HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$209+ Cheap flights from Cali (CLO) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — GYE
Aug 5 — Aug 121
Wed 8/5
Wed 8/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Cali to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Cali to Guayaquil

Cheapest flights from Cali to Guayaquil
Explore the most affordable flight options available from Cali to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 6, 2026.

This LATAM Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:45 am
CLO
-
GYE
2 stops11h 46m
LATAM Airlines
Mon 7/202:22 pm
GYE
-
CLO
2 stops15h 48m
LATAM Airlines
Deal found 7/2$380
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:00 am
CLO
-
GYE
1 stop6h 35m
Avianca
Sat 7/183:30 am
GYE
-
CLO
1 stop6h 50m
Avianca
Deal found 7/2$381
This Copa Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/113:10 pm
CLO
-
GYE
1 stop5h 43m
Copa Airlines
Tue 7/142:36 pm
GYE
-
CLO
1 stop23h 34m
Copa Airlines
Deal found 7/6$384
This Copa Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:16 pm
CLO
-
GYE
1 stop19h 19m
Copa Airlines
Sat 8/86:28 pm
GYE
-
CLO
1 stop23h 05m
Copa Airlines
Deal found 7/5$385
This Avianca deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:40 am
CLO
-
GYE
1 stop4h 15m
Avianca
Mon 7/206:50 pm
GYE
-
CLO
1 stop4h 50m
Avianca
Deal found 7/6$386
This Expedia deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:40 am
CLO
-
GYE
2 stops15h 05m
LATAM Airlines
Sat 8/229:00 am
GYE
-
CLO
2 stops13h 15m
LATAM Airlines
Deal found 7/1$392
This Copa Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:02 pm
CLO
-
GYE
1 stop5h 34m
Copa Airlines
Thu 12/2412:22 pm
GYE
-
CLO
1 stop5h 11m
Copa Airlines
Deal found 7/3$395
This OneTravel deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/29:20 pm
CLO
-
GYE
2 stops11h 55m
Avianca
Sun 7/59:05 am
GYE
-
CLO
1 stop4h 10m
Avianca
Deal found 7/1$405
This LATAM Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1110:50 pm
CLO
-
GYE
2 stops17h 38m
LATAM Airlines
Tue 7/142:59 pm
GYE
-
CLO
2 stops16h 16m
LATAM Airlines
Deal found 7/2$414

Find flight deals from Cali to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$380
(LATAM Airlines)

One-way from

$209
(LATAM Airlines)

Popular in

April

Cheapest in

February

Average price

$378
Provider with most accurate pricing for Cali Alfonso B. Aragon Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cali Alfonso B. Aragon Intl-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Cali Alfonso B. Aragon Intl to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Cali Alfonso B. Aragon Intl to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Cali to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Thu 7/16

8:46 am-5:31 pm

1 stop8h 45m

Guayaquil Jose Joaquin de Olmedo

Mon 7/20

2:36 pm-2:10 pm

1 stop23h 34m

$384

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sat 8/1

8:48 am-11:38 pm

1 stop14h 50m

Guayaquil Jose Joaquin de Olmedo

Tue 8/11

11:48 am-5:21 pm

1 stop5h 33m

$384
Quickest round-trip

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sat 7/11

3:10 pm-8:53 pm

1 stop5h 43m

Guayaquil Jose Joaquin de Olmedo

Tue 7/14

4:12 am-5:35 pm

1 stop13h 23m

$384

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Fri 8/7

8:48 am-11:38 pm

1 stop14h 50m

Guayaquil Jose Joaquin de Olmedo

Mon 8/10

6:00 am-5:33 pm

1 stop11h 33m

$384

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sat 7/18

12:06 pm-12:02 am

1 stop11h 56m

Guayaquil Jose Joaquin de Olmedo

Fri 7/24

11:48 am-11:06 am

1 stop23h 18m

$384

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Mon 8/17

5:02 am-8:53 pm

1 stop15h 51m

Guayaquil Jose Joaquin de Olmedo

Fri 8/21

4:13 am-11:33 pm

1 stop19h 20m

$384

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Thu 9/24

5:02 am-11:37 pm

1 stop18h 35m

Guayaquil Jose Joaquin de Olmedo

Tue 10/13

6:01 am-11:06 am

1 stop5h 05m

$384
Cheapest one-way

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sat 8/22

9:50 pm-4:28 pm

2 stops18h 38m

$209
Quickest one-way

CaliGuayaquil

CLO - GYE

CLOGYE

Cali Alfonso B. Aragon Intl

Sat 8/22

9:45 am-2:35 pm

1 stop4h 50m

$225

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/3

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Cali-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cali-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cali-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cali-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cali-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cali to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Guayaquil

How far ahead should I book a flight from Cali to Guayaquil?

The best time to book flights from Cali to Guayaquil is 28 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Cali to Guayaquil?

Currently, February is the cheapest month in which you can book a flight from Cali to Guayaquil (average of $298). Flying from Cali to Guayaquil in April is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Cali to Guayaquil?

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated July 6, 2026.
Read reviews from past customers who have flown Avianca from Cali to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Avianca
6.5
Okay
2,520 reviews

Overall

6.5

Food

4.9

Boarding

6.9

Entertainment

5.3

Comfort

6.1

Crew

7.2

Reviews

1 / 20
10.0
Excellent

Ana Victoria,Jun 2026

BOG - SJO

On time, that was the most important because it was too late and we were very tired
Avianca
6.5
Okay
2,520 reviews
Avianca
6.5
Okay
2,520 reviews

Overall

6.5

Food

4.9

Boarding

6.9

Entertainment

5.3

Comfort

6.1

Crew

7.2

Reviews

1 / 20
10.0
Excellent

Ana Victoria,Jun 2026

BOG - SJO

On time, that was the most important because it was too late and we were very tired

Related info for your journey

Find useful and relevant information for your journey from Cali to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cali to Guayaquil?

    Airlines like Copa Airlines fly from Cali to Guayaquil in about 8h 45m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 462 mi.

  • What is the cheapest airline to fly from Cali to Guayaquil round-trip?

    Cheapflights users have booked flights from Cali to Guayaquil round-trip from $262. You may be able to fly from Cali to Guayaquil for 27% less than the average price by searching for this airline.

  • Can I find deals for flights from Cali to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Cali to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Guayaquil.

  • Can I find deals for business class flights from Cali to Guayaquil?

    Yes. Cheapflights offers flight deals from Cali to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Guayaquil?

    Currently, February is the cheapest month in which you can book a flight from Cali to Guayaquil (average of $298). Flying from Cali to Guayaquil in April is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cali to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
Bogotá to Quito flights
Bogotá to Guayaquil flights
Cartagena to Guayaquil flights

Top airline flying from Cali to Guayaquil

Discover the top airline that operate flights from Cali to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$262Average$378FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.