$426+ Cheap flights from Biloxi, MS to Buffalo (BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — BUF
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Biloxi to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Biloxi to Buffalo
Cheapest
Best
Last-minute
Cheapest flights from Biloxi to BuffaloExplore the most affordable flight options available from Biloxi to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Biloxi to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:00 pm -
2 stops8h 50m
Wed 10/286:30 am -
2 stops10h 38m
Deal found 9/9![United Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:42 pm -
1 stop7h 05m
Wed 9/306:30 am -
1 stop7h 42m
Deal found 9/11![American Airlines logo]()
$433
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:59 pm -
1 stop4h 53m
Sat 10/36:05 am -
1 stop4h 16m
Deal found 9/12![Delta logo]()
$438
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:59 pm -
1 stop4h 53m
Tue 9/296:05 am -
1 stop4h 11m
Deal found 9/12![Delta logo]()
$453
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:59 pm -
2 stops7h 58m
Wed 9/302:10 pm -
2 stops8h 58m
Deal found 9/12![Delta logo]()
$463
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:59 pm -
1 stop4h 53m
Thu 10/16:00 am -
2 stops8h 11m
Deal found 9/12![Delta logo]()
$491
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:59 pm -
1 stop4h 53m
Mon 9/286:05 am -
1 stop4h 11m
Deal found 9/12![Delta logo]()
$515
Best flights from Biloxi to BuffaloDiscover carefully curated flight deals from Biloxi to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Biloxi to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:00 pm -
2 stops8h 50m
Wed 10/286:30 am -
2 stops10h 38m
Deal found 9/9![United Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:42 pm -
1 stop7h 05m
Sun 10/45:37 am -
2 stops7h 28m
Deal found 9/12![American Airlines logo]()
$753
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:04 pm -
1 stop4h 55m
Thu 11/266:00 am -
1 stop6h 09m
Deal found 9/11![Delta logo]()
$1,372
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:00 pm -
2 stops8h 50m
Sun 10/47:00 am -
3 stops10h 12m
Deal found 9/12![United Airlines logo]()
$1,045
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/191:54 pm -
2 stops8h 50m
Thu 11/266:00 am -
3 stops11h 08m
Deal found 9/11![United Airlines logo]()
$2,101
Last-minute flights from Biloxi to BuffaloDiscover last-minute flight deals from Biloxi to Buffalo. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from Biloxi to Buffalo. Data last updated September 14, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:59 pm -
1 stop4h 53m
Sat 10/36:05 am -
1 stop4h 16m
Deal found 9/12![Delta logo]()
$438
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:59 pm -
1 stop4h 53m
Tue 9/296:05 am -
1 stop4h 11m
Deal found 9/12![Delta logo]()
$453
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:59 pm -
2 stops7h 58m
Wed 9/302:10 pm -
2 stops8h 58m
Deal found 9/12![Delta logo]()
$463
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:59 pm -
1 stop4h 53m
Thu 10/16:00 am -
2 stops8h 11m
Deal found 9/12![Delta logo]()
$491
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:59 pm -
1 stop4h 53m
Mon 9/286:05 am -
1 stop4h 11m
Deal found 9/12![Delta logo]()
$515
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:42 pm -
1 stop7h 05m
Wed 9/306:30 am -
1 stop7h 42m
Deal found 9/11![American Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:00 pm -
2 stops8h 50m
Wed 10/286:30 am -
2 stops10h 38m
Deal found 9/9![United Airlines logo]()
$426
Find flight deals from Biloxi to Buffalo
Keep the following information in mind while searching for Biloxi to Buffalo flight deals. Data was last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $426 (United Airlines) |
One-way from | $228 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Biloxi to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Biloxi to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GulfportBuffalo
GPT Gulfport Biloxi Regional - BUF Buffalo
GPTBUF
Gulfport Biloxi Regional
Sat 10/24
2:00 pm-11:50 pm
2 stops8h 50m
Buffalo
Wed 10/28
6:30 am-4:08 pm
2 stops10h 38m
$426
GulfportBuffalo
GPT Gulfport Biloxi Regional - BUF Buffalo
GPTBUF
Gulfport Biloxi Regional
Sat 10/3
1:42 pm-9:47 pm
1 stop7h 05m
Buffalo
Sun 10/4
5:37 am-12:05 pm
2 stops7h 28m
$753
GulfportBuffalo
GPT Gulfport Biloxi Regional - BUF Buffalo
GPTBUF
Gulfport Biloxi Regional
Sat 10/3
2:00 pm-11:50 pm
2 stops8h 50m
Buffalo
Sun 10/4
7:00 am-4:12 pm
3 stops10h 12m
$1,045
Quickest round-trip
GulfportBuffalo
GPT Gulfport Biloxi Regional - BUF Buffalo
GPTBUF
Gulfport Biloxi Regional
Thu 11/19
6:04 pm-11:59 pm
1 stop4h 55m
Buffalo
Thu 11/26
6:00 am-11:09 am
1 stop6h 09m
$1,372
GulfportBuffalo
GPT Gulfport Biloxi Regional - BUF Buffalo
GPTBUF
Gulfport Biloxi Regional
Thu 11/19
1:54 pm-11:44 pm
2 stops8h 50m
Buffalo
Thu 11/26
6:00 am-4:08 pm
3 stops11h 08m
$2,101
Sorted by cheapest first
Best time to book a flight from Biloxi to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Biloxi with our price prediction graph.
GPT-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Biloxi to Buffalo
B1L-BUF
GPT-BUF
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated September 14, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Biloxi to Buffalo to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Biloxi to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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Alternative routes for Biloxi to Buffalo
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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Biloxi and Buffalo flights
Browse other Biloxi and Buffalo flight options. Last updated on September 14, 2026.
Popular flight searches
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Biloxi to Buffalo flights
Consider these flights traveling from Biloxi to Buffalo.
Top 5 airlines flying from Biloxi to Buffalo
Discover the top 5 airlines that operate flights from Biloxi to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$105 | Average$240 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$165 | Average$406 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$169 | Average$418 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$193 | Average$398 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$296 | Average$382 | FlexibilityNo cancel fee | On-time63% |