$485FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$693Average$906FlexibilityNo cancel feeOn-time69%
DeltaCheapest$735Average$1,104FlexibilityNo cancel feeOn-timeN/A

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