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$360+ Cheap flights from Missouri to Chile

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SCL
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheap flight deals from Missouri to Chile

Keep the following information in mind while searching for Missouri to Chile flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$738
(LATAM Airlines)

One-way from

$360
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$952
Provider with most accurate pricing for Lambert-St Louis-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Santiago Arturo Merino Benitez flights.
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From Missouri to Chile
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One-way flight from Missouri to Chile
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Highest demand for flights based on searches. 6% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Missouri to Chile

Cheapest flights from Missouri to Chile
Explore the most affordable flight options available from Missouri to Chile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This FlightHub deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2711:04 amSTL - SCL
2 stops14h 26mLATAM Airlines
Mon 12/810:35 amSCL - STL
2 stops16h 07mLATAM Airlines
Deal found 11/2$753
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/24:30 pmMCI - SCL
1 stop13h 20mUnited Airlines
Tue 12/910:45 pmSCL - MCI
1 stop18h 32mUnited Airlines
Deal found 11/2$764
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:13 amMCI - SCL
1 stop23h 32mAmerican Airlines
Tue 1/1310:30 pmSCL - MCI
1 stop27h 42mAmerican Airlines
Deal found 11/2$765
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:50 amJLN - SCL
2 stops22h 00mUnited Airlines
Mon 12/810:45 pmSCL - JLN
2 stops27h 42mUnited Airlines
Deal found 11/1$769
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/258:00 amMCI - SCL
2 stops21h 50mUnited Airlines
Mon 12/110:45 pmSCL - MCI
1 stop20h 53mUnited Airlines
Deal found 11/2$769
This KAYAK deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1010:15 amMCI - SCL
3 stops25h 15mLATAM Airlines
Thu 1/1511:30 pmSCL - MCI
2 stops20h 27mLATAM Airlines
Deal found 10/31$802
This Orbitz deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/29:30 amSTL - SCL
3 stops26h 00mLATAM Airlines
Tue 12/97:15 amSCL - STL
3 stops30h 30mLATAM Airlines
Deal found 11/2$813
This Mytrip deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:01 pmMCI - SCL
3 stops29h 59mMultiple Airlines
Tue 12/2312:30 pmSCL - MCI
2 stops31h 40mMultiple Airlines
Deal found 10/31$877
This Orbitz deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:50 amMCI - SCL
1 stop22h 50mLATAM Airlines
Tue 12/239:30 pmSCL - MCI
1 stop15h 22mLATAM Airlines
Deal found 10/31$914
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amMCI - SCL
3 stops32h 25mMultiple Airlines
Mon 12/16:00 amSCL - MCI
3 stops33h 03mMultiple Airlines
Deal found 11/2$923
This KAYAK deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amSTL - SCL
3 stops29h 30mLATAM Airlines
Mon 1/54:35 amSCL - STL
2 stops22h 04mLATAM Airlines
Deal found 10/31$1,131
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:09 pmSTL - SCL
1 stop12h 56mAmerican Airlines
Sat 11/2211:15 pmSCL - STL
1 stop19h 14mAmerican Airlines
Deal found 11/1$1,164

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Chile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Missouri to Chile that are best for you.

Fly from

Missouri

Fly to

Chile

Route

Depart

Return

Price

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 11/27

11:04 am-7:40 am

1 stop17h 36m

Santiago Arturo Merino Benitez

Mon 12/8

10:35 am-11:42 pm

2 stops16h 07m

$753

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Wed 2/4

12:02 pm-3:30 pm

2 stops24h 28m

Santiago Arturo Merino Benitez

Tue 2/17

11:15 pm-4:21 pm

1 stop20h 06m

$764

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Mon 2/2

8:50 am-8:50 am

1 stop21h 00m

Santiago Arturo Merino Benitez

Tue 2/17

10:45 pm-4:25 pm

1 stop20h 40m

$764

Kansas CitySantiago

MCI - SCL

MCISCL

Kansas City

Wed 1/7

11:42 am-7:50 am

1 stop17h 08m

Santiago Arturo Merino Benitez

Wed 1/14

10:30 pm-11:05 am

1 stop15h 35m

$764

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Thu 2/5

12:02 pm-9:55 pm

2 stops30h 53m

Santiago Arturo Merino Benitez

Thu 2/19

11:15 pm-11:20 am

1 stop15h 05m

$764

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Tue 3/3

5:06 pm-2:05 pm

2 stops17h 59m

Santiago Arturo Merino Benitez

Tue 3/24

11:15 pm-11:14 am

1 stop13h 59m

$764

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Thu 2/5

8:50 am-8:50 am

1 stop21h 00m

Santiago Arturo Merino Benitez

Thu 2/19

10:45 pm-1:57 pm

1 stop18h 12m

$764

SpringfieldSantiago

SGF - SCL

SGFSCL

Springfield-Branson

Tue 2/3

5:05 pm-3:30 pm

2 stops19h 25m

Santiago Arturo Merino Benitez

Mon 2/16

11:15 pm-11:20 am

1 stop15h 05m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 12/11

11:10 am-8:50 am

1 stop18h 40m

Santiago Arturo Merino Benitez

Mon 12/15

10:45 pm-4:04 pm

1 stop20h 19m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 12/11

6:00 am-6:35 am

2 stops21h 35m

Santiago Arturo Merino Benitez

Mon 12/15

6:40 am-11:42 pm

2 stops20h 02m

$764

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 29 results
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Best time to book a flight from Missouri to Chile

Have a flexible travel schedule? Discover the best time to fly to Chile from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Chile

What is the cheapest month to book a flight from Missouri to Chile?

Currently, December is the cheapest month in which you can book a flight from Missouri to Chile (average of $552). Flying from Missouri to Chile in October is currently the most expensive (average of $924). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CL?

Find hourly flight availability from Missouri to Chile. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

It’s typically best to fly out from Missouri to Chile in the evening. Doing so could potentially save you 48% on the flight price compared to flying in the afternoon, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Chile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Chile?

    A quick flight from Missouri to Chile can take about 17h 36m. LATAM Airlines provides one of the quickest options available for as low as $753. Missouri and Chile are separated by a distance of 5137 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Missouri to Chile that include hotel bookings?

    Yes. In addition to deals on Missouri to Chile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Chile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Chile.

  • Can I find deals for business class flights from Missouri to Chile?

    Yes. Cheapflights offers flight deals from Missouri to Chile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Chile?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Chile (average of $552). Flying from Missouri to Chile in October is currently the most expensive (average of $924). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Chile

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Chile

Discover the top 4 airlines that operate flights from Missouri to Chile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$689Average$1,030FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$764Average$925FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$773Average$1,617FlexibilityNo cancel feeOn-time81%
DeltaCheapest$802Average$1,013FlexibilityNo cancel feeOn-timeN/A

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