$136+ Cheap flights from Greenville to Buffalo (GSP - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BUF
Aug 31 — Sep 71
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to Buffalo with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Greenville to BuffaloExplore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.
Explore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:19 pm
GSP
- BUF
1 stop4h 36m
American Airlines
Sat 9/56:00 am
BUF
- GSP
1 stop6h 30m
American Airlines
Deal found 7/27![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:30 am
GSP
- BUF
1 stop6h 46m
United Airlines
Wed 9/22:53 pm
BUF
- GSP
2 stops8h 10m
United Airlines
Deal found 7/29![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:30 pm
GSP
- BUF
1 stop7h 27m
Delta
Thu 9/176:05 am
BUF
- GSP
1 stop5h 03m
Delta
Deal found 7/31![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:15 am
GSP
- BUF
1 stop6h 05m
Southwest
Wed 9/28:05 am
BUF
- GSP
2 stops8h 40m
Southwest
Deal found 7/29![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:04 am
GSP
- BUF
1 stop4h 09m
Delta
Tue 9/156:20 am
BUF
- GSP
1 stop4h 04m
Delta
Deal found 7/31![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/277:00 am
GSP
- BUF
1 stop4h 14m
Delta
Tue 12/16:00 am
BUF
- GSP
1 stop4h 35m
Delta
Deal found 7/29![Delta logo]()
$338
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:40 am
GSP
- BUF
2 stops7h 55m
Southwest
Sat 10/177:15 am
BUF
- GSP
1 stop3h 30m
Southwest
Deal found 7/31![Southwest logo]()
$356
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:39 am
GSP
- BUF
1 stop5h 26m
American Airlines
Fri 1/111:59 am
BUF
- GSP
1 stop5h 55m
American Airlines
Deal found 7/28![American Airlines logo]()
$360
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:01 pm
GSP
- BUF
1 stop3h 59m
United Airlines
Wed 9/26:00 am
BUF
- GSP
1 stop4h 37m
United Airlines
Deal found 7/28![United Airlines logo]()
$389
Best flights from Greenville to BuffaloDiscover carefully curated flight deals from Greenville to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 1, 2026.
Discover carefully curated flight deals from Greenville to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 1, 2026.
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
GSP
- BUF
1 stop7h 25m
Delta
Thu 9/1712:02 pm
BUF
- GSP
1 stop6h 15m
Delta
Deal found 7/29![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:40 am
GSP
- BUF
2 stops7h 55m
Southwest
Sat 10/177:15 am
BUF
- GSP
1 stop3h 30m
Southwest
Deal found 7/31![Southwest logo]()
$356
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:01 pm
GSP
- BUF
1 stop3h 59m
United Airlines
Wed 9/26:00 am
BUF
- GSP
1 stop4h 37m
United Airlines
Deal found 7/28![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:17 am
GSP
- BUF
2 stops8h 43m
United Airlines
Sat 9/510:30 am
BUF
- GSP
1 stop6h 32m
United Airlines
Deal found 7/27![United Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:04 pm
GSP
- BUF
1 stop4h 55m
Delta
Sun 10/116:10 am
BUF
- GSP
1 stop4h 08m
Delta
Deal found 7/31![Delta logo]()
$397
Last-minute flights from Greenville to BuffaloDiscover last-minute flight deals from Greenville to Buffalo. Data last updated August 1, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Buffalo. Data last updated August 1, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:57 pm
GSP
- BUF
2 stops18h 36m
Multiple Airlines
Sun 8/169:33 pm
BUF
- GSP
1 stop18h 27m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$452
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:37 pm
GSP
- BUF
1 stop4h 25m
American Airlines
Mon 8/176:59 pm
BUF
- GSP
1 stop3h 51m
American Airlines
Deal found 7/27![American Airlines logo]()
$393
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:00 am
GSP
- BUF
1 stop6h 29m
American Airlines
Sun 8/235:45 pm
BUF
- GSP
1 stop4h 52m
American Airlines
Deal found 7/31![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:30 am
GSP
- BUF
1 stop6h 46m
United Airlines
Wed 9/22:53 pm
BUF
- GSP
2 stops8h 10m
United Airlines
Deal found 7/29![United Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:15 am
GSP
- BUF
1 stop6h 05m
Southwest
Wed 9/28:05 am
BUF
- GSP
2 stops8h 40m
Southwest
Deal found 7/29![Southwest logo]()
$327
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:19 pm
GSP
- BUF
1 stop4h 36m
American Airlines
Sat 9/56:00 am
BUF
- GSP
1 stop6h 30m
American Airlines
Deal found 7/30![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:01 pm
GSP
- BUF
1 stop3h 59m
United Airlines
Wed 9/26:00 am
BUF
- GSP
1 stop4h 37m
United Airlines
Deal found 7/28![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:30 am
GSP
- BUF
2 stops7h 48m
United Airlines
Sat 9/56:00 am
BUF
- GSP
2 stops11h 02m
United Airlines
Deal found 7/31![United Airlines logo]()
$414
One-way flights from Greenville to BuffaloSearch for one-way flight options from Greenville to Buffalo. Find affordable one-way fares based on user searches. Data last updated August 1, 2026.
