How long is the flight from Iowa to Buffalo?

Airlines like Delta, American Airlines, and United Airlines fly from Iowa to Buffalo in about 5h 25m. The time it takes to get you to your destination can typically vary by up to 5h. There are 611 mi between Iowa and Buffalo. This flight may include one or multiple stops.

What are the cheapest airlines to fly from Iowa to Buffalo one-way?

For one-way options, check prices for Delta. According to our data, you can fly for as low as $135. Users have also found prices from $148 and $151 on United Airlines and American Airlines, respectively.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

What are the most popular routes from Iowa to Buffalo?

While some choose either Des Moines - Buffalo or Cedar Rapids - Buffalo, Omaha Eppley Airfield - Buffalo is the most popular route from Iowa to Buffalo.

What are the most popular airlines that fly from Iowa to Buffalo?

When booking a flight from Iowa to Buffalo, you may want to consider flying on American Airlines, United Airlines or Delta as they are the most popular for this route.

What is the cheapest time of day to fly from IA to BUF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Iowa to Buffalo as you normally would.

What airport do you fly into for flights to Buffalo from Iowa?

Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Iowa. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

Can I find deals for flights from Iowa to Buffalo that include hotel bookings?

Yes. In addition to deals on Iowa to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Iowa to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Buffalo.

Can I find deals for business class flights from Iowa to Buffalo?

Yes. Cheapflights offers flight deals from Iowa to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$269+ Flights from Iowa to Buffalo

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Cheap flight deals from Iowa to Buffalo

Cheapest flights from Iowa to Buffalo
Explore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Mon 12/293:27 pmCID - BUF

1 stop6h 17mAmerican Airlines

Sat 1/36:00 amBUF - CID

2 stops8h 52mAmerican Airlines

Deal found 12/26

$359

Mon 12/296:30 amCID - BUF

2 stops6h 44mUnited Airlines

Sat 1/35:35 pmBUF - CID

1 stop4h 59mUnited Airlines

Deal found 12/25

$429

Tue 12/306:15 amDSM - BUF

1 stop4h 06mDelta

Fri 1/26:00 amBUF - DSM

1 stop5h 38mDelta

Deal found 12/27

$627

Tue 12/305:30 amDSM - BUF

2 stops13h 30mSouthwest

Fri 1/25:30 amBUF - DSM

2 stops6h 30mSouthwest

Deal found 12/27

$643

Tue 12/303:14 pmDSM - BUF

1 stop4h 40mUnited Airlines

Fri 1/26:30 amBUF - DSM

2 stops10h 55mUnited Airlines

Deal found 12/27

$682

Tue 12/301:34 pmDSM - BUF

2 stops8h 58mAmerican Airlines

Fri 1/212:32 pmBUF - DSM

1 stop6h 55mAmerican Airlines

Deal found 12/27

$763

Sun 12/289:35 amOMA - BUF

1 stop5h 54mAmerican Airlines

Sun 12/286:29 pmBUF - OMA

1 stop4h 41mAmerican Airlines

Deal found 12/26

$931

Fri 12/266:19 amOMA - BUF

1 stop4h 02mDelta

Mon 12/296:10 amBUF - OMA

1 stop4h 37mDelta

Deal found 12/25

$937

Sat 12/279:05 pmOMA - BUF

2 stops9h 50mSouthwest

Fri 1/26:55 amBUF - OMA

1 stop6h 50mSouthwest

Deal found 12/27

$942

Fri 12/262:12 pmOMA - BUF

2 stops7h 57mAmerican Airlines

Mon 12/295:20 pmBUF - OMA

1 stop6h 39mAmerican Airlines

Deal found 12/25

$1,099

Sun 12/283:14 pmOMA - BUF

1 stop4h 40mUnited Airlines

Sat 1/32:50 pmBUF - OMA

2 stops8h 08mUnited Airlines

Deal found 12/27

$1,202

Sun 12/285:45 amOMA - BUF

2 stops10h 09mUnited Airlines

Sun 12/287:48 pmBUF - OMA

2 stops15h 58mUnited Airlines

Deal found 12/26

$1,304

Best flights from Iowa to Buffalo
Discover carefully curated flight deals from Iowa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Sat 2/285:01 pmMLI - BUF

