$69+ Cheap flights from Greenville (GSP) to Columbus
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — CMH
Jul 27 — Aug 31
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Columbus
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Cheapest flights from Greenville to ColumbusExplore the most affordable flight options available from Greenville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.
Explore the most affordable flight options available from Greenville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.
This Breeze Airways deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/284:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Mon 9/76:28 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Mon 8/176:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$137
This Breeze Airways deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:23 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Mon 9/76:28 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/74:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Fri 8/146:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/23![Breeze Airways logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/134:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Fri 7/176:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Mon 7/136:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/26![Breeze Airways logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Mon 7/66:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:32 pm
GSP
- CMH
2 stops21h 01m
Multiple Airlines
Fri 10/166:32 pm
CMH
- GSP
Nonstop1h 20m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:27 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Mon 10/196:32 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$185
Best flights from Greenville to ColumbusDiscover carefully curated flight deals from Greenville to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 27, 2026.
Discover carefully curated flight deals from Greenville to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 27, 2026.
This Breeze Airways deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/124:27 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Fri 10/166:32 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$138
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:00 am
GSP
- CMH
2 stops10h 00m
Southwest
Mon 8/178:05 am
CMH
- GSP
2 stops8h 00m
Southwest
Deal found 6/24![Southwest logo]()
$330
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:15 am
GSP
- CMH
1 stop4h 06m
Delta
Sun 11/18:00 am
CMH
- GSP
1 stop5h 08m
Delta
Deal found 6/26![Delta logo]()
$347
This Breeze Airways deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Mon 7/206:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/27![Breeze Airways logo]()
$178
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:55 pm
GSP
- CMH
1 stop4h 15m
Delta
Sat 1/28:05 am
CMH
- GSP
1 stop5h 03m
Delta
Deal found 6/26![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:15 am
GSP
- CMH
1 stop3h 40m
Southwest
Fri 10/161:10 pm
CMH
- GSP
2 stops8h 15m
Southwest
Deal found 6/25![Southwest logo]()
$352
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:15 am
GSP
- CMH
1 stop6h 13m
Delta
Sun 11/87:00 am
CMH
- GSP
1 stop6h 08m
Delta
Deal found 6/22![Delta logo]()
$347
Last-minute flights from Greenville to ColumbusDiscover last-minute flight deals from Greenville to Columbus. Data last updated June 27, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Columbus. Data last updated June 27, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/294:23 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Fri 7/36:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Mon 7/66:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Mon 7/136:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/26![Breeze Airways logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/134:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Fri 7/176:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$172
This Breeze Airways deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Mon 7/206:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:45 pm
GSP
- CMH
1 stop20h 26m
Multiple Airlines
Mon 7/206:45 pm
CMH
- GSP
Nonstop1h 20m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:45 pm
GSP
- CMH
1 stop20h 26m
Multiple Airlines
Mon 7/276:45 pm
CMH
- GSP
Nonstop1h 20m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:40 pm
GSP
- CMH
1 stop17h 50m
Breeze Airways
Mon 8/36:45 pm
CMH
- GSP
Nonstop1h 20m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$244
One-way flights from Greenville to ColumbusSearch for one-way flight options from Greenville to Columbus. Find affordable one-way fares based on user searches. Data last updated June 27, 2026.
Search for one-way flight options from Greenville to Columbus. Find affordable one-way fares based on user searches. Data last updated June 27, 2026.
This Breeze Airways deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$83
This Breeze Airways deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/74:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Deal found 6/26![Breeze Airways logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$94
This Breeze Airways deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/244:40 pm
GSP
- CMH
Nonstop1h 25m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:45 pm
GSP
- CMH
1 stop13h 23m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/233:43 pm
GSP
- CMH
1 stop18h 00m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$134
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:55 pm
GSP
- CMH
1 stop3h 55m
Southwest
Deal found 6/26![Southwest logo]()
$135
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:52 am
GSP
- CMH
1 stop4h 46m
Delta
Deal found 6/23![Delta logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:45 pm
GSP
- CMH
1 stop13h 23m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$141
Find flight deals from Greenville to Columbus
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 27, 2026.
Round-trip from | $128 (Breeze Airways) |
|---|---|
One-way from | $69 (Breeze Airways) |
Popular in | March |
Cheapest in | May |
Average price | $290 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from Greenville to Columbus that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Mon 10/12
4:27 pm-5:52 pm
Nonstop1h 25m
Columbus
Fri 10/16
6:32 pm-7:52 pm
Nonstop1h 20m
$138
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Fri 7/17
4:40 pm-6:05 pm
Nonstop1h 25m
Columbus
Mon 7/20
6:45 pm-8:05 pm
Nonstop1h 20m
$178
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Fri 8/14
7:00 am-5:00 pm
2 stops10h 00m
Columbus
Mon 8/17
8:05 am-4:05 pm
2 stops8h 00m
$330
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Sun 10/25
7:15 am-11:21 am
1 stop4h 06m
Columbus
Sun 11/1
8:00 am-1:08 pm
1 stop5h 08m
$347
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Mon 12/21
7:55 pm-12:10 am
1 stop4h 15m
Columbus
Sat 1/2
8:05 am-1:08 pm
1 stop5h 03m
$347
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Fri 11/6
7:15 am-1:28 pm
1 stop6h 13m
Columbus
Sun 11/8
7:00 am-1:08 pm
1 stop6h 08m
$347
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Mon 10/12
8:15 am-11:55 am
1 stop3h 40m
Columbus
Fri 10/16
1:10 pm-9:25 pm
2 stops8h 15m
$352
Cheapest one-way
Quickest one-way
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Fri 8/7
4:40 pm-6:05 pm
Nonstop1h 25m
$89
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Fri 7/24
4:40 pm-6:05 pm
Nonstop1h 25m
$99
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Sun 8/23
3:43 pm-9:43 am
1 stop18h 00m
$134
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Greenville to Columbus
Have a flexible travel schedule? Discover the best time to fly to Columbus from Greenville with our price prediction graph.
GSP-C01
GSP-CMH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to Columbus
GSP-C01
GSP-CMH
What is the cheapest month to book a flight from Greenville to Columbus?
Currently, May is the cheapest month in which you can book a flight from Greenville to Columbus (average of $54). Flying from Greenville to Columbus in April is currently the most expensive (average of $576). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from GSP to CMH?
Find hourly flight availability from Greenville to Columbus. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 27, 2026.
When flying from Greenville to Columbus, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Greenville to Columbus?
Reviews of airlines servicing Columbus
Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated June 27, 2026.
See what other customers who have flown with Breeze Airways,Delta, andUnited Airlines from Greenville to Columbus have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.2
Food
6.7
Entertainment
6.7
Boarding
8.4
Overall
8.2
Crew
8.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Food
6.7
Entertainment
6.7
Boarding
8.4
Overall
8.2
Crew
8.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Food
6.7
Entertainment
6.7
Boarding
8.4
Overall
8.2
Crew
8.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Food
6.7
Entertainment
6.7
Boarding
8.4
Overall
8.2
Crew
8.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Food
6.7
Entertainment
6.7
Boarding
8.4
Overall
8.2
Crew
8.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Greenville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Greenville to Columbus
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Complete your trip
Complete your trip to Columbus by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Greenville to Columbus by cabin class
Find flights from Greenville to Columbus, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and Columbus flights
Browse other Greenville and Columbus flight options. Last updated on June 27, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on June 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Greenville to Columbus
Discover the top 4 airlines that operate flights from Greenville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$54 | Average$158 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$133 | Average$382 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$196 | Average$362 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$492 | FlexibilityNo cancel fee | On-time69% |