HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cayman Islands

$376+ Cheap flights from Iowa to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GCM
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Iowa to Cayman Islands with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to Cayman Islands

Cheapest flights from Iowa to Cayman Islands
Explore the most affordable flight options available from Iowa to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amOMA - GCM
1 stop6h 27mDelta
Tue 12/301:52 pmGCM - OMA
1 stop8h 19mDelta
Deal found 12/17$406
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:15 amOMA - GCM
1 stop6h 45mUnited Airlines
Tue 12/302:50 pmGCM - OMA
1 stop8h 08mUnited Airlines
Deal found 12/16$486
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/168:15 amDSM - GCM
1 stop7h 15mUnited Airlines
Sun 12/212:50 pmGCM - DSM
1 stop7h 50mUnited Airlines
Deal found 12/15$526
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:08 pmDSM - GCM
2 stops25h 19mDelta
Wed 12/241:52 pmGCM - DSM
2 stops22h 36mDelta
Deal found 12/16$531
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/163:38 pmDSM - GCM
2 stops19h 46mAmerican Airlines
Sun 12/2112:50 pmGCM - DSM
2 stops12h 47mAmerican Airlines
Deal found 12/15$536
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:00 amDSM - GCM
1 stop9h 00mUnited Airlines
Wed 12/242:50 pmGCM - DSM
1 stop7h 50mUnited Airlines
Deal found 12/17$636
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:52 pmDSM - GCM
1 stop18h 43mAmerican Airlines
Mon 1/57:30 amGCM - DSM
1 stop17h 18mAmerican Airlines
Deal found 12/15$715
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:08 pmDSM - GCM
2 stops25h 19mDelta
Thu 12/253:42 pmGCM - DSM
2 stops19h 07mDelta
Deal found 12/16$721

Find flight deals from Iowa to Cayman Islands

Keep the following information in mind while searching for Iowa to Cayman Islands flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$376
(American Airlines)

Popular in

February

Cheapest in

November

Average price

$947
Provider with most accurate pricing for Des Moines-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-George Town Owen Roberts Intl flights.
Search Deals
From Iowa to Cayman Islands
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($130 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Iowa to the Cayman Islands that are best for you.

Fly from

Iowa

Fly to

Cayman Islands

Route

Depart

Return

Price

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Mon 1/26

5:04 pm-11:26 am

1 stop17h 22m

George Town Owen Roberts Intl

Thu 1/29

3:45 pm-11:59 pm

1 stop9h 14m

$376

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Mon 1/26

5:18 pm-1:15 pm

2 stops18h 57m

George Town Owen Roberts Intl

Thu 1/29

2:25 pm-10:30 am

2 stops21h 05m

$381

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Wed 2/4

6:10 am-8:20 pm

2 stops13h 10m

George Town Owen Roberts Intl

Wed 2/11

1:05 pm-11:59 pm

1 stop11h 54m

$381

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Thu 1/22

1:50 pm-1:15 pm

2 stops22h 25m

George Town Owen Roberts Intl

Wed 1/28

2:25 pm-12:44 pm

2 stops23h 19m

$381

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Fri 1/23

6:35 am-2:40 pm

1 stop7h 05m

George Town Owen Roberts Intl

Wed 1/28

2:05 pm-11:59 pm

1 stop10h 54m

$406

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Thu 1/22

5:30 am-12:40 pm

1 stop6h 10m

George Town Owen Roberts Intl

Wed 1/28

2:05 pm-11:59 pm

1 stop10h 54m

$406

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Fri 1/30

5:04 pm-11:26 am

1 stop17h 22m

George Town Owen Roberts Intl

Fri 2/6

8:50 am-11:59 pm

1 stop16h 09m

$406

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Sat 1/31

5:40 pm-2:45 pm

2 stops20h 05m

George Town Owen Roberts Intl

Sat 2/7

4:25 pm-11:33 pm

1 stop8h 08m

$411

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Fri 1/2

6:44 pm-4:55 pm

1 stop21h 11m

George Town Owen Roberts Intl

Sun 1/11

2:49 pm-10:19 am

2 stops20h 30m

$439

MolineGeorge Town

MLI - GCM

MLIGCM

Moline Quad-City

Tue 2/17

5:59 am-2:33 pm

1 stop7h 34m

George Town Owen Roberts Intl

Tue 2/24

4:25 pm-11:06 pm

1 stop7h 41m

$462

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 20 results
1
2

Best time to book a flight from Iowa to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to the Cayman Islands