1 stop5h 25mDelta

Mon 3/94:47 pmBUF - MLI

1 stop6h 43mDelta

Deal found 12/26

$269

Fri 1/163:41 pmCID - BUF

1 stop6h 52mAmerican Airlines

Mon 1/196:53 pmBUF - CID

1 stop5h 12mAmerican Airlines

Deal found 12/27

$274

Sat 1/178:00 amCID - BUF

2 stops10h 25mUnited Airlines

Tue 1/2010:45 amBUF - CID

1 stop4h 35mUnited Airlines

Deal found 12/26

$274

Tue 1/276:10 amDSM - BUF

2 stops8h 00mSouthwest

Tue 2/312:20 pmBUF - DSM

2 stops9h 50mSouthwest

Deal found 12/27

$327

Wed 3/45:01 pmMLI - BUF

1 stop5h 25mDelta

Mon 3/94:47 pmBUF - MLI

1 stop6h 43mDelta

Deal found 12/26

$269

Sat 1/103:10 pmCID - BUF

1 stop4h 19mUnited Airlines

Wed 1/145:23 pmBUF - CID

1 stop5h 11mUnited Airlines

Deal found 12/26

$279

Mon 3/25:01 pmMLI - BUF

1 stop5h 26mDelta

Thu 3/124:47 pmBUF - MLI

1 stop6h 43mDelta

Deal found 12/26

$269

Tue 3/35:01 pmMLI - BUF

1 stop5h 25mDelta

Tue 3/104:47 pmBUF - MLI

1 stop6h 43mDelta

Deal found 12/26

$269

Thu 1/156:00 amDSM - BUF

1 stop5h 08mAmerican Airlines

Thu 1/226:53 pmBUF - DSM

1 stop5h 15mAmerican Airlines

Deal found 12/26

$341

Tue 1/2711:30 amDSM - BUF

1 stop4h 14mUnited Airlines

Tue 2/310:45 amBUF - DSM

1 stop4h 48mUnited Airlines

Deal found 12/27

$317

Wed 3/45:01 pmMLI - BUF

1 stop5h 25mDelta

Tue 3/104:47 pmBUF - MLI

1 stop6h 43mDelta

Deal found 12/26

$269

Thu 4/95:25 amDSM - BUF

1 stop3h 50mSouthwest

Wed 4/158:20 amBUF - DSM

1 stop4h 05mSouthwest

Deal found 12/27

$387

Wed 3/45:01 pmMLI - BUF

1 stop5h 25mDelta

Sun 3/84:47 pmBUF - MLI

1 stop6h 43mDelta

Deal found 12/26

$269

Tue 2/312:45 pmSUX - BUF

1 stop6h 44mUnited Airlines

Sat 2/79:55 amBUF - SUX

2 stops8h 33mUnited Airlines

Deal found 12/27

$334

Sat 3/75:16 pmOMA - BUF

1 stop5h 37mAmerican Airlines

Wed 3/116:19 amBUF - OMA

1 stop8h 50mAmerican Airlines

Deal found 12/27

$374

Sat 2/285:01 pmMLI - BUF

1 stop5h 25mDelta

Tue 3/104:47 pmBUF - MLI

1 stop6h 43mDelta

Deal found 12/26

$269

Sat 2/143:22 pmOMA - BUF

1 stop4h 29mUnited Airlines

Wed 2/188:25 amBUF - OMA

1 stop8h 52mUnited Airlines

Deal found 12/25

$339

Fri 1/165:01 pmDSM - BUF

1 stop16h 51mAmerican Airlines

Mon 1/195:12 amBUF - DSM

1 stop8h 34mAmerican Airlines

Deal found 12/27

$386

Mon 3/25:01 pmMLI - BUF

1 stop5h 26mDelta

Tue 3/104:47 pmBUF - MLI

1 stop6h 43mDelta

Deal found 12/26

$269

Wed 5/135:51 amOMA - BUF

1 stop3h 55mAmerican Airlines

Tue 5/196:08 amBUF - OMA

2 stops7h 29mAmerican Airlines

Deal found 12/26

$392

Sat 2/285:01 pmMLI - BUF

1 stop5h 25mDelta

Thu 3/124:47 pmBUF - MLI

1 stop6h 43mDelta

Deal found 12/26

$269

Sat 2/283:24 pmDSM - BUF

1 stop4h 27mUnited Airlines

Wed 3/47:00 amBUF - DSM

1 stop4h 53mUnited Airlines

Deal found 12/25

$387

Wed 3/412:23 pmCID - BUF

2 stops9h 34mDelta

Tue 3/104:47 pmBUF - CID

1 stop6h 32mDelta

Deal found 12/26

$274

Mon 3/212:23 pmCID - BUF

2 stops9h 16mDelta

Tue 3/104:47 pmBUF - CID

1 stop6h 32mDelta

Deal found 12/26

$274

Mon 3/212:23 pmCID - BUF

2 stops9h 16mDelta

Wed 3/114:47 pmBUF - CID

1 stop6h 32mDelta

Deal found 12/26

$274

Wed 3/412:23 pmCID - BUF

