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$372+ Cheap flights from Des Moines (DSM) to Chile

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SCL
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Des Moines to Chile

Cheapest flights from Des Moines to Chile
Explore the most affordable flight options available from Des Moines to Chile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:00 amDSM - SCL
1 stop23h 45mAmerican Airlines
Thu 12/1810:25 pmSCL - DSM
1 stop28h 33mAmerican Airlines
Deal found 10/27$763
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:53 pmDSM - SCL
1 stop14h 57mUnited Airlines
Thu 12/1810:45 pmSCL - DSM
1 stop18h 34mUnited Airlines
Deal found 10/28$764
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:00 amDSM - SCL
1 stop23h 55mAmerican Airlines
Fri 12/1911:15 pmSCL - DSM
1 stop18h 53mAmerican Airlines
Deal found 10/28$843
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:50 pmDSM - SCL
2 stops35h 00mUnited Airlines
Sat 12/2010:45 pmSCL - DSM
1 stop26h 45mUnited Airlines
Deal found 10/29$858
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:50 pmDSM - SCL
2 stops59h 00mUnited Airlines
Fri 12/1910:45 pmSCL - DSM
2 stops18h 48mUnited Airlines
Deal found 10/28$865
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:16 pmDSM - PUQ
2 stops31h 50mLATAM Airlines
Wed 12/174:08 amPUQ - DSM
2 stops33h 30mLATAM Airlines
Deal found 10/27$1,124
This SmartFares deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:34 amDSM - PUQ
2 stops34h 06mLATAM Airlines
Thu 12/183:19 amPUQ - DSM
2 stops34h 19mLATAM Airlines
Deal found 10/28$1,518
This lastminute.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:23 amDSM - PUQ
2 stops32h 38mLATAM Airlines
Sat 12/205:25 pmPUQ - DSM
2 stops26h 50mLATAM Airlines
Deal found 10/29$1,770
This Ovago deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/302:13 pmDSM - PUQ
2 stops36h 07mLATAM Airlines
Sat 11/111:59 pmPUQ - DSM
2 stops40h 29mLATAM Airlines
Deal found 10/26$1,831
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:00 amDSM - PUQ
3 stops31h 40mMultiple Airlines
Thu 12/183:19 amPUQ - DSM
3 stops37h 36mMultiple Airlines
Deal found 10/28$1,851

Cheap flight deals from Des Moines to Chile

Keep the following information in mind while searching for Des Moines to Chile flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$763
(American Airlines)

One-way from

$372
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$814
Provider with most accurate pricing for Des Moines-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Santiago Arturo Merino Benitez flights.
Search Deals
From Des Moines to Chile
Search Deals
One-way flight from Des Moines to Chile
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($67 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($63 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Chile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Des Moines to Chile that are best for you.

Fly from

Des Moines

Fly to

Chile

Route

Depart

Return

Price

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 12/11

5:00 am-7:45 am

1 stop23h 45m

Santiago Arturo Merino Benitez

Thu 12/18

10:25 pm-11:58 pm

1 stop28h 33m

$763

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 1/1

1:15 pm-2:05 pm

2 stops21h 50m

Santiago Arturo Merino Benitez

Wed 3/25

12:25 am-10:28 pm

2 stops24h 03m

$764

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Tue 1/6

3:04 pm-8:50 am

1 stop14h 46m

Santiago Arturo Merino Benitez

Wed 3/25

9:45 pm-2:20 pm

1 stop18h 35m

$764

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 1/1

1:15 pm-2:05 pm

2 stops21h 50m

Santiago Arturo Merino Benitez

Wed 3/25

11:15 pm-4:30 pm

1 stop19h 15m

$764

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 12/11

8:15 am-8:50 am

1 stop21h 35m

Santiago Arturo Merino Benitez

Thu 12/18

10:45 pm-2:19 pm

1 stop18h 34m

$764

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 1/1

1:15 pm-6:10 am

1 stop13h 55m

Santiago Arturo Merino Benitez

Sun 3/29

11:25 pm-10:28 pm

2 stops25h 03m

$764

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Tue 1/6

5:16 pm-5:25 pm

2 stops21h 09m

Santiago Arturo Merino Benitez

Thu 3/26

6:30 pm-10:23 am

2 stops17h 53m

$764

Des MoinesPunta Arenas

DSM - PUQ

DSMPUQ

Des Moines

Thu 12/11

2:16 pm-1:06 am

2 stops31h 50m

Punta Arenas Pres Ibanez

Wed 12/17

4:08 am-10:38 am

2 stops33h 30m

$1,124

Des MoinesPunta Arenas

DSM - PUQ

DSMPUQ

Des Moines

Fri 12/12

5:34 am-6:40 pm

2 stops34h 06m

Punta Arenas Pres Ibanez

Thu 12/18

3:19 am-10:38 am

2 stops34h 19m

$1,518

Des MoinesPunta Arenas

DSM - PUQ

DSMPUQ

Des Moines

Sat 12/13

11:23 am-11:01 pm

2 stops32h 38m

Punta Arenas Pres Ibanez

Sat 12/20

5:25 pm-5:15 pm

2 stops26h 50m

$1,770

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 21 results
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Best time to book a flight from Des Moines to Chile

Have a flexible travel schedule? Discover the best time to fly to Chile from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Chile
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Chile

Get insights into the airlines that provide service to Chile. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chile. Reviews last updated October 29, 2025.
Read reviews from past customers who have flown LATAM Airlines from Des Moines to Chile. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,871 reviews

Overall

7.5

Comfort

7.3

Entertainment

7.0

Food

6.7

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP
LATAM Airlines
7.5
Good
1,871 reviews
LATAM Airlines
7.5
Good
1,871 reviews

Overall

7.5

Comfort

7.3

Entertainment

7.0

Food

6.7

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Chile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Chile?

    For a flight from Des Moines to Chile, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Chile?

    A quick flight from Des Moines to Chile can take about 14h 46m. American Airlines provides one of the quickest options available for as low as $764. Des Moines and Chile are separated by a distance of 5374 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Des Moines to Chile that include hotel bookings?

    Yes. In addition to deals on Des Moines to Chile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Chile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Chile.

  • Can I find deals for business class flights from Des Moines to Chile?

    Yes. Cheapflights offers flight deals from Des Moines to Chile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Des Moines to Chile

Discover the top airline that operate flights from Des Moines to Chile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$814Average$1,203FlexibilityNo cancel feeOn-time81%

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