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Guayaquil

$242+ Cheap flights from Cali (CLO) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — GYE
Jun 23 — Jun 301
Tue 6/23
Tue 6/30
1 adult, Economy
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Cheap flight deals from Cali to Guayaquil

Cheapest flights from Cali to Guayaquil
Explore the most affordable flight options available from Cali to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.

This Avianca deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1112:50 pm
CLO
-
GYE
1 stop4h 45m
Avianca
Tue 7/146:50 pm
GYE
-
CLO
1 stop4h 50m
Avianca
Deal found 5/20$380
This Copa Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1112:06 pm
CLO
-
GYE
1 stop5h 25m
Copa Airlines
Tue 7/142:36 pm
GYE
-
CLO
1 stop23h 34m
Copa Airlines
Deal found 5/23$381
This Avianca deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1112:50 pm
CLO
-
GYE
1 stop4h 45m
Avianca
Fri 7/36:50 pm
GYE
-
CLO
1 stop4h 50m
Avianca
Deal found 5/23$382
This Copa Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:46 am
CLO
-
GYE
1 stop12h 06m
Copa Airlines
Sun 5/316:00 am
GYE
-
CLO
1 stop8h 10m
Copa Airlines
Deal found 5/23$398
This Avianca deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:40 am
CLO
-
GYE
2 stops6h 40m
Avianca
Mon 7/206:50 pm
GYE
-
CLO
1 stop4h 35m
Avianca
Deal found 5/20$401
This Copa Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2912:03 pm
CLO
-
GYE
1 stop8h 56m
Copa Airlines
Sun 1/106:33 pm
GYE
-
CLO
1 stop23h 04m
Copa Airlines
Deal found 5/20$436
This Avianca deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/254:40 am
CLO
-
GYE
2 stops6h 40m
Avianca
Wed 7/224:40 pm
GYE
-
CLO
2 stops6h 25m
Avianca
Deal found 5/21$451

Find flight deals from Cali to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$380
(Avianca)

One-way from

$242
(Avianca)

Popular in

April

Cheapest in

February

Average price

$359
Provider with most accurate pricing for Cali Alfonso B. Aragon Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Cali Alfonso B. Aragon Intl-Guayaquil Jose Joaquin de Olmedo flights.
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From Cali Alfonso B. Aragon Intl to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Cali Alfonso B. Aragon Intl to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in May 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from Cali to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Fri 6/19

12:06 pm-5:29 pm

1 stop5h 23m

Guayaquil Jose Joaquin de Olmedo

Mon 7/20

6:27 pm-2:10 pm

1 stop19h 43m

$380
Quickest round-trip

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Thu 6/11

1:10 pm-5:35 pm

1 stop4h 25m

Guayaquil Jose Joaquin de Olmedo

Fri 7/3

6:50 pm-11:40 pm

1 stop4h 50m

$380

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Thu 6/4

3:10 pm-12:01 am

1 stop8h 51m

Guayaquil Jose Joaquin de Olmedo

Fri 6/5

5:59 am-2:10 pm

1 stop8h 11m

$380

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Fri 10/9

6:25 pm-11:37 pm

1 stop5h 12m

Guayaquil Jose Joaquin de Olmedo

Tue 10/13

8:24 am-2:10 pm

1 stop5h 46m

$380

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Thu 7/9

12:06 pm-11:38 pm

1 stop11h 32m

Guayaquil Jose Joaquin de Olmedo

Fri 7/10

8:27 am-5:35 pm

1 stop9h 08m

$380

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Mon 7/20

6:16 pm-12:02 am

1 stop5h 46m

Guayaquil Jose Joaquin de Olmedo

Thu 8/20

6:28 pm-2:12 pm

1 stop19h 44m

$380

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Wed 7/1

3:10 pm-11:22 am

1 stop20h 12m

Guayaquil Jose Joaquin de Olmedo

Tue 7/28

8:27 am-5:35 pm

1 stop9h 08m

$381

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Wed 7/1

12:06 pm-12:02 am

1 stop11h 56m

Guayaquil Jose Joaquin de Olmedo

Wed 7/8

2:36 pm-11:06 am

1 stop20h 30m

$381

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sat 7/11

12:06 pm-12:02 am

1 stop11h 56m

Guayaquil Jose Joaquin de Olmedo

Tue 7/14

6:27 pm-5:35 pm

1 stop23h 08m

$381

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Thu 6/11

12:06 pm-11:20 am

1 stop23h 14m

Guayaquil Jose Joaquin de Olmedo

Mon 6/15

6:27 pm-2:10 pm

1 stop19h 43m

$381

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/21

Showing 1-10 of 11 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Cali-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cali-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cali-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cali-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cali-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cali to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Guayaquil

How far ahead should I book a flight from Cali to Guayaquil?

The best time to book flights from Cali to Guayaquil is 51 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Cali to Guayaquil?

Currently, February is the cheapest month in which you can book a flight from Cali to Guayaquil (average of $298). Flying from Cali to Guayaquil in April is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Cali to Guayaquil?

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated May 24, 2026.
Read reviews from past customers who have flown Avianca from Cali to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Avianca
6.5
Okay
2,526 reviews

Comfort

6.2

Food

5.0

Entertainment

5.3

Boarding

6.9

Crew

7.2

Overall

6.5

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

BOG - BOS

Customer service was great from the counter to the light crew. It would be nice if the airplanes were equipped with in-flight entertainment system for such a longhaul flight.
Avianca
6.5
Okay
2,526 reviews
Avianca
6.5
Okay
2,526 reviews

Comfort

6.2

Food

5.0

Entertainment

5.3

Boarding

6.9

Crew

7.2

Overall

6.5

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

BOG - BOS

Customer service was great from the counter to the light crew. It would be nice if the airplanes were equipped with in-flight entertainment system for such a longhaul flight.

Related info for your journey

Find useful and relevant information for your journey from Cali to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cali to Guayaquil?

    Airlines like Copa Airlines and Avianca fly from Cali to Guayaquil in about 4h 25m. The time it takes to get you to your destination can typically vary by up to 4h 22m. Airlines will cover a distance of 462 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Cali to Guayaquil round-trip?

    Cheapflights users have booked flights from Cali to Guayaquil round-trip from $262. You may be able to fly from Cali to Guayaquil for 23% less than the average price by searching for this airline.

  • Can I find deals for flights from Cali to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Cali to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Guayaquil.

  • Can I find deals for business class flights from Cali to Guayaquil?

    Yes. Cheapflights offers flight deals from Cali to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Guayaquil?

    Currently, February is the cheapest month in which you can book a flight from Cali to Guayaquil (average of $298). Flying from Cali to Guayaquil in April is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Cali to Guayaquil

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Top airline flying from Cali to Guayaquil

Discover the top airline that operate flights from Cali to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$262Average$378FlexibilityNo cancel feeOn-time71%

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