$123+ Cheap flights from Mesa, AZ to Charleston (CHS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — CHS
Aug 12 — Aug 191
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to Charleston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mesa to Charleston
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Cheapest flights from Mesa to CharlestonExplore the most affordable flight options available from Mesa to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
Explore the most affordable flight options available from Mesa to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:32 am
PHX
- CHS
1 stop7h 03m
United Airlines
Wed 9/27:00 am
CHS
- PHX
1 stop10h 13m
United Airlines
Deal found 7/8![United Airlines logo]()
$250
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:56 pm
PHX
- CHS
1 stop6h 02m
Delta
Sat 8/86:55 am
CHS
- PHX
1 stop9h 55m
Delta
Deal found 7/8![Delta logo]()
$255
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:45 am
PHX
- CHS
1 stop9h 14m
United Airlines
Tue 9/154:58 pm
CHS
- PHX
1 stop7h 31m
United Airlines
Deal found 7/9![United Airlines logo]()
$256
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:59 pm
PHX
- CHS
1 stop8h 22m
Delta
Tue 10/64:20 pm
CHS
- PHX
1 stop7h 42m
Delta
Deal found 7/8![Delta logo]()
$261
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:20 pm
PHX
- CHS
1 stop6h 55m
United Airlines
Fri 8/148:30 am
CHS
- PHX
1 stop6h 58m
United Airlines
Deal found 7/9![United Airlines logo]()
$262
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:10 am
PHX
- CHS
2 stops9h 00m
Southwest
Tue 8/256:45 am
CHS
- PHX
2 stops7h 15m
Southwest
Deal found 7/9![Southwest logo]()
$265
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:40 am
PHX
- CHS
2 stops7h 45m
Southwest
Tue 9/157:20 pm
CHS
- PHX
1 stop6h 00m
Southwest
Deal found 7/9![Southwest logo]()
$266
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:59 pm
PHX
- CHS
1 stop6h 33m
Delta
Fri 10/26:51 pm
CHS
- PHX
1 stop6h 51m
Delta
Deal found 7/10![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:00 am
PHX
- CHS
2 stops8h 45m
Southwest
Wed 8/197:35 am
CHS
- PHX
2 stops8h 25m
Southwest
Deal found 7/10![Southwest logo]()
$271
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:55 pm
PHX
- CHS
1 stop12h 25m
Southwest
Tue 10/136:40 am
CHS
- PHX
2 stops8h 10m
Southwest
Deal found 7/9![Southwest logo]()
$272
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:35 am
PHX
- CHS
2 stops7h 35m
Southwest
Sat 10/32:10 pm
CHS
- PHX
1 stop8h 20m
Southwest
Deal found 7/10![Southwest logo]()
$275
Best flights from Mesa to CharlestonDiscover carefully curated flight deals from Mesa to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
Discover carefully curated flight deals from Mesa to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:28 am
PHX
- CHS
1 stop7h 06m
United Airlines
Sat 9/127:00 am
CHS
- PHX
1 stop10h 13m
United Airlines
Deal found 7/8![United Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:00 am
PHX
- CHS
2 stops8h 45m
Southwest
Wed 8/197:35 am
CHS
- PHX
2 stops8h 25m
Southwest
Deal found 7/10![Southwest logo]()
$271
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:35 pm
PHX
- CHS
1 stop6h 09m
Delta
Sat 10/104:30 pm
CHS
- PHX
1 stop7h 32m
Delta
Deal found 7/9![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:20 am
PHX
- CHS
2 stops8h 20m
Southwest
Wed 12/96:35 am
CHS
- PHX
1 stop6h 10m
Southwest
Deal found 7/11![Southwest logo]()
$328
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:01 am
PHX
- CHS
1 stop7h 31m
United Airlines
Wed 9/97:00 am
CHS
- PHX
2 stops11h 20m
United Airlines
Deal found 7/10![United Airlines logo]()
$360
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:09 am
PHX
- CHS
1 stop7h 23m
United Airlines
Wed 8/2611:40 am
CHS
- PHX
2 stops11h 44m
United Airlines
Deal found 7/9![United Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:00 am
PHX
- CHS
2 stops8h 45m
Southwest
Sun 8/166:30 am
CHS
- PHX
2 stops9h 25m
Southwest
Deal found 7/10![Southwest logo]()
$399
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:15 pm
PHX
- CHS
1 stop6h 56m
United Airlines
Sun 8/166:30 am
CHS
- PHX
1 stop9h 26m
United Airlines
Deal found 7/10![United Airlines logo]()
$366
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:10 am
PHX
- CHS
1 stop7h 15m
Southwest
Sun 9/136:30 am
CHS
- PHX
2 stops8h 50m
Southwest
Deal found 7/9![Southwest logo]()
$405
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:48 am
PHX
- CHS
1 stop9h 11m
