How long is the flight from Panama City, Florida to Buffalo?

American Airlines, Southwest, and United Airlines can get you from Panama City, Florida to Buffalo in just under 4h 32m. Your travel time can differ by up to 8h 27m. Panama City, Florida and Buffalo are separated by a distance of 952 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from Panama City, Florida to Buffalo round-trip?

Flying on American Airlines is currently your cheapest option to Buffalo, with prices starting at $172. Another option worth looking into is Delta, starting at $290 round trip. You may be able to fly from Panama City, Florida to Buffalo for 58% less than the average price by searching for these airlines.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Most accurate provider : When it comes to deals on Panama City, Florida-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City, Florida-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Buffalo flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Panama City, Florida-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Panama City to Buffalo that include hotel bookings?

Yes. In addition to deals on Panama City to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Buffalo.

Can I find deals for business class flights from Panama City to Buffalo?

Yes. Cheapflights offers flight deals from Panama City to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$194+ Flights from Panama City, FL to Buffalo

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Cheap flight deals from Panama City to Buffalo

Best flights from Panama City to Buffalo
Discover carefully curated flight deals from Panama City to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated dezembro 12, 2025.

seg 3/97:19 amECP - BUF

1 stop4h 32mAmerican Airlines

qui 3/127:40 pmBUF - ECP

1 stop5h 09mAmerican Airlines

Deal found 12/10

$387

seg 3/92:45 pmECP - BUF

2 stops8h 25mSouthwest

qui 3/1212:05 pmBUF - ECP

1 stop6h 15mSouthwest

Deal found 12/10

$392

qua 1/146:30 amECP - BUF

2 stops12h 59mUnited Airlines

dom 1/188:30 amBUF - ECP

2 stops8h 42mUnited Airlines

Deal found 12/11

$439

seg 3/91:00 pmECP - BUF

3 stops26h 42mUnited Airlines

qui 3/127:00 amBUF - ECP

2 stops10h 11mUnited Airlines

Deal found 12/10

$780

Last-minute flights from Panama City to Buffalo
Discover last-minute flight deals from Panama City to Buffalo. Data last updated dezembro 12, 2025 and is based on user searches.

qua 1/146:30 amECP - BUF

2 stops12h 59mUnited Airlines

dom 1/188:30 amBUF - ECP

2 stops8h 42mUnited Airlines

Deal found 12/11

$439

One-way flights from Panama City to Buffalo
Search for one-way flight options from Panama City to Buffalo. Find affordable one-way fares based on user searches. Data last updated dezembro 12, 2025.

seg 3/168:05 amECP - BUF

1 stop6h 54mDelta

Deal found 12/11

$194

dom 4/128:05 amECP - BUF

1 stop6h 54mDelta

Deal found 12/11

$299

seg 4/137:45 amECP - BUF

2 stops8h 38mDelta

Deal found 12/11

$305

dom 4/125:35 amECP - BUF

2 stops7h 40mSouthwest

Deal found 12/11

$306

sáb 4/118:05 amECP - BUF

1 stop6h 54mDelta

Deal found 12/11

$330

seg 3/165:03 pmECP - BUF

3 stops26h 43mUnited Airlines

Deal found 12/11

$428

Find flight deals from Panama City to Buffalo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$387 (American Airlines)
One-way from	$194 (Delta)
Popular in	January
Cheapest in	September
Average price	$584

Provider with most accurate pricing for Panama City NW Florida Beaches-Buffalo flight deals.

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Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Buffalo flights.

Search Deals

From Panama City NW Florida Beaches to Buffalo

Search Deals

One-way flight from Panama City NW Florida Beaches to Buffalo

Search Deals

Highest demand for flights based on searches. 23% potential increase in price ($125 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($23 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

