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$165+ Cheap flights from Guayaquil (GYE) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — CLO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Guayaquil Jose Joaquin de Olmedo to Cali Alfonso B. Aragon Intl are usually found in January or September, booked 67 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Guayaquil to Cali

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$284
(Copa Airlines)

One-way from

$165
(Copa Airlines)

Popular in

August

Cheapest in

January

Average price

$264
From Guayaquil Jose Joaquin de Olmedo to Cali Alfonso B. Aragon Intl
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One-way flight from Guayaquil Jose Joaquin de Olmedo to Cali Alfonso B. Aragon Intl
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Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($2 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Guayaquil to Cali

Cheapest flights from Guayaquil to Cali
Explore the most affordable flight options available from Guayaquil to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:30 amGYE - CLO
1 stop9h 07mCopa Airlines
Wed 1/148:48 amCLO - GYE
1 stop11h 58mCopa Airlines
Deal found 9/11$284
This Priceline deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:35 amGYE - CLO
1 stop4h 43mAvianca
Tue 9/309:14 amCLO - GYE
1 stop4h 26mAvianca
Deal found 9/10$287
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:30 amGYE - CLO
1 stop9h 07mCopa Airlines
Thu 1/1512:03 pmCLO - GYE
1 stop8h 43mCopa Airlines
Deal found 9/11$299
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/128:30 amGYE - CLO
1 stop5h 41mCopa Airlines
Tue 11/184:52 amCLO - GYE
1 stop8h 42mCopa Airlines
Deal found 9/10$327
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:35 amGYE - CLO
1 stop4h 43mMultiple Airlines
Tue 9/3010:41 pmCLO - GYE
2 stops18h 09mMultiple Airlines
Deal found 9/10$337
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/158:30 amGYE - CLO
1 stop5h 41mCopa Airlines
Sat 11/228:48 amCLO - GYE
1 stop4h 46mCopa Airlines
Deal found 9/10$341
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/273:54 pmGYE - CLO
2 stops15h 28mLATAM Airlines
Tue 9/3010:41 pmCLO - GYE
2 stops18h 09mLATAM Airlines
Deal found 9/10$343
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/308:32 amGYE - CLO
1 stop5h 49mCopa Airlines
Sun 10/57:08 pmCLO - GYE
1 stop4h 45mCopa Airlines
Deal found 9/10$344
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/288:30 amGYE - CLO
1 stop5h 41mCopa Airlines
Sat 11/18:48 amCLO - GYE
1 stop4h 46mCopa Airlines
Deal found 9/10$353

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Guayaquil to Cali that are best for you.

Fly from

Guayaquil

Fly to

Cali

Route

Depart

Return

Price

GuayaquilCali

GYE - CLO

GYECLO

Guayaquil Jose Joaquin de Olmedo

Tue 12/30

8:30 am-5:37 pm

1 stop9h 07m

Cali Alfonso B. Aragon Intl

Wed 1/14

8:48 am-8:46 pm

1 stop11h 58m

$284

GuayaquilCali

GYE - CLO

GYECLO

Guayaquil Jose Joaquin de Olmedo

Tue 12/30

8:30 am-5:37 pm

1 stop9h 07m

Cali Alfonso B. Aragon Intl

Thu 1/15

12:03 pm-8:46 pm

1 stop8h 43m

$299

GuayaquilCali

GYE - CLO

GYECLO

Guayaquil Jose Joaquin de Olmedo

Thu 1/8

8:34 am-2:10 pm

1 stop5h 36m

Cali Alfonso B. Aragon Intl

Sat 1/24

12:03 pm-8:46 pm

1 stop8h 43m

$327

GuayaquilCali

GYE - CLO

GYECLO

Guayaquil Jose Joaquin de Olmedo

Sun 11/16

4:31 am-11:01 am

1 stop6h 30m

Cali Alfonso B. Aragon Intl

Thu 11/20

12:04 pm-11:55 pm

1 stop11h 51m

$327

GuayaquilCali

GYE - CLO

GYECLO

Guayaquil Jose Joaquin de Olmedo

Fri 11/14

8:30 am-2:11 pm

1 stop5h 41m

Cali Alfonso B. Aragon Intl

Tue 11/18

12:04 pm-8:43 pm

1 stop8h 39m

$339

GuayaquilCali

GYE - CLO

GYECLO

Guayaquil Jose Joaquin de Olmedo

Sat 2/14

8:34 am-2:10 pm

1 stop5h 36m

Cali Alfonso B. Aragon Intl

Sat 2/21

8:48 am-11:55 pm

1 stop15h 07m

$344

GuayaquilCali

GYE - CLO

GYECLO

Guayaquil Jose Joaquin de Olmedo

Wed 10/29

8:30 am-2:11 pm

1 stop5h 41m

Cali Alfonso B. Aragon Intl

Tue 11/4

12:04 pm-11:55 pm

1 stop11h 51m

$359

GuayaquilCali

GYE - CLO

GYECLO

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

8:30 am-2:11 pm

1 stop5h 41m

Cali Alfonso B. Aragon Intl

Tue 11/25

4:52 am-1:34 pm

1 stop8h 42m

$365

GuayaquilCali

GYE - CLO

GYECLO

Guayaquil Jose Joaquin de Olmedo

Sat 11/15

8:30 am-2:11 pm

1 stop5h 41m

Cali Alfonso B. Aragon Intl

Mon 11/17

4:52 am-1:34 pm

1 stop8h 42m

$369

GuayaquilCali

GYE - CLO

GYECLO

Guayaquil Jose Joaquin de Olmedo

Mon 11/3

8:30 am-2:11 pm

1 stop5h 41m

Cali Alfonso B. Aragon Intl

Sat 11/8

12:04 pm-11:41 pm

1 stop11h 37m

$371

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 20 results
1
2

Best time to book a flight from Guayaquil to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to Cali

How far ahead should I book a flight from Guayaquil to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Guayaquil to Cali. Price data was last updated on August 29, 2025.

To ensure you get the cheapest price possible for a flight from Guayaquil to Cali, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Guayaquil to Cali?

Currently, January is the cheapest month in which you can book a flight from Guayaquil to Cali (average of $351). Flying from Guayaquil to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to CLO?

Find hourly flight availability from Guayaquil to Cali. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

One of the essential ways to save on airfare from Guayaquil to Cali is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 20% on airfare.

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Guayaquil to Cali to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,436 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Guayaquil to Cali?

    For as low as $284, Copa Airlines can have you in Cali from Guayaquil in 9h 07m. There are 462 mi between Guayaquil and Cali.

  • What are the cheapest airlines flying from Guayaquil to Cali round-trip?

    Our cheapest airline available from Guayaquil to Cali is Avianca. Our recent data shows that you can find tickets from as low as $233 on this airline. An additional option worth looking into is Copa Airlines, starting at $245. Users have found that Avianca is 17% cheaper than the other options available to this destination.

  • Can I find deals for flights from Guayaquil to Cali that include hotel bookings?

    Yes. In addition to deals on Guayaquil to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to Cali.

  • Can I find deals for business class flights from Guayaquil to Cali?

    Yes. Cheapflights offers flight deals from Guayaquil to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to Cali?

    Currently, January is the cheapest month in which you can book a flight from Guayaquil to Cali (average of $351). Flying from Guayaquil to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Guayaquil to Cali

Discover the top 2 airlines that operate flights from Guayaquil to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$233Average$318FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$245Average$337FlexibilityNo cancel feeOn-time70%

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