HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Buffalo

$136+ Cheap flights from Greenville to Buffalo (GSP - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BUF
feb. 20 — feb. 271
vie. 2/20
vie. 2/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greenville to Buffalo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Greenville to Buffalo

Cheapest flights from Greenville to Buffalo
Explore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 21, 2026.

This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/166:45 pm
GSP
-
BUF
1 stop4h 12m
Delta
lun. 2/235:44 pm
BUF
-
GSP
1 stop4h 40m
Delta
Deal found 1/18$303
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/176:01 pm
GSP
-
BUF
1 stop4h 38m
Delta
dom. 2/226:45 pm
BUF
-
GSP
1 stop4h 58m
Delta
Deal found 1/20$319
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/177:37 pm
GSP
-
BUF
1 stop3h 54m
American Airlines
dom. 2/226:00 am
BUF
-
GSP
2 stops6h 00m
American Airlines
Deal found 1/20$324
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/25:40 am
GSP
-
BUF
1 stop5h 21m
Delta
mar. 4/74:53 pm
BUF
-
GSP
1 stop4h 59m
Delta
Deal found 1/19$335
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/1310:49 am
GSP
-
BUF
1 stop6h 03m
American Airlines
lun. 2/167:41 pm
BUF
-
GSP
1 stop4h 13m
American Airlines
Deal found 1/20$345
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/1412:05 pm
GSP
-
BUF
1 stop5h 45m
United Airlines
mié. 2/186:25 pm
BUF
-
GSP
1 stop5h 34m
United Airlines
Deal found 1/19$367
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/206:53 pm
GSP
-
BUF
1 stop3h 57m
American Airlines
dom. 3/14:25 pm
BUF
-
GSP
1 stop4h 21m
American Airlines
Deal found 1/20$376

Find flight deals from Greenville to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$271
(Delta)

One-way from

$136
(Delta)

Popular in

December

Cheapest in

September

Average price

$462
Provider with most accurate pricing for Greenville-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Buffalo flights.
Search Deals
From Greenville to Buffalo
Search Deals
One-way flight from Greenville to Buffalo
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($59 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.

Fly from

Greenville

Fly to

Buffalo

Route

Depart

Return

Price

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

lun. 2/16

6:45 pm-10:57 pm

1 stop4h 12m

Buffalo

lun. 2/23

5:44 pm-10:24 pm

1 stop4h 40m

$303

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

mar. 2/17

7:37 pm-11:31 pm

1 stop3h 54m

Buffalo

dom. 2/22

6:00 am-12:00 pm

2 stops6h 00m

$324

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

jue. 4/2

5:40 am-11:01 am

1 stop5h 21m

Buffalo

mar. 4/7

4:53 pm-9:52 pm

1 stop4h 59m

$335

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

vie. 2/13

10:49 am-4:52 pm

1 stop6h 03m

Buffalo

lun. 2/16

7:41 pm-11:54 pm

1 stop4h 13m

$345

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

sáb. 2/14

12:05 pm-5:50 pm

1 stop5h 45m

Buffalo

mié. 2/18

6:00 am-11:21 am

1 stop5h 21m

$367

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

jue. 4/2

1:55 pm-8:35 pm

1 stop6h 40m

Buffalo

mar. 4/7

8:20 am-4:20 pm

2 stops8h 00m

$392

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

mié. 3/25

6:21 pm-11:13 pm

1 stop4h 52m

$136

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

mié. 3/25

6:00 am-10:58 am

1 stop4h 58m

$152

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

mié. 3/25

12:07 pm-6:42 pm

2 stops6h 35m

$288

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Compare providers for flights from Greenville to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Buffalo in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Buffalo flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Buffalo

What is the cheapest month to book a flight from Greenville to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $101). Flying from Greenville to Buffalo in December is currently the most expensive (average of $215). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated enero 21, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Greenville to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,266 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,089 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,174 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Greenville to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Buffalo?

    For as low as $324, Delta can have you in Buffalo from Greenville in 3h 54m. The distance between Greenville and Buffalo is about 586 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Greenville to Buffalo round-trip?

    Cheapflights users have booked flights from Greenville to Buffalo round-trip from $216. Other airlines that can offer you cheap pricing are American Airlines, from $218, and Southwest, from $277. Users have found that Delta is 40% cheaper than the other options available to this destination.

  • Can I find deals for flights from Greenville to Buffalo that include hotel bookings?

    Yes. In addition to deals on Greenville to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Buffalo.

  • Can I find deals for business class flights from Greenville to Buffalo?

    Yes. Cheapflights offers flight deals from Greenville to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $101). Flying from Greenville to Buffalo in December is currently the most expensive (average of $215). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Greenville to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Charlotte to Newark flights
Charlotte to LaGuardia flights
Greenville to Newark flights
Columbia to LaGuardia flights
Savannah to John F Kennedy Intl flights
Columbia to John F Kennedy Intl flights
Charleston to Newark flights
Charleston to John F Kennedy Intl flights
Charleston to LaGuardia flights
Greenville to LaGuardia flights
Savannah to Newark flights
Columbia to Newark flights
Savannah to LaGuardia flights
Greenville to John F Kennedy Intl flights
Myrtle Beach to John F Kennedy Intl flights
Myrtle Beach to Newark flights
Charlotte to Buffalo flights
Charleston to White Plains flights
Myrtle Beach to LaGuardia flights
Augusta to LaGuardia flights
Charlotte to Syracuse flights
Augusta to John F Kennedy Intl flights
Charlotte to Islip flights
Augusta to Newark flights
Charlotte to Albany flights
Charlotte to Rochester flights
Charlotte to White Plains flights
Charleston to Stewart flights
Greenville to Syracuse flights
Columbia to Syracuse flights
Columbia to White Plains flights
Charleston to Albany flights
Charleston to Buffalo flights
Charleston to Islip flights
Myrtle Beach to Syracuse flights
Columbia to Rochester flights
Myrtle Beach to Albany flights
Columbia to Buffalo flights
Hilton Head Island to Newark flights
Greenville to Rochester flights
Greenville to White Plains flights
Savannah to Albany flights
Greenville to Albany flights
Myrtle Beach to Islip flights
Savannah to Syracuse flights
Savannah to Buffalo flights
Columbia to Albany flights
Myrtle Beach to White Plains flights

Top 3 airlines flying from Greenville to Buffalo

Discover the top 3 airlines that operate flights from Greenville to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$311FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$346FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$277Average$352FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.