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Cayman Islands

$96+ Cheap flights from Buffalo (BUF) to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from Buffalo to Cayman Islands

Cheapest flights from Buffalo to Cayman Islands
Explore the most affordable flight options available from Buffalo to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:19 am
BUF
-
GCM
1 stop7h 55m
American Airlines
Tue 2/243:35 pm
GCM
-
BUF
1 stop8h 05m
American Airlines
Deal found 2/3$313
This Priceline deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:00 am
BUF
-
GCM
1 stop8h 35m
JetBlue
Mon 3/92:40 pm
GCM
-
BUF
1 stop7h 52m
JetBlue
Deal found 2/3$332
This Justfly.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:00 am
BUF
-
GCM
1 stop8h 34m
JetBlue
Sat 2/283:40 pm
GCM
-
BUF
1 stop7h 52m
JetBlue
Deal found 2/2$356
This Justfly.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:00 am
BUF
-
GCM
1 stop8h 35m
JetBlue
Sat 2/283:40 pm
GCM
-
BUF
1 stop7h 52m
JetBlue
Deal found 2/2$377
This Justfly.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:00 am
BUF
-
GCM
1 stop8h 35m
JetBlue
Sat 2/283:40 pm
GCM
-
BUF
1 stop7h 52m
JetBlue
Deal found 2/2$402
This Justfly.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:00 am
BUF
-
GCM
1 stop8h 35m
JetBlue
Sun 3/13:40 pm
GCM
-
BUF
1 stop7h 52m
JetBlue
Deal found 2/2$423
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:54 am
BUF
-
GCM
2 stops8h 16m
American Airlines
Tue 7/142:10 pm
GCM
-
BUF
2 stops18h 26m
American Airlines
Deal found 2/3$433
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:30 pm
BUF
-
GCM
2 stops18h 15m
United Airlines
Mon 3/94:45 pm
GCM
-
BUF
2 stops19h 32m
United Airlines
Deal found 2/3$441
This Justfly.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:00 am
BUF
-
GCM
1 stop8h 35m
JetBlue
Sun 3/13:40 pm
GCM
-
BUF
1 stop7h 52m
JetBlue
Deal found 2/2$448
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:00 am
BUF
-
GCM
1 stop6h 45m
United Airlines
Wed 3/42:25 pm
GCM
-
BUF
2 stops33h 17m
United Airlines
Deal found 2/1$456
This Justfly.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:00 am
BUF
-
GCM
1 stop8h 34m
JetBlue
Mon 3/23:40 pm
GCM
-
BUF
1 stop7h 52m
JetBlue
Deal found 2/2$466

Find flight deals from Buffalo to Cayman Islands

Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$313
(American Airlines)

One-way from

$96
(United Airlines)

Popular in

July

Cheapest in

May

Average price

$579
Provider with most accurate pricing for Buffalo-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-George Town Owen Roberts Intl flights.
Search Deals
From Buffalo to Cayman Islands
Search Deals
One-way flight from Buffalo to Cayman Islands
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.

Fly from

Buffalo

Fly to

Cayman Islands

Route

Depart

Return

Price

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Thu 2/19

6:19 am-2:14 pm

1 stop7h 55m

George Town Owen Roberts Intl

Tue 2/24

3:35 pm-11:40 pm

1 stop8h 05m

$313

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Fri 3/6

7:00 am-1:45 pm

1 stop6h 45m

George Town Owen Roberts Intl

Mon 3/9

1:25 pm-2:14 pm

2 stops23h 49m

$313

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Fri 3/6

6:00 am-2:35 pm

1 stop8h 35m

George Town Owen Roberts Intl

Mon 3/9

2:40 pm-11:32 pm

1 stop7h 52m

$332

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Mon 2/23

6:00 am-2:34 pm

1 stop8h 34m

George Town Owen Roberts Intl

Sat 2/28

3:40 pm-11:32 pm

1 stop7h 52m

$356

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Mon 2/23

6:00 am-2:34 pm

1 stop8h 34m

George Town Owen Roberts Intl

Sun 3/1

3:40 pm-11:32 pm

1 stop7h 52m

$402

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sat 2/21

6:00 am-2:35 pm

1 stop8h 35m

George Town Owen Roberts Intl

Sat 2/28

3:40 pm-11:32 pm

1 stop7h 52m

$402

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sun 2/22

6:00 am-2:35 pm

1 stop8h 35m

George Town Owen Roberts Intl

Sun 3/1

3:40 pm-11:32 pm

1 stop7h 52m

$423

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sat 7/11

6:05 am-11:00 am

1 stop5h 55m

George Town Owen Roberts Intl

Tue 7/21

2:10 pm-9:36 am

2 stops18h 26m

$433

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sun 4/19

7:00 am-12:45 pm

1 stop6h 45m

$96

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Mon 3/30

7:40 pm-10:40 am

1 stop16h 00m

$96

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 16 results
1
2

Best time to book a flight from Buffalo to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to the Cayman Islands
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated February 4, 2026.
Peruse reviews from past customers who have flown with American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,216 reviews

Food

6.4

Entertainment

6.9

Crew

8.0

Overall

7.2

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,216 reviews
American Airlines
7.2
Good
11,216 reviews

Food

6.4

Entertainment

6.9

Crew

8.0

Overall

7.2

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Cayman Islands?

    Located just 8.3 mi from the city center, Buffalo (BUF) is the airport most travelers will use when flying to Cayman Islands from Buffalo.

  • How long is the flight from Buffalo to Cayman Islands?

    A quick flight from Buffalo to Cayman Islands can take about 6h 45m. American Airlines provides one of the quickest options available for as low as $313. The distance between Buffalo and Cayman Islands is about 1640 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Buffalo to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Buffalo to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Cayman Islands.

  • Can I find deals for business class flights from Buffalo to Cayman Islands?

    Yes. Cheapflights offers flight deals from Buffalo to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Buffalo to Cayman Islands

Discover the top airline that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$339Average$550FlexibilityNo cancel feeOn-time71%

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