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Cayman Islands

$263+ Cheap flights from Iowa to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GCM
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Iowa to Cayman Islands

Cheapest flights from Iowa to Cayman Islands
Explore the most affordable flight options available from Iowa to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:55 am
MLI
-
GCM
1 stop5h 34m
Delta
Tue 3/101:12 pm
GCM
-
MLI
1 stop9h 18m
Delta
Deal found 1/28$359
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:00 am
MLI
-
GCM
1 stop7h 35m
American Airlines
Tue 3/1012:05 pm
GCM
-
MLI
2 stops11h 32m
American Airlines
Deal found 1/27$415
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:42 pm
OMA
-
GCM
1 stop18h 03m
United Airlines
Wed 3/184:45 pm
GCM
-
OMA
2 stops21h 39m
United Airlines
Deal found 1/27$433
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:15 am
OMA
-
GCM
1 stop6h 15m
United Airlines
Sun 5/171:35 pm
GCM
-
OMA
1 stop8h 54m
United Airlines
Deal found 1/28$464
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:42 pm
OMA
-
GCM
1 stop18h 03m
United Airlines
Mon 3/164:45 pm
GCM
-
OMA
2 stops17h 49m
United Airlines
Deal found 1/28$488
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:10 am
OMA
-
GCM
1 stop9h 15m
American Airlines
Mon 2/233:45 pm
GCM
-
OMA
1 stop9h 14m
American Airlines
Deal found 1/28$494
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/95:04 pm
OMA
-
GCM
1 stop17h 22m
American Airlines
Sun 2/154:25 pm
GCM
-
OMA
1 stop17h 32m
American Airlines
Deal found 1/28$504
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/223:22 pm
OMA
-
GCM
1 stop21h 23m
United Airlines
Thu 2/262:50 pm
GCM
-
OMA
1 stop8h 09m
United Airlines
Deal found 1/28$512
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:17 pm
OMA
-
GCM
2 stops17h 23m
American Airlines
Wed 3/187:45 am
GCM
-
OMA
2 stops16h 30m
American Airlines
Deal found 1/27$515
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:00 am
DSM
-
GCM
1 stop6h 30m
American Airlines
Tue 4/712:00 pm
GCM
-
DSM
2 stops23h 26m
American Airlines
Deal found 1/27$560
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/234:24 pm
MLI
-
GCM
2 stops18h 26m
American Airlines
Wed 9/3012:35 pm
GCM
-
MLI
1 stop9h 04m
American Airlines
Deal found 1/27$564
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:02 pm
DSM
-
GCM
2 stops20h 58m
American Airlines
Thu 4/302:10 pm
GCM
-
DSM
2 stops23h 01m
American Airlines
Deal found 1/27$590

Find flight deals from Iowa to Cayman Islands

Keep the following information in mind while searching for Iowa to Cayman Islands flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(Delta)

One-way from

$263
(United Airlines)

Popular in

February

Cheapest in

November

Average price

$750
Provider with most accurate pricing for Des Moines-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-George Town Owen Roberts Intl flights.
Search Deals
From Iowa to Cayman Islands
Search Deals
One-way flight from Iowa to Cayman Islands
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($113 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Iowa to the Cayman Islands that are best for you.

Fly from

Iowa

Fly to

Cayman Islands

Route

Depart

Return

Price

MolineGeorge Town

MLI - GCM

MLIGCM

Moline Quad-City

Mon 3/2

5:55 am-12:29 pm

1 stop5h 34m

George Town Owen Roberts Intl

Tue 3/10

1:12 pm-10:30 pm

1 stop9h 18m

$359

MolineGeorge Town

MLI - GCM

MLIGCM

Moline Quad-City

Mon 3/2

7:00 am-8:15 pm

2 stops12h 15m

George Town Owen Roberts Intl

Tue 3/10

7:45 am-8:59 pm

2 stops13h 14m

$415

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Wed 3/11

6:42 pm-12:45 pm

1 stop18h 03m

George Town Owen Roberts Intl

Wed 3/18

4:45 pm-2:24 pm

2 stops21h 39m

$433

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Thu 3/19

7:00 am-1:44 pm

1 stop6h 44m

George Town Owen Roberts Intl

Mon 3/23

3:30 pm-8:57 am

1 stop17h 27m

$491

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Thu 3/12

5:25 pm-12:15 pm

2 stops18h 50m

George Town Owen Roberts Intl

Mon 3/16

1:25 pm-10:34 am

2 stops21h 09m

$496

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Sun 2/22

3:22 pm-1:45 pm

1 stop21h 23m

George Town Owen Roberts Intl

Thu 2/26

2:50 pm-9:59 pm

1 stop8h 09m

$512

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Wed 3/11

5:17 pm-10:40 am

2 stops17h 23m

George Town Owen Roberts Intl

Wed 3/18

7:45 am-12:15 am

2 stops16h 30m

$515

OmahaGeorge Town

OMA - GCM

OMAGCM

Omaha Eppley Airfield

Thu 3/19

5:25 pm-12:15 pm

2 stops18h 50m

George Town Owen Roberts Intl

Mon 3/23

4:45 pm-12:45 pm

2 stops20h 00m

$530

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Tue 3/31

7:00 am-1:30 pm

1 stop6h 30m

George Town Owen Roberts Intl

Tue 4/7

12:00 pm-11:26 am

2 stops23h 26m

$560

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Thu 4/23

2:02 pm-11:00 am

2 stops20h 58m

George Town Owen Roberts Intl

Thu 4/30

12:35 pm-1:11 pm

1 stop24h 36m

$601

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 20 results
1
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Best time to book a flight from Iowa to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to the Cayman Islands

What is the cheapest month to book a flight from Iowa to Cayman Islands?

Currently, April is the cheapest month in which you can book a flight from Iowa to Cayman Islands (average of $199). Flying from Iowa to Cayman Islands in May is currently the most expensive (average of $679). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Cayman Islands?

    There are many flights that can get you from Iowa to Cayman Islands in 5h 34m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. There are 1622 mi between Iowa and Cayman Islands. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Iowa to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Iowa to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Cayman Islands.

  • Can I find deals for business class flights from Iowa to Cayman Islands?

    Yes. Cheapflights offers flight deals from Iowa to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Cayman Islands?

    Currently, April is the cheapest month in which you can book a flight from Iowa to Cayman Islands (average of $199). Flying from Iowa to Cayman Islands in May is currently the most expensive (average of $679). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Cayman Islands

Discover the top 3 airlines that operate flights from Iowa to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$154Average$676FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$496Average$605FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$517Average$627FlexibilityNo cancel feeOn-time71%

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