$116+ Cheap flights from Greenville (GSP) to Columbus
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — CMH
Mar 5 — Mar 121
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Columbus
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Cheapest flights from Greenville to ColumbusExplore the most affordable flight options available from Greenville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Greenville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
GSP
- CMH
1 stop6h 54m
United Airlines
Mon 4/206:10 am
CMH
- GSP
1 stop3h 48m
United Airlines
Deal found 2/2![United Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:22 pm
GSP
- CMH
1 stop15h 58m
Multiple Airlines
Sun 2/226:15 am
CMH
- GSP
1 stop10h 12m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:12 pm
GSP
- CMH
2 stops24h 29m
Multiple Airlines
Mon 4/206:25 am
CMH
- GSP
1 stop10h 28m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:40 am
GSP
- CMH
1 stop4h 26m
Delta
Mon 3/94:34 pm
CMH
- GSP
1 stop5h 18m
Delta
Deal found 2/1![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:10 am
GSP
- CMH
2 stops10h 00m
Southwest
Mon 4/203:30 pm
CMH
- GSP
2 stops6h 45m
Southwest
Deal found 2/2![Southwest logo]()
$316
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:15 am
GSP
- CMH
2 stops6h 15m
Southwest
Mon 3/95:55 pm
CMH
- GSP
1 stop3h 55m
Southwest
Deal found 2/1![Southwest logo]()
$318
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/710:00 am
GSP
- CMH
1 stop4h 14m
United Airlines
Tue 3/103:08 pm
CMH
- GSP
1 stop4h 20m
United Airlines
Deal found 2/2![United Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:26 pm
GSP
- CMH
1 stop5h 39m
Delta
Sun 4/196:06 am
CMH
- GSP
1 stop6h 15m
Delta
Deal found 2/3![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:00 am
GSP
- CMH
2 stops9h 25m
Southwest
Fri 3/206:10 am
CMH
- GSP
1 stop5h 35m
Southwest
Deal found 2/1![Southwest logo]()
$332
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/71:55 pm
GSP
- CMH
1 stop5h 20m
Southwest
Tue 3/101:45 pm
CMH
- GSP
2 stops8h 55m
Southwest
Deal found 2/2![Southwest logo]()
$336
Best flights from Greenville to ColumbusDiscover carefully curated flight deals from Greenville to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Greenville to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
GSP
- CMH
1 stop6h 54m
United Airlines
Mon 4/206:10 am
CMH
- GSP
1 stop3h 48m
United Airlines
Deal found 2/2![United Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:22 pm
GSP
- CMH
1 stop15h 58m
Multiple Airlines
Sun 2/226:15 am
CMH
- GSP
1 stop10h 12m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:40 am
GSP
- CMH
1 stop4h 26m
Delta
Mon 3/94:34 pm
CMH
- GSP
1 stop5h 18m
Delta
Deal found 2/1![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:10 am
GSP
- CMH
2 stops10h 00m
Southwest
Mon 4/203:30 pm
CMH
- GSP
2 stops6h 45m
Southwest
Deal found 2/2![Southwest logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:12 pm
GSP
- CMH
2 stops24h 29m
Multiple Airlines
Mon 4/206:25 am
CMH
- GSP
1 stop10h 28m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:15 am
GSP
- CMH
2 stops6h 15m
Southwest
Mon 3/95:55 pm
CMH
- GSP
1 stop3h 55m
Southwest
Deal found 2/1![Southwest logo]()
$318
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/710:00 am
GSP
- CMH
1 stop4h 14m
United Airlines
Tue 3/103:08 pm
CMH
- GSP
1 stop4h 20m
United Airlines
Deal found 2/2![United Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:26 pm
GSP
- CMH
1 stop5h 39m
Delta
Sun 4/196:06 am
CMH
- GSP
1 stop6h 15m
Delta
Deal found 2/3![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:35 pm
GSP
- CMH
1 stop4h 50m
Southwest
Fri 3/206:10 am
CMH
- GSP
1 stop5h 35m
Southwest
Deal found 2/1![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/71:55 pm
GSP
- CMH
1 stop5h 20m
Southwest
Tue 3/101:45 pm
CMH
- GSP
2 stops8h 55m
Southwest
Deal found 2/2![Southwest logo]()
$336
Last-minute flights from Greenville to ColumbusDiscover last-minute flight deals from Greenville to Columbus. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Columbus. Data last updated February 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/68:18 pm
GSP
- CMH
1 stop14h 11m
Multiple Airlines
Mon 2/912:03 pm
CMH
- GSP
2 stops8h 04m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:22 pm
GSP
- CMH
1 stop15h 58m
Multiple Airlines
Sun 2/226:15 am
CMH
- GSP
1 stop10h 12m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:40 am
GSP
- CMH
1 stop4h 26m
Delta
Mon 3/94:34 pm
CMH
- GSP
1 stop5h 18m
Delta
Deal found 2/1![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:15 am
GSP
- CMH
2 stops6h 15m
Southwest
Mon 3/95:55 pm
CMH
- GSP
1 stop3h 55m
Southwest
Deal found 2/1![Southwest logo]()
$318
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/710:00 am
GSP
- CMH
1 stop4h 14m
United Airlines
Tue 3/103:08 pm
CMH
- GSP
1 stop4h 20m
United Airlines
Deal found 2/2![United Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/71:55 pm
GSP
- CMH
1 stop5h 20m
Southwest
Tue 3/101:45 pm
CMH
- GSP
2 stops8h 55m
Southwest
Deal found 2/2![Southwest logo]()
$336
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:00 am
GSP
- CMH
2 stops9h 25m
Southwest
