What are the most popular routes from Iowa to Buffalo?

While some choose either Omaha Eppley Airfield - Buffalo or Cedar Rapids - Buffalo, Des Moines - Buffalo is the most popular route from Iowa to Buffalo.

What are the most popular airlines that fly from Iowa to Buffalo?

When booking a flight from Iowa to Buffalo, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What is the cheapest month to fly from Iowa to Buffalo?

The best pricing can be found in the month of November. Prices to Buffalo from Iowa average $462. You can even find prices in November for less than $462, as users have found deals to Buffalo from as low as $276. The month of December appears to be one of the more expensive times to travel to Buffalo from Iowa. Flying in the targeted month can save you up to 54%.

What is the cheapest time of day to fly from IA to BUF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Iowa to Buffalo as you normally would.

What airport do you fly into for flights to Buffalo from Iowa?

Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Iowa. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

Can I find deals for flights from Iowa to Buffalo that include hotel bookings?

Yes. In addition to deals on Iowa to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Iowa to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Buffalo.

Can I find deals for business class flights from Iowa to Buffalo?

Yes. Cheapflights offers flight deals from Iowa to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$149+ Flights from Iowa to Buffalo - Compare & Save Big

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Cheap flight deals from Iowa to Buffalo

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$233 (Delta)
One-way from	$149 (Delta)
Popular in	December
Cheapest in	November
Average price	$379

Provider with most accurate pricing for Des Moines-Buffalo flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Buffalo flights.

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From Iowa to Buffalo

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One-way flight from Iowa to Buffalo

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Highest demand for flights based on searches. 10% potential increase in price ($53 potential increase over avg. RT price).

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Cheapest flight prices on average. 5% potential price decrease ($26 potential savings vs. average RT price).

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Average for round-trip flights in May 2025

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Find flight deals from Iowa to Buffalo

Cheapest flights from Iowa to Buffalo
Explore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Wed 5/285:15 pmMLI - BUF

1 stop5h 40mDelta

Wed 6/46:35 pmBUF - MLI

1 stop5h 22mDelta

Deal found 4/29

$233

Thu 8/218:00 amCID - BUF

1 stop4h 22mUnited Airlines

Wed 8/275:54 pmBUF - CID

1 stop4h 36mUnited Airlines

Deal found 5/1

$249

Sat 7/193:06 pmALO - BUF

1 stop6h 43mAmerican Airlines

Sat 7/266:00 amBUF - ALO

2 stops9h 36mAmerican Airlines

Deal found 5/1

$254

Sat 6/76:34 pmMLI - BUF

1 stop3h 55mAmerican Airlines

Tue 6/105:06 pmBUF - MLI

2 stops7h 36mAmerican Airlines

Deal found 5/1

$254

Thu 8/217:00 amCID - BUF

2 stops7h 42mDelta

Wed 8/2712:50 pmBUF - CID

2 stops10h 00mDelta

Deal found 5/1

$259

Tue 6/1010:39 amOMA - BUF

1 stop7h 02mDelta

Wed 6/187:46 pmBUF - OMA

1 stop5h 39mDelta

Deal found 4/30

$271

Tue 7/1511:24 amDSM - BUF

1 stop6h 16mDelta

Tue 7/222:18 pmBUF - DSM

1 stop5h 59mDelta

Deal found 5/1

$271

Wed 5/286:14 pmOMA - BUF

1 stop5h 00mAmerican Airlines

Wed 6/43:50 pmBUF - OMA

2 stops7h 47mAmerican Airlines

Deal found 4/29

$276

Wed 5/214:00 pmOMA - BUF

1 stop4h 05mSouthwest

Wed 5/282:55 pmBUF - OMA

2 stops8h 20mSouthwest

Deal found 5/1

$310

Tue 6/103:23 pmOMA - BUF

1 stop4h 38mUnited Airlines

Tue 6/1710:28 amBUF - OMA

2 stops8h 06mUnited Airlines

Deal found 4/30

$346

Tue 7/156:24 amDSM - BUF

2 stops11h 32mUnited Airlines

Wed 7/235:54 pmBUF - DSM

1 stop6h 06mUnited Airlines

Deal found 5/1

$346

Wed 5/2810:55 amMLI - BUF

2 stops11h 49mUnited Airlines

Wed 6/46:15 amBUF - MLI

2 stops11h 33mUnited Airlines

Deal found 4/29

$354

Best flights from Iowa to Buffalo
Discover carefully curated flight deals from Iowa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2025.

