$142+ Cheap flights from St. Louis to Buffalo (STL - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BUF
Mar 5 — Mar 121
1 adult, Economy
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Find cheap flights from St. Louis to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Buffalo
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Best
Last-minute
One-way
Cheapest flights from St. Louis to BuffaloExplore the most affordable flight options available from St. Louis to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from St. Louis to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:20 pm
STL
- BUF
1 stop13h 32m
Frontier
Sun 2/152:19 pm
BUF
- STL
1 stop17h 32m
Frontier
Deal found 1/31![Frontier logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:13 pm
STL
- BUF
1 stop15h 00m
Frontier
Sat 4/181:08 pm
BUF
- STL
1 stop22h 22m
Frontier
Deal found 2/2![Frontier logo]()
$269
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:13 pm
STL
- BUF
1 stop6h 49m
United Airlines
Tue 6/237:00 am
BUF
- STL
1 stop6h 11m
United Airlines
Deal found 2/1![United Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:47 am
STL
- BUF
1 stop26h 02m
Frontier
Sun 3/89:25 pm
BUF
- STL
2 stops16h 54m
Frontier
Deal found 2/1![Frontier logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:13 pm
STL
- BUF
1 stop15h 00m
Frontier
Sun 4/2611:25 am
BUF
- STL
1 stop12h 54m
Frontier
Deal found 2/2![Frontier logo]()
$336
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:12 am
STL
- BUF
1 stop6h 25m
Delta
Mon 3/167:38 pm
BUF
- STL
1 stop5h 20m
Delta
Deal found 2/3![Delta logo]()
$342
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:15 am
STL
- BUF
2 stops7h 00m
Southwest
Mon 8/105:40 am
BUF
- STL
1 stop6h 55m
Southwest
Deal found 2/2![Southwest logo]()
$347
Best flights from St. Louis to BuffaloDiscover carefully curated flight deals from St. Louis to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from St. Louis to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:20 pm
STL
- BUF
2 stops20h 25m
Frontier
Sun 2/152:19 pm
BUF
- STL
1 stop17h 32m
Frontier
Deal found 1/31![Frontier logo]()
$302
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:13 pm
STL
- BUF
1 stop6h 49m
United Airlines
Tue 6/237:00 am
BUF
- STL
1 stop6h 11m
United Airlines
Deal found 2/1![United Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:04 pm
STL
- BUF
1 stop4h 55m
Delta
Sat 6/66:25 am
BUF
- STL
1 stop4h 01m
Delta
Deal found 2/2![Delta logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:55 pm
STL
- BUF
2 stops16h 35m
Frontier
Sat 4/181:08 pm
BUF
- STL
1 stop22h 22m
Frontier
Deal found 2/2![Frontier logo]()
$315
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:59 pm
STL
- BUF
1 stop3h 56m
Delta
Mon 3/167:38 pm
BUF
- STL
1 stop5h 20m
Delta
Deal found 2/1![Delta logo]()
$342
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:04 pm
STL
- BUF
1 stop4h 55m
Delta
Mon 6/89:00 am
BUF
- STL
1 stop5h 17m
Delta
Deal found 2/2![Delta logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- BUF
2 stops20h 40m
Frontier
Sun 3/89:25 pm
BUF
- STL
1 stop10h 37m
Frontier
Deal found 2/2![Frontier logo]()
$348
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:35 am
STL
- BUF
1 stop4h 08m
Delta
Sun 3/86:15 am
BUF
- STL
1 stop4h 31m
Delta
Deal found 2/1![Delta logo]()
$367
Last-minute flights from St. Louis to BuffaloDiscover last-minute flight deals from St. Louis to Buffalo. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Buffalo. Data last updated February 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/48:22 pm
STL
- BUF
2 stops21h 42m
Frontier
Sun 2/81:39 pm
BUF
- STL
1 stop18h 12m
Frontier
Deal found 2/1![Frontier logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/123:49 pm
STL
- BUF
2 stops19h 55m
Multiple Airlines
Sun 2/152:19 pm
BUF
- STL
1 stop17h 32m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$408
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:20 pm
STL
- BUF
1 stop13h 32m
Frontier
Sun 2/152:19 pm
BUF
- STL
1 stop17h 32m
Frontier
Deal found 1/31![Frontier logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:47 am
STL
- BUF
1 stop26h 02m
Frontier
Sun 3/89:25 pm
BUF
- STL
2 stops16h 54m
Frontier
Deal found 2/1![Frontier logo]()
$319
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:35 am
STL
- BUF
1 stop4h 08m
Delta
Sun 3/86:02 am
BUF
- STL
1 stop7h 17m
Delta
Deal found 2/3![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:41 am
STL
- BUF
2 stops10h 01m
United Airlines
Sun 3/86:07 am
BUF
- STL
2 stops9h 35m
United Airlines
Deal found 2/1![United Airlines logo]()
$407
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:35 am
STL
- BUF
2 stops6h 40m
Southwest
Sun 3/86:00 pm
BUF
- STL
2 stops7h 15m
Southwest
Deal found 2/2![Southwest logo]()
$417
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:12 am
STL
- BUF
1 stop6h 25m
Delta
Mon 3/167:38 pm
BUF
- STL
1 stop5h 20m
Delta
Deal found 2/3![Delta logo]()
$342
