$65+ Cheap flights from Missouri to Boston (BOS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BOS
May 10 — May 171
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to BostonExplore the most affordable flight options available from Missouri to Boston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from Missouri to Boston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am
SGF
- BOS
1 stop6h 49m
Delta
Sat 10/315:45 pm
BOS
- SGF
1 stop5h 47m
Delta
Deal found 4/6![Delta logo]()
$295
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am
SGF
- BOS
1 stop5h 41m
Delta
Sat 9/128:00 am
BOS
- SGF
1 stop7h 45m
Delta
Deal found 4/8![Delta logo]()
$315
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am
SGF
- BOS
1 stop5h 41m
Delta
Wed 9/164:20 pm
BOS
- SGF
1 stop7h 09m
Delta
Deal found 4/6![Delta logo]()
$322
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:00 am
COU
- BOS
1 stop7h 44m
American Airlines
Sat 8/155:29 am
BOS
- COU
1 stop6h 44m
American Airlines
Deal found 4/6![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:28 pm
COU
- BOS
1 stop6h 57m
American Airlines
Wed 5/64:34 pm
BOS
- COU
1 stop5h 56m
American Airlines
Deal found 4/7![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:12 pm
SGF
- BOS
1 stop5h 24m
American Airlines
Tue 8/117:41 am
BOS
- SGF
1 stop5h 47m
American Airlines
Deal found 4/7![American Airlines logo]()
$331
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:30 pm
SGF
- BOS
1 stop8h 36m
Delta
Tue 9/155:45 pm
BOS
- SGF
1 stop5h 44m
Delta
Deal found 4/7![Delta logo]()
$342
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:12 pm
SGF
- BOS
1 stop5h 24m
American Airlines
Thu 7/165:00 am
BOS
- SGF
1 stop6h 05m
American Airlines
Deal found 4/7![American Airlines logo]()
$347
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:33 pm
STL
- BOS
1 stop6h 54m
Frontier
Sat 6/206:00 am
BOS
- STL
2 stops19h 14m
Frontier
Deal found 4/6![Frontier logo]()
$348
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2010:30 am
COU
- BOS
1 stop7h 16m
American Airlines
Wed 6/244:46 pm
BOS
- COU
1 stop7h 00m
American Airlines
Deal found 4/8![American Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:33 pm
STL
- BOS
1 stop6h 54m
Frontier
Sat 8/16:00 am
BOS
- STL
2 stops19h 14m
Frontier
Deal found 4/7![Frontier logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:23 pm
STL
- BOS
1 stop11h 53m
Frontier
Sun 5/312:31 pm
BOS
- STL
2 stops19h 19m
Frontier
Deal found 4/8![Frontier logo]()
$353
Best flights from Missouri to BostonDiscover carefully curated flight deals from Missouri to Boston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from Missouri to Boston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
SGF
- BOS
1 stop8h 12m
Delta
Wed 9/169:05 am
BOS
- SGF
1 stop6h 40m
Delta
Deal found 4/9![Delta logo]()
$295
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:00 am
COU
- BOS
1 stop5h 05m
United Airlines
Sun 7/126:00 am
BOS
- COU
1 stop5h 48m
United Airlines
Deal found 4/7![United Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:50 pm
STL
- BOS
Nonstop2h 30m
Southwest
Fri 5/156:45 pm
BOS
- STL
Nonstop3h 10m
Southwest
Deal found 4/5![Southwest logo]()
$375
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
COU
- BOS
1 stop7h 26m
American Airlines
Sat 5/163:59 pm
BOS
- COU
1 stop6h 30m
American Airlines
Deal found 4/5![American Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:28 pm
JLN
- BOS
1 stop8h 31m
United Airlines
Sun 5/107:30 am
BOS
- JLN
1 stop7h 07m
United Airlines
Deal found 4/6![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:30 pm
STL
- BOS
Nonstop2h 35m
Southwest
Tue 8/255:45 pm
BOS
- STL
Nonstop2h 55m
Southwest
Deal found 4/7![Southwest logo]()
$389
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:06 am
JLN
- BOS
1 stop7h 16m
United Airlines
Wed 5/138:05 am
BOS
- JLN
1 stop6h 32m
United Airlines
Deal found 4/6![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:38 pm
MCI
- BOS
1 stop5h 50m
Delta
Tue 6/94:10 pm
BOS
- MCI
Nonstop3h 33m
Delta
Deal found 4/6![Delta logo]()
$415
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:40 pm
STL
- BOS
Nonstop2h 35m
Southwest
Sun 8/165:30 am
BOS
- STL
Nonstop2h 50m
Southwest
Deal found 4/9![Southwest logo]()
$389
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:00 am
COU
- BOS
1 stop7h 44m
American Airlines
Sat 8/1512:05 pm
BOS
- COU
2 stops7h 40m
