$364+ Cheap flights from Missouri to Cape Cod and the Islands
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MVY
Mar 6 — Mar 131
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Cape Cod and the Islands
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to Cape Cod and the IslandsExplore the most affordable flight options available from Missouri to Cape Cod and the Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
Explore the most affordable flight options available from Missouri to Cape Cod and the Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:27 am
STL
- MVY
1 stop7h 39m
American Airlines
Sat 8/1511:59 am
MVY
- STL
1 stop5h 15m
American Airlines
Deal found 2/1![American Airlines logo]()
$616
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:56 pm
SGF
- ACK
2 stops16h 53m
American Airlines
Tue 7/1411:05 am
ACK
- SGF
2 stops12h 34m
American Airlines
Deal found 2/3![American Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:09 am
SGF
- ACK
2 stops8h 19m
American Airlines
Mon 7/2010:24 am
ACK
- SGF
2 stops12h 15m
American Airlines
Deal found 2/2![American Airlines logo]()
$705
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
SGF
- ACK
2 stops31h 47m
United Airlines
Sat 9/54:32 pm
ACK
- SGF
1 stop19h 02m
United Airlines
Deal found 2/1![United Airlines logo]()
$720
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/271:57 pm
JLN
- ACK
2 stops23h 54m
United Airlines
Thu 7/3010:18 am
ACK
- JLN
2 stops28h 03m
United Airlines
Deal found 1/31![United Airlines logo]()
$1,120
This Expedia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/162:47 pm
STL
- MVY
2 stops17h 27m
Multiple Airlines
Fri 2/207:09 am
MVY
- STL
2 stops17h 50m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$1,508
Best flights from Missouri to Cape Cod and the IslandsDiscover carefully curated flight deals from Missouri to Cape Cod and the Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
Discover carefully curated flight deals from Missouri to Cape Cod and the Islands that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:56 pm
SGF
- ACK
2 stops16h 53m
American Airlines
Tue 7/1411:05 am
ACK
- SGF
2 stops12h 34m
American Airlines
Deal found 2/1![American Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/271:57 pm
JLN
- ACK
2 stops23h 54m
United Airlines
Thu 7/3010:18 am
ACK
- JLN
2 stops28h 03m
United Airlines
Deal found 1/31![United Airlines logo]()
$1,120
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:09 am
SGF
- ACK
2 stops8h 19m
American Airlines
Mon 7/2010:24 am
ACK
- SGF
2 stops12h 15m
American Airlines
Deal found 2/2![American Airlines logo]()
$705
This Expedia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/162:47 pm
STL
- MVY
2 stops17h 27m
Multiple Airlines
Fri 2/207:09 am
MVY
- STL
2 stops17h 50m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$1,508
Last-minute flights from Missouri to Cape Cod and the IslandsDiscover last-minute flight deals from Missouri to Cape Cod and the Islands. Data last updated February 4, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Cape Cod and the Islands. Data last updated February 4, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/162:47 pm
STL
- MVY
2 stops17h 27m
Multiple Airlines
Fri 2/207:09 am
MVY
- STL
2 stops17h 50m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$1,508
One-way flights from Missouri to Cape Cod and the IslandsSearch for one-way flight options from Missouri to Cape Cod and the Islands. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
Search for one-way flight options from Missouri to Cape Cod and the Islands. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:25 am
STL
- MVY
1 stop6h 57m
Delta
Deal found 2/2![Delta logo]()
$364
Find flight deals from Missouri to Cape Cod and the Islands
Keep the following information in mind while searching for Missouri to Cape Cod and the Islands flight deals. Data was last updated February 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $631 (American Airlines) |
One-way from | $364 (Delta) |
Popular in | January |
Cheapest in | September |
Average price | $447 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Cape Cod and the Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Missouri to Cape Cod and the Islands that are best for you.
Fly from
Missouri
Fly to
Cape Cod and the Islands
Route
Depart
Return
Price
SpringfieldNantucket
SGF - ACK
SGFACK
Springfield-Branson
Thu 7/9
7:56 pm-1:49 pm
2 stops16h 53m
Nantucket Memorial
Tue 7/14
11:05 am-10:39 pm
2 stops12h 34m
$631
SpringfieldNantucket
SGF - ACK
SGFACK
Springfield-Branson
Wed 7/15
7:09 am-4:28 pm
2 stops8h 19m
Nantucket Memorial
Mon 7/20
10:24 am-9:39 pm
2 stops12h 15m
$705
JoplinNantucket
JLN - ACK
JLNACK
Joplin
Mon 7/27
1:57 pm-2:51 pm
2 stops23h 54m
Nantucket Memorial
Thu 7/30
10:18 am-1:21 pm
2 stops28h 03m
$1,120
St. LouisWest Tisbury
STL - MVY
STLMVY
Lambert-St Louis
Mon 2/16
2:47 pm-9:14 am
2 stops17h 27m
West Tisbury Martha's Vineyard
Fri 2/20
7:09 am-11:59 pm
2 stops17h 50m
$1,508
St. LouisWest Tisbury
STL - MVY
STLMVY
Lambert-St Louis
Sat 6/6
7:25 am-3:22 pm
1 stop6h 57m
$364
Best time to book a flight from Missouri to Cape Cod and the Islands
Have a flexible travel schedule? Discover the best time to fly to Cape Cod and the Islands from Missouri with our price prediction graph.
STL-MVY
SGF-ACK
JLN-ACK
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Cape Cod and the Islands
USMO-zzKDT
STL-MVY
SGF-ACK
JLN-ACK
No data available for this route at this time. Please check back soon.
Related info for your journey
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Complete your trip
Complete your trip to Cape Cod and the Islands by adding a car rental and/or hotel reservation to your travel itinerary.
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Missouri and Cape Cod and the Islands flights
Browse other Missouri and Cape Cod and the Islands flight options. Last updated on February 4, 2026.
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Top 2 airlines flying from Missouri to Cape Cod and the Islands
Discover the top 2 airlines that operate flights from Missouri to Cape Cod and the Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$260 | Average$472 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$293 | Average$653 | FlexibilityNo cancel fee | On-timeN/A |