One-way flights from St. Louis to BuffaloSearch for one-way flight options from St. Louis to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from St. Louis to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/153:49 pm
STL
- BUF
1 stop17h 13m
Frontier
Deal found 2/1![Frontier logo]()
$142
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:15 pm
STL
- BUF
1 stop4h 58m
Delta
Deal found 2/3![Delta logo]()
$159
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:13 pm
STL
- BUF
1 stop15h 00m
Frontier
Deal found 2/2![Frontier logo]()
$165
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:00 am
STL
- BUF
1 stop4h 43m
American Airlines
Deal found 2/2![American Airlines logo]()
$194
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:00 am
STL
- BUF
2 stops8h 14m
United Airlines
Deal found 2/3![United Airlines logo]()
$199
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:15 pm
STL
- BUF
2 stops8h 00m
Southwest
Deal found 2/2![Southwest logo]()
$209
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:05 am
STL
- BUF
1 stop7h 20m
American Airlines
Deal found 2/2![American Airlines logo]()
$222
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/156:25 am
STL
- BUF
2 stops6h 48m
United Airlines
Deal found 2/1![United Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/29:50 am
STL
- BUF
3 stops31h 31m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:20 pm
STL
- BUF
3 stops46h 01m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$401
Find flight deals from St. Louis to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $204 (Kiwi.com) |
One-way from | $142 (Kiwi.com) |
Popular in | January |
Cheapest in | November |
Average price | $407 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from St. Louis to Buffalo that are best for you.
Fly from
St. Louis
Fly to
Buffalo
Route
Depart
Return
Price
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Fri 2/13
8:20 pm-5:45 pm
2 stops20h 25m
Buffalo
Sun 2/15
2:19 pm-6:51 am
1 stop17h 32m
$302
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Wed 4/15
4:55 pm-10:30 am
2 stops16h 35m
Buffalo
Sat 4/18
1:08 pm-10:30 am
1 stop22h 22m
$315
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Tue 6/16
1:13 pm-9:02 pm
1 stop6h 49m
Buffalo
Tue 6/23
7:00 am-12:11 pm
1 stop6h 11m
$317
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Wed 6/3
6:04 pm-11:59 pm
1 stop4h 55m
Buffalo
Sat 6/6
6:25 am-9:26 am
1 stop4h 01m
$342
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Wed 3/11
5:59 pm-10:55 pm
1 stop3h 56m
Buffalo
Mon 3/16
7:38 pm-11:58 pm
1 stop5h 20m
$342
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Wed 6/3
6:04 pm-11:59 pm
1 stop4h 55m
Buffalo
Mon 6/8
9:00 am-1:17 pm
1 stop5h 17m
$342
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Fri 3/6
1:09 pm-10:49 am
2 stops20h 40m
Buffalo
Sun 3/8
9:25 pm-7:02 am
1 stop10h 37m
$348
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Fri 3/6
6:35 am-11:43 am
1 stop4h 08m
Buffalo
Sun 3/8
6:15 am-9:46 am
1 stop4h 31m
$367
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Sun 2/15
3:49 pm-10:02 am
1 stop17h 13m
$142
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Wed 3/11
10:12 am-5:37 pm
1 stop6h 25m
$159
Showing 1-10 of 14 results
Compare providers for flights from St. Louis to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Buffalo in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from St. Louis with our price prediction graph.
STL-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Buffalo
How far ahead should I book a flight from St. Louis to Buffalo?
Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Buffalo. Price data was last updated on January 30, 2026.
To ensure you get the cheapest price possible for a flight from St. Louis to Buffalo, you should look to book at least 17 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to Buffalo?
Currently, March is the cheapest month in which you can book a flight from St. Louis to Buffalo (average of $136). Flying from St. Louis to Buffalo in April is currently the most expensive (average of $281). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated February 3, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from St. Louis to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 3, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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St. Louis and Buffalo flights
Browse other St. Louis and Buffalo flight options. Last updated on February 3, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on February 3, 2026.
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Top 4 airlines flying from St. Louis to Buffalo
Discover the top 4 airlines that operate flights from St. Louis to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$143 | Average$306 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$167 | Average$556 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$221 | Average$346 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$306 | Average$416 | FlexibilityNo cancel fee | On-time63% |