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$54+ Cheap flights from Knoxville (TYS) to Colorado

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DEN
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Knoxville to Colorado

Cheapest flights from Knoxville to Colorado
Explore the most affordable flight options available from Knoxville to Colorado. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Priceline deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:52 pmTYS - DEN
Nonstop3h 31mFrontier
Sun 12/711:12 amDEN - TYS
Nonstop2h 45mFrontier
Deal found 10/25$102
This Frontier deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:17 pmTYS - DEN
Nonstop3h 17mFrontier
Fri 11/2111:07 amDEN - TYS
Nonstop2h 46mFrontier
Deal found 10/26$108
This Cheapflightsfares deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/97:00 amTYS - DEN
Nonstop3h 15mAllegiant Air
Thu 11/139:05 amDEN - TYS
Nonstop2h 39mAllegiant Air
Deal found 10/26$111
This Frontier deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:17 pmTYS - DEN
Nonstop3h 17mFrontier
Sun 11/161:36 pmDEN - TYS
Nonstop2h 46mFrontier
Deal found 10/26$112
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/97:00 amTYS - DEN
Nonstop3h 15mMultiple Airlines
Thu 11/131:36 pmDEN - TYS
Nonstop2h 46mMultiple Airlines
Deal found 10/27$113
This Priceline deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:17 pmTYS - DEN
Nonstop3h 17mFrontier
Sun 11/91:36 pmDEN - TYS
Nonstop2h 46mFrontier
Deal found 10/26$114
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/97:00 amTYS - DEN
Nonstop3h 15mAllegiant Air
Thu 11/208:45 amDEN - TYS
Nonstop2h 39mAllegiant Air
Deal found 10/26$117
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/97:00 amTYS - DEN
Nonstop3h 15mMultiple Airlines
Fri 11/2111:07 amDEN - TYS
Nonstop2h 46mMultiple Airlines
Deal found 10/26$118
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:17 pmTYS - DEN
Nonstop3h 17mMultiple Airlines
Thu 11/208:45 amDEN - TYS
Nonstop2h 39mMultiple Airlines
Deal found 10/26$124
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:10 amTYS - GJT
1 stop6h 56mAmerican Airlines
Sat 11/154:55 pmGJT - TYS
1 stop5h 13mAmerican Airlines
Deal found 10/27$269
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:55 pmTYS - MTJ
1 stop5h 25mUnited Airlines
Sun 11/167:15 amMTJ - TYS
1 stop6h 36mUnited Airlines
Deal found 10/28$269
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/119:10 amTYS - GJT
2 stops9h 44mUnited Airlines
Sat 11/155:30 amGJT - TYS
1 stop7h 12mUnited Airlines
Deal found 10/27$274

Cheap flight deals from Knoxville to Colorado

Keep the following information in mind while searching for Knoxville to Colorado flight deals. Data was last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$102
(Priceline)

One-way from

$54
(Cheapflightsfares)

Popular in

December

Cheapest in

May

Average price

$242

Good round-trip deal

$199 or less

Good one-way deal

$141 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Denver Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Denver Intl flights.
Search Deals
From Knoxville McGhee Tyson to Colorado
Search Deals
One-way flight from Knoxville McGhee Tyson to Colorado
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($9 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Colorado.
Search Deals
Price to beat on a one-way flight from Knoxville McGhee Tyson to Colorado.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Colorado that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Knoxville to Colorado that are best for you.

