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Biloxi

$411+ Cheap flights from Portland, ME (PWM) to Biloxi, MS

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MSY
May 1 — May 81
Fri 5/1
Fri 5/8
1 adult, Economy
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Cheap flight deals from Portland to Biloxi

Cheapest flights from Portland to Biloxi
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.

This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:57 pm
PWM
-
GPT
1 stop7h 06m
American Airlines
Sat 8/2212:43 pm
GPT
-
PWM
2 stops10h 08m
American Airlines
Deal found 3/30$411
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
PWM
-
GPT
2 stops11h 02m
United Airlines
Wed 8/262:00 pm
GPT
-
PWM
2 stops8h 59m
United Airlines
Deal found 3/27$493
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
PWM
-
GPT
3 stops11h 02m
United Airlines
Sat 8/227:15 am
GPT
-
PWM
2 stops10h 39m
United Airlines
Deal found 3/30$1,190
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:00 am
PWM
-
GPT
3 stops10h 53m
United Airlines
Sat 4/257:10 am
GPT
-
PWM
2 stops10h 18m
United Airlines
Deal found 3/30$2,644
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:21 am
PWM
-
GPT
1 stop5h 03m
Delta
Sat 4/253:00 pm
GPT
-
PWM
1 stop7h 23m
Delta
Deal found 3/30$2,904

Find flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated April 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$411
(American Airlines)
Provider with most accurate pricing for Portland-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Gulfport Biloxi Regional flights.
Search Deals
From Portland to Biloxi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 8/19

1:14 pm-12:03 am

2 stops11h 49m

Gulfport Biloxi Regional

Sat 8/22

12:43 pm-11:51 pm

2 stops10h 08m

$417

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 8/22

6:00 am-4:02 pm

2 stops11h 02m

Gulfport Biloxi Regional

Wed 8/26

2:00 pm-11:59 pm

2 stops8h 59m

$493

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 8/19

6:00 am-4:02 pm

3 stops11h 02m

Gulfport Biloxi Regional

Sat 8/22

7:15 am-6:54 pm

2 stops10h 39m

$1,190

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 4/20

10:00 am-7:53 pm

3 stops10h 53m

Gulfport Biloxi Regional

Sat 4/25

7:10 am-6:28 pm

2 stops10h 18m

$2,644
Quickest round-trip

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 4/20

5:21 am-9:24 am

1 stop5h 03m

Gulfport Biloxi Regional

Sat 4/25

3:00 pm-11:23 pm

1 stop7h 23m

$2,904

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Sorted by cheapest first

Best time to book a flight from Portland to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi

What is the cheapest month to book a flight from Portland, Maine to Biloxi?

Currently, April is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $75). Flying from Portland, Maine to Biloxi in February is currently the most expensive (average of $142). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    If you book a flight to Biloxi from Portland, you will be flying from Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland. There are 0 flights from Portland to Biloxi per day from 5 different airlines.

  • How long is the flight from Portland, Maine to Biloxi?

    There are many flights that can get you from Portland, Maine to Biloxi in 11h 02m. Fly via American Airlines or United Airlines to get the fastest option. The distance from Portland, Maine to Biloxi is about 1374 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Biloxi?

    Currently, April is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $75). Flying from Portland, Maine to Biloxi in February is currently the most expensive (average of $142). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Portland to Biloxi

Discover the top 5 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$87Average$216FlexibilityNo cancel feeOn-time62%
DeltaCheapest$182Average$342FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$286Average$404FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$321Average$454FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$401Average$551FlexibilityNo cancel feeOn-time69%

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