United Airlines
Sat 10/1011:36 am
CHS
- PHX
2 stops12h 13m
United Airlines
Deal found 7/8![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:47 pm
PHX
- CHS
2 stops11h 24m
United Airlines
Wed 8/1210:19 am
CHS
- PHX
2 stops15h 02m
United Airlines
Deal found 7/8![United Airlines logo]()
$409
Last-minute flights from Mesa to CharlestonDiscover last-minute flight deals from Mesa to Charleston. Data last updated July 13, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Charleston. Data last updated July 13, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:56 pm
PHX
- CHS
1 stop7h 24m
Delta
Fri 8/75:06 pm
CHS
- PHX
1 stop6h 50m
Delta
Deal found 7/8![Delta logo]()
$261
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:56 pm
PHX
- CHS
1 stop6h 02m
Delta
Sat 8/86:55 am
CHS
- PHX
1 stop9h 55m
Delta
Deal found 7/8![Delta logo]()
$255
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:59 pm
PHX
- CHS
2 stops10h 52m
United Airlines
Wed 8/127:00 am
CHS
- PHX
1 stop6h 22m
United Airlines
Deal found 7/8![United Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:19 pm
PHX
- CHS
1 stop7h 41m
American Airlines
Sat 8/82:06 pm
CHS
- PHX
1 stop6h 45m
American Airlines
Deal found 7/8![American Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:20 pm
PHX
- CHS
1 stop6h 55m
United Airlines
Fri 8/148:30 am
CHS
- PHX
1 stop6h 58m
United Airlines
Deal found 7/9![United Airlines logo]()
$262
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:00 am
PHX
- CHS
2 stops8h 45m
Southwest
Wed 8/197:35 am
CHS
- PHX
2 stops8h 25m
Southwest
Deal found 7/10![Southwest logo]()
$271
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:00 am
PHX
- CHS
2 stops7h 55m
Southwest
Mon 8/246:05 pm
CHS
- PHX
1 stop7h 15m
Southwest
Deal found 7/8![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:10 am
PHX
- CHS
2 stops9h 00m
Southwest
Tue 8/256:45 am
CHS
- PHX
2 stops7h 15m
Southwest
Deal found 7/9![Southwest logo]()
$265
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:35 am
PHX
- CHS
2 stops9h 00m
Southwest
Wed 9/26:45 am
CHS
- PHX
2 stops9h 55m
Southwest
Deal found 7/8![Southwest logo]()
$285
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:32 am
PHX
- CHS
1 stop7h 03m
United Airlines
Wed 9/27:00 am
CHS
- PHX
1 stop10h 13m
United Airlines
Deal found 7/8![United Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:20 am
PHX
- CHS
2 stops8h 25m
Southwest
Sat 9/511:00 am
CHS
- PHX
2 stops8h 30m
Southwest
Deal found 7/10![Southwest logo]()
$286
One-way flights from Mesa to CharlestonSearch for one-way flight options from Mesa to Charleston. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
Search for one-way flight options from Mesa to Charleston. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:45 am
PHX
- CHS
1 stop9h 14m
United Airlines
Deal found 7/10![United Airlines logo]()
$123
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:16 pm
PHX
- CHS
1 stop5h 41m
Delta
Deal found 7/8![Delta logo]()
$128
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:20 am
PHX
- CHS
2 stops8h 25m
Southwest
Deal found 7/10![Southwest logo]()
$133
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:59 pm
PHX
- CHS
1 stop6h 33m
Delta
Deal found 7/10![Delta logo]()
$134
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:43 pm
PHX
- CHS
2 stops11h 26m
United Airlines
Deal found 7/8![United Airlines logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/159:50 pm
PHX
- CHS
2 stops16h 47m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:15 pm
PHX
- CHS
3 stops39h 23m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$146
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:35 am
PHX
- CHS
2 stops9h 05m
Southwest
Deal found 7/8![Southwest logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:30 pm
PHX
- CHS
2 stops33h 21m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$158
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:37 pm
PHX
- CHS
1 stop9h 15m
American Airlines
Deal found 7/11![American Airlines logo]()
$162
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:30 am
PHX
- CHS
2 stops11h 51m
United Airlines
Deal found 7/9![United Airlines logo]()
$171
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:48 am
PHX
- CHS
1 stop9h 11m
United Airlines
Deal found 7/10![United Airlines logo]()
$173
Find flight deals from Mesa to Charleston
Keep the following information in mind while searching for Mesa to Charleston flight deals. Data was last updated July 13, 2026.
