$136+ Cheap flights from Greenville to Buffalo (GSP - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BUF
Jun 6 — Jun 131
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Buffalo
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Cheapest flights from Greenville to BuffaloExplore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.
Explore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:24 am
GSP
- BUF
1 stop10h 48m
Multiple Airlines
Mon 6/292:50 pm
BUF
- GSP
2 stops24h 16m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:19 am
GSP
- BUF
1 stop10h 53m
Multiple Airlines
Sun 6/149:02 pm
BUF
- GSP
1 stop10h 37m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$268
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:07 pm
GSP
- BUF
1 stop4h 51m
Delta
Wed 8/194:13 pm
BUF
- GSP
1 stop4h 19m
Delta
Deal found 5/4![Delta logo]()
$271
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:55 pm
GSP
- BUF
1 stop4h 20m
Southwest
Sat 5/303:40 pm
BUF
- GSP
1 stop5h 00m
Southwest
Deal found 5/3![Southwest logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:57 pm
GSP
- BUF
2 stops18h 36m
Multiple Airlines
Thu 8/208:57 pm
BUF
- GSP
1 stop18h 46m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:07 am
GSP
- BUF
2 stops26h 48m
Multiple Airlines
Sun 8/238:57 pm
BUF
- GSP
1 stop18h 46m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:57 pm
GSP
- BUF
2 stops18h 36m
Multiple Airlines
Sun 8/238:57 pm
BUF
- GSP
1 stop18h 46m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$296
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:50 pm
GSP
- BUF
2 stops7h 35m
Southwest
Wed 6/1011:00 am
BUF
- GSP
2 stops8h 00m
Southwest
Deal found 5/4![Southwest logo]()
$301
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:00 am
GSP
- BUF
2 stops8h 40m
Southwest
Tue 6/239:00 am
BUF
- GSP
1 stop4h 10m
Southwest
Deal found 5/4![Southwest logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:43 pm
GSP
- BUF
2 stops22h 11m
Multiple Airlines
Sun 5/248:49 pm
BUF
- GSP
1 stop10h 44m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$321
Best flights from Greenville to BuffaloDiscover carefully curated flight deals from Greenville to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.
Discover carefully curated flight deals from Greenville to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:55 pm
GSP
- BUF
1 stop10h 15m
Southwest
Sun 6/146:00 pm
BUF
- GSP
1 stop3h 40m
Southwest
Deal found 5/2![Southwest logo]()
$344
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:40 pm
GSP
- BUF
1 stop4h 18m
United Airlines
Wed 6/106:00 am
BUF
- GSP
1 stop4h 37m
United Airlines
Deal found 5/6![United Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:10 am
GSP
- BUF
1 stop4h 12m
Delta
Fri 7/175:12 pm
BUF
- GSP
1 stop6h 42m
Delta
Deal found 5/3![Delta logo]()
$387
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:55 pm
GSP
- BUF
1 stop10h 15m
Southwest
Sun 6/73:25 pm
BUF
- GSP
2 stops7h 55m
Southwest
Deal found 5/5![Southwest logo]()
$350
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/131:55 pm
GSP
- BUF
1 stop5h 20m
Southwest
Fri 7/172:50 pm
BUF
- GSP
1 stop6h 45m
Southwest
Deal found 5/4![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/101:55 pm
GSP
- BUF
1 stop5h 20m
Southwest
Sun 7/126:00 pm
BUF
- GSP
1 stop3h 40m
Southwest
Deal found 5/2![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:25 am
GSP
- BUF
1 stop3h 45m
Southwest
Tue 7/214:25 pm
BUF
- GSP
1 stop3h 50m
Southwest
Deal found 5/3![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:15 am
GSP
- BUF
1 stop5h 45m
Southwest
Sun 7/123:00 pm
BUF
- GSP
1 stop6h 40m
Southwest
Deal found 5/2![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/181:55 pm
GSP
- BUF
1 stop10h 15m
Southwest
Sun 6/213:00 pm
BUF
- GSP
1 stop6h 40m
Southwest
Deal found 5/5![Southwest logo]()
$392
Last-minute flights from Greenville to BuffaloDiscover last-minute flight deals from Greenville to Buffalo. Data last updated May 7, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Buffalo. Data last updated May 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:43 pm
GSP
- BUF
2 stops22h 11m
Multiple Airlines
Sun 5/248:49 pm
BUF
- GSP
1 stop10h 44m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:23 am
GSP
- BUF
1 stop10h 36m
Multiple Airlines
Sun 5/248:49 pm
BUF
- GSP
1 stop10h 44m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:55 pm
GSP
- BUF
1 stop4h 20m
Southwest
Sat 5/303:40 pm
BUF
- GSP
1 stop5h 00m
Southwest
Deal found 5/3![Southwest logo]()
$281
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:55 am
GSP
- BUF
1 stop6h 35m
Delta
Wed 6/1010:20 am
BUF
- GSP
1 stop7h 07m
Delta
Deal found 5/4![Delta logo]()
$271
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:50 pm
GSP
- BUF
2 stops7h 35m
Southwest
Wed 6/1011:00 am
BUF
- GSP
2 stops8h 00m
Southwest
Deal found 5/4![Southwest logo]()
$301
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:40 pm
GSP
- BUF
1 stop4h 18m
United Airlines
Thu 6/116:00 am
BUF
- GSP
1 stop4h 37m
United Airlines
Deal found 5/4![United Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:19 am
GSP
- BUF
1 stop10h 53m
Multiple Airlines
Sun 6/149:02 pm
BUF
- GSP
1 stop10h 37m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$268
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:00 am
GSP
- BUF
2 stops8h 40m
Southwest
Tue 6/239:00 am
BUF
- GSP
1 stop4h 10m
Southwest
Deal found 5/4![Southwest logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:19 am
GSP
- BUF
1 stop10h 53m
Multiple Airlines
Sun 6/2811:35 am
BUF
- GSP
2 stops26h 56m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:24 am
GSP
- BUF
1 stop10h 48m
Multiple Airlines
Mon 6/292:50 pm
BUF
- GSP
2 stops24h 16m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$261
One-way flights from Greenville to BuffaloSearch for one-way flight options from Greenville to Buffalo. Find affordable one-way fares based on user searches. Data last updated May 7, 2026.
