It’s generally more expensive to depart on a Friday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.
Due to multiple factors, expect to potentially pay more when booking in March. For low rates, August can be a great choice for travel to Charlottesville. Flights to Charlottesville from Greenville in August are about $374 on average during August, but can be found for as low as $217.
A simple way to save on the total cost of your ticket is to fly from Greenville to Charlottesville at noon. If you’re flexible enough to do this you can expect to save up to 28% on your trip compared to booking a flight in the morning.