Fly from

Knoxville

Fly to

Colorado

Route

Depart

Return

Price

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Fri 12/5

7:59 pm-12:07 am

1 stop6h 08m

Denver Intl

Sun 12/7

12:50 am-9:38 am

1 stop6h 48m

$219

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Fri 1/9

6:45 am-11:44 am

1 stop6h 59m

Denver Intl

Thu 1/15

5:30 pm-10:31 pm

Nonstop3h 01m

$239

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Fri 11/21

8:07 pm-12:02 am

1 stop5h 55m

Denver Intl

Thu 11/27

7:05 am-2:48 pm

1 stop5h 43m

$249

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Sun 11/23

5:35 am-9:34 am

1 stop5h 59m

Denver Intl

Thu 11/27

7:05 am-2:48 pm

1 stop5h 43m

$249

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Sat 11/22

3:53 pm-8:38 pm

1 stop6h 45m

Denver Intl

Thu 11/27

7:05 am-1:44 pm

1 stop4h 39m

$249

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Tue 11/11

4:58 pm-6:25 pm

Nonstop3h 27m

Denver Intl

Tue 11/18

1:35 pm-11:59 pm

1 stop8h 24m

$254

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Sun 11/23

5:35 am-9:34 am

1 stop5h 59m

Denver Intl

Fri 11/28

6:00 am-1:44 pm

1 stop5h 44m

$264

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Fri 11/14

5:36 pm-10:59 pm

1 stop7h 23m

Denver Intl

Tue 11/18

6:48 am-4:46 pm

1 stop7h 58m

$264

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Tue 11/11

7:39 am-2:15 pm

1 stop8h 36m

Denver Intl

Wed 11/19

11:23 am-8:35 pm

1 stop7h 12m

$264

KnoxvilleGrand Junction

TYS - GJT

TYSGJT

Knoxville McGhee Tyson

Tue 11/11

5:10 am-10:06 am

1 stop6h 56m

Grand Junction Regnl

Sat 11/15

4:55 pm-12:08 am

1 stop5h 13m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 40 results
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Best time to book a flight from Knoxville to Colorado

Have a flexible travel schedule? Discover the best time to fly to Colorado from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Colorado

What is the cheapest month to book a flight from Knoxville to Colorado?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Colorado (average of $59). Flying from Knoxville to Colorado in May is currently the most expensive (average of $106). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CO?

Find hourly flight availability from Knoxville to Colorado. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 35% on flights from Knoxville to Colorado by exploring options for tickets in the evening.

What is the cheapest day to fly from Knoxville to Colorado?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Colorado. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Colorado flight should consider departing on Friday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Colorado

Get insights into the airlines that provide service to Colorado. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Colorado. Reviews last updated October 28, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Colorado have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,995 reviews
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,996 reviews
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Allegiant Air
7.2
Good
695 reviews
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Frontier
5.8
Fair
3,122 reviews
Delta
7.9
Good
7,995 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Colorado. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Colorado?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Colorado. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How popular is this Knoxville to Colorado flight route?

    Within the past month, 22 users have taken a look at flights from Knoxville McGhee Tyson to Colorado.

  • How long is the flight from Knoxville to Colorado?

    A quick flight from Knoxville to Colorado can take about 6h 08m. Delta provides one of the quickest options available for as low as $219. The distance from Knoxville to Colorado is about 1159 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Knoxville to Colorado one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $58. Delta flights start at $110 while deals on United Airlines start at $151 one-way.

  • What are the most popular routes from Knoxville to Colorado?

    The most popular flight routes from Knoxville to Colorado are Knoxville McGhee Tyson - Denver Intl, Knoxville McGhee Tyson - Grand Junction Regnl and Knoxville McGhee Tyson - Colorado Springs.

  • What are the most reliable airlines from Knoxville to Colorado?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Knoxville to Colorado on time: Allegiant Air (100%), SkyWest Airlines (95%), United Airlines (71%).

  • What are the cheapest flights from Knoxville to Colorado?

    Looking for the cheapest flight from Knoxville to Colorado? While on average our users pay $282, our data indicates the cheapest price to be $72. The most popular route (Knoxville McGhee Tyson - Denver Intl), is priced around $96.

  • Can I find deals for flights from Knoxville to Colorado that include hotel bookings?

    Yes. In addition to deals on Knoxville to Colorado flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Colorado?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Colorado.

  • Can I find deals for business class flights from Knoxville to Colorado?

    Yes. Cheapflights offers flight deals from Knoxville to Colorado by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Colorado?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Colorado (average of $59). Flying from Knoxville to Colorado in May is currently the most expensive (average of $106). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Colorado

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Knoxville to Colorado

Discover the top 5 airlines that operate flights from Knoxville to Colorado. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$74Average$146FlexibilityNo cancel feeOn-time88%
FrontierCheapest$77Average$176FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$215Average$452FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$231Average$504FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$321FlexibilityNo cancel feeOn-timeN/A

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