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$154+ Cheap flights from Greenville to Buffalo (GSP - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BUF
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Greenville to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 20, 2025.

Round-trip from

$257
(Delta)

One-way from

$154
(American Airlines)

Popular in

December

Cheapest in

March

Average price

$386
From Greenville to Buffalo
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One-way flight from Greenville to Buffalo
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Highest demand for flights based on searches. 11% potential increase in price ($47 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Greenville to Buffalo

Cheapest flights from Greenville to Buffalo
Explore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/169:35 amGSP - BUF
1 stop7h 17mUnited Airlines
Tue 9/235:54 pmBUF - GSP
1 stop4h 52mUnited Airlines
Deal found 8/19$257
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:41 pmGSP - BUF
1 stop3h 58mDelta
Tue 10/216:03 amBUF - GSP
1 stop5h 05mDelta
Deal found 8/19$266
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/169:35 amGSP - BUF
2 stops9h 26mUnited Airlines
Mon 9/225:54 pmBUF - GSP
1 stop4h 52mUnited Airlines
Deal found 8/18$271
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/138:20 amGSP - BUF
1 stop4h 05mSouthwest
Sat 9/206:10 amBUF - GSP
1 stop3h 45mSouthwest
Deal found 8/19$275
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/161:50 pmGSP - BUF
1 stop10h 00mSouthwest
Tue 10/218:45 amBUF - GSP
2 stops11h 10mSouthwest
Deal found 8/19$277
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/139:17 amGSP - BUF
2 stops9h 44mUnited Airlines
Sat 9/205:54 pmBUF - GSP
1 stop4h 52mUnited Airlines
Deal found 8/19$280
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/25:35 amGSP - BUF
1 stop4h 26mDelta
Tue 11/45:45 pmBUF - GSP
1 stop4h 21mDelta
Deal found 8/19$282
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/25:00 amGSP - BUF
1 stop5h 08mAmerican Airlines
Tue 11/45:22 amBUF - GSP
2 stops6h 04mAmerican Airlines
Deal found 8/19$287
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:13 pmGSP - BUF
1 stop5h 24mDelta
Tue 10/76:00 amBUF - GSP
1 stop6h 47mDelta
Deal found 8/18$302
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:13 pmGSP - BUF
1 stop5h 24mDelta
Mon 10/66:20 amBUF - GSP
1 stop4h 28mDelta
Deal found 8/18$311
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/197:00 amGSP - BUF
1 stop6h 03mAmerican Airlines
Sun 9/216:07 pmBUF - GSP
1 stop4h 38mAmerican Airlines
Deal found 8/20$312

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.

Fly from

Greenville

Fly to

Buffalo

Route

Depart

Return

Price

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Tue 9/16

6:13 pm-11:37 pm

1 stop5h 24m

Buffalo

Tue 9/23

12:48 pm-6:14 pm

1 stop5h 26m

$257

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Tue 9/16

9:35 am-4:52 pm

1 stop7h 17m

Buffalo

Tue 9/23

5:54 pm-10:46 pm

1 stop4h 52m

$257

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Wed 9/24

9:30 am-3:10 pm

1 stop5h 40m

Buffalo

Sat 9/27

12:15 pm-4:30 pm

1 stop4h 15m

$266

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 10/16

5:30 am-11:01 am

1 stop5h 31m

Buffalo

Tue 10/21

10:08 am-2:30 pm

1 stop4h 22m

$266

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Tue 9/16

2:51 pm-7:01 pm

1 stop4h 10m

Buffalo

Mon 9/22

6:00 am-9:49 am

1 stop3h 49m

$266

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 10/4

5:21 pm-11:37 pm

1 stop6h 16m

Buffalo

Tue 10/7

6:03 am-11:08 am

1 stop5h 05m

$266

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Mon 9/15

7:44 pm-11:55 pm

1 stop4h 11m

Buffalo

Thu 9/18

5:38 am-10:55 am

1 stop5h 17m

$275

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 9/13

8:20 am-12:25 pm

1 stop4h 05m

Buffalo

Sat 9/20

6:10 am-9:55 am

1 stop3h 45m

$275

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 9/20

5:21 pm-11:37 pm

1 stop6h 16m

Buffalo

Sat 10/4

5:10 pm-9:07 pm

1 stop3h 57m

$275

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 10/3

7:39 am-2:05 pm

1 stop6h 26m

$154

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Showing 1-10 of 15 results
1
2

Best time to book a flight from Greenville to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Buffalo

What is the cheapest month to book a flight from Greenville to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $256). Flying from Greenville to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to BUF?

Find hourly flight availability from Greenville to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 5% on flights from Greenville to Buffalo by exploring options for tickets in the afternoon.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated August 20, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Greenville to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,982 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Buffalo?

    For as low as $257, Delta can have you in Buffalo from Greenville in 5h 24m. The distance between Greenville and Buffalo is about 586 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Greenville to Buffalo round-trip?

    Cheapflights users have booked flights from Greenville to Buffalo round-trip from $216. Other airlines that can offer you cheap pricing are Southwest, from $233, and American Airlines, from $236. Users have found that Delta is 37% cheaper than the other options available to this destination.

  • Can I find deals for flights from Greenville to Buffalo that include hotel bookings?

    Yes. In addition to deals on Greenville to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Buffalo.

  • Can I find deals for business class flights from Greenville to Buffalo?

    Yes. Cheapflights offers flight deals from Greenville to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $256). Flying from Greenville to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Top 3 airlines flying from Greenville to Buffalo

Discover the top 3 airlines that operate flights from Greenville to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$306FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$233Average$336FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$236Average$347FlexibilityNo cancel feeOn-time71%

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