$317+ Cheap flights from Wilkes-Barre, PA to the Cayman Islands
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — GCM
Jan 20 — Jan 271
1 adult, Economy
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Cheapest flights from Wilkes-Barre to Cayman IslandsExplore the most affordable flight options available from Wilkes-Barre to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 21, 2025.
Explore the most affordable flight options available from Wilkes-Barre to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 21, 2025.
This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:21 pmAVP - GCM
2 stops18h 26mAmerican Airlines
Tue 1/138:50 amGCM - AVP
2 stops11h 08mAmerican Airlines
Deal found 12/20![American Airlines logo]()
$317
Find flight deals from Wilkes-Barre to Cayman Islands
Keep the following information in mind while searching for Wilkes-Barre to Cayman Islands flight deals. Data was last updated December 21, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $411 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Wilkes-Barre to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Wilkes-Barre to the Cayman Islands that are best for you.
Fly from
Wilkes-Barre
Fly to
Cayman Islands
Route
Depart
Return
Price
ScrantonGeorge Town
AVP - GCM
AVPGCM
Wilkes-Barre Scranton
Sun 1/25
7:45 pm-1:15 pm
2 stops17h 30m
George Town Owen Roberts Intl
Thu 1/29
2:25 pm-9:47 am
2 stops19h 22m
$411
ScrantonGeorge Town
AVP - GCM
AVPGCM
Wilkes-Barre Scranton
Mon 2/2
7:45 pm-1:15 pm
2 stops17h 30m
George Town Owen Roberts Intl
Mon 2/9
2:25 pm-9:47 am
2 stops19h 22m
$411
ScrantonGeorge Town
AVP - GCM
AVPGCM
Wilkes-Barre Scranton
Tue 1/6
7:45 pm-1:15 pm
2 stops17h 30m
George Town Owen Roberts Intl
Thu 1/8
2:50 pm-6:45 pm
2 stops51h 55m
$456
Best time to book a flight from Wilkes-Barre to Cayman Islands
Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
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Cheapflights Insights
Everything you need to know about your flight from Wilkes-Barre to the Cayman Islands
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Related info for your journey
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Alternative routes for Wilkes-Barre to Cayman Islands
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Top airline flying from Wilkes-Barre to Cayman Islands
Discover the top airline that operate flights from Wilkes-Barre to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$421 | Average$629 | FlexibilityNo cancel fee | On-time71% |