Search for one-way flight options from Greenville to Buffalo. Find affordable one-way fares based on user searches. Data last updated August 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:07 am
GSP
- BUF
2 stops26h 48m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$136
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:20 pm
GSP
- BUF
1 stop6h 39m
Delta
Deal found 7/30![Delta logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:45 pm
GSP
- BUF
2 stops37h 44m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$165
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:49 pm
GSP
- BUF
1 stop7h 05m
American Airlines
Deal found 7/30![American Airlines logo]()
$168
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:00 am
GSP
- BUF
2 stops7h 18m
United Airlines
Deal found 7/31![United Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:18 am
GSP
- BUF
2 stops29h 35m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$178
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:10 am
GSP
- BUF
1 stop4h 04m
Delta
Deal found 7/28![Delta logo]()
$239
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:18 pm
GSP
- BUF
1 stop6h 49m
United Airlines
Deal found 7/28![United Airlines logo]()
$419
Find flight deals from Greenville to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (American Airlines) |
One-way from | $136 (Kiwi.com) |
Popular in | March |
Cheapest in | November |
Average price | $395 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Thu 9/10
6:00 am-1:25 pm
1 stop7h 25m
Buffalo
Thu 9/17
12:02 pm-6:17 pm
1 stop6h 15m
$309
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Sat 10/10
6:40 am-2:35 pm
2 stops7h 55m
Buffalo
Sat 10/17
7:15 am-10:45 am
1 stop3h 30m
$356
Quickest round-trip
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Sat 8/29
3:01 pm-7:00 pm
1 stop3h 59m
Buffalo
Wed 9/2
6:00 am-10:37 am
1 stop4h 37m
$389
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Sat 8/29
10:17 am-7:00 pm
2 stops8h 43m
Buffalo
Sat 9/5
10:30 am-5:02 pm
1 stop6h 32m
$394
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Fri 10/9
7:04 pm-11:59 pm
1 stop4h 55m
Buffalo
Sun 10/11
6:10 am-10:18 am
1 stop4h 08m
$397
Cheapest one-way
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Thu 9/17
10:07 am-12:55 pm
2 stops26h 48m
$136
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Sat 8/29
5:20 pm-11:59 pm
1 stop6h 39m
$155
Quickest one-way
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Sat 8/29
8:10 am-12:06 pm
1 stop3h 56m
$155
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Thu 9/17
4:49 pm-11:54 pm
1 stop7h 05m
$168
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Fri 8/14
8:13 pm-11:33 am
3 stops15h 20m
$192
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Greenville to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Buffalo in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Greenville with our price prediction graph.
GSP-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to Buffalo
What is the cheapest month to book a flight from Greenville to Buffalo?
Currently, November is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $258). Flying from Greenville to Buffalo in March is currently the most expensive (average of $686). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to Buffalo?
Airfare is typical for this route at the moment.
Greenville to Buffalo flights typically cost between $254 and $466 in August.The cheapest round-trip price found within the last 5 days was $309 on American Airlines (Aug 29-Sep 5).
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated August 1, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Greenville to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Greenville to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 1, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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Greenville and Buffalo flights
Browse other Greenville and Buffalo flight options. Last updated on August 1, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on August 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Greenville to Buffalo
Discover the top 3 airlines that operate flights from Greenville to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$375 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$380 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$287 | Average$463 | FlexibilityNo cancel fee | On-time63% |