Round-trip from | $250 (United Airlines) |
|---|---|
One-way from | $123 (United Airlines) |
Popular in | August |
Cheapest in | February |
Average price | $431 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
Use the filters below to find and compare flights from Mesa to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Sat 9/5
11:28 am-9:34 pm
1 stop7h 06m
Charleston
Sat 9/12
7:00 am-2:13 pm
1 stop10h 13m
$250
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Wed 8/12
8:00 am-7:45 pm
2 stops8h 45m
Charleston
Wed 8/19
7:35 am-1:00 pm
2 stops8h 25m
$271
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Sat 12/5
6:20 am-4:40 pm
2 stops8h 20m
Charleston
Wed 12/9
6:35 am-10:45 am
1 stop6h 10m
$328
Quickest round-trip
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Tue 10/6
11:35 pm-8:44 am
1 stop6h 09m
Charleston
Sat 10/10
4:30 pm-9:02 pm
1 stop7h 32m
$347
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Wed 9/2
6:01 am-4:32 pm
1 stop7h 31m
Charleston
Wed 9/9
7:00 am-3:20 pm
2 stops11h 20m
$360
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Tue 8/25
6:09 am-4:32 pm
1 stop7h 23m
Charleston
Wed 8/26
11:40 am-8:24 pm
2 stops11h 44m
$360
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Thu 8/13
12:15 pm-10:11 pm
1 stop6h 56m
Charleston
Sun 8/16
6:30 am-12:56 pm
1 stop9h 26m
$366
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Wed 8/12
8:00 am-7:45 pm
2 stops8h 45m
Charleston
Sun 8/16
6:30 am-12:55 pm
2 stops9h 25m
$399
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Tue 10/6
11:48 am-11:59 pm
1 stop9h 11m
Charleston
Sat 10/10
11:36 am-8:49 pm
2 stops12h 13m
$399
PhoenixCharleston
PHX - CHS
PHXCHS
Phoenix Sky Harbor Intl
Fri 9/11
7:10 am-5:25 pm
1 stop7h 15m
Charleston
Sun 9/13
6:30 am-12:20 pm
2 stops8h 50m
$405
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Mesa to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Mesa with our price prediction graph.
PHX-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Charleston
MS9-CHS
PHX-CHS
How much does it cost to fly round-trip from Mesa to Charleston?
Reviews of airlines servicing Charleston
Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated July 13, 2026.
Read through reviews of airlines operating flights from Mesa to Charleston, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Mesa to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach
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Alternative routes for Mesa to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 13, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mesa to Charleston by cabin class
Find flights from Mesa to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mesa and Charleston flights
Browse other Mesa and Charleston flight options. Last updated on July 13, 2026.
Popular flight searches
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Mesa to Charleston flights
Consider these flights traveling from Mesa to Charleston.
Top 4 airlines flying from Mesa to Charleston
Discover the top 4 airlines that operate flights from Mesa to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$242 | Average$380 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$242 | Average$418 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$243 | Average$400 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$270 | Average$352 | FlexibilityNo cancel fee | On-time69% |