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$136+ Cheap flights from Greenville to Buffalo (GSP - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BUF
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from Greenville to Buffalo

Cheapest flights from Greenville to Buffalo
Explore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:59 pm
GSP
-
BUF
1 stop4h 32m
Delta
Tue 4/213:53 pm
BUF
-
GSP
1 stop6h 53m
Delta
Deal found 3/19$271
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:59 pm
GSP
-
BUF
1 stop4h 32m
Delta
Sat 4/256:15 am
BUF
-
GSP
1 stop6h 30m
Delta
Deal found 3/19$281
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:35 pm
GSP
-
BUF
1 stop4h 07m
American Airlines
Wed 5/65:12 pm
BUF
-
GSP
1 stop5h 07m
American Airlines
Deal found 3/20$289
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:51 am
GSP
-
BUF
1 stop4h 10m
Delta
Sat 4/254:03 pm
BUF
-
GSP
1 stop6h 43m
Delta
Deal found 3/19$291
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:30 am
GSP
-
BUF
2 stops7h 47m
United Airlines
Tue 4/217:00 am
BUF
-
GSP
1 stop4h 54m
United Airlines
Deal found 3/17$306
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:42 pm
GSP
-
BUF
1 stop4h 08m
United Airlines
Tue 4/1410:35 am
BUF
-
GSP
2 stops10h 12m
United Airlines
Deal found 3/19$311
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:27 pm
GSP
-
BUF
1 stop5h 06m
United Airlines
Wed 5/66:04 am
BUF
-
GSP
1 stop3h 54m
United Airlines
Deal found 3/17$315
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
GSP
-
BUF
1 stop5h 14m
American Airlines
Sat 5/167:00 am
BUF
-
GSP
1 stop5h 14m
American Airlines
Deal found 3/20$320
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:35 am
GSP
-
BUF
1 stop5h 15m
Delta
Sun 4/197:40 pm
BUF
-
GSP
1 stop4h 16m
Delta
Deal found 3/20$329

Find flight deals from Greenville to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$271
(Delta)

One-way from

$136
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$334
Provider with most accurate pricing for Greenville-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Buffalo flights.
Search Deals
From Greenville to Buffalo
Search Deals
One-way flight from Greenville to Buffalo
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Thu 5/14

6:00 am-11:14 am

1 stop5h 14m

Buffalo

Sat 5/16

5:00 am-10:36 am

1 stop5h 36m

$291
Quickest round-trip

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Mon 5/4

6:27 pm-11:33 pm

1 stop5h 06m

Buffalo

Wed 5/6

6:04 am-9:58 am

1 stop3h 54m

$315

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Mon 6/1

1:50 pm-7:45 pm

1 stop5h 55m

Buffalo

Mon 6/8

12:40 pm-9:35 pm

2 stops8h 55m

$344

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Wed 4/29

7:42 pm-11:52 pm

1 stop4h 10m

Buffalo

Sat 5/2

6:10 am-2:10 pm

2 stops8h 00m

$366

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Tue 4/14

12:50 pm-10:15 pm

2 stops9h 25m

Buffalo

Tue 4/21

9:45 am-1:10 pm

1 stop3h 25m

$374

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 5/1

10:40 am-4:48 pm

1 stop6h 08m

Buffalo

Sun 5/3

6:10 am-9:58 am

1 stop3h 48m

$387

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 6/5

1:55 pm-7:15 pm

1 stop5h 20m

Buffalo

Sun 6/7

11:50 am-6:50 pm

1 stop7h 00m

$387

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Fri 5/1

12:35 pm-6:10 pm

1 stop5h 35m

Buffalo

Sun 5/3

2:55 pm-11:25 pm

2 stops8h 30m

$392

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Sat 7/25

8:15 am-1:55 pm

1 stop5h 40m

Buffalo

Mon 7/27

8:45 am-6:15 pm

2 stops9h 30m

$392
Cheapest one-way

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

Wed 4/15

6:30 am-11:58 am

1 stop5h 28m

$136

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Greenville to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Buffalo in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Buffalo

What is the cheapest month to book a flight from Greenville to Buffalo?

Currently, June is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $145). Flying from Greenville to Buffalo in February is currently the most expensive (average of $217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated March 22, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Greenville to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,324 reviews
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,314 reviews
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,489 reviews
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Buffalo?

    For as low as $315, American Airlines can have you in Buffalo from Greenville in 5h 06m. The distance between Greenville and Buffalo is about 586 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Greenville to Buffalo round-trip?

    Cheapflights users have booked flights from Greenville to Buffalo round-trip from $216. Other airlines that can offer you cheap pricing are American Airlines, from $236, and Southwest, from $277. Users have found that Delta is 40% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Greenville to Buffalo one-way?

    $87 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $153 and $178, respectively.

  • Can I find deals for flights from Greenville to Buffalo that include hotel bookings?

    Yes. In addition to deals on Greenville to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Buffalo.

  • Can I find deals for business class flights from Greenville to Buffalo?

    Yes. Cheapflights offers flight deals from Greenville to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Buffalo?

    Currently, June is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $145). Flying from Greenville to Buffalo in February is currently the most expensive (average of $217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

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Top 3 airlines flying from Greenville to Buffalo

Discover the top 3 airlines that operate flights from Greenville to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$316FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$346FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$277Average$336FlexibilityNo cancel feeOn-time63%

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