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$368+ Cheap flights from Des Moines (DSM) to Chile

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SCL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Des Moines to Chile

Cheapest flights from Des Moines to Chile
Explore the most affordable flight options available from Des Moines to Chile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:46 pmDSM - SCL
2 stops59h 04mUnited Airlines
Thu 12/2510:45 pmSCL - DSM
1 stop18h 34mUnited Airlines
Deal found 12/11$984
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:35 amDSM - SCL
1 stop23h 05mDelta
Thu 12/2511:10 pmSCL - DSM
1 stop17h 28mDelta
Deal found 12/11$1,124
This Priceline deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:23 amDSM - SCL
2 stops39h 12mLATAM Airlines
Thu 12/253:05 pmSCL - DSM
3 stops34h 26mLATAM Airlines
Deal found 12/11$1,554
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:46 pmDSM - SCL
2 stops35h 04mUnited Airlines
Mon 1/510:45 pmSCL - DSM
1 stop26h 45mUnited Airlines
Deal found 12/10$1,604
This Priceline deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2711:23 amDSM - SCL
3 stops24h 07mLATAM Airlines
Mon 1/510:15 pmSCL - DSM
2 stops39h 23mLATAM Airlines
Deal found 12/10$1,837
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amDSM - SCL
1 stop24h 25mAmerican Airlines
Mon 1/511:15 pmSCL - DSM
1 stop19h 00mAmerican Airlines
Deal found 12/10$1,958
This KAYAK deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/282:18 pmDSM - SCL
3 stops28h 32mLATAM Airlines
Fri 1/212:20 amSCL - DSM
2 stops37h 18mLATAM Airlines
Deal found 12/10$2,204

Find flight deals from Des Moines to Chile

Keep the following information in mind while searching for Des Moines to Chile flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$797
(Expedia)

One-way from

$368
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$1,652
Provider with most accurate pricing for Des Moines-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Santiago Arturo Merino Benitez flights.
Search Deals
From Des Moines to Chile
Search Deals
One-way flight from Des Moines to Chile
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($59 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Chile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to Chile that are best for you.

Fly from

Des Moines

Fly to

Chile

Route

Depart

Return

Price

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sun 1/25

5:16 pm-7:40 am

1 stop35h 24m

Santiago Arturo Merino Benitez

Sun 2/1

10:15 pm-10:29 pm

2 stops27h 14m

$797

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sun 1/25

6:48 pm-8:50 am

2 stops35h 02m

Santiago Arturo Merino Benitez

Sun 2/1

10:45 pm-10:30 pm

1 stop26h 45m

$818

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sun 1/25

11:26 am-7:40 am

1 stop17h 14m

Santiago Arturo Merino Benitez

Sun 2/1

11:10 pm-4:28 pm

1 stop20h 18m

$844

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sun 1/25

6:30 am-7:50 am

1 stop22h 20m

Santiago Arturo Merino Benitez

Sun 2/1

10:30 pm-5:06 pm

1 stop21h 36m

$844

Des MoinesPunta Arenas

DSM - PUQ

DSMPUQ

Des Moines

Sat 1/24

1:03 pm-9:26 am

3 stops65h 23m

Punta Arenas Pres Ibanez

Sat 1/31

11:15 pm-10:29 pm

2 stops50h 14m

$2,014

Des MoinesPunta Arenas

DSM - PUQ

DSMPUQ

Des Moines

Sun 1/25

5:16 pm-11:06 pm

2 stops50h 50m

Punta Arenas Pres Ibanez

Sat 1/31

1:19 am-10:41 am

2 stops36h 22m

$2,020

Des MoinesPunta Arenas

DSM - PUQ

DSMPUQ

Des Moines

Sat 1/24

1:03 pm-2:05 am

2 stops34h 02m

Punta Arenas Pres Ibanez

Sat 1/31

11:15 pm-10:29 pm

2 stops50h 14m

$2,656

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sun 1/25

4:30 pm-8:44 pm

3 stops49h 14m

$368

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sun 1/25

3:04 pm-8:50 am

1 stop14h 46m

$578

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sat 12/20

6:46 pm-8:50 am

2 stops59h 04m

$664

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 11 results
1
2

Best time to book a flight from Des Moines to Chile

Have a flexible travel schedule? Discover the best time to fly to Chile from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Chile
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Chile

Get insights into the airlines that provide service to Chile. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chile. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown LATAM Airlines from Des Moines to Chile. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,887 reviews

Food

6.7

Comfort

7.4

Crew

8.1

Boarding

7.6

Entertainment

7.0

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP
LATAM Airlines
7.5
Good
1,887 reviews
LATAM Airlines
7.5
Good
1,887 reviews

Food

6.7

Comfort

7.4

Crew

8.1

Boarding

7.6

Entertainment

7.0

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Chile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Chile?

    For a flight from Des Moines to Chile, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Chile?

    A quick flight from Des Moines to Chile can take about 35h 02m. LATAM Airlines provides one of the quickest options available for as low as $818. Des Moines and Chile are separated by a distance of 5374 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Des Moines to Chile that include hotel bookings?

    Yes. In addition to deals on Des Moines to Chile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Chile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Chile.

  • Can I find deals for business class flights from Des Moines to Chile?

    Yes. Cheapflights offers flight deals from Des Moines to Chile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Des Moines to Chile

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Top airline flying from Des Moines to Chile

Discover the top airline that operate flights from Des Moines to Chile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$814Average$1,241FlexibilityNo cancel feeOn-time81%

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