seg 3/9

7:19 am-12:51 pm

1 stop4h 32m

Buffalo

qui 3/12

7:40 pm-11:49 pm

1 stop5h 09m

$387

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

seg 3/9

2:45 pm-12:10 am

2 stops8h 25m

Buffalo

qui 3/12

12:05 pm-5:20 pm

1 stop6h 15m

$392

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

qua 1/14

6:30 am-8:29 pm

2 stops12h 59m

Buffalo

dom 1/18

8:30 am-4:12 pm

2 stops8h 42m

$439

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

seg 3/9

1:00 pm-4:42 pm

3 stops26h 42m

Buffalo

qui 3/12

7:00 am-4:11 pm

2 stops10h 11m

$780

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

seg 3/16

8:05 am-3:59 pm

1 stop6h 54m

$194

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

dom 4/12

8:05 am-3:59 pm

1 stop6h 54m

$299

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

seg 4/13

7:45 am-5:23 pm

2 stops8h 38m

$305

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

dom 4/12

5:35 am-2:15 pm

2 stops7h 40m

$306

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

sáb 4/11

8:05 am-3:59 pm

1 stop6h 54m

$330

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

seg 3/16

5:03 pm-8:46 pm

3 stops26h 43m

$428

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Compare providers for flights from Panama City to Buffalo

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Buffalo in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Panama City, Florida-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City, Florida-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Buffalo flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Panama City, Florida-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Buffalo

What is the cheapest month to book a flight from Panama City, Florida to Buffalo?

Currently, December is the cheapest month in which you can book a flight from Panama City, Florida to Buffalo (average of $128). Flying from Panama City, Florida to Buffalo in February is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to BUF?

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Buffalo in the evening. If you’re flexible enough to do this you can expect to save up to 21% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Buffalo

Read reviews from past customers who have flown Delta and American Airlines from Panama City to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Delta

7.9

Good

8,007 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

American Airlines

7.2

Good

11,050 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

How long is the flight from Panama City, Florida to Buffalo?
American Airlines, Southwest, and United Airlines can get you from Panama City, Florida to Buffalo in just under 4h 32m. Your travel time can differ by up to 8h 27m. Panama City, Florida and Buffalo are separated by a distance of 952 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from Panama City, Florida to Buffalo round-trip?
Flying on American Airlines is currently your cheapest option to Buffalo, with prices starting at $172. Another option worth looking into is Delta, starting at $290 round trip. You may be able to fly from Panama City, Florida to Buffalo for 58% less than the average price by searching for these airlines.
Can I find deals for flights from Panama City to Buffalo that include hotel bookings?
Yes. In addition to deals on Panama City to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Buffalo.
Can I find deals for business class flights from Panama City to Buffalo?
Yes. Cheapflights offers flight deals from Panama City to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City, Florida to Buffalo?
Currently, December is the cheapest month in which you can book a flight from Panama City, Florida to Buffalo (average of $128). Flying from Panama City, Florida to Buffalo in February is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Panama City to Buffalo

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$172	Average$344	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$290	Average$366	FlexibilityNo cancel fee	On-timeN/A

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$194+ Cheap flights from Panama City, FL to Buffalo (ECP - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Buffalo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to Buffalo

Best flights from Panama City to BuffaloDiscover carefully curated flight deals from Panama City to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated dezembro 12, 2025.

Discover carefully curated flight deals from Panama City to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated dezembro 12, 2025.

Find flight deals from Panama City to Buffalo

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Buffalo that are best for you.

Compare providers for flights from Panama City to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Buffalo in December.

Best time to book a flight from Panama City to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Buffalo

What is the cheapest month to book a flight from Panama City, Florida to Buffalo?

What is the cheapest time of day to fly from ECP to BUF?

Reviews of airlines servicing Buffalo

Read reviews from past customers who have flown Delta and American Airlines from Panama City to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Panama City, Florida to Buffalo?

What are the cheapest airlines flying from Panama City, Florida to Buffalo round-trip?

Can I find deals for flights from Panama City to Buffalo that include hotel bookings?

How can I find direct flights from Panama City to Buffalo?

Can I find deals for business class flights from Panama City to Buffalo?

What is the cheapest month to book a flight from Panama City, Florida to Buffalo?

Traveling to a place near Buffalo?

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Alternative routes for Panama City to Buffalo

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Top 2 airlines flying from Panama City to Buffalo

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Best flights from Panama City to Buffalo
Discover carefully curated flight deals from Panama City to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated dezembro 12, 2025.