$184+ Cheap flights from Greenville to Buffalo (GSP - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BUF
Mar 5 — Mar 121
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Greenville to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Greenville to BuffaloExplore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:13 pm
GSP
- BUF
2 stops19h 40m
Multiple Airlines
Mon 3/911:44 am
BUF
- GSP
1 stop7h 54m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$236
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
GSP
- BUF
1 stop5h 19m
American Airlines
Mon 5/117:00 am
BUF
- GSP
1 stop5h 05m
American Airlines
Deal found 2/1![American Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:07 am
GSP
- BUF
1 stop5h 07m
American Airlines
Tue 3/107:23 am
BUF
- GSP
1 stop10h 50m
American Airlines
Deal found 2/3![American Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:18 pm
GSP
- BUF
1 stop22h 03m
Multiple Airlines
Mon 3/911:44 am
BUF
- GSP
1 stop7h 54m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$331
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:14 pm
GSP
- BUF
1 stop4h 41m
Delta
Sat 4/116:08 pm
BUF
- GSP
1 stop5h 46m
Delta
Deal found 2/2![Delta logo]()
$335
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:30 am
GSP
- BUF
2 stops7h 43m
United Airlines
Tue 3/101:52 pm
BUF
- GSP
1 stop6h 59m
United Airlines
Deal found 2/3![United Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/212:55 pm
GSP
- BUF
1 stop9h 55m
American Airlines
Mon 3/911:29 am
BUF
- GSP
1 stop10h 53m
American Airlines
Deal found 2/1![American Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:35 pm
GSP
- BUF
2 stops10h 10m
Southwest
Mon 5/115:45 am
BUF
- GSP
1 stop7h 30m
Southwest
Deal found 2/1![Southwest logo]()
$346
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:37 pm
GSP
- BUF
1 stop3h 54m
American Airlines
Mon 3/2311:29 am
BUF
- GSP
1 stop10h 53m
American Airlines
Deal found 1/31![American Airlines logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:18 pm
GSP
- BUF
1 stop22h 03m
Multiple Airlines
Fri 2/2010:42 am
BUF
- GSP
1 stop8h 56m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:13 am
GSP
- BUF
1 stop4h 45m
American Airlines
Mon 3/911:29 am
BUF
- GSP
1 stop10h 53m
American Airlines
Deal found 2/1![American Airlines logo]()
$366
Best flights from Greenville to BuffaloDiscover carefully curated flight deals from Greenville to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Greenville to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
GSP
- BUF
1 stop5h 19m
American Airlines
Mon 5/117:00 am
BUF
- GSP
1 stop5h 05m
American Airlines
Deal found 2/1![American Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:14 pm
GSP
- BUF
1 stop4h 41m
Delta
Sat 4/116:08 pm
BUF
- GSP
1 stop5h 46m
Delta
Deal found 2/2![Delta logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:18 pm
GSP
- BUF
1 stop22h 03m
Multiple Airlines
Fri 2/2010:42 am
BUF
- GSP
1 stop8h 56m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/912:25 pm
GSP
- BUF
2 stops8h 50m
Southwest
Mon 3/235:55 pm
BUF
- GSP
1 stop3h 55m
Southwest
Deal found 1/31![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:42 pm
GSP
- BUF
1 stop4h 10m
United Airlines
Sat 7/257:03 pm
BUF
- GSP
1 stop4h 41m
United Airlines
Deal found 1/31![United Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:39 pm
GSP
- BUF
1 stop4h 12m
American Airlines
Mon 7/275:54 am
BUF
- GSP
1 stop11h 36m
American Airlines
Deal found 2/1![American Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:10 am
GSP
- BUF
2 stops9h 50m
Southwest
Mon 5/1112:40 pm
BUF
- GSP
2 stops9h 35m
Southwest
Deal found 2/1![Southwest logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:33 pm
GSP
- BUF
2 stops17h 44m
Multiple Airlines
Fri 4/1011:54 am
BUF
- GSP
1 stop7h 44m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$391
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:30 am
GSP
- BUF
1 stop6h 47m
United Airlines
Wed 3/256:00 am
BUF
- GSP
2 stops10h 51m
United Airlines
Deal found 2/1![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:35 pm
GSP
- BUF
1 stop3h 55m
Southwest
Mon 3/912:05 pm
BUF
- GSP
2 stops10h 40m
Southwest
Deal found 2/1![Southwest logo]()
$382
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:00 am
GSP
- BUF
1 stop4h 58m
American Airlines
Wed 3/257:23 am
BUF
- GSP
1 stop10h 50m
American Airlines
Deal found 2/1![American Airlines logo]()
$383
Last-minute flights from Greenville to BuffaloDiscover last-minute flight deals from Greenville to Buffalo. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Buffalo. Data last updated February 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:18 pm
GSP
- BUF
1 stop22h 03m
Multiple Airlines
Fri 2/2010:42 am
BUF
- GSP
1 stop8h 56m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:13 pm
GSP
- BUF
2 stops19h 40m
Multiple Airlines
Mon 3/911:44 am
BUF
- GSP
1 stop7h 54m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$236
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:13 am
GSP
- BUF
1 stop4h 45m
American Airlines
Mon 3/911:29 am
BUF
- GSP
1 stop10h 53m
American Airlines
Deal found 2/1![American Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:18 pm
GSP
- BUF
1 stop22h 03m
Multiple Airlines
Mon 3/911:44 am
BUF
- GSP
