HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Buffalo

$109+ Cheap flights from Panama City, FL to Buffalo (ECP - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — BUF
Jun 20 — Jun 271
Fri 6/20
Fri 6/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Buffalo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 15, 2025.

Round-trip from

$217
(Delta)

One-way from

$109
(American Airlines)

Popular in

April

Cheapest in

September

Average price

$344
From Panama City NW Florida Beaches to Buffalo
Search Deals
One-way flight from Panama City NW Florida Beaches to Buffalo
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($19 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Panama City to Buffalo

Cheapest flights from Panama City to Buffalo
Explore the most affordable flight options available from Panama City to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2025.

This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/46:00 amECP - BUF
1 stop4h 02mDelta
Mon 8/117:15 pmBUF - ECP
1 stop4h 51mDelta
Deal found 6/13$217
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/147:06 pmECP - BUF
1 stop4h 03mAmerican Airlines
Mon 8/1810:04 amBUF - ECP
2 stops8h 26mAmerican Airlines
Deal found 6/13$247
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1311:10 amECP - BUF
2 stops11h 28mUnited Airlines
Wed 8/207:05 amBUF - ECP
2 stops10h 15mUnited Airlines
Deal found 6/12$351
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/411:10 amECP - BUF
2 stops7h 55mSouthwest
Sun 7/68:50 amBUF - ECP
2 stops8h 45mSouthwest
Deal found 6/12$490

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2025.
Use the filters below to find and compare flights from Panama City to Buffalo that are best for you.

Fly from

Panama City

Fly to

Buffalo

Route

Depart

Return

Price

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Mon 8/4

6:00 am-11:02 am

1 stop4h 02m

Buffalo

Mon 8/11

7:15 pm-11:06 pm

1 stop4h 51m

$217

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Thu 8/14

7:06 pm-12:09 am

1 stop4h 03m

Buffalo

Mon 8/18

10:04 am-5:30 pm

2 stops8h 26m

$247

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Wed 8/13

11:10 am-11:38 pm

2 stops11h 28m

Buffalo

Tue 8/19

10:30 am-8:16 pm

2 stops10h 46m

$351

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 7/4

11:10 am-8:05 pm

2 stops7h 55m

Buffalo

Sun 7/6

8:50 am-4:35 pm

2 stops8h 45m

$490

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Thu 9/4

3:29 pm-11:50 pm

1 stop7h 21m

$109

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 6/27

4:55 pm-11:51 pm

1 stop5h 56m

$214

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Fri 6/27

8:40 am-11:39 pm

2 stops13h 59m

$262

Panama CityBuffalo

ECP - BUF

ECPBUF

Panama City NW Florida Beaches

Sat 6/28

6:05 am-3:45 pm

2 stops8h 40m

$267

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/14

Best time to book a flight from Panama City to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Buffalo

What is the cheapest month to book a flight from Panama City, Florida to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Buffalo (average of $256). Flying from Panama City, Florida to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to BUF?

Find hourly flight availability from Panama City to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 15, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Buffalo in the morning. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight at noon.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated June 15, 2025.
See what other customers who have flown with Southwest, Delta and United Airlines from Panama City to Buffalo have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,285 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,285 reviews
Southwest
8.0
Very good
4,285 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,961 reviews
Southwest
8.0
Very good
4,285 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,798 reviews
Southwest
8.0
Very good
4,285 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,285 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Crew

8.6

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City, Florida to Buffalo round-trip?

    Flying on Delta is currently your cheapest option to Buffalo, with prices starting at $217. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $247 and $351, respectively. You may be able to fly from Panama City, Florida to Buffalo for 43% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Panama City, Florida to Buffalo one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $109. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Panama City, Florida to Buffalo for a low price.

  • Can I find deals for flights from Panama City to Buffalo that include hotel bookings?

    Yes. In addition to deals on Panama City to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Buffalo.

  • Can I find deals for business class flights from Panama City to Buffalo?

    Yes. Cheapflights offers flight deals from Panama City to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Buffalo (average of $256). Flying from Panama City, Florida to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Williamsville
Amherst
Orchard Park
Batavia
Eden
Cheektowaga
West Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
Miami to John F Kennedy Intl flights
Fort Lauderdale to LaGuardia flights
Fort Lauderdale to Newark flights
Miami to Newark flights
Orlando to John F Kennedy Intl flights
Miami to LaGuardia flights
Orlando to LaGuardia flights
Fort Lauderdale to John F Kennedy Intl flights
Orlando to Newark flights
Tampa to Newark flights
Tampa to John F Kennedy Intl flights
West Palm Beach to John F Kennedy Intl flights
Tampa to LaGuardia flights
Jacksonville to John F Kennedy Intl flights
West Palm Beach to LaGuardia flights
West Palm Beach to Newark flights
Orlando to Islip flights
Jacksonville to LaGuardia flights
Jacksonville to Newark flights
Sarasota to LaGuardia flights
Orlando to White Plains flights
Fort Myers to John F Kennedy Intl flights
Sarasota to Newark flights
Fort Myers to Newark flights
Orlando to Buffalo flights
Orlando to Albany flights
Sarasota to John F Kennedy Intl flights
Fort Myers to LaGuardia flights
West Palm Beach to Islip flights
Orlando to Stewart flights
Fort Lauderdale to Buffalo flights
West Palm Beach to White Plains flights
Tampa to Islip flights
Orlando to Syracuse flights
Tampa to White Plains flights
Pensacola to LaGuardia flights
Pensacola to John F Kennedy Intl flights
Orlando Sanford Intl to Newark flights
Fort Lauderdale to Albany flights
Tampa to Albany flights
Tampa to Buffalo flights
Fort Lauderdale to White Plains flights
Fort Lauderdale to Stewart flights
Tampa to Stewart flights
Pensacola to Newark flights
Daytona Beach to White Plains flights
Miami to Buffalo flights
West Palm Beach to Syracuse flights
Panama City to LaGuardia flights
Tallahassee to John F Kennedy Intl flights

Top 2 airlines flying from Panama City to Buffalo

Discover the top 2 airlines that operate flights from Panama City to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$172Average$366FlexibilityNo cancel feeOn-time71%
DeltaCheapest$286Average$366FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.