$232+ Cheap flights from Cali (CLO) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — GYE
Sep 23 — Sep 301
Round-trip
1 adult, Economy
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Find cheap flights from Cali to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Cali to Guayaquil
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One-way
Cheapest flights from Cali to GuayaquilExplore the most affordable flight options available from Cali to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
Explore the most affordable flight options available from Cali to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:06 pm -
1 stop5h 24m
Mon 10/268:23 am -
1 stop5h 48m
Deal found 8/20![Copa Airlines logo]()
$388
This Copa Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:48 am -
1 stop14h 49m
Sun 9/136:28 pm -
1 stop23h 05m
Deal found 8/24![Copa Airlines logo]()
$389
This Avianca deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:45 pm -
1 stop4h 05m
Tue 10/139:10 am -
1 stop6h 25m
Deal found 8/24![Avianca logo]()
$393
This Avianca deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:30 am -
1 stop4h 40m
Fri 12/114:20 pm -
1 stop5h 25m
Deal found 8/21![Avianca logo]()
$394
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:02 pm -
1 stop5h 34m
Thu 12/248:25 am -
1 stop5h 41m
Deal found 8/21![Copa Airlines logo]()
$399
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:27 pm -
1 stop5h 35m
Fri 8/288:28 am -
1 stop5h 44m
Deal found 8/20![Copa Airlines logo]()
$404
This Copa Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:08 pm -
1 stop23h 13m
Tue 9/86:28 pm -
1 stop19h 44m
Deal found 8/24![Copa Airlines logo]()
$405
This Avianca deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:15 pm -
1 stop6h 10m
Wed 12/233:30 am -
1 stop6h 15m
Deal found 8/24![Avianca logo]()
$413
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:38 am -
1 stop16h 19m
Thu 12/312:45 pm -
1 stop20h 15m
Deal found 8/21![Copa Airlines logo]()
$416
This LATAM Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:45 am -
2 stops12h 52m
Sun 9/202:25 pm -
2 stops15h 40m
Deal found 8/24![LATAM Airlines logo]()
$417
This Copa Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:38 pm -
1 stop16h 43m
Tue 9/86:28 pm -
1 stop19h 44m
Deal found 8/23![Copa Airlines logo]()
$424
Best flights from Cali to GuayaquilDiscover carefully curated flight deals from Cali to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
Discover carefully curated flight deals from Cali to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:08 pm -
1 stop5h 22m
Mon 10/268:23 am -
1 stop9h 28m
Deal found 8/20![Copa Airlines logo]()
$388
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:48 am -
1 stop14h 49m
Sun 9/204:13 am -
1 stop9h 59m
Deal found 8/20![Copa Airlines logo]()
$388
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/48:39 am -
1 stop8h 58m
Sun 2/78:26 am -
1 stop5h 42m
Deal found 8/20![Copa Airlines logo]()
$388
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:18 pm -
1 stop22h 22m
Tue 11/35:58 am -
1 stop17h 34m
Deal found 8/20![Copa Airlines logo]()
$388
This Copa Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:18 pm -
1 stop5h 35m
Sun 11/16:38 pm -
1 stop22h 54m
Deal found 8/24![Copa Airlines logo]()
$389
This Copa Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:06 pm -
1 stop5h 24m
Tue 11/36:38 pm -
1 stop16h 19m
Deal found 8/23![Copa Airlines logo]()
$389
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:08 pm -
1 stop11h 53m
Thu 9/176:28 pm -
1 stop16h 40m
Deal found 8/21![Copa Airlines logo]()
$389
This Copa Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:06 pm -
1 stop11h 55m
Sun 10/2512:23 pm -
1 stop4h 46m
Deal found 8/23![Copa Airlines logo]()
$389
Last-minute flights from Cali to GuayaquilDiscover last-minute flight deals from Cali to Guayaquil. Data last updated August 24, 2026 and is based on user searches.
Discover last-minute flight deals from Cali to Guayaquil. Data last updated August 24, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:48 am -
1 stop8h 42m
Mon 9/76:28 pm -
1 stop19h 44m
Deal found 8/20![Copa Airlines logo]()
$404
This Copa Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:08 pm -
1 stop23h 13m
Tue 9/86:28 pm -
1 stop19h 44m
Deal found 8/24![Copa Airlines logo]()
$405
This Copa Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:38 pm -
1 stop16h 43m
Tue 9/86:28 pm -
1 stop19h 44m
Deal found 8/23![Copa Airlines logo]()
$424
This Copa Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:48 am -
1 stop14h 49m
Sun 9/136:28 pm -
1 stop23h 05m
Deal found 8/24![Copa Airlines logo]()
$389
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:08 pm -
1 stop11h 29m
Sun 9/206:28 pm -
1 stop23h 05m
Deal found 8/20![Copa Airlines logo]()
$388
This Avianca deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:40 am -
2 stops6h 40m
Sun 9/209:05 am -
1 stop6h 30m
Deal found 8/20![Avianca logo]()
$415
This LATAM Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:45 am -
2 stops12h 52m
Sun 9/202:25 pm -
2 stops15h 40m
Deal found 8/24![LATAM Airlines logo]()
$417
One-way flights from Cali to GuayaquilSearch for one-way flight options from Cali to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
Search for one-way flight options from Cali to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:25 pm -
1 stop16h 56m
Deal found 8/20![Copa Airlines logo]()
$232
This Copa Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1312:08 pm -
1 stop23h 13m
Deal found 8/23![Copa Airlines logo]()
$233
Find flight deals from Cali to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $388 (Copa Airlines) |
One-way from | $232 (Copa Airlines) |
Popular in | April |
Cheapest in | February |
Average price | $390 |
Cheapflights Fare Finder
Customize your flight search to find flights from Cali to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 24, 2026.
