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Biloxi

$183+ Cheap flights from Portland, ME (PWM) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MSY
Jun 20 — Jun 271
Sat 6/20
Sat 6/27
1 adult, Economy
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Cheap flight deals from Portland to Biloxi

Cheapest flights from Portland to Biloxi
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.

This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
PWM
-
GPT
1 stop8h 09m
Delta
Tue 6/1610:06 am
GPT
-
PWM
1 stop6h 46m
Delta
Deal found 5/18$367
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:57 pm
PWM
-
GPT
1 stop7h 04m
American Airlines
Tue 6/210:39 am
GPT
-
PWM
2 stops12h 12m
American Airlines
Deal found 5/20$416
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
PWM
-
GPT
2 stops11h 11m
United Airlines
Sat 5/309:25 am
GPT
-
PWM
2 stops11h 26m
United Airlines
Deal found 5/19$440
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:57 pm
PWM
-
GPT
1 stop7h 04m
American Airlines
Sat 5/307:04 am
GPT
-
PWM
2 stops10h 25m
American Airlines
Deal found 5/19$442
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:57 pm
PWM
-
GPT
1 stop7h 04m
American Airlines
Tue 6/1610:39 am
GPT
-
PWM
1 stop5h 27m
American Airlines
Deal found 5/16$452
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
PWM
-
GPT
1 stop8h 09m
Delta
Tue 6/26:32 am
GPT
-
PWM
1 stop5h 38m
Delta
Deal found 5/19$453

Find flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated May 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$367
(Delta)

One-way from

$183
(Kiwi.com)
Provider with most accurate pricing for Portland-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Gulfport Biloxi Regional flights.
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From Portland to Biloxi
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One-way flight from Portland to Biloxi
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 6/2

6:00 am-1:09 pm

1 stop8h 09m

Gulfport Biloxi Regional

Tue 6/16

10:06 am-5:52 pm

1 stop6h 46m

$367
Quickest round-trip

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 6/2

5:57 pm-12:01 am

1 stop7h 04m

Gulfport Biloxi Regional

Tue 6/16

10:39 am-5:06 pm

1 stop5h 27m

$452

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 6/1

5:57 pm-12:01 am

1 stop7h 04m

Gulfport Biloxi Regional

Sat 6/6

10:39 am-10:29 pm

2 stops10h 50m

$591
Cheapest one-way

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 5/27

5:01 pm-7:10 pm

2 stops27h 09m

$183

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 5/27

11:07 am-7:41 am

3 stops45h 34m

$260
Quickest one-way

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 5/27

5:57 pm-12:01 am

1 stop7h 04m

$387

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 5/26

5:57 pm-12:01 am

1 stop7h 04m

$387

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 5/26

5:15 am-4:11 pm

3 stops11h 56m

$492

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 7/29

1:25 pm-11:56 pm

2 stops11h 31m

$560

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 7/29

11:47 am-10:14 pm

2 stops11h 27m

$710

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/16

Showing 1-10 of 11 resultsSorted by cheapest first
1
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Best time to book a flight from Portland to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    If you book a flight to Biloxi from Portland, you will be flying from Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland. There are 0 flights from Portland to Biloxi per day from 4 different airlines.

  • How long is the flight from Portland, Maine to Biloxi?

    There are many flights that can get you from Portland, Maine to Biloxi in 8h 09m. Fly via Delta to get the fastest option. The distance from Portland, Maine to Biloxi is about 1374 mi.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 4 airlines flying from Portland to Biloxi

Discover the top 4 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$182Average$350FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$286Average$418FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$290Average$476FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$401Average$551FlexibilityNo cancel feeOn-time69%

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