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$261+ Cheap flights from Medford to Buffalo (MFR - BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — BUF
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Medford to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$261
(Delta)
From Medford to Buffalo
Search Deals

Find flight deals from Medford to Buffalo

Cheapest flights from Medford to Buffalo
Explore the most affordable flight options available from Medford to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:00 amMFR - BUF
2 stops14h 50mDelta
Sat 11/112:49 pmBUF - MFR
2 stops12h 46mDelta
Deal found 7/27$261
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:30 amMFR - BUF
2 stops13h 23mAmerican Airlines
Mon 9/151:00 pmBUF - MFR
2 stops13h 00mAmerican Airlines
Deal found 7/29$319
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/51:03 pmMFR - BUF
1 stop6h 53mUnited Airlines
Mon 9/1510:55 amBUF - MFR
2 stops13h 09mUnited Airlines
Deal found 7/29$329

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Medford to Buffalo that are best for you.

Fly from

Medford

Fly to

Buffalo

Route

Depart

Return

Price

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Tue 10/28

6:00 am-11:50 pm

2 stops14h 50m

Buffalo

Sat 11/1

12:49 pm-10:35 pm

2 stops12h 46m

$261

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Fri 9/5

5:30 am-9:53 pm

2 stops13h 23m

Buffalo

Mon 9/15

1:00 pm-11:00 pm

2 stops13h 00m

$319

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Fri 9/5

1:03 pm-10:56 pm

1 stop6h 53m

Buffalo

Mon 9/15

10:55 am-9:04 pm

2 stops13h 09m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from Medford to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated July 29, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Medford to Buffalo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Medford to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Medford to Buffalo round-trip?

    Delta, at $261, was found to be the cheapest airline from Medford to Buffalo.Alternate airlines to your destination round-trip include American Airlines and United Airlines.

  • Can I find deals for flights from Medford to Buffalo that include hotel bookings?

    Yes. In addition to deals on Medford to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Buffalo.

  • Can I find deals for business class flights from Medford to Buffalo?

    Yes. Cheapflights offers flight deals from Medford to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Medford to Buffalo (average of $256). Flying from Medford to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Top airline flying from Medford to Buffalo

Discover the top airline that operate flights from Medford to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$368Average$603FlexibilityNo cancel feeOn-time69%

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