What is the cheapest month to book a flight from Iowa to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from Iowa to Cayman Islands (average of $311). Flying from Iowa to Cayman Islands in May is currently the most expensive (average of $642). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to KY?

Find hourly flight availability from Iowa to Cayman Islands. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 20% on flights from Iowa to Cayman Islands by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Cayman Islands?

    There are many flights that can get you from Iowa to Cayman Islands in 6h 05m. Fly via American Airlines, United Airlines, or Delta to get the fastest option. There are 1697 mi between Iowa and Cayman Islands. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Iowa to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Iowa to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Cayman Islands.

  • Can I find deals for business class flights from Iowa to Cayman Islands?

    Yes. Cheapflights offers flight deals from Iowa to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Cayman Islands (average of $311). Flying from Iowa to Cayman Islands in May is currently the most expensive (average of $642). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Luis Munoz Marin Intl flights
Newark to Luis Munoz Marin Intl flights
John F Kennedy Intl to Santiago de los Caballeros flights
John F Kennedy Intl to Santo Domingo flights
LaGuardia to Luis Munoz Marin Intl flights
O'Hare Intl to Luis Munoz Marin Intl flights
John F Kennedy Intl to Punta Cana flights
Dulles Intl to Luis Munoz Marin Intl flights
Newark to Santo Domingo flights
Newark to Punta Cana flights
Philadelphia to Luis Munoz Marin Intl flights
Orlando to Luis Munoz Marin Intl flights
Boston to Luis Munoz Marin Intl flights
Newark to Santiago de los Caballeros flights
Baltimore to Luis Munoz Marin Intl flights
Reagan-National to Luis Munoz Marin Intl flights
Newark to Oranjestad flights
John F Kennedy Intl to Oranjestad flights
Dallas/Fort Worth to Luis Munoz Marin Intl flights
Atlanta to Luis Munoz Marin Intl flights
Hartford to Luis Munoz Marin Intl flights
John F Kennedy Intl to Port of Spain flights
LaGuardia to Punta Cana flights
John F Kennedy Intl to Montego Bay flights
Tampa to Luis Munoz Marin Intl flights
LaGuardia to Santo Domingo flights
Boston to Oranjestad flights
Newark to Simpson Bay flights
Boston to Santo Domingo flights
Raleigh to Luis Munoz Marin Intl flights
O'Hare Intl to Punta Cana flights
John F Kennedy Intl to Simpson Bay flights
Newark to Nassau flights
Detroit to Luis Munoz Marin Intl flights
Dulles Intl to Punta Cana flights
Boston to Punta Cana flights
Minneapolis to Luis Munoz Marin Intl flights
Fort Lauderdale to Luis Munoz Marin Intl flights
Orlando to Punta Cana flights
Hobby to Luis Munoz Marin Intl flights
Newark to Montego Bay flights
Midway to Luis Munoz Marin Intl flights
John F Kennedy Intl to Kingston flights
John F Kennedy Intl to Nassau flights
LaGuardia to Oranjestad flights
Newark to Saint Thomas Island flights
John F Kennedy Intl to Providenciales flights
John F Kennedy Intl to Saint Thomas Island flights
Miami to Santo Domingo flights
Fort Lauderdale to Santo Domingo flights

Top 3 airlines flying from Iowa to Cayman Islands

Discover the top 3 airlines that operate flights from Iowa to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$496Average$605FlexibilityNo cancel feeOn-time69%
DeltaCheapest$534Average$711FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$547Average$652FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.