2 stops9h 34mDelta

Fri 3/134:47 pmBUF - CID

1 stop6h 32mDelta

Deal found 12/26

$274

Mon 3/25:01 pmMLI - BUF

1 stop5h 26mDelta

Sat 3/711:52 amBUF - MLI

2 stops11h 32mDelta

Deal found 12/26

$274

Tue 3/35:01 pmMLI - BUF

1 stop5h 25mDelta

Sat 3/711:52 amBUF - MLI

2 stops11h 32mDelta

Deal found 12/26

$274

Sun 1/1112:45 pmSUX - BUF

1 stop6h 44mUnited Airlines

Thu 1/158:30 amBUF - SUX

1 stop9h 58mUnited Airlines

Deal found 12/27

$707

Wed 3/412:23 pmCID - BUF

2 stops9h 34mDelta

Wed 3/117:00 amBUF - CID

2 stops16h 19mDelta

Deal found 12/26

$311

Last-minute flights from Iowa to Buffalo
Discover last-minute flight deals from Iowa to Buffalo. Data last updated December 28, 2025 and is based on user searches.

Mon 12/293:27 pmCID - BUF

2 stops7h 32mAmerican Airlines

Sat 1/36:00 amBUF - CID

2 stops8h 52mAmerican Airlines

Deal found 12/26

$364

Mon 12/296:30 amCID - BUF

2 stops6h 44mUnited Airlines

Sat 1/35:35 pmBUF - CID

1 stop4h 59mUnited Airlines

Deal found 12/25

$429

Sat 1/103:10 pmCID - BUF

1 stop4h 19mUnited Airlines

Wed 1/145:23 pmBUF - CID

1 stop5h 11mUnited Airlines

Deal found 12/26

$279

Sat 1/108:00 amCID - BUF

1 stop4h 24mUnited Airlines

Tue 1/1310:45 amBUF - CID

1 stop7h 07mUnited Airlines

Deal found 12/25

$349

Thu 1/156:00 amDSM - BUF

1 stop5h 08mAmerican Airlines

Thu 1/226:53 pmBUF - DSM

1 stop5h 15mAmerican Airlines

Deal found 12/26

$341

Fri 1/163:41 pmCID - BUF

1 stop6h 52mAmerican Airlines

Mon 1/196:53 pmBUF - CID

1 stop5h 12mAmerican Airlines

Deal found 12/27

$274

Fri 1/165:01 pmDSM - BUF

1 stop16h 51mAmerican Airlines

Mon 1/195:12 amBUF - DSM

1 stop8h 34mAmerican Airlines

Deal found 12/27

$386

Sat 1/173:10 pmCID - BUF

1 stop4h 19mUnited Airlines

Tue 1/2010:45 amBUF - CID

1 stop7h 07mUnited Airlines

Deal found 12/26

$269

Sat 1/243:45 pmMLI - BUF

1 stop3h 44mUnited Airlines

Tue 1/2710:45 amBUF - MLI

1 stop7h 09mUnited Airlines

Deal found 12/25

$339

Tue 1/2711:30 amDSM - BUF

1 stop4h 14mUnited Airlines

Tue 2/310:45 amBUF - DSM

1 stop4h 48mUnited Airlines

Deal found 12/27

$317

Tue 1/276:10 amDSM - BUF

2 stops8h 00mSouthwest

Tue 2/312:20 pmBUF - DSM

2 stops9h 50mSouthwest

Deal found 12/27

$327

Tue 1/276:30 amMLI - BUF

1 stop5h 54mUnited Airlines

Sat 1/318:30 amBUF - MLI

1 stop14h 06mUnited Airlines

Deal found 12/26

$434

One-way flights from Iowa to Buffalo
Search for one-way flight options from Iowa to Buffalo. Find affordable one-way fares based on user searches. Data last updated December 28, 2025.

Sat 1/36:10 amOMA - BUF

1 stop6h 14mUnited Airlines

Deal found 12/27

$349

Sat 1/36:48 pmOMA - BUF

3 stops45h 12mMultiple Airlines

Deal found 12/27

$721

Find flight deals from Iowa to Buffalo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$269 (United Airlines)
Popular in	February
Cheapest in	October
Average price	$555

Provider with most accurate pricing for Des Moines-Buffalo flight deals.

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Provider most trusted by Cheapflights users for Des Moines-Buffalo flights.

