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$656+ Cheap flights from Des Moines (DSM) to the Czech Republic

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PRG
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Cheap flight deals from Des Moines to Czech Republic

Keep the following information in mind while searching for Des Moines to Czech Republic flight deals. Data was last updated November 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$541
(FlightHub)

Popular in

June

Cheapest in

January

Average price

$636
Provider with most accurate pricing for Des Moines-Václav Havel Prague flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Václav Havel Prague flights.
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From Des Moines to Czech Republic
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Highest demand for flights based on searches. 16% potential increase in price ($174 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($68 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Des Moines to Czech Republic

Cheapest flights from Des Moines to Czech Republic
Explore the most affordable flight options available from Des Moines to Czech Republic. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:52 pmDSM - PRG
2 stops48h 33mUnited Airlines
Wed 11/197:30 amPRG - DSM
2 stops20h 15mUnited Airlines
Deal found 11/3$786
This KLM deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:33 pmDSM - PRG
2 stops16h 02mKLM
Thu 12/256:00 amPRG - DSM
2 stops21h 02mKLM
Deal found 11/3$1,461
This Air Canada deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/81:05 pmDSM - PRG
3 stops17h 00mAir Canada
Wed 11/197:30 amPRG - DSM
3 stops21h 02mAir Canada
Deal found 11/3$1,642
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:05 amDSM - PRG
3 stops28h 25mMultiple Airlines
Sat 12/276:00 amPRG - DSM
2 stops24h 51mMultiple Airlines
Deal found 11/2$1,714
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:05 amDSM - PRG
3 stops28h 25mMultiple Airlines
Fri 12/2611:40 amPRG - DSM
2 stops19h 11mMultiple Airlines
Deal found 11/4$1,771
This Ovago deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:46 pmDSM - PRG
2 stops16h 29mLufthansa
Sat 12/271:45 pmPRG - DSM
2 stops14h 55mLufthansa
Deal found 11/2$1,787

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Czech Republic that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Des Moines to the Czech Republic that are best for you.

Fly from

Des Moines

Fly to

Czech Republic

Route

Depart

Return

Price

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 3/27

8:00 am-10:50 am

2 stops20h 50m

Václav Havel Prague

Tue 3/31

6:00 am-5:33 pm

2 stops18h 33m

$656

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 5/1

6:45 pm-4:05 pm

2 stops14h 20m

Václav Havel Prague

Sun 5/10

6:10 am-9:36 pm

2 stops22h 26m

$687

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Sat 4/25

11:30 am-12:45 pm

3 stops18h 15m

Václav Havel Prague

Fri 5/1

9:35 am-9:36 pm

3 stops19h 01m

$1,340

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 12/18

6:33 pm-5:35 pm

2 stops16h 02m

Václav Havel Prague

Thu 12/25

6:00 am-8:02 pm

2 stops21h 02m

$1,461

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 12/19

8:05 am-7:30 pm

3 stops28h 25m

Václav Havel Prague

Sat 12/27

6:00 am-11:51 pm

2 stops24h 51m

$1,714

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 12/19

8:05 am-7:30 pm

3 stops28h 25m

Václav Havel Prague

Fri 12/26

11:40 am-11:51 pm

2 stops19h 11m

$1,771

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 12/18

6:33 pm-5:35 pm

2 stops16h 02m

$1,089

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 12/18

11:35 am-1:55 pm

3 stops19h 20m

$1,626

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Best time to book a flight from Des Moines to Czech Republic

Have a flexible travel schedule? Discover the best time to fly to Czech Republic from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to the Czech Republic
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Czech Republic

Get insights into the airlines that provide service to Czech Republic. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Czech Republic. Reviews last updated November 5, 2025.
Read through reviews of airlines operating flights from Des Moines to the Czech Republic, such as United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,002 reviews

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,002 reviews
United Airlines
7.4
Good
9,002 reviews

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Czech Republic. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Czech Republic?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Czech Republic. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Czech Republic?

    For as low as $687, United Airlines can have you in Czech Republic from Des Moines in 14h 20m. The distance from Des Moines to Czech Republic is about 4753 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Des Moines to Czech Republic that include hotel bookings?

    Yes. In addition to deals on Des Moines to Czech Republic flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Czech Republic?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Czech Republic.

  • Can I find deals for business class flights from Des Moines to Czech Republic?

    Yes. Cheapflights offers flight deals from Des Moines to Czech Republic by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Des Moines to Czech Republic

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Des Moines to Czech Republic

Discover the top airline that operate flights from Des Moines to Czech Republic. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$597Average$903FlexibilityNo cancel feeOn-time69%

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