Fri 3/206:10 am
CMH
- GSP
1 stop5h 35m
Southwest
Deal found 2/1![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:40 am
GSP
- CMH
1 stop6h 20m
Delta
Sun 3/226:24 pm
CMH
- GSP
1 stop5h 30m
Delta
Deal found 1/31![Delta logo]()
$363
One-way flights from Greenville to ColumbusSearch for one-way flight options from Greenville to Columbus. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Greenville to Columbus. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:18 pm
GSP
- CMH
1 stop12h 12m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$116
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:26 pm
GSP
- CMH
1 stop5h 39m
Delta
Deal found 2/1![Delta logo]()
$133
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:20 am
GSP
- CMH
1 stop5h 09m
American Airlines
Deal found 2/1![American Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:43 pm
GSP
- CMH
3 stops43h 23m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/68:18 pm
GSP
- CMH
1 stop14h 11m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$179
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/237:20 am
GSP
- CMH
1 stop6h 06m
Delta
Deal found 2/2![Delta logo]()
$184
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:20 am
GSP
- CMH
2 stops8h 00m
Southwest
Deal found 2/2![Southwest logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:12 pm
GSP
- CMH
2 stops24h 29m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$200
Find flight deals from Greenville to Columbus
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 3, 2026.
Round-trip from | $215 (Kiwi.com) |
|---|---|
One-way from | $116 (Kiwi.com) |
Popular in | June |
Cheapest in | November |
Average price | $340 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Greenville to Columbus that are best for you.
Fly from
Greenville
Fly to
Columbus
Route
Depart
Return
Price
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Thu 4/16
6:00 am-12:54 pm
1 stop6h 54m
Columbus
Mon 4/20
6:10 am-9:58 am
1 stop3h 48m
$265
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Fri 2/20
6:22 pm-10:20 am
1 stop15h 58m
Columbus
Sun 2/22
6:15 am-4:27 pm
1 stop10h 12m
$267
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Thu 4/16
2:12 pm-2:41 pm
2 stops24h 29m
Columbus
Mon 4/20
6:25 am-4:53 pm
1 stop10h 28m
$271
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Wed 3/4
5:40 am-10:06 am
1 stop4h 26m
Columbus
Mon 3/9
4:34 pm-9:52 pm
1 stop5h 18m
$291
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Thu 4/16
8:10 am-6:10 pm
2 stops10h 00m
Columbus
Mon 4/20
3:30 pm-10:15 pm
2 stops6h 45m
$316
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Wed 3/4
11:15 am-5:30 pm
2 stops6h 15m
Columbus
Mon 3/9
5:55 pm-9:50 pm
1 stop3h 55m
$318
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Sat 3/7
10:00 am-2:14 pm
1 stop4h 14m
Columbus
Tue 3/10
3:08 pm-7:28 pm
1 stop4h 20m
$321
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Wed 3/18
12:35 pm-5:25 pm
1 stop4h 50m
Columbus
Fri 3/20
6:10 am-11:45 am
1 stop5h 35m
$321
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Fri 4/17
6:26 pm-12:05 am
1 stop5h 39m
Columbus
Sun 4/19
6:06 am-12:21 pm
1 stop6h 15m
$327
GreenvilleColumbus
GSP - CMH
GSPCMH
Greenville
Sat 3/7
1:55 pm-7:15 pm
1 stop5h 20m
Columbus
Tue 3/10
1:45 pm-10:40 pm
2 stops8h 55m
$336
Showing 1-10 of 18 results
Best time to book a flight from Greenville to Columbus
Have a flexible travel schedule? Discover the best time to fly to Columbus from Greenville with our price prediction graph.
GSP-C01
GSP-CMH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to Columbus
GSP-C01
GSP-CMH
What is the cheapest month to book a flight from Greenville to Columbus?
Currently, March is the cheapest month in which you can book a flight from Greenville to Columbus (average of $118). Flying from Greenville to Columbus in January is currently the most expensive (average of $232). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to Columbus?
Reviews of airlines servicing Columbus
Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated February 3, 2026.
See what other customers who have flown with Southwest, Delta, and American Airlines from Greenville to Columbus have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Greenville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Greenville to Columbus
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Complete your trip
Complete your trip to Columbus by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Greenville to Columbus by cabin class
Find flights from Greenville to Columbus, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and Columbus flights
Browse other Greenville and Columbus flight options. Last updated on February 3, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on February 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Greenville to Columbus
Discover the top 3 airlines that operate flights from Greenville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$211 | Average$336 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$211 | Average$377 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$216 | Average$264 | FlexibilityNo cancel fee | On-time63% |