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$159+ Cheap flights from Panama City, FL to Buffalo (ECP - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — BUF
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Panama City to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2025.

Round-trip from

$237
(Delta)

One-way from

$159
(American Airlines)

Popular in

April

Cheapest in

September

Average price

$342
From Panama City NW Florida Beaches to Buffalo
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One-way flight from Panama City NW Florida Beaches to Buffalo
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Highest demand for flights based on searches. 6% potential increase in price ($25 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Panama City to Buffalo

Cheapest flights from Panama City to Buffalo
Explore the most affordable flight options available from Panama City to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/276:00 amECP - BUF
1 stop3h 57mDelta
Wed 9/35:10 pmBUF - ECP
1 stop6h 56mDelta
Deal found 7/30$237
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/271:44 pmECP - BUF
1 stop6h 32mUnited Airlines
Wed 9/37:05 amBUF - ECP
2 stops10h 15mUnited Airlines
Deal found 7/30$242
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2710:18 amECP - BUF
2 stops7h 16mAmerican Airlines
Wed 9/36:00 amBUF - ECP
2 stops9h 20mAmerican Airlines
Deal found 7/30$247
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/157:25 amECP - BUF
1 stop5h 25mSouthwest
Wed 8/2012:50 pmBUF - ECP
2 stops7h 00mSouthwest
Deal found 7/30$337

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Panama City to Buffalo that are best for you.

Fly from

Panama City

Fly to

Buffalo

Route

Depart

Return

Price

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Wed 8/27

6:00 am-10:57 am

1 stop3h 57m

Buffalo

Wed 9/3

5:10 pm-11:06 pm

1 stop6h 56m

$237

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Wed 8/27

1:44 pm-9:16 pm

1 stop6h 32m

Buffalo

Wed 9/3

7:05 am-4:20 pm

2 stops10h 15m

$242

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Wed 8/27

10:18 am-6:34 pm

2 stops7h 16m

Buffalo

Wed 9/3

6:00 am-2:20 pm

2 stops9h 20m

$247

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 8/15

7:25 am-1:50 pm

1 stop5h 25m

Buffalo

Wed 8/20

12:50 pm-6:50 pm

2 stops7h 00m

$337

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 9/12

3:29 pm-11:55 pm

1 stop7h 26m

$159

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 9/12

11:09 am-11:59 pm

2 stops11h 50m

$198

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Mon 8/18

6:00 am-10:57 am

1 stop3h 57m

$214

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Sun 8/17

12:55 pm-11:30 pm

2 stops9h 35m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Panama City to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Buffalo

What is the cheapest month to book a flight from Panama City, Florida to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Buffalo (average of $256). Flying from Panama City, Florida to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to BUF?

Find hourly flight availability from Panama City to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Buffalo in the morning. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated July 30, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Panama City to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,980 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City, Florida to Buffalo round-trip?

    Flying on Delta is currently your cheapest option to Buffalo, with prices starting at $237. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $242 and $247, respectively. You may be able to fly from Panama City, Florida to Buffalo for 37% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Panama City, Florida to Buffalo one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $159. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from Panama City, Florida to Buffalo for a low price.

  • Can I find deals for flights from Panama City to Buffalo that include hotel bookings?

    Yes. In addition to deals on Panama City to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Buffalo.

  • Can I find deals for business class flights from Panama City to Buffalo?

    Yes. Cheapflights offers flight deals from Panama City to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Buffalo (average of $256). Flying from Panama City, Florida to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Top 2 airlines flying from Panama City to Buffalo

Discover the top 2 airlines that operate flights from Panama City to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$172Average$318FlexibilityNo cancel feeOn-time71%
DeltaCheapest$286Average$356FlexibilityNo cancel feeOn-timeN/A

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