$127+ Cheap flights from Mesa, AZ to Chicago (CHI)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — CHI
Oct 17 — Oct 241
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Mesa to Chicago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Chicago are usually found in February or January, booked 39 days in advance, depart on a Thursday or Friday and return on a Saturday
Cheap flight deals from Mesa to Chicago
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to ChicagoExplore the most affordable flight options available from Mesa to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Mesa to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:32 pm -
Nonstop3h 27m
Thu 10/158:01 pm -
1 stop22h 16m
Deal found 9/13![Frontier logo]()
$205
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:45 pm -
1 stop5h 55m
Mon 10/267:15 pm -
Nonstop3h 45m
Deal found 9/16![Southwest logo]()
$241
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:29 pm -
1 stop6h 55m
Thu 10/224:20 pm -
Nonstop4h 07m
Deal found 9/16![Frontier logo]()
$242
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:45 pm -
1 stop5h 55m
Tue 10/276:55 am -
Nonstop3h 50m
Deal found 9/16![Southwest logo]()
$242
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:32 pm -
Nonstop3h 27m
Sun 11/16:30 am -
1 stop27h 34m
Deal found 9/16![Frontier logo]()
$243
This Cheapflightsfares deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:32 pm -
Nonstop3h 27m
Sun 10/254:20 pm -
Nonstop4h 07m
Deal found 9/12![Frontier logo]()
$244
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:35 am -
Nonstop3h 10m
Tue 12/16:05 am -
1 stop6h 10m
Deal found 9/14![Southwest logo]()
$244
This Alaska Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:45 pm -
1 stop9h 14m
Mon 11/22:15 pm -
1 stop10h 12m
Deal found 9/14![Alaska Airlines logo]()
$245
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:55 pm -
Nonstop3h 20m
Thu 10/226:00 pm -
1 stop5h 20m
Deal found 9/15![Southwest logo]()
$245
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:32 pm -
Nonstop3h 27m
Sun 10/186:30 am -
1 stop27h 40m
Deal found 9/13![Frontier logo]()
$246
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:55 pm -
Nonstop3h 20m
Wed 10/146:05 am -
1 stop6h 10m
Deal found 9/14![Southwest logo]()
$246
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
Nonstop3h 30m
Wed 11/256:40 am -
1 stop27h 05m
Deal found 9/15![Frontier logo]()
$247
Best flights from Mesa to ChicagoDiscover carefully curated flight deals from Mesa to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Mesa to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:55 pm -
Nonstop3h 20m
Thu 10/2210:55 pm -
Nonstop3h 50m
Deal found 9/16![Southwest logo]()
$265
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:05 am -
1 stop7h 42m
Mon 11/21:27 pm -
1 stop7h 51m
Deal found 9/15![Delta logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:21 pm -
1 stop23h 41m
Sun 11/158:37 pm -
1 stop17h 53m
Deal found 9/16![Multiple Airlines logo]()
$293
This Alaska Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:02 am -
1 stop8h 18m
Sat 10/319:00 am -
1 stop9h 34m
Deal found 9/12![Alaska Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:00 am -
Nonstop3h 39m
Tue 12/18:30 pm -
Nonstop4h 04m
Deal found 9/12![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:35 am -
Nonstop3h 10m
Sat 12/56:25 pm -
Nonstop3h 55m
Deal found 9/16![Southwest logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:30 am -
1 stop10h 32m
Sun 11/158:37 pm -
1 stop17h 53m
Deal found 9/15![Multiple Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:25 pm -
Nonstop3h 20m
Sun 11/19:45 pm -
Nonstop3h 50m
Deal found 9/16![Southwest logo]()
$287
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2011:35 pm -
1 stop9h 07m
Mon 11/235:13 pm -
1 stop7h 13m
Deal found 9/15![Delta logo]()
$321
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:00 am -
Nonstop3h 44m
Mon 10/262:00 pm -
1 stop8h 25m
Deal found 9/15![United Airlines logo]()
$330
This Alaska Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:22 pm -
1 stop15h 55m
Sun 11/157:57 pm -
1 stop15h 44m
Deal found 9/14![Alaska Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:20 pm -
1 stop20h 53m
Sun 10/189:33 pm -
1 stop23h 00m
Deal found 9/14![Multiple Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:30 pm -
1 stop5h 16m
Tue 10/203:40 pm -
Nonstop3h 55m
Deal found 9/14![United Airlines logo]()
$335
This Alaska Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:25 pm -
1 stop16h 00m
Sun 10/256:00 am -
1 stop8h 45m
Deal found 9/15![Alaska Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:05 am -
1 stop7h 07m
Tue 12/15:30 pm -
1 stop7h 59m
Deal found 9/12![Delta logo]()
$366
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3011:20 am -
Nonstop3h 40m
Mon 11/212:55 pm -
Nonstop4h 02m
Deal found 9/15![United Airlines logo]()
$340
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:55 pm -
Nonstop3h 20m
Sun 10/117:20 am -
Nonstop3h 55m
Deal found 9/16![Southwest logo]()
$372
This Alaska Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:25 pm -
1 stop16h 00m
Tue 10/137:00 am -
2 stops15h 41m
Deal found 9/15![Alaska Airlines logo]()
$397
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:16 am -
1 stop9h 14m
Sun 10/258:53 pm -
1 stop17h 24m
