HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cayman Islands

$127+ Cheap flights from Buffalo (BUF) to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — GCM
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Buffalo to Cayman Islands with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Buffalo to Cayman Islands

Best flights from Buffalo to Cayman Islands
Discover carefully curated flight deals from Buffalo to Cayman Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/147:30 amBUF - GCM
1 stop7h 05mAmerican Airlines
Wed 1/213:30 pmGCM - BUF
1 stop8h 18mAmerican Airlines
Deal found 12/16$296
This JetBlue deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/67:00 amBUF - GCM
1 stop7h 35mJetBlue
Sun 2/83:40 pmGCM - BUF
1 stop8h 15mJetBlue
Deal found 12/17$314
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:00 amBUF - GCM
1 stop6h 40mDelta
Sat 2/72:15 pmGCM - BUF
1 stop10h 01mDelta
Deal found 12/17$320
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/316:32 pmBUF - GCM
2 stops17h 18mAmerican Airlines
Sat 2/73:45 pmGCM - BUF
2 stops19h 36mAmerican Airlines
Deal found 12/17$301
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:00 amBUF - GCM
1 stop6h 40mDelta
Fri 2/131:54 pmGCM - BUF
1 stop9h 37mDelta
Deal found 12/17$320
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/86:00 amBUF - GCM
1 stop6h 40mDelta
Thu 2/121:54 pmGCM - BUF
1 stop9h 37mDelta
Deal found 12/17$320
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/86:00 amBUF - GCM
1 stop6h 40mDelta
Fri 2/131:54 pmGCM - BUF
1 stop9h 37mDelta
Deal found 12/17$320
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:00 amBUF - GCM
1 stop6h 40mDelta
Fri 2/131:54 pmGCM - BUF
1 stop9h 37mDelta
Deal found 12/17$320
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/57:45 pmBUF - GCM
2 stops16h 55mDelta
Thu 2/121:54 pmGCM - BUF
1 stop9h 37mDelta
Deal found 12/17$325

Find flight deals from Buffalo to Cayman Islands

Keep the following information in mind while searching for Buffalo to Cayman Islands flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$296
(American Airlines)

One-way from

$127
(American Airlines)

Popular in

July

Cheapest in

January

Average price

$739
Provider with most accurate pricing for Buffalo-George Town Owen Roberts Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-George Town Owen Roberts Intl flights.
Search Deals
From Buffalo to Cayman Islands
Search Deals
One-way flight from Buffalo to Cayman Islands
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($45 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Buffalo to the Cayman Islands that are best for you.

