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$755+ Cheap flights from Missouri to Chile

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — SCL
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Missouri to Chile

Cheapest flights from Missouri to Chile
Explore the most affordable flight options available from Missouri to Chile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This LATAM Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amSTL - SCL
1 stop22h 40mLATAM Airlines
Tue 1/611:10 pmSCL - STL
1 stop14h 55mLATAM Airlines
Deal found 12/15$1,034
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:35 pmMCI - SCL
2 stops35h 15mUnited Airlines
Tue 12/2310:45 pmSCL - MCI
1 stop21h 09mUnited Airlines
Deal found 12/17$1,409
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:42 amMCI - SCL
2 stops15h 53mDelta
Mon 1/59:30 pmSCL - MCI
1 stop15h 46mDelta
Deal found 12/17$1,429
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:44 amMCI - SCL
1 stop19h 01mAmerican Airlines
Mon 1/511:55 pmSCL - MCI
1 stop14h 09mAmerican Airlines
Deal found 12/16$1,474
This Priceline deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:59 amMCI - SCL
2 stops24h 06mLATAM Airlines
Tue 12/237:15 amSCL - MCI
3 stops31h 21mLATAM Airlines
Deal found 12/17$1,739
This KAYAK deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:00 amMCI - SCL
2 stops18h 35mLATAM Airlines
Mon 1/510:15 pmSCL - MCI
2 stops27h 36mLATAM Airlines
Deal found 12/17$1,767
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amSTL - SCL
1 stop23h 50mUnited Airlines
Tue 1/610:45 pmSCL - STL
1 stop13h 37mUnited Airlines
Deal found 12/17$1,823
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:00 amSTL - SCL
2 stops21h 00mDelta
Tue 1/68:15 amSCL - STL
2 stops18h 24mDelta
Deal found 12/15$1,913
This FlightHub deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amSTL - SCL
1 stop21h 10mLATAM Airlines
Sat 1/34:35 pmSCL - STL
2 stops34h 07mLATAM Airlines
Deal found 12/15$1,989
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:00 amSTL - SCL
1 stop21h 10mLATAM Airlines
Thu 1/112:20 amSCL - STL
2 stops35h 38mLATAM Airlines
Deal found 12/16$2,059
This FlightHub deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:13 pmSTL - SCL
2 stops19h 17mLATAM Airlines
Thu 1/112:20 amSCL - STL
2 stops26h 22mLATAM Airlines
Deal found 12/18$2,075

Find flight deals from Missouri to Chile

Keep the following information in mind while searching for Missouri to Chile flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$755
(United Airlines)

Popular in

February

Cheapest in

March

Average price

$944
Provider with most accurate pricing for Lambert-St Louis-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Santiago Arturo Merino Benitez flights.
Search Deals
From Missouri to Chile
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Chile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Missouri to Chile that are best for you.

Fly from

Missouri

Fly to

Chile

Route

Depart

Return

Price

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

6:00 am-7:50 am

1 stop23h 50m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-9:21 am

1 stop13h 36m

$755

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Wed 1/14

6:00 am-6:10 am

1 stop21h 10m

Santiago Arturo Merino Benitez

Wed 1/28

11:10 pm-4:15 pm

1 stop20h 05m

$764

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Wed 1/14

6:00 am-6:25 am

2 stops21h 25m

Santiago Arturo Merino Benitez

Wed 1/28

6:30 pm-11:20 am

2 stops19h 50m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 1/12

3:45 pm-7:40 am

1 stop12h 55m

Santiago Arturo Merino Benitez

Tue 1/20

9:30 pm-4:07 pm

1 stop21h 37m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 1/12

9:59 am-5:50 am

2 stops16h 51m

Santiago Arturo Merino Benitez

Mon 1/26

3:00 pm-8:53 am

2 stops20h 53m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Tue 1/13

7:10 am-7:40 am

1 stop21h 30m

Santiago Arturo Merino Benitez

Tue 1/20

9:30 pm-8:53 am

1 stop14h 23m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 1/14

9:59 am-6:10 am

1 stop17h 11m

Santiago Arturo Merino Benitez

Tue 1/20

12:20 am-4:07 pm

2 stops18h 47m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 1/12

7:10 am-6:10 am

1 stop20h 00m

Santiago Arturo Merino Benitez

Thu 1/22

9:30 pm-5:50 pm

1 stop23h 20m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Tue 1/13

5:00 pm-7:40 am

1 stop11h 40m

Santiago Arturo Merino Benitez

Wed 1/21

11:10 pm-11:04 am

1 stop14h 54m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 1/14

6:00 am-6:10 am

1 stop21h 10m

Santiago Arturo Merino Benitez

Tue 1/20

11:10 pm-11:54 am

1 stop15h 44m

$764

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 21 results
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Best time to book a flight from Missouri to Chile

Have a flexible travel schedule? Discover the best time to fly to Chile from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Chile

What is the cheapest month to book a flight from Missouri to Chile?

Currently, March is the cheapest month in which you can book a flight from Missouri to Chile (average of $598). Flying from Missouri to Chile in October is currently the most expensive (average of $924). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CL?

Find hourly flight availability from Missouri to Chile. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s typically best to fly out from Missouri to Chile in the evening. Doing so could potentially save you 48% on the flight price compared to flying in the afternoon, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Chile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Chile?

    A quick flight from Missouri to Chile can take about 21h 10m. United Airlines provides one of the quickest options available for as low as $764. Missouri and Chile are separated by a distance of 5089 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Missouri to Chile that include hotel bookings?

    Yes. In addition to deals on Missouri to Chile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Chile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Chile.

  • Can I find deals for business class flights from Missouri to Chile?

    Yes. Cheapflights offers flight deals from Missouri to Chile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Chile?

    Currently, March is the cheapest month in which you can book a flight from Missouri to Chile (average of $598). Flying from Missouri to Chile in October is currently the most expensive (average of $924). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Chile

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Chile

Discover the top 4 airlines that operate flights from Missouri to Chile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$689Average$995FlexibilityNo cancel feeOn-time71%
DeltaCheapest$755Average$1,030FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$764Average$1,047FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$823Average$908FlexibilityNo cancel feeOn-time81%

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