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Biloxi

$181+ Cheap flights from St. Louis (STL) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MSY
Oct 14 — Oct 211
Tue 10/14
Tue 10/21
1 adult, Economy
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Cheap flight deals from St. Louis to Biloxi

Keep the following information in mind while searching for St. Louis to Biloxi flight deals. Data was last updated September 14, 2025.

Round-trip from

$249
(Delta)

One-way from

$181
(Delta)

Popular in

March

Cheapest in

February

Average price

$365
From Lambert-St Louis to Biloxi
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One-way flight from Lambert-St Louis to Biloxi
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Highest demand for flights based on searches. 3% potential increase in price ($11 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from St. Louis to Biloxi

Cheapest flights from St. Louis to Biloxi
Explore the most affordable flight options available from St. Louis to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2025.

This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:00 amSTL - GPT
1 stop5h 45mAmerican Airlines
Sun 10/127:06 pmGPT - STL
1 stop4h 43mAmerican Airlines
Deal found 9/12$274
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:18 amSTL - GPT
1 stop6h 24mAmerican Airlines
Sun 9/2812:12 pmGPT - STL
1 stop7h 21mAmerican Airlines
Deal found 9/13$284
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/198:20 amSTL - GPT
1 stop7h 45mUnited Airlines
Mon 9/225:00 pmGPT - STL
1 stop5h 08mUnited Airlines
Deal found 9/12$309
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:01 amSTL - GPT
1 stop6h 04mAmerican Airlines
Sun 10/127:06 pmGPT - STL
1 stop4h 43mAmerican Airlines
Deal found 9/12$330
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/197:06 amSTL - GPT
1 stop6h 14mDelta
Fri 9/266:04 pmGPT - STL
1 stop5h 20mDelta
Deal found 9/12$354
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/191:03 pmSTL - GPT
2 stops9h 39mAmerican Airlines
Mon 9/225:32 pmGPT - STL
1 stop5h 35mAmerican Airlines
Deal found 9/12$359
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:57 amSTL - GPT
2 stops22h 02mMultiple Airlines
Sun 10/127:55 pmGPT - STL
1 stop24h 26mMultiple Airlines
Deal found 9/12$361
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:15 amSTL - GPT
1 stop7h 10mUnited Airlines
Wed 10/222:00 pmGPT - STL
1 stop4h 57mUnited Airlines
Deal found 9/13$378

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from St. Louis to Biloxi that are best for you.

Fly from

St. Louis

Fly to

Biloxi

Route

Depart

Return

Price

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Wed 2/18

7:30 am-1:37 pm

1 stop6h 07m

Gulfport Biloxi Regional

Sat 2/21

6:00 pm-11:40 pm

1 stop5h 40m

$249

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Wed 2/18

6:04 am-5:33 pm

2 stops11h 29m

Gulfport Biloxi Regional

Sat 2/21

12:46 pm-5:13 pm

1 stop4h 27m

$274

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Fri 9/26

5:18 am-11:42 am

1 stop6h 24m

Gulfport Biloxi Regional

Sun 9/28

12:12 pm-7:33 pm

1 stop7h 21m

$284

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Thu 10/9

7:01 am-1:05 pm

1 stop6h 04m

Gulfport Biloxi Regional

Sun 10/12

7:06 pm-11:49 pm

1 stop4h 43m

$330

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Thu 10/9

10:57 am-8:59 am

2 stops22h 02m

Gulfport Biloxi Regional

Sun 10/12

7:55 pm-8:21 pm

1 stop24h 26m

$361

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Wed 10/8

1:28 pm-10:46 pm

2 stops9h 18m

Gulfport Biloxi Regional

Sun 10/12

7:06 pm-11:49 pm

1 stop4h 43m

$376

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Sat 10/18

11:10 am-7:55 pm

2 stops8h 45m

Gulfport Biloxi Regional

Sun 10/19

5:25 pm-10:00 pm

1 stop4h 35m

$381

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Mon 1/19

7:30 am-1:37 pm

1 stop6h 07m

$181

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Mon 1/19

12:53 pm-9:31 pm

2 stops8h 38m

$186

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Fri 12/26

5:00 am-12:16 pm

1 stop7h 16m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 11 results
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Best time to book a flight from St. Louis to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Biloxi

What is the cheapest month to book a flight from St. Louis to Biloxi?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Biloxi (average of $256). Flying from St. Louis to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to B1L?

Find hourly flight availability from St. Louis to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from St. Louis to Biloxi as you normally would.

What is the cheapest day to fly from St. Louis to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Biloxi. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their St. Louis to Biloxi flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated September 14, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from St. Louis to Biloxi to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,956 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,956 reviews
Delta
8.0
Very good
7,956 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,956 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Biloxi?

    For a flight from St. Louis to Biloxi, you will be flying from Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city. Lambert-St Louis is the only St. Louis airport and it handles 0 outbound flights to Biloxi per day. 6 airlines have flights to Biloxi from Lambert-St Louis on a regular basis.

  • How popular is this St. Louis to Biloxi flight route?

    Flights from Lambert-St Louis to Biloxi have been viewed 4 times in the past calendar month.

  • How long is the flight from St. Louis to Biloxi?

    A quick flight from St. Louis to Biloxi can take about 6h 07m. Delta provides one of the quickest options available for as low as $249. There are 581 mi between St. Louis and Biloxi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from St. Louis to Biloxi one-way?

    The cheapest airlines for a one-way flight from St. Louis to Biloxi are Delta ($181), American Airlines ($186), and United Airlines ($543).

  • What are the cheapest flights from St. Louis to Biloxi?

    Looking for the cheapest flight from St. Louis to Biloxi? While on average our users pay $406, our data indicates the cheapest price to be $240. The most popular route (Lambert-St Louis - Gulfport Biloxi Regional), is priced around $249.

  • Can I find deals for flights from St. Louis to Biloxi that include hotel bookings?

    Yes. In addition to deals on St. Louis to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Biloxi.

  • Can I find deals for business class flights from St. Louis to Biloxi?

    Yes. Cheapflights offers flight deals from St. Louis to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Biloxi?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Biloxi (average of $256). Flying from St. Louis to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from St. Louis to Biloxi

Discover the top 6 airlines that operate flights from St. Louis to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$87Average$147FlexibilityNo cancel feeOn-time88%
FrontierCheapest$127Average$238FlexibilityNo cancel feeOn-time62%
DeltaCheapest$196Average$352FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$212Average$411FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$231Average$353FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$240Average$415FlexibilityNo cancel feeOn-time63%

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