$342+ Cheap flights from Buffalo (BUF) to Biloxi, MS
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — MSY
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Biloxi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Biloxi
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Best
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Cheapest flights from Buffalo to BiloxiExplore the most affordable flight options available from Buffalo to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Buffalo to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:16 pm -
1 stop6h 03m
Mon 11/166:04 pm -
1 stop4h 55m
Deal found 9/15![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop4h 19m
Wed 12/26:09 pm -
1 stop4h 56m
Deal found 9/14![Delta logo]()
$370
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
2 stops8h 09m
Sun 12/136:09 pm -
1 stop4h 56m
Deal found 9/12![Delta logo]()
$428
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:32 am -
1 stop6h 28m
Sun 12/1312:43 pm -
1 stop5h 04m
Deal found 9/12![American Airlines logo]()
$458
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:30 am -
1 stop7h 42m
Thu 10/17:49 am -
1 stop6h 51m
Deal found 9/12![American Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
2 stops8h 11m
Sun 10/45:59 pm -
1 stop4h 53m
Deal found 9/12![Delta logo]()
$469
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/163:53 pm -
2 stops7h 15m
Thu 10/15:59 pm -
1 stop4h 53m
Deal found 9/12![Delta logo]()
$491
Best flights from Buffalo to BiloxiDiscover carefully curated flight deals from Buffalo to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Buffalo to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2012:50 pm -
2 stops10h 17m
Thu 1/216:00 pm -
1 stop4h 55m
Deal found 9/14![Delta logo]()
$342
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:16 pm -
1 stop6h 03m
Mon 11/166:04 pm -
1 stop4h 55m
Deal found 9/15![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1212:50 pm -
2 stops10h 17m
Sat 1/166:00 am -
1 stop6h 16m
Deal found 9/12![Delta logo]()
$346
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:16 pm -
1 stop6h 03m
Wed 12/21:54 pm -
2 stops9h 08m
Deal found 9/14![Delta logo]()
$375
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/146:00 am -
1 stop4h 39m
Sat 1/164:00 pm -
2 stops6h 05m
Deal found 9/12![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
2 stops8h 09m
Sun 12/136:09 pm -
1 stop4h 56m
Deal found 9/12![Delta logo]()
$428
Last-minute flights from Buffalo to BiloxiDiscover last-minute flight deals from Buffalo to Biloxi. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Biloxi. Data last updated September 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:30 am -
1 stop7h 42m
Thu 10/17:49 am -
1 stop6h 51m
Deal found 9/12![American Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/163:53 pm -
2 stops7h 15m
Thu 10/15:59 pm -
1 stop4h 53m
Deal found 9/12![Delta logo]()
$491
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:20 am -
2 stops7h 51m
Thu 10/15:59 pm -
1 stop4h 53m
Deal found 9/12![Delta logo]()
$722
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
2 stops8h 11m
Sun 10/45:59 pm -
1 stop4h 53m
Deal found 9/12![Delta logo]()
$469
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:31 pm -
1 stop7h 01m
Sun 10/47:00 am -
1 stop6h 52m
Deal found 9/15![American Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:00 am -
2 stops10h 12m
Sun 10/45:14 pm -
2 stops15h 15m
Deal found 9/15![United Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:00 am -
2 stops10h 12m
Sat 10/242:00 pm -
2 stops8h 50m
Deal found 9/14![United Airlines logo]()
$545
Find flight deals from Buffalo to Biloxi
Keep the following information in mind while searching for Buffalo to Biloxi flight deals. Data was last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $337 (Delta) |
Popular in | June |
Cheapest in | January |
Average price | $613 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Buffalo to Biloxi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloGulfport
BUF Buffalo - GPT Gulfport Biloxi Regional
BUFGPT
Buffalo
Wed 1/20
12:50 pm-10:07 pm
2 stops10h 17m
Gulfport Biloxi Regional
Thu 1/21
6:00 pm-11:55 pm
1 stop4h 55m
$342
BuffaloGulfport
BUF Buffalo - GPT Gulfport Biloxi Regional
BUFGPT
Buffalo
Fri 11/13
12:16 pm-5:19 pm
1 stop6h 03m
Gulfport Biloxi Regional
Mon 11/16
6:04 pm-11:59 pm
1 stop4h 55m
$344
BuffaloGulfport
BUF Buffalo - GPT Gulfport Biloxi Regional
BUFGPT
Buffalo
Tue 1/12
12:50 pm-10:07 pm
2 stops10h 17m
Gulfport Biloxi Regional
Sat 1/16
6:00 am-1:16 pm
1 stop6h 16m
$346
BuffaloGulfport
BUF Buffalo - GPT Gulfport Biloxi Regional
BUFGPT
Buffalo
Fri 11/20
12:16 pm-5:19 pm
1 stop6h 03m
Gulfport Biloxi Regional
Wed 12/2
1:54 pm-12:02 am
2 stops9h 08m
$375
Quickest round-trip
BuffaloGulfport
BUF Buffalo - GPT Gulfport Biloxi Regional
BUFGPT
Buffalo
Thu 1/14
6:00 am-9:39 am
1 stop4h 39m
Gulfport Biloxi Regional
Sat 1/16
4:00 pm-11:05 pm
2 stops6h 05m
$387
BuffaloGulfport
BUF Buffalo - GPT Gulfport Biloxi Regional
BUFGPT
Buffalo
Thu 12/10
6:00 am-1:09 pm
2 stops8h 09m
Gulfport Biloxi Regional
Sun 12/13
6:09 pm-12:05 am
1 stop4h 56m
$428
Sorted by cheapest first
Best time to book a flight from Buffalo to Biloxi
Have a flexible travel schedule? Discover the best time to fly to Biloxi from Buffalo with our price prediction graph.
BUF-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Biloxi
BUF-B1L
BUF-GPT
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Biloxi
Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated September 15, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Buffalo to Biloxi by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to Biloxi
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Complete your trip
Complete your trip to Biloxi by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to Biloxi by cabin class
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Buffalo and Biloxi flights
Browse other Buffalo and Biloxi flight options. Last updated on September 15, 2026.
Other flights from Buffalo
Browse through other flights departing from Buffalo. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Buffalo to Biloxi flights
Consider these flights traveling from Buffalo to Biloxi.
Top 6 airlines flying from Buffalo to Biloxi
Discover the top 6 airlines that operate flights from Buffalo to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$129 | Average$309 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$217 | Average$278 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$236 | Average$443 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$255 | Average$422 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$262 | Average$336 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$310 | Average$464 | FlexibilityNo cancel fee | On-time63% |