American Airlines
Deal found 4/5![American Airlines logo]()
$448
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:30 am
MCI
- BOS
1 stop6h 51m
Delta
Mon 5/412:00 pm
BOS
- MCI
1 stop7h 34m
Delta
Deal found 4/9![Delta logo]()
$415
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:45 am
STL
- BOS
1 stop7h 31m
United Airlines
Sat 5/97:10 pm
BOS
- STL
1 stop5h 47m
United Airlines
Deal found 4/9![United Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:10 pm
MCI
- BOS
Nonstop3h 00m
Southwest
Tue 6/911:35 am
BOS
- MCI
1 stop4h 55m
Southwest
Deal found 4/5![Southwest logo]()
$391
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:10 pm
STL
- BOS
Nonstop2h 30m
Southwest
Sat 7/47:00 am
BOS
- STL
1 stop7h 30m
Southwest
Deal found 4/5![Southwest logo]()
$399
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/129:34 am
MCI
- BOS
Nonstop3h 15m
Delta
Wed 6/176:10 am
BOS
- MCI
Nonstop3h 28m
Delta
Deal found 4/6![Delta logo]()
$439
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:10 pm
COU
- BOS
1 stop5h 48m
United Airlines
Sat 5/911:15 am
BOS
- COU
1 stop10h 34m
United Airlines
Deal found 4/4![United Airlines logo]()
$418
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:10 pm
MCI
- BOS
1 stop5h 00m
Southwest
Tue 6/911:35 am
BOS
- MCI
1 stop4h 55m
Southwest
Deal found 4/5![Southwest logo]()
$400
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:30 pm
SGF
- BOS
1 stop8h 36m
Delta
Sun 9/275:45 am
BOS
- SGF
1 stop6h 16m
Delta
Deal found 4/8![Delta logo]()
$457
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:00 am
COU
- BOS
2 stops10h 28m
United Airlines
Sat 8/157:10 am
BOS
- COU
1 stop8h 20m
United Airlines
Deal found 4/6![United Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/22:10 pm
MCI
- BOS
2 stops6h 10m
Southwest
Thu 6/412:55 pm
BOS
- MCI
1 stop5h 55m
Southwest
Deal found 4/7![Southwest logo]()
$410
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:25 pm
MCI
- BOS
Nonstop3h 05m
Delta
Mon 9/216:50 am
BOS
- MCI
Nonstop3h 41m
Delta
Deal found 4/5![Delta logo]()
$463
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:45 am
STL
- BOS
2 stops9h 35m
United Airlines
Tue 5/52:22 pm
BOS
- STL
2 stops10h 35m
United Airlines
Deal found 4/5![United Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:45 pm
MCI
- BOS
Nonstop3h 10m
Delta
Tue 7/286:10 am
BOS
- MCI
Nonstop3h 31m
Delta
Deal found 4/5![Delta logo]()
$463
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:00 am
MCI
- BOS
Nonstop3h 00m
Southwest
Mon 6/155:45 am
BOS
- MCI
1 stop5h 20m
Southwest
Deal found 4/7![Southwest logo]()
$429
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/59:06 am
JLN
- BOS
1 stop7h 16m
United Airlines
Tue 5/127:30 am
BOS
- JLN
1 stop7h 07m
United Airlines
Deal found 4/7![United Airlines logo]()
$454
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:45 pm
MCI
- BOS
Nonstop3h 10m
Delta
Sun 8/26:10 am
BOS
- MCI
Nonstop3h 31m
Delta
Deal found 4/5![Delta logo]()
$463
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:00 pm
MCI
- BOS
2 stops10h 55m
Southwest
Sat 5/309:25 am
BOS
- MCI
2 stops11h 15m
Southwest
Deal found 4/6![Southwest logo]()
$459
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:54 am
JLN
- BOS
2 stops11h 59m
United Airlines
Wed 7/296:00 am
BOS
- JLN
1 stop8h 22m
United Airlines
Deal found 4/5![United Airlines logo]()
$469
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:30 pm
SGF
- BOS
1 stop6h 19m
Delta
Sun 9/138:00 am
BOS
- SGF
1 stop7h 45m
Delta
Deal found 4/7![Delta logo]()
$476
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/153:35 pm
STL
- BOS
1 stop6h 15m
Southwest
Sat 6/205:50 am
BOS
- STL
Nonstop2h 55m
Southwest
Deal found 4/6![Southwest logo]()
$471
Last-minute flights from Missouri to BostonDiscover last-minute flight deals from Missouri to Boston. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Boston. Data last updated April 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:25 am
STL
- BOS
1 stop13h 06m
Multiple Airlines
Tue 4/286:30 am
BOS
- STL
2 stops25h 20m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:28 pm
COU
- BOS
1 stop6h 57m
American Airlines
Wed 5/64:34 pm
BOS
- COU
1 stop5h 56m
American Airlines
Deal found 4/7![American Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:23 pm
STL
- BOS
1 stop11h 53m
Frontier
Sun 5/312:31 pm
BOS
- STL
2 stops19h 19m
Frontier
Deal found 4/8![Frontier logo]()
$353
