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Cheap flights from Mesa, AZ to Chicago (CHI)

PHX — CHI
Dec 4 — Dec 111
Fri 12/4
Fri 12/11
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to Chicago are usually found in February or January, booked 58 days in advance, depart on a Thursday or Friday and return on a Saturday

Find flight deals from Mesa to Chicago

Popular in

June

Cheapest in

February

Average price

$338
Highest demand for flights based on searches. 10% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in November 2026
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Cheapflights Insights

Everything you need to know about your flight from Mesa to Chicago

What is the cheapest time of day to fly from MS9 to CHI?

Unlike in the evening, when flights are generally more expensive, you can save up to 19% on flights from Mesa to Chicago by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Mesa to Chicago?

Travelers seeking maximum savings on their Mesa to Chicago flight should consider departing on Saturday mornings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Chicago

Read through reviews of airlines operating flights from Mesa to Chicago, such as Southwest,United Airlines, andJetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,212 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
Southwest
8.0
Very good
4,212 reviews
Southwest
8.0
Very good
4,212 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
United Airlines
7.3
Good
10,460 reviews
Southwest
8.0
Very good
4,212 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
JetBlue
7.1
Good
3,065 reviews
Southwest
8.0
Very good
4,212 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
American Airlines
7.0
Good
12,230 reviews
Southwest
8.0
Very good
4,212 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
Frontier
5.5
Fair
2,511 reviews
Southwest
8.0
Very good
4,212 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Related info for your journey

  • What are the cheapest airlines to fly from Mesa to Chicago one-way?

    One-way options have recently been found by users for as low as $33 on Frontier. Other airlines that offer cheap prices include Delta from $108 and Southwest from $108 one-way.

  • What are the most popular routes from Mesa to Chicago?

    The most popular route from Mesa to Chicago is Phoenix Sky Harbor Intl - Chicago O'Hare Intl. You may also consider Phoenix Sky Harbor Intl - Chicago Midway or Phoenix Sky Harbor Intl - Chicago Greater Rockford.

  • What are the most reliable airlines from Mesa to Chicago?

    The top 3 most reliable airlines when flying from Mesa to Chicago are STARLUX Airlines (92%), Frontier (91%) and Volaris (91%).

  • What are the cheapest flights from Mesa to Chicago?

    Looking at all options, your cheapest flight can be booked for $109. While the most popular route (Phoenix Sky Harbor Intl - Chicago O'Hare Intl) can be booked for $229 on average, our data indicates $1,046 when flying from Mesa to Chicago.

  • Can I find deals for flights from Mesa to Chicago that include hotel bookings?

    Yes. In addition to deals on Mesa to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Chicago.

  • Can I find deals for business class flights from Mesa to Chicago?

    Yes. Cheapflights offers flight deals from Mesa to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Benton Harbor
Merrillville
Lansing
Valparaiso
Hammond
Saint Joseph
Porter

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Mesa to Chicago

AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$57Average$215FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$142Average$219FlexibilityNo cancel feeOn-time88%
JetBlueCheapest$173Average$288FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$187Average$360FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$193Average$347FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$215Average$383FlexibilityNo cancel feeOn-time71%

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