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$145+ Cheap flights from Panama to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLO
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Panama to Cali

Keep the following information in mind while searching for Panama to Cali flight deals. Data was last updated September 17, 2025.

Round-trip from

$267
(Copa Airlines)

One-way from

$145
(Copa Airlines)

Popular in

July

Cheapest in

April

Average price

$234

Good round-trip deal

$146 or less

Good one-way deal

$166 or less
From Panama to Cali Alfonso B. Aragon Intl
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One-way flight from Panama to Cali Alfonso B. Aragon Intl
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Highest demand for flights based on searches. 10% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Panama to Cali Alfonso B. Aragon Intl.
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Price to beat on a one-way flight from Panama to Cali Alfonso B. Aragon Intl.
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Find flight deals from Panama to Cali

Cheapest flights from Panama to Cali
Explore the most affordable flight options available from Panama to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2412:43 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Sat 11/112:04 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/15$267
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/253:20 amPTY - CLO
1 stop4h 15mAvianca
Mon 9/2911:23 amCLO - PTY
1 stop5h 07mAvianca
Deal found 9/15$273
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
Sun 12/78:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/15$278
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2612:29 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Mon 2/98:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/15$288
This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:55 amPTY - CLO
1 stop4h 40mAvianca
Thu 12/118:40 pmCLO - PTY
1 stop4h 20mAvianca
Deal found 9/15$293
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/19:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
Tue 11/183:12 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/15$299
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/159:46 pmPTY - CLO
Nonstop1h 36mCopa Airlines
Mon 9/228:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/15$301
This Avianca deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/19:45 amPTY - CLO
1 stop5h 00mAvianca
Tue 11/188:15 pmCLO - PTY
1 stop4h 45mAvianca
Deal found 9/16$307
This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:45 amPTY - CLO
1 stop5h 00mAvianca
Fri 12/268:15 pmCLO - PTY
1 stop4h 25mAvianca
Deal found 9/14$313
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
Thu 12/115:01 amCLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 9/17$320
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/13:20 amPTY - CLO
1 stop4h 15mMultiple Airlines
Wed 10/812:01 pmCLO - PTY
Nonstop1h 31mMultiple Airlines
Deal found 9/17$321
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/243:20 amPTY - CLO
1 stop4h 15mMultiple Airlines
Fri 9/268:48 amCLO - PTY
Nonstop1h 32mMultiple Airlines
Deal found 9/17$322

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Panama to Cali that are best for you.

Fly from

Panama

Fly to

Cali

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sat 10/25

9:20 am-10:58 am

Nonstop1h 38m

Cali Alfonso B. Aragon Intl

Sun 11/9

8:48 am-10:20 am

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 10/24

12:43 pm-2:25 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Sat 11/8

3:12 pm-4:44 pm

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 11/10

3:47 pm-5:29 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Fri 11/28

3:12 pm-4:44 pm

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 10/3

9:20 am-10:58 am

Nonstop1h 38m

Cali Alfonso B. Aragon Intl

Wed 10/8

12:01 pm-1:32 pm

Nonstop1h 31m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 11/7

3:47 pm-5:29 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Mon 11/10

8:48 am-10:20 am

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 10/15

12:43 pm-2:25 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Wed 10/22

3:23 pm-4:55 pm

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 10/2

9:16 am-10:54 am

Nonstop1h 38m

Cali Alfonso B. Aragon Intl

Wed 10/8

12:01 pm-1:32 pm

Nonstop1h 31m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 10/6

12:43 pm-2:25 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Wed 10/8

12:01 pm-1:32 pm

Nonstop1h 31m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 11/14

12:29 pm-2:11 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Sun 11/16

12:04 pm-1:36 pm

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sun 10/19

12:43 pm-2:25 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Fri 10/24

12:01 pm-1:32 pm

Nonstop1h 31m

$267

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 17 results
1
2

Best time to book a flight from Panama to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Cali

What is the cheapest month to book a flight from Panama to Cali?

Currently, January is the cheapest month in which you can book a flight from Panama to Cali (average of $351). Flying from Panama to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to CLO?

Find hourly flight availability from Panama to Cali. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 40% on flights from Panama to Cali by exploring options for tickets in the morning.

Weekly flight availability from Panama to Cali

Explore weekly flight availability from Panama to Cali. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2025.

The most flights from PA0 to CLO are scheduled on a Monday (8 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (8 on average).

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated September 17, 2025.
Read through reviews of airlines operating flights from Panama to Cali, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,533 reviews

Entertainment

6.8

Food

6.8

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,533 reviews
Copa Airlines
7.6
Good
1,533 reviews

Entertainment

6.8

Food

6.8

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,436 reviews
Copa Airlines
7.6
Good
1,533 reviews

Entertainment

6.8

Food

6.8

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cali from Panama?

    If you book a flight to Cali from Panama, you will be flying to Alfonso B. Aragon Intl, which is the city’s only airport. Cali Alfonso B. Aragon Intl (CLO) is located 12.1 mi from the center of Cali.

  • How popular is this Panama to Cali flight route?

    Flights from Panama to Cali Alfonso B. Aragon Intl have been viewed 1 times in the past calendar month.

  • How long is the flight from Panama to Cali?

    A quick flight from Panama to Cali can take about 1h 38m. Copa Airlines provides one of the quickest options available for as low as $267. There are 434 mi between Panama and Cali. Generally, flights for this route are nonstop.

  • What are the most reliable airlines from Panama to Cali?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Panama to Cali on time: Copa Airlines (91%), KLM (88%), Turkish Airlines (88%).

  • What are the cheapest flights from Panama to Cali?

    Looking for the cheapest flight from Panama to Cali? While on average our users pay $216, our data indicates the cheapest price to be $115. The most popular route (Panama City Tocumen Intl - Cali Alfonso B. Aragon Intl), is priced around $226.

  • Can I find deals for flights from Panama to Cali that include hotel bookings?

    Yes. In addition to deals on Panama to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Cali.

  • Can I find deals for business class flights from Panama to Cali?

    Yes. Cheapflights offers flight deals from Panama to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Cali?

    Currently, January is the cheapest month in which you can book a flight from Panama to Cali (average of $351). Flying from Panama to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Cali

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Panama to Cali

Discover the top 3 airlines that operate flights from Panama to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$71Average$169FlexibilityNo cancel feeOn-time83%
Copa AirlinesCheapest$112Average$266FlexibilityNo cancel feeOn-time70%
AviancaCheapest$210Average$256FlexibilityNo cancel feeOn-time71%

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