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$261+ Cheap flights from Medford to Buffalo (MFR - BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — BUF
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Medford to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$261
(Delta)
From Medford to Buffalo
Search Deals

Find flight deals from Medford to Buffalo

Cheapest flights from Medford to Buffalo
Explore the most affordable flight options available from Medford to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:00 amMFR - BUF
2 stops14h 43mDelta
Sat 11/112:38 pmBUF - MFR
2 stops13h 12mDelta
Deal found 9/10$261
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:23 pmMFR - BUF
2 stops14h 37mDelta
Thu 11/276:00 amBUF - MFR
2 stops16h 05mDelta
Deal found 9/11$315
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:36 pmMFR - BUF
2 stops12h 12mUnited Airlines
Sat 11/18:04 amBUF - MFR
1 stop8h 19mUnited Airlines
Deal found 9/9$504
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:00 amMFR - BUF
2 stops13h 00mUnited Airlines
Thu 11/278:04 amBUF - MFR
3 stops41h 26mUnited Airlines
Deal found 9/11$562
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/125:24 pmMFR - BUF
2 stops14h 07mDelta
Sat 10/186:00 amBUF - MFR
2 stops13h 44mDelta
Deal found 9/10$918
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/125:00 amMFR - BUF
1 stop14h 46mUnited Airlines
Sat 10/188:25 amBUF - MFR
1 stop7h 46mUnited Airlines
Deal found 9/10$933

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Medford to Buffalo that are best for you.

Fly from

Medford

Fly to

Buffalo

Route

Depart

Return

Price

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Tue 10/28

6:00 am-11:43 pm

2 stops14h 43m

Buffalo

Sat 11/1

12:38 pm-10:50 pm

2 stops13h 12m

$261

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Tue 11/18

5:30 am-5:07 pm

2 stops8h 37m

Buffalo

Thu 11/27

6:00 am-7:05 pm

2 stops16h 05m

$315

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Tue 10/28

6:36 pm-9:48 am

2 stops12h 12m

Buffalo

Sat 11/1

8:04 am-1:23 pm

1 stop8h 19m

$504

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Tue 11/18

5:00 am-9:00 pm

2 stops13h 00m

Buffalo

Thu 11/27

8:04 am-10:30 pm

3 stops41h 26m

$562

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Medford to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated September 11, 2025.
See what other customers who have flown with United Airlines from Medford to Buffalo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Medford to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Medford to Buffalo?

    For as low as $504, Delta can have you in Buffalo from Medford in 12h 12m. There are 2216 mi between Medford and Buffalo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Medford to Buffalo round-trip?

    United Airlines, at $285, was found to be the cheapest airline from Medford to Buffalo..

  • Can I find deals for flights from Medford to Buffalo that include hotel bookings?

    Yes. In addition to deals on Medford to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Buffalo.

  • Can I find deals for business class flights from Medford to Buffalo?

    Yes. Cheapflights offers flight deals from Medford to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Medford to Buffalo (average of $256). Flying from Medford to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Top airline flying from Medford to Buffalo

Discover the top airline that operate flights from Medford to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$285Average$603FlexibilityNo cancel feeOn-time69%

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