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$100+ Cheap flights from Greenville to Buffalo (GSP - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BUF
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from Greenville to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$185
(Kiwi.com)

One-way from

$100
(Kiwi.com)

Popular in

October

Cheapest in

September

Average price

$364
Provider with most accurate pricing for Greenville-Buffalo flight deals.
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Provider most trusted by Cheapflights users for Greenville-Buffalo flights.
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From Greenville to Buffalo
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One-way flight from Greenville to Buffalo
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($4 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Greenville to Buffalo

Cheapest flights from Greenville to Buffalo
Explore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:00 pmGSP - BUF
1 stop19h 51mMultiple Airlines
Mon 12/153:18 pmBUF - GSP
1 stop25h 30mMultiple Airlines
Deal found 11/4$185
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/243:09 pmGSP - BUF
1 stop21h 55mMultiple Airlines
Mon 12/111:57 amBUF - GSP
1 stop9h 23mMultiple Airlines
Deal found 11/5$295
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:36 pmGSP - BUF
1 stop4h 23mDelta
Sat 12/612:10 pmBUF - GSP
1 stop4h 22mDelta
Deal found 11/4$297
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/212:06 pmGSP - BUF
1 stop5h 42mAmerican Airlines
Sat 12/611:39 amBUF - GSP
2 stops5h 59mAmerican Airlines
Deal found 11/4$302
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:55 amGSP - BUF
1 stop4h 07mAmerican Airlines
Wed 12/35:24 pmBUF - GSP
2 stops5h 40mAmerican Airlines
Deal found 11/4$303
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:35 amGSP - BUF
1 stop5h 29mDelta
Thu 12/46:00 amBUF - GSP
1 stop4h 55mDelta
Deal found 11/6$312
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:01 amGSP - BUF
2 stops5h 58mAmerican Airlines
Thu 12/45:05 amBUF - GSP
1 stop5h 29mAmerican Airlines
Deal found 11/6$317
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:25 amGSP - BUF
1 stop5h 09mDelta
Wed 12/172:57 pmBUF - GSP
1 stop7h 07mDelta
Deal found 11/4$332
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1110:35 amGSP - BUF
2 stops10h 05mSouthwest
Mon 12/157:40 amBUF - GSP
2 stops8h 25mSouthwest
Deal found 11/4$337

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.

Fly from

Greenville

Fly to

Buffalo

Route

Depart

Return

Price

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 12/11

4:00 pm-10:45 am

2 stops18h 45m

Buffalo

Mon 12/15

3:18 pm-4:48 pm

1 stop25h 30m

$222

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Mon 11/24

3:09 pm-1:04 pm

1 stop21h 55m

Buffalo

Mon 12/1

11:57 am-9:20 pm

1 stop9h 23m

$295

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 1/17

7:20 am-11:42 am

1 stop4h 22m

Buffalo

Sun 1/18

5:35 pm-10:44 pm

1 stop5h 09m

$297

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 11/27

3:02 pm-9:15 pm

1 stop6h 13m

Buffalo

Wed 12/3

6:00 am-10:55 am

1 stop4h 55m

$297

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Tue 12/2

7:36 pm-11:59 pm

1 stop4h 23m

Buffalo

Sat 12/6

12:10 pm-4:32 pm

1 stop4h 22m

$297

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 2/28

6:37 pm-10:59 pm

1 stop4h 22m

Buffalo

Tue 3/3

12:14 pm-6:39 pm

1 stop6h 25m

$297

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 1/17

7:20 am-11:42 am

1 stop4h 22m

Buffalo

Tue 1/20

5:45 pm-10:44 pm

1 stop4h 59m

$297

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 1/15

6:50 am-11:16 am

1 stop4h 26m

Buffalo

Sun 1/18

5:35 pm-10:44 pm

1 stop5h 09m

$312

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 1/17

7:20 am-11:42 am

1 stop4h 22m

Buffalo

Mon 1/19

5:44 pm-10:26 pm

1 stop4h 42m

$312

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 1/15

7:20 am-11:27 am

1 stop4h 07m

Buffalo

Tue 1/20

10:40 am-5:12 pm

1 stop6h 32m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 18 results
1
2

Compare providers for flights from Greenville to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Buffalo in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Buffalo

What is the cheapest month to book a flight from Greenville to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $68). Flying from Greenville to Buffalo in December is currently the most expensive (average of $203). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to BUF?

Find hourly flight availability from Greenville to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 4% on flights from Greenville to Buffalo by exploring options for tickets in the afternoon.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated November 6, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Greenville to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,040 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Greenville to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Buffalo?

    For as low as $297, Delta can have you in Buffalo from Greenville in 4h 22m. The distance between Greenville and Buffalo is about 586 mi.

  • What are the cheapest airlines flying from Greenville to Buffalo round-trip?

    Cheapflights users have booked flights from Greenville to Buffalo round-trip from $216. Other airlines that can offer you cheap pricing are American Airlines, from $218, and Southwest, from $286. Users have found that Delta is 38% cheaper than the other options available to this destination.

  • Can I find deals for flights from Greenville to Buffalo that include hotel bookings?

    Yes. In addition to deals on Greenville to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Buffalo.

  • Can I find deals for business class flights from Greenville to Buffalo?

    Yes. Cheapflights offers flight deals from Greenville to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $68). Flying from Greenville to Buffalo in December is currently the most expensive (average of $203). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Top 3 airlines flying from Greenville to Buffalo

Discover the top 3 airlines that operate flights from Greenville to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$311FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$347FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$286Average$376FlexibilityNo cancel feeOn-time63%

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