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$66+ Cheap flights from Spartanburg, SC to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BUF
Jan 30 — Feb 61
Fri 1/30
Fri 2/6
1 adult, Economy
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Cheapflights Tip: The best prices from Spartanburg to Buffalo are usually found in January or September, booked 87 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Spartanburg to Buffalo

Cheapest flights from Spartanburg to Buffalo
Explore the most affordable flight options available from Spartanburg to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:48 pmCLT - BUF
Nonstop1h 43mAmerican Airlines
Sun 1/46:00 amBUF - CLT
Nonstop2h 09mAmerican Airlines
Deal found 12/30$383
This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:05 pmCLT - BUF
1 stop6h 28mDelta
Sun 1/46:10 amBUF - CLT
1 stop6h 15mDelta
Deal found 12/30$403
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:48 pmCLT - BUF
Nonstop1h 43mAmerican Airlines
Mon 1/56:00 amBUF - CLT
Nonstop2h 09mAmerican Airlines
Deal found 12/29$446
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:02 amCLT - BUF
2 stops12h 31mUnited Airlines
Sun 1/41:59 pmBUF - CLT
1 stop7h 21mUnited Airlines
Deal found 12/28$461
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:25 pmCLT - BUF
Nonstop1h 34mAmerican Airlines
Sun 1/46:00 amBUF - CLT
Nonstop2h 09mAmerican Airlines
Deal found 12/28$464
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:48 pmCLT - BUF
Nonstop1h 43mAmerican Airlines
Thu 1/16:00 amBUF - CLT
Nonstop2h 09mAmerican Airlines
Deal found 12/30$479
This Southwest deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:20 pmCLT - BUF
1 stop3h 40mSouthwest
Sun 1/412:25 pmBUF - CLT
2 stops10h 25mSouthwest
Deal found 12/30$481
This Southwest deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:05 pmCLT - BUF
1 stop4h 00mSouthwest
Sun 1/411:15 amBUF - CLT
1 stop5h 45mSouthwest
Deal found 12/28$484
This Kiwi.com deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:24 pmCLT - BUF
1 stop23h 16mMultiple Airlines
Sun 1/41:37 pmBUF - CLT
2 stops9h 52mMultiple Airlines
Deal found 12/28$510

Find flight deals from Spartanburg to Buffalo

Keep the following information in mind while searching for Spartanburg to Buffalo flight deals. Data was last updated December 31, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$132
(Kiwi.com)

One-way from

$66
(Trip.com)

Popular in

December

Cheapest in

January

Average price

$384
Provider with most accurate pricing for Charlotte Douglas-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Buffalo flights.
Search Deals
From Spartanburg to Buffalo
Search Deals
One-way flight from Spartanburg to Buffalo
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Spartanburg to Buffalo that are best for you.

Fly from

Spartanburg

Fly to

Buffalo

Route

Depart

Return

Price

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Thu 1/22

11:12 am-7:04 pm

1 stop7h 52m

Buffalo

Fri 1/23

7:31 pm-9:55 am

1 stop14h 24m

$149

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Wed 1/21

9:07 pm-7:04 pm

2 stops21h 57m

Buffalo

Sun 1/25

11:02 am-10:17 am

1 stop23h 15m

$169

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Fri 1/30

9:59 pm-11:34 am

1 stop13h 35m

Buffalo

Sun 2/1

11:02 am-12:40 am

2 stops13h 38m

$205

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Sun 2/15

3:17 pm-10:02 am

1 stop18h 45m

Buffalo

Sun 2/22

6:07 pm-8:26 am

2 stops38h 19m

$248

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Tue 2/3

11:05 am-3:10 pm

1 stop4h 05m

Buffalo

Tue 2/10

3:45 pm-7:55 pm

1 stop4h 10m

$273

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Tue 5/19

6:00 am-11:40 am

1 stop5h 40m

Buffalo

Sat 5/23

7:00 am-1:52 pm

1 stop6h 52m

$273

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Wed 5/20

11:25 am-5:23 pm

1 stop5h 58m

Buffalo

Tue 5/26

6:16 am-11:09 am

1 stop4h 53m

$273

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Sat 2/7

6:01 pm-10:07 am

1 stop16h 06m

$66

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Thu 1/29

9:58 pm-6:36 pm

1 stop20h 38m

$79

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

Sun 3/8

7:48 pm-8:30 pm

1 stop24h 42m

$114

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/31

Showing 1-10 of 19 results
1
2

Best time to book a flight from Spartanburg to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Buffalo

How far ahead should I book a flight from Spartanburg to Buffalo?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Buffalo. Price data was last updated on December 26, 2025.

Booking 87 days in advance of your planned departure date is, on average, the best time to get cheap flights from Spartanburg to Buffalo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Spartanburg to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Spartanburg to Buffalo (average of $39). Flying from Spartanburg to Buffalo in April is currently the most expensive (average of $160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to BUF?

Find hourly flight availability from Spartanburg to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 31, 2025.

It’s optimal to fly from Spartanburg to Buffalo in the morning. By choosing this option you can save up to 20% on the cost of your flight, compared to a flight in the evening.

What is the cheapest day to fly from Spartanburg to Buffalo?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to Buffalo. Price data was last updated on December 27, 2025.

Travelers seeking maximum savings on their Spartanburg to Buffalo flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated December 31, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Spartanburg to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,250 reviews

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,250 reviews
Southwest
8.0
Very good
4,250 reviews

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,012 reviews
Southwest
8.0
Very good
4,250 reviews

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,069 reviews
Southwest
8.0
Very good
4,250 reviews

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.7
Fair
3,067 reviews
Southwest
8.0
Very good
4,250 reviews

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Spartanburg?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly into when you book flights from Spartanburg to Buffalo. 5 airlines have flights to Buffalo from Spartanburg on a regular basis. Booking flights from Spartanburg to Buffalo should not be difficult; the airport handles an average of 0 inbound flights from Spartanburg per day.

  • How popular is this Spartanburg to Buffalo flight route?

    Within the past month, 5 users have taken a look at flights from Spartanburg to Buffalo.

  • What are the cheapest airlines to fly from Spartanburg to Buffalo one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $80. Users have also found prices from $108 and $113 on American Airlines and Southwest, respectively.

  • What are the cheapest flights from Spartanburg to Buffalo?

    While on average a flight from Spartanburg to Buffalo is generally $381, our data shows the cheapest flight currently is $253. When looking at the most popular route, (Charlotte Douglas - Buffalo), you can expect to pay $175 for that flight.

  • Can I find deals for flights from Spartanburg to Buffalo that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Buffalo.

  • Can I find deals for business class flights from Spartanburg to Buffalo?

    Yes. Cheapflights offers flight deals from Spartanburg to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Spartanburg to Buffalo (average of $39). Flying from Spartanburg to Buffalo in April is currently the most expensive (average of $160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from Spartanburg to Buffalo

Discover the top 5 airlines that operate flights from Spartanburg to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$68Average$198FlexibilityNo cancel feeOn-time62%
DeltaCheapest$191Average$300FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$192Average$376FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$207Average$335FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$344FlexibilityNo cancel feeOn-time69%

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