$155+ Cheap flights from Greenville to Buffalo (GSP - BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BUF
Nov 3 — Nov 101
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Greenville to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Greenville to BuffaloExplore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
Explore the most affordable flight options available from Greenville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:52 pm -
1 stop5h 49m
Mon 11/235:30 am -
1 stop4h 39m
Deal found 9/30![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:55 am -
1 stop7h 06m
Sat 11/76:55 pm -
1 stop3h 59m
Deal found 9/30![American Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:50 pm -
1 stop5h 08m
Thu 11/196:00 am -
1 stop5h 07m
Deal found 10/4![Delta logo]()
$397
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:45 am -
1 stop7h 10m
Mon 1/411:00 am -
2 stops9h 10m
Deal found 9/29![Southwest logo]()
$398
Best flights from Greenville to BuffaloDiscover carefully curated flight deals from Greenville to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
Discover carefully curated flight deals from Greenville to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:39 am -
1 stop6h 47m
Sat 11/710:20 am -
2 stops6h 30m
Deal found 10/1![American Airlines logo]()
$385
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:55 pm -
2 stops7h 20m
Mon 11/234:00 pm -
2 stops7h 00m
Deal found 10/1![Southwest logo]()
$390
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:43 pm -
1 stop4h 03m
Tue 11/36:00 am -
2 stops10h 56m
Deal found 9/30![United Airlines logo]()
$434
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:30 am -
1 stop3h 35m
Tue 10/278:00 am -
2 stops10h 30m
Deal found 10/2![Southwest logo]()
$440
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:20 am -
2 stops7h 50m
Sat 11/76:00 am -
2 stops7h 21m
Deal found 10/1![United Airlines logo]()
$463
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:50 pm -
2 stops11h 10m
Mon 11/234:00 pm -
2 stops7h 00m
Deal found 9/29![Southwest logo]()
$440
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:20 am -
2 stops10h 40m
Sat 11/283:30 pm -
1 stop6h 05m
Deal found 9/30![Southwest logo]()
$468
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/188:05 am -
1 stop6h 45m
Sun 12/206:05 am -
1 stop3h 55m
Deal found 10/2![Southwest logo]()
$493
Last-minute flights from Greenville to BuffaloDiscover last-minute flight deals from Greenville to Buffalo. Data last updated October 4, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Buffalo. Data last updated October 4, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:55 am -
1 stop7h 06m
Sat 11/76:55 pm -
1 stop3h 59m
Deal found 9/30![American Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:50 pm -
1 stop5h 08m
Thu 11/196:00 am -
1 stop5h 07m
Deal found 10/4![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:52 pm -
1 stop5h 49m
Mon 11/235:30 am -
1 stop4h 39m
Deal found 9/30![American Airlines logo]()
$334
One-way flights from Greenville to BuffaloSearch for one-way flight options from Greenville to Buffalo. Find affordable one-way fares based on user searches. Data last updated October 4, 2026.
Search for one-way flight options from Greenville to Buffalo. Find affordable one-way fares based on user searches. Data last updated October 4, 2026.
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop4h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![American Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:28 am -
2 stops24h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Multiple Airlines logo]()
$191
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:34 pm -
1 stop5h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Delta logo]()
$199
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:45 am -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Southwest logo]()
$229
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:20 am -
2 stops8h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Southwest logo]()
$234
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/268:28 pm -
1 stop3h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![American Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:00 am -
1 stop4h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![American Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:40 am -
2 stops7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Southwest logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:32 pm -
3 stops40h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$393
Find flight deals from Greenville to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $334 (American Airlines) |
One-way from | $155 (American Airlines) |
Popular in | March |
Cheapest in | November |
Average price | $436 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
Use the filters below to find and compare flights from Greenville to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleBuffalo
GSP Greenville - BUF Buffalo
GSPBUF
Greenville
Tue 12/1
6:00 am-10:40 am
1 stop4h 40m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
GreenvilleBuffalo
GSP Greenville - BUF Buffalo
GSPBUF
Greenville
Sat 12/26
6:34 pm-12:02 am
1 stop5h 28m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
GreenvilleBuffalo
GSP Greenville - BUF Buffalo
GSPBUF
Greenville
Sat 12/26
12:05 pm-7:00 pm
2 stops6h 55m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$234
Quickest round-trip
GreenvilleBuffalo
GSP Greenville - BUF Buffalo
GSPBUF
Greenville
Sat 12/26
8:28 pm-12:14 am
1 stop3h 46m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$249
GreenvilleBuffalo
GSP Greenville - BUF Buffalo
GSPBUF
Greenville
Wed 10/14
5:40 am-11:16 am
1 stop5h 36m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$344
GreenvilleBuffalo
GSP Greenville - BUF Buffalo
GSPBUF
Greenville
Sat 10/10
6:40 am-2:35 pm
2 stops7h 55m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$349
GreenvilleBuffalo
GSP Greenville - BUF Buffalo
GSPBUF
Greenville
Sun 11/1
10:39 am-5:26 pm
1 stop6h 47m
Buffalo
Sat 11/7
10:20 am-4:50 pm
2 stops6h 30m
$385
GreenvilleBuffalo
GSP Greenville - BUF Buffalo
GSPBUF
Greenville
Sat 11/21
4:55 pm-12:15 am
2 stops7h 20m
Buffalo
Mon 11/23
4:00 pm-11:00 pm
2 stops7h 00m
$390
GreenvilleBuffalo
GSP Greenville - BUF Buffalo
GSPBUF
Greenville
Fri 10/30
7:43 pm-11:46 pm
1 stop4h 03m
Buffalo
Tue 11/3
6:00 am-4:56 pm
2 stops10h 56m
$434
GreenvilleBuffalo
GSP Greenville - BUF Buffalo
GSPBUF
Greenville
Tue 10/20
8:30 am-12:05 pm
1 stop3h 35m
Buffalo
Tue 10/27
8:00 am-6:30 pm
2 stops10h 30m
$440
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Greenville to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Buffalo in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Greenville with our price prediction graph.
GSP-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to Buffalo
What is the cheapest month to book a flight from Greenville to Buffalo?
Currently, November is the cheapest month in which you can book a flight from Greenville to Buffalo (average of $228). Flying from Greenville to Buffalo in March is currently the most expensive (average of $686). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to Buffalo?
Airfare is below average for this route at the moment.
Greenville to Buffalo flights typically cost between $342 and $436 in November.The cheapest round-trip price found within the last 5 days was $334 on American Airlines (Nov 21-Nov 23).
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated October 4, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Greenville to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from Greenville to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Buffalo flight routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Greenville
Popular flights
Alternative routes for Greenville to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 4, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Greenville to Buffalo by cabin class
Find flights from Greenville to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and Buffalo flights
Browse other Greenville and Buffalo flight options. Last updated on October 4, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on October 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Greenville to Buffalo
Discover the top 3 airlines that operate flights from Greenville to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$250 | Average$402 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$302 | Average$433 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$302 | Average$374 | FlexibilityNo cancel fee | On-time71% |