Deal found 9/16![Multiple Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:35 am -
Nonstop3h 10m
Wed 10/143:35 pm -
Nonstop3h 45m
Deal found 9/16![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:24 am -
Nonstop3h 36m
Tue 10/208:30 pm -
Nonstop3h 54m
Deal found 9/13![United Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:59 pm -
2 stops21h 03m
Sun 11/88:37 pm -
1 stop17h 53m
Deal found 9/14![Multiple Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:45 pm -
1 stop5h 55m
Mon 10/127:15 pm -
Nonstop3h 45m
Deal found 9/15![Southwest logo]()
$392
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:00 am -
Nonstop3h 38m
Mon 10/128:30 pm -
Nonstop3h 54m
Deal found 9/11![United Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:37 am -
2 stops23h 03m
Sun 10/49:36 pm -
1 stop20h 42m
Deal found 9/15![Multiple Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:35 am -
Nonstop3h 10m
Fri 10/95:40 am -
Nonstop3h 45m
Deal found 9/16![Southwest logo]()
$401
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:49 pm -
Nonstop3h 39m
Mon 10/128:30 pm -
Nonstop3h 54m
Deal found 9/11![United Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:16 am -
1 stop9h 57m
Sun 10/189:33 pm -
1 stop27h 45m
Deal found 9/13![Multiple Airlines logo]()
$428
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:40 am -
Nonstop3h 15m
Tue 10/136:05 am -
1 stop6h 10m
Deal found 9/15![Southwest logo]()
$401
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:49 pm -
Nonstop3h 39m
Wed 10/142:00 pm -
1 stop8h 49m
Deal found 9/11![United Airlines logo]()
$419
Last-minute flights from Mesa to ChicagoDiscover last-minute flight deals from Mesa to Chicago. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Chicago. Data last updated September 17, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:32 pm -
Nonstop3h 27m
Mon 10/123:30 pm -
1 stop25h 59m
Deal found 9/11![Frontier logo]()
$183
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:32 pm -
Nonstop3h 27m
Thu 10/158:01 pm -
1 stop22h 16m
Deal found 9/13![Frontier logo]()
$205
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:55 pm -
Nonstop3h 20m
Wed 10/146:05 am -
1 stop6h 10m
Deal found 9/14![Southwest logo]()
$246
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:52 pm -
Nonstop3h 28m
Tue 10/135:00 am -
1 stop6h 07m
Deal found 9/16![United Airlines logo]()
$247
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:32 pm -
Nonstop3h 27m
Sun 10/186:30 am -
1 stop27h 40m
Deal found 9/13![Frontier logo]()
$246
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:55 pm -
Nonstop3h 20m
Thu 10/226:00 pm -
1 stop5h 20m
Deal found 9/15![Southwest logo]()
$245
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:45 pm -
1 stop5h 55m
Mon 10/267:15 pm -
Nonstop3h 45m
Deal found 9/16![Southwest logo]()
$241
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:29 pm -
1 stop6h 55m
Thu 10/224:20 pm -
Nonstop4h 07m
Deal found 9/16![Frontier logo]()
$242
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:32 pm -
Nonstop3h 27m
Sun 11/16:30 am -
1 stop27h 34m
Deal found 9/16![Frontier logo]()
$243
This Cheapflightsfares deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:32 pm -
Nonstop3h 27m
Sun 10/254:20 pm -
Nonstop4h 07m
Deal found 9/12![Frontier logo]()
$244
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:45 pm -
1 stop5h 55m
Tue 10/276:55 am -
Nonstop3h 50m
Deal found 9/16![Southwest logo]()
$242
This Alaska Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:45 pm -
1 stop9h 14m
Mon 11/22:15 pm -
1 stop10h 12m
Deal found 9/14![Alaska Airlines logo]()
$245
One-way flights from Mesa to ChicagoSearch for one-way flight options from Mesa to Chicago. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Mesa to Chicago. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:21 am -
2 stops20h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$127
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2111:33 am -
1 stop8h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$128
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:50 am -
1 stop5h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$128
This Cheapflightsfares deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:59 pm -
1 stop25h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:32 pm -
Nonstop3h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Frontier logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:32 pm -
Nonstop3h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Frontier logo]()
$131
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:59 pm -
1 stop25h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Frontier logo]()
$132
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:33 pm -
Nonstop3h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$133
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:55 pm -
Nonstop3h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:21 am -
2 stops20h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:21 pm -
2 stops15h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Frontier logo]()
$134
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:04 pm -
Nonstop3h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$136
Find flight deals from Mesa to Chicago
Keep the following information in mind while searching for Mesa to Chicago flight deals. Data was last updated September 17, 2026.