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From Iowa to Buffalo

Search Deals

Highest demand for flights based on searches. 23% potential increase in price ($125 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Sat 2/28

5:01 pm-11:26 pm

1 stop5h 25m

Buffalo

Mon 3/9

4:47 pm-10:30 pm

1 stop6h 43m

$269

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Wed 3/4

5:01 pm-11:26 pm

1 stop5h 25m

Buffalo

Mon 3/9

4:47 pm-10:30 pm

1 stop6h 43m

$269

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Mon 3/2

5:01 pm-11:27 pm

1 stop5h 26m

Buffalo

Thu 3/12

4:47 pm-10:30 pm

1 stop6h 43m

$269

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Tue 3/3

5:01 pm-11:26 pm

1 stop5h 25m

Buffalo

Tue 3/10

4:47 pm-10:30 pm

1 stop6h 43m

$269

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Wed 3/4

5:01 pm-11:26 pm

1 stop5h 25m

Buffalo

Tue 3/10

4:47 pm-10:30 pm

1 stop6h 43m

$269

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Wed 3/4

5:01 pm-11:26 pm

1 stop5h 25m

Buffalo

Sun 3/8

4:47 pm-10:30 pm

1 stop6h 43m

$269

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Sat 2/28

5:01 pm-11:26 pm

1 stop5h 25m

Buffalo

Tue 3/10

4:47 pm-10:30 pm

1 stop6h 43m

$269

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Mon 3/2

5:01 pm-11:27 pm

1 stop5h 26m

Buffalo

Tue 3/10

4:47 pm-10:30 pm

1 stop6h 43m

$269

MolineBuffalo

MLI - BUF

MLIBUF

Moline Quad-City

Sat 2/28

5:01 pm-11:26 pm

1 stop5h 25m

Buffalo

Thu 3/12

4:47 pm-10:30 pm

1 stop6h 43m

$269

Cedar RapidsBuffalo

CID - BUF

CIDBUF

Cedar Rapids

Fri 1/16

3:41 pm-11:33 pm

1 stop6h 52m

Buffalo

Mon 1/19

6:53 pm-11:05 pm

1 stop5h 12m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 32 results

Best time to book a flight from Iowa to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Iowa with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Buffalo

What is the cheapest month to book a flight from Iowa to Buffalo?

Currently, June is the cheapest month in which you can book a flight from Iowa to Buffalo (average of $100). Flying from Iowa to Buffalo in December is currently the most expensive (average of $294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

What airport do you fly into for flights to Buffalo from Iowa?
Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Iowa. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.
How long is the flight from Iowa to Buffalo?
Airlines like Delta, American Airlines, and United Airlines fly from Iowa to Buffalo in about 5h 25m. The time it takes to get you to your destination can typically vary by up to 5h. There are 611 mi between Iowa and Buffalo. This flight may include one or multiple stops.
What are the cheapest airlines to fly from Iowa to Buffalo one-way?
For one-way options, check prices for Delta. According to our data, you can fly for as low as $135. Users have also found prices from $148 and $151 on United Airlines and American Airlines, respectively.
What are the most popular routes from Iowa to Buffalo?
While some choose either Des Moines - Buffalo or Cedar Rapids - Buffalo, Omaha Eppley Airfield - Buffalo is the most popular route from Iowa to Buffalo.
Can I find deals for flights from Iowa to Buffalo that include hotel bookings?
Yes. In addition to deals on Iowa to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Iowa to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Buffalo.
Can I find deals for business class flights from Iowa to Buffalo?
Yes. Cheapflights offers flight deals from Iowa to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Iowa to Buffalo?
Currently, June is the cheapest month in which you can book a flight from Iowa to Buffalo (average of $100). Flying from Iowa to Buffalo in December is currently the most expensive (average of $294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Batavia

Williamsville

Orchard Park

Eden

Amherst

West Seneca

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Top 3 airlines flying from Iowa to Buffalo

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$148	Average$332	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$238	Average$309	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$278	Average$423	FlexibilityNo cancel fee	On-time69%

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$269+ Cheap flights from Iowa to Buffalo (BUF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Iowa to Buffalo

Cheapest flights from Iowa to BuffaloExplore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Explore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Find flight deals from Iowa to Buffalo

Keep the following information in mind while searching for Iowa to Buffalo flight deals. Data was last updated December 28, 2025.

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to Buffalo that are best for you.

Best time to book a flight from Iowa to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Iowa with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Buffalo

What is the cheapest month to book a flight from Iowa to Buffalo?

Related info for your journey

Find useful and relevant information for your journey from Iowa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Buffalo from Iowa?

How long is the flight from Iowa to Buffalo?

What are the cheapest airlines to fly from Iowa to Buffalo one-way?

What are the most popular routes from Iowa to Buffalo?

Can I find deals for flights from Iowa to Buffalo that include hotel bookings?

How can I find direct flights from Iowa to Buffalo?

Can I find deals for business class flights from Iowa to Buffalo?

What is the cheapest month to book a flight from Iowa to Buffalo?

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Top 3 airlines flying from Iowa to Buffalo

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Cheapest flights from Iowa to Buffalo
Explore the most affordable flight options available from Iowa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.