Wed 5/285:15 pmMLI - BUF

1 stop5h 40mDelta

Wed 6/46:35 pmBUF - MLI

1 stop5h 22mDelta

Deal found 4/29

$233

Thu 8/218:00 amCID - BUF

1 stop4h 22mUnited Airlines

Wed 8/275:54 pmBUF - CID

1 stop4h 36mUnited Airlines

Deal found 5/1

$249

Sat 6/76:34 pmMLI - BUF

1 stop3h 55mAmerican Airlines

Tue 6/105:06 pmBUF - MLI

2 stops7h 36mAmerican Airlines

Deal found 5/1

$254

Wed 5/214:00 pmOMA - BUF

1 stop4h 05mSouthwest

Wed 5/282:55 pmBUF - OMA

2 stops8h 20mSouthwest

Deal found 5/1

$310

Thu 8/217:00 amCID - BUF

2 stops7h 42mDelta

Wed 8/2712:50 pmBUF - CID

2 stops10h 00mDelta

Deal found 5/1

$259

Wed 5/286:14 pmOMA - BUF

1 stop5h 00mAmerican Airlines

Wed 6/43:50 pmBUF - OMA

2 stops7h 47mAmerican Airlines

Deal found 4/29

$276

Tue 7/1511:24 amDSM - BUF

1 stop6h 16mDelta

Tue 7/222:18 pmBUF - DSM

1 stop5h 59mDelta

Deal found 5/1

$271

Wed 5/215:03 pmOMA - BUF

1 stop5h 10mDelta

Wed 5/2810:50 amBUF - OMA

1 stop6h 30mDelta

Deal found 5/1

$271

Tue 7/156:24 amDSM - BUF

2 stops11h 32mUnited Airlines

Wed 7/235:54 pmBUF - DSM

1 stop6h 06mUnited Airlines

Deal found 5/1

$346

Thu 8/76:12 pmDSM - BUF

1 stop4h 57mAmerican Airlines

Sun 8/106:30 amBUF - DSM

1 stop7h 22mAmerican Airlines

Deal found 4/29

$335

Wed 6/1111:28 amOMA - BUF

2 stops11h 16mUnited Airlines

Tue 6/171:57 pmBUF - OMA

1 stop4h 37mUnited Airlines

Deal found 4/30

$346

Thu 8/75:30 pmDSM - BUF

2 stops13h 25mSouthwest

Sun 8/106:00 amBUF - DSM

2 stops6h 20mSouthwest

Deal found 4/29

$425

Last-minute flights from Iowa to Buffalo
Discover last-minute flight deals from Iowa to Buffalo. Data last updated May 1, 2025 and is based on user searches.

Wed 5/143:28 pmOMA - BUF

1 stop4h 54mUnited Airlines

Wed 5/215:57 pmBUF - OMA

1 stop4h 26mUnited Airlines

Deal found 4/30

$349

Fri 5/162:00 pmCID - BUF

1 stop5h 18mAmerican Airlines

Tue 5/206:00 pmBUF - CID

1 stop6h 44mAmerican Airlines

Deal found 4/30

$377

Fri 5/162:39 pmCID - BUF

1 stop5h 43mUnited Airlines

Tue 5/205:57 pmBUF - CID

1 stop4h 42mUnited Airlines

Deal found 4/30

$394

Fri 5/164:36 pmLSE - BUF

1 stop5h 46mAmerican Airlines

Tue 5/205:10 amBUF - LSE

1 stop7h 09mAmerican Airlines

Deal found 4/30

$484

Wed 5/215:03 pmOMA - BUF

1 stop5h 10mDelta

Wed 5/2810:50 amBUF - OMA

1 stop6h 30mDelta

Deal found 5/1

$271

Wed 5/214:00 pmOMA - BUF

1 stop4h 05mSouthwest

Wed 5/282:55 pmBUF - OMA

2 stops8h 20mSouthwest

Deal found 5/1

$310

Sat 5/2411:21 amDSM - BUF

2 stops11h 25mUnited Airlines

Sun 5/256:15 amBUF - DSM

2 stops9h 30mUnited Airlines

Deal found 5/1

$351

Tue 5/274:18 pmDSM - BUF

1 stop5h 55mDelta

Sat 5/3112:20 pmBUF - DSM

1 stop6h 30mDelta

Deal found 5/1

$284

Wed 5/285:15 pmMLI - BUF

1 stop5h 40mDelta

Wed 6/46:35 pmBUF - MLI

1 stop5h 22mDelta

Deal found 4/29

$233

Wed 5/286:14 pmOMA - BUF

1 stop5h 00mAmerican Airlines

Wed 6/43:50 pmBUF - OMA

2 stops7h 47mAmerican Airlines

Deal found 4/29

$276

Wed 5/2810:55 amMLI - BUF

2 stops11h 49mUnited Airlines

Wed 6/46:15 amBUF - MLI

2 stops11h 33mUnited Airlines

Deal found 4/29

$354

One-way flights from Iowa to Buffalo
Search for one-way flight options from Iowa to Buffalo. Find affordable one-way fares based on user searches. Data last updated May 1, 2025.