Round-trip from | $205 (Cheapflightsfares) |
|---|---|
One-way from | $127 (Mytrip) |
Popular in | June |
Cheapest in | February |
Average price | $320 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Mesa to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixChicago
PHX Phoenix Sky Harbor Intl - ORD Chicago O'Hare Intl
PHXORD
Phoenix Sky Harbor Intl
Mon 11/16
11:35 pm-9:22 am
1 stop8h 47m
Chicago O'Hare Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$128
PhoenixChicago
PHX Phoenix Sky Harbor Intl - MDW Chicago Midway
PHXMDW
Phoenix Sky Harbor Intl
Mon 11/16
11:35 pm-9:42 am
1 stop9h 07m
Chicago Midway
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$128
PhoenixChicago
PHX Phoenix Sky Harbor Intl - MDW Chicago Midway
PHXMDW
Phoenix Sky Harbor Intl
Mon 10/19
6:55 pm-12:15 am
Nonstop3h 20m
Chicago Midway
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$133
Quickest round-trip
PhoenixChicago
PHX Phoenix Sky Harbor Intl - MDW Chicago Midway
PHXMDW
Phoenix Sky Harbor Intl
Fri 1/15
5:25 pm-9:40 pm
Nonstop3h 15m
Chicago Midway
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$133
PhoenixChicago
PHX Phoenix Sky Harbor Intl - MDW Chicago Midway
PHXMDW
Phoenix Sky Harbor Intl
Tue 10/6
5:25 pm-10:45 pm
Nonstop3h 20m
Chicago Midway
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$133
PhoenixChicago
PHX Phoenix Sky Harbor Intl - MDW Chicago Midway
PHXMDW
Phoenix Sky Harbor Intl
Thu 10/29
3:45 pm-9:00 pm
Nonstop3h 15m
Chicago Midway
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$133
PhoenixChicago
PHX Phoenix Sky Harbor Intl - ORD Chicago O'Hare Intl
PHXORD
Phoenix Sky Harbor Intl
Fri 1/15
2:20 pm-9:53 pm
1 stop6h 33m
Chicago O'Hare Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$143
PhoenixChicago
PHX Phoenix Sky Harbor Intl - MDW Chicago Midway
PHXMDW
Phoenix Sky Harbor Intl
Fri 11/13
3:00 pm-10:54 pm
1 stop6h 54m
Chicago Midway
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$143
PhoenixChicago
PHX Phoenix Sky Harbor Intl - MDW Chicago Midway
PHXMDW
Phoenix Sky Harbor Intl
Fri 10/9
5:05 pm-12:30 am
1 stop5h 25m
Chicago Midway
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$160
PhoenixChicago
PHX Phoenix Sky Harbor Intl - ORD Chicago O'Hare Intl
PHXORD
Phoenix Sky Harbor Intl
Sat 12/26
7:00 am-11:31 am
Nonstop3h 31m
Chicago O'Hare Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$163
Showing 1-10 of 59 resultsSorted by cheapest first
Best time to book a flight from Mesa to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Mesa with our price prediction graph.
PHX-ORD
PHX-MDW
PHX-RFD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Chicago
MS9-CHI
PHX-ORD
PHX-MDW
PHX-RFD
What is the cheapest time of day to fly from MS9 to CHI?
Find hourly flight availability from Mesa to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 19% on flights from Mesa to Chicago by exploring options for tickets in the afternoon.
Weekly flight availability from Mesa to Chicago
Explore weekly flight availability from Mesa to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2026.
The most flights from MS9 to CHI are scheduled on a Monday (67 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (54 on average).
How much does it cost to fly round-trip from Mesa to Chicago?
Airfare is below average for this route at the moment.
Mesa to Chicago flights typically cost between $265 and $383 in October.The cheapest round-trip price found within the last 5 days was $205 on Frontier (Oct 9-Oct 15).
What is the cheapest day to fly from Mesa to Chicago?
Use this chart to determine the cheapest time to fly round-trip from Mesa to Chicago. Price data was last updated on September 12, 2026.
Travelers seeking maximum savings on their Mesa to Chicago flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated September 17, 2026.
Read through reviews of airlines operating flights from Mesa to Chicago, such as Southwest,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Mesa to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Lansing
Merrillville
Valparaiso
Hammond
Saint Joseph
Porter
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Chicago flight routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Mesa to Chicago
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Complete your trip
Complete your trip to Chicago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mesa to Chicago by cabin class
Find flights from Mesa to Chicago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mesa and Chicago flights
Browse other Mesa and Chicago flight options. Last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Mesa to Chicago flights
Consider these flights traveling from Mesa to Chicago.
Top 7 airlines flying from Mesa to Chicago
Discover the top 7 airlines that operate flights from Mesa to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$58 | Average$200 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$118 | Average$293 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$142 | Average$202 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$173 | Average$259 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$187 | Average$350 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$193 | Average$337 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$198 | Average$382 | FlexibilityNo cancel fee | On-time71% |