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:27 pm
STL
- BOS
1 stop5h 23m
American Airlines
Tue 5/53:17 pm
BOS
- STL
1 stop5h 13m
American Airlines
Deal found 4/6![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:27 pm
STL
- BOS
1 stop5h 23m
American Airlines
Sat 5/93:59 pm
BOS
- STL
1 stop8h 57m
American Airlines
Deal found 4/6![American Airlines logo]()
$360
This KAYAK deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:49 pm
STL
- BOS
Nonstop2h 41m
American Airlines
Thu 5/78:41 am
BOS
- STL
Nonstop3h 13m
American Airlines
Deal found 4/6![American Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:06 am
JLN
- BOS
1 stop6h 10m
United Airlines
Sun 5/107:30 am
BOS
- JLN
1 stop7h 07m
United Airlines
Deal found 4/8![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:35 am
STL
- BOS
2 stops7h 10m
Southwest
Thu 5/145:30 am
BOS
- STL
1 stop6h 20m
Southwest
Deal found 4/6![Southwest logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:35 am
MCI
- BOS
1 stop10h 07m
Multiple Airlines
Wed 5/209:29 am
BOS
- MCI
2 stops9h 00m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:49 pm
STL
- BOS
Nonstop2h 41m
American Airlines
Sun 5/244:00 pm
BOS
- STL
Nonstop3h 10m
American Airlines
Deal found 4/6![American Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:25 am
STL
- BOS
1 stop7h 10m
Southwest
Sun 5/2410:10 am
BOS
- STL
2 stops9h 50m
Southwest
Deal found 4/8![Southwest logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:35 am
MCI
- BOS
2 stops12h 19m
Multiple Airlines
Fri 5/2912:01 pm
BOS
- MCI
1 stop6h 28m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$366
One-way flights from Missouri to BostonSearch for one-way flight options from Missouri to Boston. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from Missouri to Boston. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This Trip.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:27 pm
STL
- BOS
1 stop6h 57m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:24 pm
MCI
- BOS
1 stop12h 25m
Frontier
Deal found 4/5![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:27 pm
STL
- BOS
1 stop6h 57m
Frontier
Deal found 4/6![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
STL
- BOS
1 stop11h 11m
Frontier
Deal found 4/6![Frontier logo]()
$77
This Priceline deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:24 pm
MCI
- BOS
1 stop6h 00m
Frontier
Deal found 4/6![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:27 pm
STL
- BOS
1 stop6h 57m
Frontier
Deal found 4/5![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:24 pm
MCI
- BOS
1 stop12h 28m
Frontier
Deal found 4/9![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:31 pm
STL
- BOS
1 stop12h 21m
Frontier
Deal found 4/9![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:27 pm
STL
- BOS
1 stop13h 25m
Frontier
Deal found 4/6![Frontier logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:41 pm
STL
- BOS
1 stop12h 58m
Frontier
Deal found 4/5![Frontier logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:33 pm
STL
- BOS
1 stop12h 19m
Frontier
Deal found 4/6![Frontier logo]()
$90
This Trip.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:27 pm
STL
- BOS
1 stop6h 57m
Frontier
Deal found 4/7![Frontier logo]()
$91
Find flight deals from Missouri to Boston
Keep the following information in mind while searching for Missouri to Boston flight deals. Data was last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $295 (Delta) |
One-way from | $65 (Trip.com) |
Popular in | February |
Cheapest in | September |
Average price | $465 |
Good round-trip deal | $461 or less |
Good one-way deal | $260 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Boston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Missouri to Boston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SpringfieldBoston
SGF - BOS
SGFBOS
Springfield-Branson
Sat 9/12
6:00 am-3:12 pm
1 stop8h 12m
Boston Logan Intl
Wed 9/16
9:05 am-2:45 pm
1 stop6h 40m
$295
ColumbiaBoston
COU - BOS
COUBOS
Columbia Regional
Wed 7/8
5:00 am-11:05 am
1 stop5h 05m
Boston Logan Intl
Sun 7/12
6:00 am-10:48 am
1 stop5h 48m
$348
JoplinBoston
JLN - BOS
JLNBOS
Joplin
Fri 5/8
2:28 pm-11:59 pm
1 stop8h 31m
Boston Logan Intl
Sun 5/10
7:30 am-1:37 pm
1 stop7h 07m
$364
JoplinBoston
JLN - BOS
JLNBOS
Joplin
Wed 5/6
9:06 am-5:22 pm
1 stop7h 16m
Boston Logan Intl
Wed 5/13
8:05 am-1:37 pm
1 stop6h 32m