Sat 7/122:55 pmOMA - BUF

1 stop8h 04mDelta

Deal found 4/29

$149

Sat 7/126:00 amOMA - BUF

2 stops9h 55mUnited Airlines

Deal found 4/29

$189

Tue 5/203:26 pmSUX - BUF

2 stops28h 56mUnited Airlines

Deal found 4/30

$321

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Wed 5/28

5:15 pm-11:55 pm

1 stop5h 40m

Buffalo

Wed 6/4

6:35 pm-10:57 pm

1 stop5h 22m

$233

Cedar RapidsBuffalo

CID - BUF

CIDBUF

Cedar Rapids

Thu 8/21

8:00 am-1:22 pm

1 stop4h 22m

Buffalo

Wed 8/27

5:54 pm-9:30 pm

1 stop4h 36m

$249

WaterlooBuffalo

ALO - BUF

ALOBUF

Waterloo

Sat 7/19

3:06 pm-10:49 pm

1 stop6h 43m

Buffalo

Sat 7/26

6:00 am-2:36 pm

2 stops9h 36m

$254

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Sat 6/7

6:34 pm-11:29 pm

1 stop3h 55m

Buffalo

Tue 6/10

5:06 pm-11:42 pm

2 stops7h 36m

$254

Cedar RapidsBuffalo

CID - BUF

CIDBUF

Cedar Rapids

Thu 8/21

7:00 am-3:42 pm

2 stops7h 42m

Buffalo

Wed 8/27

12:50 pm-9:50 pm

2 stops10h 00m

$259

OmahaBuffalo

OMA - BUF

OMABUF

Omaha Eppley Airfield

Tue 6/10

10:39 am-6:41 pm

1 stop7h 02m

Buffalo

Wed 6/18

7:46 pm-12:25 am

1 stop5h 39m

$271

Des MoinesBuffalo

DSM - BUF

DSMBUF

Des Moines

Tue 7/15

11:24 am-6:40 pm

1 stop6h 16m

Buffalo

Tue 7/22

2:18 pm-7:17 pm

1 stop5h 59m

$271

OmahaBuffalo

OMA - BUF

OMABUF

Omaha Eppley Airfield

Wed 5/28

6:14 pm-12:14 am

1 stop5h 00m

Buffalo

Wed 6/4

3:50 pm-10:37 pm

2 stops7h 47m

$276

OmahaBuffalo

OMA - BUF

OMABUF

Omaha Eppley Airfield

Wed 5/21

4:00 pm-9:05 pm

1 stop4h 05m

Buffalo

Wed 5/28

2:55 pm-10:15 pm

2 stops8h 20m

$310

OmahaBuffalo

OMA - BUF

OMABUF

Omaha Eppley Airfield

Tue 6/10

3:23 pm-9:01 pm

1 stop4h 38m

Buffalo

Tue 6/17

10:28 am-5:34 pm

2 stops8h 06m

$346

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 19 results

Best time to book a flight from Iowa to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Iowa with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Buffalo

What is the cheapest month to book a flight from Iowa to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Iowa to Buffalo (average of $256). Flying from Iowa to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Buffalo by month

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

To help decide which airline to fly from Iowa to Buffalo, see what other customers have to say about Southwest, Delta and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,293 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Southwest

8.0

Very good

4,293 reviews

Southwest

8.0

Very good

4,293 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Delta

8.0

Very good

7,934 reviews

Southwest

8.0

Very good

4,293 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

United Airlines

7.4

Good

8,696 reviews

Southwest

8.0

Very good

4,293 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,293 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

What airport do you fly into for flights to Buffalo from Iowa?
Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Iowa. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.
What are the most popular routes from Iowa to Buffalo?
While some choose either Omaha Eppley Airfield - Buffalo or Cedar Rapids - Buffalo, Des Moines - Buffalo is the most popular route from Iowa to Buffalo.
Can I find deals for flights from Iowa to Buffalo that include hotel bookings?
Yes. In addition to deals on Iowa to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Iowa to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Buffalo.
Can I find deals for business class flights from Iowa to Buffalo?
Yes. Cheapflights offers flight deals from Iowa to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Iowa to Buffalo?
Currently, January is the cheapest month in which you can book a flight from Iowa to Buffalo (average of $256). Flying from Iowa to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Williamsville

Amherst

West Seneca

Batavia

Orchard Park

Cheektowaga

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Iowa to Buffalo

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$196	Average$346	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$228	Average$350	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$260	Average$465	FlexibilityNo cancel fee	On-time69%

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$149+ Cheap flights from Iowa to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Iowa to Buffalo with Cheapflights

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Cheap flight deals from Iowa to Buffalo

Keep the following information in mind while searching for Iowa to Buffalo flight deals. Data was last updated May 1, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Iowa to Buffalo

Cheapest flights from Iowa to BuffaloExplore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Explore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to Buffalo that are best for you.

Best time to book a flight from Iowa to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Iowa with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Buffalo

What is the cheapest month to book a flight from Iowa to Buffalo?

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated May 1, 2025.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Buffalo from Iowa?

What are the most popular routes from Iowa to Buffalo?

Can I find deals for flights from Iowa to Buffalo that include hotel bookings?

How can I find direct flights from Iowa to Buffalo?

Can I find deals for business class flights from Iowa to Buffalo?

What is the cheapest month to book a flight from Iowa to Buffalo?

Traveling to a place near Iowa?

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Alternative routes for Iowa to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Iowa to Buffalo

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Cheapest flights from Iowa to Buffalo
Explore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.