HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Buffalo

$119+ Cheap flights from Greenville to Buffalo (GSP - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BUF
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greenville to Buffalo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Greenville to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$265
(Kiwi.com)

One-way from

$119
(Delta)

Popular in

October

Cheapest in

September

Average price

$476
Provider with most accurate pricing for Greenville-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Buffalo flights.
Search Deals
From Greenville to Buffalo
Search Deals
One-way flight from Greenville to Buffalo
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Greenville to Buffalo

Cheapest flights from Greenville to Buffalo
Explore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:03 pmGSP - BUF
1 stop22h 14mMultiple Airlines
Thu 11/132:42 pmBUF - GSP
2 stops28h 41mMultiple Airlines
Deal found 10/15$265
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:16 pmGSP - BUF
1 stop6h 34mDelta
Tue 11/186:10 amBUF - GSP
1 stop4h 17mDelta
Deal found 10/14$297
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:59 pmGSP - BUF
1 stop4h 58mDelta
Tue 11/42:35 pmBUF - GSP
1 stop7h 31mDelta
Deal found 10/16$314
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:13 pmGSP - BUF
1 stop5h 55mAmerican Airlines
Sat 11/223:27 pmBUF - GSP
2 stops6h 15mAmerican Airlines
Deal found 10/16$317
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:00 pmGSP - BUF
1 stop3h 40mSouthwest
Thu 11/135:45 amBUF - GSP
1 stop4h 00mSouthwest
Deal found 10/15$322
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1912:06 pmGSP - BUF
1 stop5h 42mAmerican Airlines
Fri 1/26:00 amBUF - GSP
1 stop4h 47mAmerican Airlines
Deal found 10/14$332
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/68:00 amGSP - BUF
1 stop4h 00mSouthwest
Sun 11/95:45 amBUF - GSP
1 stop4h 00mSouthwest
Deal found 10/15$342
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:01 amGSP - BUF
1 stop6h 09mAmerican Airlines
Mon 12/85:03 amBUF - GSP
1 stop5h 04mAmerican Airlines
Deal found 10/16$353
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/25:30 amGSP - BUF
1 stop5h 31mDelta
Tue 11/47:30 pmBUF - GSP
1 stop4h 25mDelta
Deal found 10/15$362
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1910:35 amGSP - BUF
2 stops11h 25mSouthwest
Fri 1/26:05 pmBUF - GSP
1 stop3h 50mSouthwest
Deal found 10/14$363
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:25 pmGSP - BUF
2 stops10h 33mUnited Airlines
Tue 11/46:00 amBUF - GSP
1 stop5h 31mUnited Airlines
Deal found 10/16$390

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.

Fly from

Greenville

Fly to

Buffalo

Route

Depart

Return

Price

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 11/7

8:03 pm-6:17 pm

1 stop22h 14m

Buffalo

Thu 11/13

2:42 pm-7:23 pm

2 stops28h 41m

$265

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 2/28

6:45 am-1:02 pm

1 stop6h 17m

Buffalo

Tue 3/3

6:50 pm-11:36 pm

1 stop4h 46m

$297

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 11/15

5:16 pm-11:50 pm

1 stop6h 34m

Buffalo

Tue 11/18

6:10 am-10:27 am

1 stop4h 17m

$297

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Mon 1/19

6:35 pm-10:30 pm

1 stop3h 55m

Buffalo

Thu 1/22

6:20 am-5:40 pm

2 stops11h 20m

$302

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 10/31

5:59 pm-10:57 pm

1 stop4h 58m

Buffalo

Tue 11/4

2:35 pm-10:06 pm

1 stop7h 31m

$314

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 11/7

8:00 pm-11:40 pm

1 stop3h 40m

Buffalo

Thu 11/13

5:45 am-9:45 am

1 stop4h 00m

$322

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 11/6

8:00 am-12:00 pm

1 stop4h 00m

Buffalo

Sun 11/9

5:45 am-9:45 am

1 stop4h 00m

$342

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 12/5

5:25 pm-11:24 pm

1 stop5h 59m

Buffalo

Mon 12/8

5:03 am-10:07 am

1 stop5h 04m

$353

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sun 11/2

5:30 am-11:01 am

1 stop5h 31m

Buffalo

Tue 11/4

7:30 pm-11:55 pm

1 stop4h 25m

$362

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 2/19

5:45 am-11:16 am

1 stop5h 31m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/16

Showing 1-10 of 19 results
1
2

Compare providers for flights from Greenville to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Buffalo in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Buffalo

What is the cheapest month to book a flight from Greenville to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $68). Flying from Greenville to Buffalo in December is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to BUF?

Find hourly flight availability from Greenville to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 4% on flights from Greenville to Buffalo by exploring options for tickets in the afternoon.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated October 16, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Greenville to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,984 reviews
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,043 reviews
Southwest
8.0
Very good
4,241 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Greenville to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Buffalo?

    For as low as $302, Delta can have you in Buffalo from Greenville in 3h 55m. The distance between Greenville and Buffalo is about 586 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Greenville to Buffalo round-trip?

    Cheapflights users have booked flights from Greenville to Buffalo round-trip from $216. Other airlines that can offer you cheap pricing are American Airlines, from $218, and Southwest, from $286. Users have found that Delta is 39% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Greenville to Buffalo one-way?

    $119 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $154 and $159, respectively.

  • Can I find deals for flights from Greenville to Buffalo that include hotel bookings?

    Yes. In addition to deals on Greenville to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Buffalo.

  • Can I find deals for business class flights from Greenville to Buffalo?

    Yes. Cheapflights offers flight deals from Greenville to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $68). Flying from Greenville to Buffalo in December is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Greenville to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Charlotte to LaGuardia flights
Charlotte to Newark flights
Charleston to John F Kennedy Intl flights
Charleston to Newark flights
Greenville to Newark flights
Savannah to John F Kennedy Intl flights
Greenville to John F Kennedy Intl flights
Columbia to LaGuardia flights
Greenville to LaGuardia flights
Savannah to Newark flights
Charleston to LaGuardia flights
Savannah to LaGuardia flights
Columbia to John F Kennedy Intl flights
Myrtle Beach to Newark flights
Myrtle Beach to John F Kennedy Intl flights
Myrtle Beach to LaGuardia flights
Charlotte to Buffalo flights
Columbia to Newark flights
Charlotte to Islip flights
Charleston to White Plains flights
Myrtle Beach to White Plains flights
Charlotte to Syracuse flights
Charlotte to Albany flights
Myrtle Beach to Stewart flights
Charleston to Stewart flights
Charlotte to Rochester flights
Charleston to Islip flights
Charlotte to White Plains flights
Charlotte to Stewart flights
Augusta to John F Kennedy Intl flights
Savannah to White Plains flights
Augusta to Newark flights
Augusta to LaGuardia flights
Charleston to Buffalo flights
Greenville to Syracuse flights
Myrtle Beach to Islip flights
Greenville to White Plains flights
Savannah to Albany flights
Columbia to Buffalo flights
Myrtle Beach to Syracuse flights
Greenville to Stewart flights
Columbia to Rochester flights
Charlotte to Ithaca flights
Greenville to Rochester flights
Savannah to Rochester flights
Charleston to Rochester flights
Columbia to Syracuse flights
Greenville to Albany flights

Top 3 airlines flying from Greenville to Buffalo

Discover the top 3 airlines that operate flights from Greenville to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$306FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$348FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$286Average$376FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.