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$477+ Cheap flights from Des Moines (DSM) to the Czech Republic

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PRG
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Des Moines to Czech Republic

Keep the following information in mind while searching for Des Moines to Czech Republic flight deals. Data was last updated September 17, 2025.

Round-trip from

$550
(LionTravel)

One-way from

$477
(American Airlines)

Popular in

June

Cheapest in

January

Average price

$989
From Des Moines to Czech Republic
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One-way flight from Des Moines to Czech Republic
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Highest demand for flights based on searches. 20% potential increase in price ($236 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($66 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Czech Republic

Cheapest flights from Des Moines to Czech Republic
Explore the most affordable flight options available from Des Moines to Czech Republic. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This LionTravel deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LionTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/302:13 pmDSM - PRG
2 stops37h 32mScandinavian Airlines
Thu 11/67:20 pmPRG - DSM
2 stops34h 10mScandinavian Airlines
Deal found 9/15$550
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/303:48 pmDSM - PRG
2 stops20h 17mAmerican Airlines
Thu 11/66:45 amPRG - DSM
2 stops24h 05mAmerican Airlines
Deal found 9/15$583
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/313:48 pmDSM - PRG
2 stops16h 12mAmerican Airlines
Fri 11/76:00 amPRG - DSM
2 stops24h 50mAmerican Airlines
Deal found 9/16$584
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:31 pmDSM - PRG
2 stops17h 39mAmerican Airlines
Thu 10/237:10 amPRG - DSM
2 stops20h 01mAmerican Airlines
Deal found 9/16$638
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:14 pmDSM - PRG
2 stops39h 01mUnited Airlines
Sat 11/83:10 pmPRG - DSM
2 stops37h 22mUnited Airlines
Deal found 9/17$707
This Air Canada deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/301:05 pmDSM - PRG
3 stops18h 00mAir Canada
Thu 11/67:35 amPRG - DSM
3 stops20h 57mAir Canada
Deal found 9/15$957

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Czech Republic that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Des Moines to the Czech Republic that are best for you.

Fly from

Des Moines

Fly to

Czech Republic

Route

Depart

Return

Price

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 10/30

2:13 pm-9:45 am

2 stops37h 32m

Václav Havel Prague

Thu 11/6

7:20 pm-10:30 pm

2 stops34h 10m

$550

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 10/30

3:48 pm-6:05 pm

2 stops20h 17m

Václav Havel Prague

Thu 11/6

6:45 am-11:50 pm

2 stops24h 05m

$583

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 10/31

3:48 pm-2:00 pm

2 stops16h 12m

Václav Havel Prague

Fri 11/7

6:00 am-11:50 pm

2 stops24h 50m

$584

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 11/28

6:59 pm-4:55 pm

2 stops14h 56m

Václav Havel Prague

Fri 12/5

6:00 am-5:57 pm

2 stops18h 57m

$585

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 10/31

3:48 pm-2:00 pm

2 stops16h 12m

$477

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 10/31

1:05 pm-2:05 pm

3 stops19h 00m

$822

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Des Moines to Czech Republic

Have a flexible travel schedule? Discover the best time to fly to Czech Republic from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to the Czech Republic
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Czech Republic

Get insights into the airlines that provide service to Czech Republic. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Czech Republic. Reviews last updated September 17, 2025.
Read through reviews of airlines operating flights from Des Moines to the Czech Republic, such as United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Boarding

7.7

Food

6.6

Crew

8.1

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Boarding

7.7

Food

6.6

Crew

8.1

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Czech Republic. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Czech Republic?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Czech Republic. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Czech Republic?

    For as low as $583, Scandinavian Airlines can have you in Czech Republic from Des Moines in 20h 17m. The distance from Des Moines to Czech Republic is about 4753 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Des Moines to Czech Republic that include hotel bookings?

    Yes. In addition to deals on Des Moines to Czech Republic flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Czech Republic?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Czech Republic.

  • Can I find deals for business class flights from Des Moines to Czech Republic?

    Yes. Cheapflights offers flight deals from Des Moines to Czech Republic by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Czech Republic?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Czech Republic (average of $651). Flying from Des Moines to Czech Republic in June is currently the most expensive (average of $1,119). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Czech Republic

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Des Moines to Czech Republic

Discover the top airline that operate flights from Des Moines to Czech Republic. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$588Average$903FlexibilityNo cancel feeOn-time69%

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