$364
St. LouisBoston
STL - BOS
STLBOS
Lambert-St Louis
Wed 5/13
6:50 pm-10:20 pm
Nonstop2h 30m
Boston Logan Intl
Fri 5/15
6:45 pm-8:55 pm
Nonstop3h 10m
$375
St. LouisBoston
STL - BOS
STLBOS
Lambert-St Louis
Wed 5/6
7:45 am-4:16 pm
1 stop7h 31m
Boston Logan Intl
Sat 5/9
7:10 pm-11:57 pm
1 stop5h 47m
$387
St. LouisBoston
STL - BOS
STLBOS
Lambert-St Louis
Thu 8/20
1:30 pm-5:05 pm
Nonstop2h 35m
Boston Logan Intl
Tue 8/25
5:45 pm-7:40 pm
Nonstop2h 55m
$389
Quickest round-trip
St. LouisBoston
STL - BOS
STLBOS
Lambert-St Louis
Wed 8/12
6:40 pm-10:15 pm
Nonstop2h 35m
Boston Logan Intl
Sun 8/16
5:30 am-7:20 am
Nonstop2h 50m
$389
Kansas CityBoston
MCI - BOS
MCIBOS
Kansas City
Mon 6/8
2:10 pm-6:10 pm
Nonstop3h 00m
Boston Logan Intl
Tue 6/9
11:35 am-3:30 pm
1 stop4h 55m
$391
St. LouisBoston
STL - BOS
STLBOS
Lambert-St Louis
Tue 6/23
7:10 pm-10:40 pm
Nonstop2h 30m
Boston Logan Intl
Sat 7/4
7:00 am-1:30 pm
1 stop7h 30m
$399
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Boston
Have a flexible travel schedule? Discover the best time to fly to Boston from Missouri with our price prediction graph.
SGF-BOS
COU-BOS
STL-BOS
JLN-BOS
MCI-BOS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Boston
USMO-BOS
SGF-BOS
COU-BOS
STL-BOS
JLN-BOS
What is the cheapest month to book a flight from Missouri to Boston?
Currently, April is the cheapest month in which you can book a flight from Missouri to Boston (average of $179). Flying from Missouri to Boston in March is currently the most expensive (average of $332). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to BOS?
Find hourly flight availability from Missouri to Boston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 10, 2026.
A simple way to save on the total cost of your ticket is to fly from Missouri to Boston in the evening. If you’re flexible enough to do this you can expect to save up to 47% on your trip compared to booking a flight at noon.
What is the cheapest day to fly from Missouri to Boston?
Use this chart to determine the cheapest time to fly round-trip from Missouri to Boston. Price data was last updated on April 4, 2026.
Travelers seeking maximum savings on their Missouri to Boston flight should consider departing on Saturday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Missouri to Boston
Explore weekly flight availability from Missouri to Boston. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 10, 2026.
The most flights from USMO to BOS are scheduled on a Monday (7 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (3 on average).
How much does it cost to fly round-trip from Missouri to Boston?
Related info for your journey
Find useful and relevant information for your journey from Missouri to Boston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Boston?
Book flights to Boston if you plan to visit one of these locationsMedford
Cambridge
Concord
Hampton Beach
Watertown
Brockton
Seekonk
Cranston
Chelsea
Seabrook
Warwick
Peabody
York Beach
Londonderry
Swansea
Old Orchard Beach
Lincoln
Quincy
Waltham
Lowell
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Boston flight routes
Complete your trip
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Alternative routes for Missouri to Boston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Boston
Explore flights to Boston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 10, 2026.
Complete your trip
Complete your trip to Boston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Boston by cabin class
Find flights from Missouri to Boston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Boston flights
Browse other Missouri and Boston flight options. Last updated on April 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Boston flights
Consider these flights traveling from Missouri to Boston.
Top 6 airlines flying from Missouri to Boston
Discover the top 6 airlines that operate flights from Missouri to Boston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$73 | Average$237 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$125 | Average$200 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$153 | Average$432 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$217 | Average$449 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$459 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$304 | Average$462 | FlexibilityNo cancel fee | On-time63% |