Fly from

Buffalo

Fly to

Cayman Islands

Route

Depart

Return

Price

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Wed 1/14

7:30 am-2:35 pm

1 stop7h 05m

George Town Owen Roberts Intl

Wed 1/21

3:30 pm-11:48 pm

1 stop8h 18m

$296

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sat 1/31

6:32 pm-11:50 am

2 stops17h 18m

George Town Owen Roberts Intl

Sat 2/7

3:45 pm-11:21 am

2 stops19h 36m

$301

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Fri 2/6

7:00 am-2:35 pm

1 stop7h 35m

George Town Owen Roberts Intl

Sun 2/8

3:40 pm-11:55 pm

1 stop8h 15m

$314

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Fri 2/6

6:00 am-12:40 pm

1 stop6h 40m

George Town Owen Roberts Intl

Sat 2/7

2:15 pm-12:16 am

1 stop10h 01m

$320

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Mon 2/9

6:00 am-12:40 pm

1 stop6h 40m

George Town Owen Roberts Intl

Fri 2/13

1:54 pm-11:31 pm

1 stop9h 37m

$320

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sun 2/8

6:00 am-12:40 pm

1 stop6h 40m

George Town Owen Roberts Intl

Thu 2/12

1:54 pm-11:31 pm

1 stop9h 37m

$320

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Sun 2/8

6:00 am-12:40 pm

1 stop6h 40m

George Town Owen Roberts Intl

Fri 2/13

1:54 pm-11:31 pm

1 stop9h 37m

$320

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Fri 2/6

6:00 am-12:40 pm

1 stop6h 40m

George Town Owen Roberts Intl

Fri 2/13

1:54 pm-11:31 pm

1 stop9h 37m

$320

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Thu 2/5

7:45 pm-12:40 pm

2 stops16h 55m

George Town Owen Roberts Intl

Thu 2/12

1:54 pm-11:31 pm

1 stop9h 37m

$325

BuffaloGeorge Town

BUF - GCM

BUFGCM

Buffalo

Thu 1/15

6:53 pm-2:45 pm

2 stops19h 52m

$127

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 11 results
1
2

Best time to book a flight from Buffalo to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to the Cayman Islands
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated December 18, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Buffalo to the Cayman Islands to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Cayman Islands?

    Located just 8.3 mi from the city center, Buffalo (BUF) is the airport most travelers will use when flying to Cayman Islands from Buffalo.

  • How long is the flight from Buffalo to Cayman Islands?

    A quick flight from Buffalo to Cayman Islands can take about 7h 05m. American Airlines provides one of the quickest options available for as low as $296. The distance between Buffalo and Cayman Islands is about 1640 mi.

  • Can I find deals for flights from Buffalo to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Buffalo to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Cayman Islands.

  • Can I find deals for business class flights from Buffalo to Cayman Islands?

    Yes. Cheapflights offers flight deals from Buffalo to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Buffalo to Cayman Islands

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Luis Munoz Marin Intl flights
Newark to Luis Munoz Marin Intl flights
John F Kennedy Intl to Santiago de los Caballeros flights
John F Kennedy Intl to Santo Domingo flights
LaGuardia to Luis Munoz Marin Intl flights
John F Kennedy Intl to Punta Cana flights
Newark to Santo Domingo flights
Newark to Punta Cana flights
Newark to Santiago de los Caballeros flights
Newark to Oranjestad flights
John F Kennedy Intl to Oranjestad flights
John F Kennedy Intl to Port of Spain flights
LaGuardia to Punta Cana flights
John F Kennedy Intl to Montego Bay flights
LaGuardia to Santo Domingo flights
Newark to Simpson Bay flights
John F Kennedy Intl to Simpson Bay flights
Newark to Nassau flights
Newark to Montego Bay flights
John F Kennedy Intl to Kingston flights
John F Kennedy Intl to Nassau flights
LaGuardia to Oranjestad flights
Newark to Saint Thomas Island flights
John F Kennedy Intl to Providenciales flights
John F Kennedy Intl to Saint Thomas Island flights
Newark to Providenciales flights
John F Kennedy Intl to Willemstad flights
LaGuardia to Nassau flights
LaGuardia to Simpson Bay flights
LaGuardia to Santiago de los Caballeros flights
John F Kennedy Intl to Puerto Plata flights
LaGuardia to Montego Bay flights
John F Kennedy Intl to St. John's flights
LaGuardia to Providenciales flights
Newark to George Town flights
John F Kennedy Intl to Aguadilla flights
John F Kennedy Intl to Bridgetown flights
LaGuardia to Saint Thomas Island flights
John F Kennedy Intl to Castries flights
John F Kennedy Intl to George Town flights
Newark to Puerto Plata flights
LaGuardia to Port of Spain flights
Islip to Luis Munoz Marin Intl flights
White Plains to Luis Munoz Marin Intl flights
Newark to Kingston flights
John F Kennedy Intl to St. George's flights
LaGuardia to Willemstad flights
LaGuardia to Kingston flights
Newark to Bridgetown flights
LaGuardia to George Town flights

Top 2 airlines flying from Buffalo to Cayman Islands

Discover the top 2 airlines that operate flights from Buffalo to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$339Average$550FlexibilityNo cancel feeOn-time71%
DeltaCheapest$414Average$471FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.