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Columbia

$248+ Cheap flights from La Crosse to Columbia, MO (LSE - COU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — COU
Apr 13 — Apr 201
Mon 4/13
Mon 4/20
1 adult, Economy
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Cheap flight deals from La Crosse to Columbia

Cheapest flights from La Crosse to Columbia
Explore the most affordable flight options available from La Crosse to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.

This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:09 am
LSE
-
COU
1 stop4h 19m
American Airlines
Sat 3/286:50 pm
COU
-
LSE
1 stop4h 46m
American Airlines
Deal found 3/9$258
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:09 am
LSE
-
COU
1 stop4h 24m
American Airlines
Mon 3/306:00 am
COU
-
LSE
1 stop5h 01m
American Airlines
Deal found 3/11$278
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:42 am
LSE
-
COU
1 stop14h 51m
United Airlines
Mon 12/213:16 pm
COU
-
LSE
1 stop26h 54m
United Airlines
Deal found 3/12$644

Find flight deals from La Crosse to Columbia

Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 14, 2026.

Round-trip from

$258
(American Airlines)

One-way from

$248
(American Airlines)
From La Crosse to Columbia Regional
Search Deals
One-way flight from La Crosse to Columbia Regional
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Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from La Crosse to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

La CrosseColumbia

LSE - COU

LSECOU

La Crosse

Tue 3/24

5:09 am-9:28 am

1 stop4h 19m

Columbia Regional

Sat 3/28

6:50 pm-11:36 pm

1 stop4h 46m

$258

La CrosseColumbia

LSE - COU

LSECOU

La Crosse

Thu 3/26

5:09 am-9:33 am

1 stop4h 24m

Columbia Regional

Mon 3/30

12:27 pm-11:36 pm

2 stops11h 09m

$403
Cheapest one-way
Quickest one-way

La CrosseColumbia

LSE - COU

LSECOU

La Crosse

Sat 4/4

11:35 am-6:20 pm

1 stop6h 45m

$248

La CrosseColumbia

LSE - COU

LSECOU

La Crosse

Fri 4/3

6:29 pm-6:20 pm

1 stop23h 51m

$402

La CrosseColumbia

LSE - COU

LSECOU

La Crosse

Tue 4/7

10:05 am-4:51 pm

2 stops30h 46m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Sorted by cheapest first

Best time to book a flight from La Crosse to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from La Crosse to Columbia, Missouri?

    There are many flights that can get you from La Crosse to Columbia, Missouri in 4h 19m. Fly via American Airlines to get the fastest option. The distance between La Crosse and Columbia, Missouri is about 353 mi.

  • Can I find deals for flights from La Crosse to Columbia that include hotel bookings?

    Yes. In addition to deals on La Crosse to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Columbia?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Columbia.

  • Can I find deals for business class flights from La Crosse to Columbia?

    Yes. Cheapflights offers flight deals from La Crosse to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
Jefferson City

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