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$161+ Cheap flights from Panama to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLO
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from Panama to Cali

Cheapest flights from Panama to Cali
Explore the most affordable flight options available from Panama to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:55 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Thu 1/1512:03 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/15$299
This Priceline deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:50 pmPTY - CLO
1 stop4h 45mAvianca
Wed 1/148:15 pmCLO - PTY
1 stop4h 25mAvianca
Deal found 12/16$305
This Avianca deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:55 pmPTY - CLO
1 stop5h 00mAvianca
Wed 12/318:15 pmCLO - PTY
1 stop4h 25mAvianca
Deal found 12/15$307
This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2912:29 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Wed 1/218:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/16$310
This Priceline deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:55 pmPTY - CLO
1 stop4h 35mAvianca
Fri 1/98:15 pmCLO - PTY
1 stop4h 25mAvianca
Deal found 12/15$316
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/279:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
Tue 1/208:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/15$320
This Priceline deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:50 pmPTY - CLO
1 stop5h 20mAvianca
Sun 1/118:15 pmCLO - PTY
1 stop4h 45mAvianca
Deal found 12/16$323
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:55 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Sun 1/2512:03 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/15$329
This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/223:55 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Thu 1/153:11 pmCLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 12/16$340
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:29 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Fri 12/266:37 pmCLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 12/15$342
This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:29 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Tue 1/208:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/16$352
This Priceline deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:55 pmPTY - CLO
1 stop4h 35mAvianca
Thu 1/228:20 amCLO - PTY
1 stop5h 40mAvianca
Deal found 12/16$357

Find flight deals from Panama to Cali

Keep the following information in mind while searching for Panama to Cali flight deals. Data was last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$299
(Copa Airlines)

One-way from

$161
(Copa Airlines)

Popular in

December

Cheapest in

May

Average price

$284

Good round-trip deal

$298 or less

Good one-way deal

$173 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Cali Alfonso B. Aragon Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Cali Alfonso B. Aragon Intl flights.
Search Deals
From Panama to Cali Alfonso B. Aragon Intl
Search Deals
One-way flight from Panama to Cali Alfonso B. Aragon Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($17 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Panama to Cali Alfonso B. Aragon Intl.
Search Deals
Price to beat on a one-way flight from Panama to Cali Alfonso B. Aragon Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Panama to Cali that are best for you.

Fly from

Panama

Fly to

Cali

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 2/13

4:00 pm-5:50 pm

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

Mon 2/16

5:03 am-6:34 am

Nonstop1h 31m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 2/19

9:25 am-11:05 am

Nonstop1h 40m

Cali Alfonso B. Aragon Intl

Wed 2/25

8:48 am-10:20 am

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 1/8

9:20 am-11:00 am

Nonstop1h 40m

Cali Alfonso B. Aragon Intl

Sat 1/24

3:11 pm-4:44 pm

Nonstop1h 33m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 2/13

12:29 pm-2:10 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Fri 2/20

3:11 pm-4:44 pm

Nonstop1h 33m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 12/31

9:55 pm-11:37 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Thu 1/15

12:03 pm-1:35 pm

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 1/26

12:29 pm-2:10 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Mon 2/16

12:03 pm-1:35 pm

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 1/9

12:29 pm-2:10 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 1/13

12:03 pm-1:35 pm

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 1/16

9:20 am-11:00 am

Nonstop1h 40m

Cali Alfonso B. Aragon Intl

Mon 1/26

12:03 pm-1:35 pm

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sat 1/24

9:20 am-11:00 am

Nonstop1h 40m

$161

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 2/9

12:29 pm-2:10 pm

Nonstop1h 41m

$161

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 16 results
1
2

Best time to book a flight from Panama to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Cali

What is the cheapest month to book a flight from Panama to Cali?

Currently, April is the cheapest month in which you can book a flight from Panama to Cali (average of $70). Flying from Panama to Cali in July is currently the most expensive (average of $122). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to CLO?

Find hourly flight availability from Panama to Cali. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 59% on flights from Panama to Cali by exploring options for tickets at noon.

Weekly flight availability from Panama to Cali

Explore weekly flight availability from Panama to Cali. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 16, 2025.

The most flights from PA0 to CLO are scheduled on a Monday (8 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (6 on average).

How often are flights from Panama to Cali delayed?

About 5% of weekly flights between Panama and Cali have experienced delays in the past year, with the average delay time being 100 minutes.

What is the most punctual flight time for Panama to Cali flights?

Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Thursday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Panama to Cali flights?

Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 5% of flights being delayed.

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated December 16, 2025.
Read through reviews of airlines operating flights from Panama to Cali, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,556 reviews

Comfort

7.4

Boarding

7.8

Entertainment

6.8

Overall

7.6

Food

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,556 reviews
Copa Airlines
7.6
Good
1,556 reviews

Comfort

7.4

Boarding

7.8

Entertainment

6.8

Overall

7.6

Food

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,484 reviews
Copa Airlines
7.6
Good
1,556 reviews

Comfort

7.4

Boarding

7.8

Entertainment

6.8

Overall

7.6

Food

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cali from Panama?

    If you book a flight to Cali from Panama, you will be flying to Alfonso B. Aragon Intl, which is the city’s only airport. Cali Alfonso B. Aragon Intl (CLO) is located 12.1 mi from the center of Cali.

  • How popular is this Panama to Cali flight route?

    Flights from Panama to Cali Alfonso B. Aragon Intl have been viewed 1 times in the past calendar month.

  • How long is the flight from Panama to Cali?

    A quick flight from Panama to Cali can take about 1h 50m. Copa Airlines provides one of the quickest options available for as low as $299. There are 434 mi between Panama and Cali. Generally, flights for this route are nonstop.

  • What are the cheapest airlines to fly from Panama to Cali one-way?

    The cheapest airlines for a one-way flight from Panama to Cali are Wingo ($66), Avianca ($119), and Copa Airlines ($123).

  • What are the most reliable airlines from Panama to Cali?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Panama to Cali on time: KLM (98%), Turkish Airlines (98%), Copa Airlines (95%).

  • What are the cheapest flights from Panama to Cali?

    Looking for the cheapest flight from Panama to Cali? While on average our users pay $274, our data indicates the cheapest price to be $123. The most popular route (Panama City Tocumen Intl - Cali Alfonso B. Aragon Intl), is priced around $194.

  • Can I find deals for flights from Panama to Cali that include hotel bookings?

    Yes. In addition to deals on Panama to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Cali.

  • Can I find deals for business class flights from Panama to Cali?

    Yes. Cheapflights offers flight deals from Panama to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Cali?

    Currently, April is the cheapest month in which you can book a flight from Panama to Cali (average of $70). Flying from Panama to Cali in July is currently the most expensive (average of $122). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Cali

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Panama to Cali

Discover the top 3 airlines that operate flights from Panama to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$73Average$171FlexibilityNo cancel feeOn-time83%
Copa AirlinesCheapest$122Average$260FlexibilityNo cancel feeOn-time70%
AviancaCheapest$211Average$259FlexibilityNo cancel feeOn-time71%

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