1 stop7h 54m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$331
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/212:55 pm
GSP
- BUF
1 stop9h 55m
American Airlines
Mon 3/911:29 am
BUF
- GSP
1 stop10h 53m
American Airlines
Deal found 2/1![American Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:35 pm
GSP
- BUF
1 stop3h 55m
Southwest
Mon 3/912:05 pm
BUF
- GSP
2 stops10h 40m
Southwest
Deal found 2/1![Southwest logo]()
$382
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:07 am
GSP
- BUF
1 stop5h 07m
American Airlines
Tue 3/107:23 am
BUF
- GSP
1 stop10h 50m
American Airlines
Deal found 2/3![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:30 am
GSP
- BUF
2 stops7h 43m
United Airlines
Tue 3/101:52 pm
BUF
- GSP
1 stop6h 59m
United Airlines
Deal found 2/3![United Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:37 pm
GSP
- BUF
1 stop3h 54m
American Airlines
Mon 3/2311:29 am
BUF
- GSP
1 stop10h 53m
American Airlines
Deal found 1/31![American Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/912:25 pm
GSP
- BUF
2 stops8h 50m
Southwest
Mon 3/235:55 pm
BUF
- GSP
1 stop3h 55m
Southwest
Deal found 1/31![Southwest logo]()
$372
One-way flights from Greenville to BuffaloSearch for one-way flight options from Greenville to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Greenville to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:40 am
GSP
- BUF
1 stop5h 21m
Delta
Deal found 2/1![Delta logo]()
$184
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:30 am
GSP
- BUF
2 stops7h 44m
United Airlines
Deal found 2/1![United Airlines logo]()
$224
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2312:55 pm
GSP
- BUF
2 stops11h 15m
Southwest
Deal found 2/2![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2412:55 pm
GSP
- BUF
2 stops11h 15m
Southwest
Deal found 2/2![Southwest logo]()
$291
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3012:33 pm
GSP
- BUF
2 stops11h 17m
United Airlines
Deal found 2/1![United Airlines logo]()
$384
Find flight deals from Greenville to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $236 (Kiwi.com) |
One-way from | $184 (Delta) |
Popular in | December |
Cheapest in | September |
Average price | $364 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.
Fly from
Greenville
Fly to
Buffalo
Route
Depart
Return
Price
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Thu 5/7
6:00 am-11:19 am
1 stop5h 19m
Buffalo
Mon 5/11
7:00 am-12:05 pm
1 stop5h 05m
$303
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Mon 4/6
6:14 pm-10:55 pm
1 stop4h 41m
Buffalo
Sat 4/11
6:08 pm-11:54 pm
1 stop5h 46m
$335
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Thu 7/23
7:39 pm-11:51 pm
1 stop4h 12m
Buffalo
Mon 7/27
5:54 am-5:30 pm
1 stop11h 36m
$356
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Mon 2/16
8:18 pm-6:21 pm
1 stop22h 03m
Buffalo
Fri 2/20
10:42 am-7:38 pm
1 stop8h 56m
$365
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Mon 3/9
12:25 pm-9:15 pm
2 stops8h 50m
Buffalo
Mon 3/23
5:55 pm-9:50 pm
1 stop3h 55m
$372
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Thu 5/7
8:10 am-6:00 pm
2 stops9h 50m
Buffalo
Mon 5/11
12:40 pm-10:15 pm
2 stops9h 35m
$377
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Mon 3/2
6:35 pm-10:30 pm
1 stop3h 55m
Buffalo
Mon 3/9
12:05 pm-10:45 pm
2 stops10h 40m
$382
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Sat 3/21
6:00 am-10:58 am
1 stop4h 58m
Buffalo
Wed 3/25
7:23 am-6:13 pm
1 stop10h 50m
$383
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Sat 7/18
7:42 pm-11:52 pm
1 stop4h 10m
Buffalo
Sat 7/25
7:03 pm-11:44 pm
1 stop4h 41m
$387
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Mon 4/6
6:33 pm-12:17 pm
2 stops17h 44m
Buffalo
Fri 4/10
11:54 am-7:38 pm
1 stop7h 44m
$391
Showing 1-10 of 20 results
Compare providers for flights from Greenville to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Buffalo in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Greenville with our price prediction graph.
GSP-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to Buffalo
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated February 3, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Greenville to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Greenville to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Buffalo flight routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Greenville
Popular flights
Alternative routes for Greenville to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 3, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Greenville to Buffalo by cabin class
Find flights from Greenville to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and Buffalo flights
Browse other Greenville and Buffalo flight options. Last updated on February 3, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on February 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Greenville to Buffalo
Discover the top 3 airlines that operate flights from Greenville to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$311 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$218 | Average$346 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$277 | Average$336 | FlexibilityNo cancel fee | On-time63% |