Search for one-way flight options from Greenville to Buffalo. Find affordable one-way fares based on user searches. Data last updated May 7, 2026.
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:55 pm
GSP
- BUF
1 stop5h 04m
Delta
Deal found 5/2![Delta logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:28 pm
GSP
- BUF
1 stop22h 44m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$151
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:45 am
GSP
- BUF
2 stops7h 50m
Southwest
Deal found 5/4![Southwest logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:28 pm
GSP
- BUF
2 stops41h 26m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$216
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:35 pm
GSP
- BUF
1 stop5h 24m
Delta
Deal found 5/4![Delta logo]()
$234
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:16 am
GSP
- BUF
2 stops6h 46m
American Airlines
Deal found 5/4![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/179:33 am
GSP
- BUF
1 stop9h 13m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$289
Find flight deals from Greenville to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $261 (Kiwi.com) |
One-way from | $136 (American Airlines) |
Popular in | March |
Cheapest in | September |
Average price | $376 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Thu 6/4
1:55 pm-12:10 am
1 stop10h 15m
Buffalo
Sun 6/14
6:00 pm-9:40 pm
1 stop3h 40m
$344
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Thu 6/4
1:55 pm-12:10 am
1 stop10h 15m
Buffalo
Sun 6/7
3:25 pm-11:20 pm
2 stops7h 55m
$350
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Tue 6/9
7:40 pm-11:58 pm
1 stop4h 18m
Buffalo
Wed 6/10
6:00 am-10:37 am
1 stop4h 37m
$367
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Fri 7/17
7:10 am-11:22 am
1 stop4h 12m
Buffalo
Fri 7/17
5:12 pm-11:54 pm
1 stop6h 42m
$387
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Mon 7/13
1:55 pm-7:15 pm
1 stop5h 20m
Buffalo
Fri 7/17
2:50 pm-9:35 pm
1 stop6h 45m
$387
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Fri 7/10
1:55 pm-7:15 pm
1 stop5h 20m
Buffalo
Sun 7/12
6:00 pm-9:40 pm
1 stop3h 40m
$387
Quickest round-trip
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Tue 7/14
8:25 am-12:10 pm
1 stop3h 45m
Buffalo
Tue 7/21
4:25 pm-8:15 pm
1 stop3h 50m
$387
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Sat 7/11
8:15 am-2:00 pm
1 stop5h 45m
Buffalo
Sun 7/12
3:00 pm-9:40 pm
1 stop6h 40m
$387
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Thu 6/18
1:55 pm-12:10 am
1 stop10h 15m
Buffalo
Sun 6/21
3:00 pm-9:40 pm
1 stop6h 40m
$392
Cheapest one-way
GreenvilleBuffalo
GSP - BUF
GSPBUF
Greenville
Tue 6/30
6:14 am-10:33 am
1 stop4h 19m
$136
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Greenville to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Buffalo in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Greenville with our price prediction graph.
GSP-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to Buffalo
What is the cheapest month to book a flight from Greenville to Buffalo?
Currently, September is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $265). Flying from Greenville to Buffalo in March is currently the most expensive (average of $686). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to Buffalo?
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated May 7, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Greenville to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
7.9
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
7.9
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
7.9
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Greenville to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
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Alternative routes for Greenville to Buffalo
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 7, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Greenville to Buffalo by cabin class
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Greenville and Buffalo flights
Browse other Greenville and Buffalo flight options. Last updated on May 7, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on May 7, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Greenville to Buffalo
Discover the top 3 airlines that operate flights from Greenville to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$346 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$346 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$287 | Average$401 | FlexibilityNo cancel fee | On-time63% |