Use the filters below to find and compare flights from Cali to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CaliGuayaquil
CLO Cali Alfonso B. Aragon Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLOGYE
Cali Alfonso B. Aragon Intl
Tue 9/29
12:08 pm-5:30 pm
1 stop5h 22m
Guayaquil Jose Joaquin de Olmedo
Mon 10/26
8:23 am-5:51 pm
1 stop9h 28m
$388
CaliGuayaquil
CLO Cali Alfonso B. Aragon Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLOGYE
Cali Alfonso B. Aragon Intl
Tue 9/15
8:48 am-11:37 pm
1 stop14h 49m
Guayaquil Jose Joaquin de Olmedo
Sun 9/20
4:13 am-2:12 pm
1 stop9h 59m
$388
Quickest round-trip
CaliGuayaquil
CLO Cali Alfonso B. Aragon Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLOGYE
Cali Alfonso B. Aragon Intl
Thu 2/4
8:39 am-5:37 pm
1 stop8h 58m
Guayaquil Jose Joaquin de Olmedo
Sun 2/7
8:26 am-2:08 pm
1 stop5h 42m
$388
CaliGuayaquil
CLO Cali Alfonso B. Aragon Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLOGYE
Cali Alfonso B. Aragon Intl
Thu 10/29
3:18 pm-1:40 pm
1 stop22h 22m
Guayaquil Jose Joaquin de Olmedo
Tue 11/3
5:58 am-11:32 pm
1 stop17h 34m
$388
CaliGuayaquil
CLO Cali Alfonso B. Aragon Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLOGYE
Cali Alfonso B. Aragon Intl
Wed 10/28
3:18 pm-8:53 pm
1 stop5h 35m
Guayaquil Jose Joaquin de Olmedo
Sun 11/1
6:38 pm-5:32 pm
1 stop22h 54m
$389
CaliGuayaquil
CLO Cali Alfonso B. Aragon Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLOGYE
Cali Alfonso B. Aragon Intl
Fri 10/16
12:06 pm-5:30 pm
1 stop5h 24m
Guayaquil Jose Joaquin de Olmedo
Tue 11/3
6:38 pm-10:57 am
1 stop16h 19m
$389
CaliGuayaquil
CLO Cali Alfonso B. Aragon Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLOGYE
Cali Alfonso B. Aragon Intl
Sat 9/5
12:08 pm-12:01 am
1 stop11h 53m
Guayaquil Jose Joaquin de Olmedo
Thu 9/17
6:28 pm-11:08 am
1 stop16h 40m
$389
CaliGuayaquil
CLO Cali Alfonso B. Aragon Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLOGYE
Cali Alfonso B. Aragon Intl
Wed 10/21
12:06 pm-12:01 am
1 stop11h 55m
Guayaquil Jose Joaquin de Olmedo
Sun 10/25
12:23 pm-5:09 pm
1 stop4h 46m
$389
Cheapest one-way
Quickest one-way
CaliGuayaquil
CLO Cali Alfonso B. Aragon Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLOGYE
Cali Alfonso B. Aragon Intl
Mon 10/12
6:25 pm-11:21 am
1 stop16h 56m
$232
CaliGuayaquil
CLO Cali Alfonso B. Aragon Intl - GYE Guayaquil Jose Joaquin de Olmedo
CLOGYE
Cali Alfonso B. Aragon Intl
Sun 9/13
12:08 pm-11:21 am
1 stop23h 13m
$233
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Cali-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cali-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cali-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Cali-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cali-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Cali to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cali with our price prediction graph.
CLO-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Cali to Guayaquil
How far ahead should I book a flight from Cali to Guayaquil?
The best time to book flights from Cali to Guayaquil is 21 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Cali to Guayaquil?
Currently, February is the cheapest month in which you can book a flight from Cali to Guayaquil (average of $298). Flying from Cali to Guayaquil in April is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Cali to Guayaquil?
Airfare is typical for this route at the moment.
Cali to Guayaquil flights typically cost between $346 and $422 in October.The cheapest round-trip price found within the last 5 days was $388 on Copa Airlines (Oct 16-Oct 18).
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated August 24, 2026.
Read reviews from past customers who have flown Avianca from Cali to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
6.5
Entertainment
5.3
Food
5.0
Boarding
6.9
Comfort
6.2
Crew
7.2
Reviews
1 / 20
6.0
GoodAnonymous,Aug 2026
BOG - ORD
Overall
6.5
Entertainment
5.3
Food
5.0
Boarding
6.9
Comfort
6.2
Crew
7.2
Reviews
1 / 20
6.0
GoodAnonymous,Aug 2026
BOG - ORD
Related info for your journey
Find useful and relevant information for your journey from Cali to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top airline flying from Cali to Guayaquil
Discover the top airline that operate flights from Cali to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$262 | Average$361 | FlexibilityNo cancel fee | On-time71% |