HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Biloxi

$169+ Cheap flights from Buffalo (BUF) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — MSY
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Buffalo to Biloxi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Buffalo to Biloxi

Cheapest flights from Buffalo to Biloxi
Explore the most affordable flight options available from Buffalo to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1612:57 pmBUF - GPT
1 stop5h 05mAmerican Airlines
Sat 12/274:48 pmGPT - BUF
1 stop6h 24mAmerican Airlines
Deal found 12/13$458
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:12 amBUF - GPT
2 stops8h 56mDelta
Sat 12/272:06 pmGPT - BUF
2 stops8h 22mDelta
Deal found 12/13$581
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:00 amBUF - GPT
1 stop4h 59mDelta
Sun 1/45:21 pmGPT - BUF
1 stop5h 29mDelta
Deal found 12/14$629
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1611:35 amBUF - GPT
2 stops10h 47mUnited Airlines
Sat 12/271:57 pmGPT - BUF
2 stops25h 57mUnited Airlines
Deal found 12/14$656
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:15 pmBUF - GPT
1 stop5h 57mAmerican Airlines
Sun 1/44:48 pmGPT - BUF
1 stop6h 11mAmerican Airlines
Deal found 12/15$661
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1612:10 pmBUF - GPT
1 stop6h 06mDelta
Sat 12/202:06 pmGPT - BUF
2 stops8h 22mDelta
Deal found 12/14$786

Find flight deals from Buffalo to Biloxi

Keep the following information in mind while searching for Buffalo to Biloxi flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$421
(Delta)

One-way from

$169
(Delta)

Popular in

January

Cheapest in

March

Average price

$483
Provider with most accurate pricing for Buffalo-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Gulfport Biloxi Regional flights.
Search Deals
From Buffalo to Biloxi
Search Deals
One-way flight from Buffalo to Biloxi
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($189 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($55 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Buffalo to Biloxi that are best for you.

Fly from

Buffalo

Fly to

Biloxi

Route

Depart

Return

Price

BuffaloGulfport

BUF - GPT

BUFGPT

Buffalo

Sat 4/4

4:57 pm-10:19 pm

1 stop6h 22m

Gulfport Biloxi Regional

Fri 4/10

10:04 am-3:59 pm

1 stop4h 55m

$421

BuffaloGulfport

BUF - GPT

BUFGPT

Buffalo

Sat 4/4

4:57 pm-10:19 pm

1 stop6h 22m

Gulfport Biloxi Regional

Sat 4/11

10:04 am-3:59 pm

1 stop4h 55m

$457

BuffaloGulfport

BUF - GPT

BUFGPT

Buffalo

Sat 1/31

8:30 am-7:48 pm

2 stops12h 18m

Gulfport Biloxi Regional

Wed 2/4

5:13 pm-8:29 pm

3 stops26h 16m

$512

BuffaloGulfport

BUF - GPT

BUFGPT

Buffalo

Sat 4/4

2:45 pm-11:56 pm

2 stops10h 11m

Gulfport Biloxi Regional

Sat 4/11

7:27 am-3:39 pm

2 stops7h 12m

$566

BuffaloGulfport

BUF - GPT

BUFGPT

Buffalo

Fri 12/26

6:00 am-9:59 am

1 stop4h 59m

Gulfport Biloxi Regional

Sun 1/4

5:21 pm-11:50 pm

1 stop5h 29m

$629

BuffaloGulfport

BUF - GPT

BUFGPT

Buffalo

Fri 12/26

7:15 pm-12:12 am

1 stop5h 57m

Gulfport Biloxi Regional

Sun 1/4

4:48 pm-11:59 pm

1 stop6h 11m

$661

BuffaloGulfport

BUF - GPT

BUFGPT

Buffalo

Tue 6/9

4:30 pm-10:07 pm

1 stop6h 37m

$169

BuffaloGulfport

BUF - GPT

BUFGPT

Buffalo

Tue 6/9

1:53 pm-5:19 pm

1 stop4h 26m

$169

BuffaloGulfport

BUF - GPT

BUFGPT

Buffalo

Tue 6/9

5:50 pm-1:26 pm

3 stops20h 36m

$445

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Best time to book a flight from Buffalo to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Biloxi

What is the cheapest month to book a flight from Buffalo to Biloxi?

Currently, October is the cheapest month in which you can book a flight from Buffalo to Biloxi (average of $114). Flying from Buffalo to Biloxi in December is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to B1L?

Find hourly flight availability from Buffalo to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

When flying from Buffalo to Biloxi, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 10% versus a flight at noon.

What is the cheapest day to fly from Buffalo to Biloxi?

Use this chart to determine the cheapest time to fly round-trip from Buffalo to Biloxi. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Buffalo to Biloxi flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Buffalo to Biloxi?

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated December 15, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Buffalo to Biloxi by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,052 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Biloxi?

    If you book a flight to Biloxi from Buffalo, you will be flying from Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo. There are 0 flights from Buffalo to Biloxi per day from 5 different airlines.

  • How long is the flight from Buffalo to Biloxi?

    Departing from Buffalo to Biloxi will take you 6h 22m. The distance between Buffalo and Biloxi is about 1036 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Buffalo to Biloxi that include hotel bookings?

    Yes. In addition to deals on Buffalo to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Biloxi.

  • Can I find deals for business class flights from Buffalo to Biloxi?

    Yes. Cheapflights offers flight deals from Buffalo to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Biloxi?

    Currently, October is the cheapest month in which you can book a flight from Buffalo to Biloxi (average of $114). Flying from Buffalo to Biloxi in December is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Buffalo to Biloxi

See prices for flight routes from nearby airports that may be better suited for you.
LaGuardia to Memphis flights
John F Kennedy Intl to Memphis flights
Newark to Memphis flights
Newark to Mobile flights
Newark to Baton Rouge flights
Newark to Gulfport flights
LaGuardia to Jackson flights
LaGuardia to Mobile flights
John F Kennedy Intl to Baton Rouge flights
John F Kennedy Intl to Mobile flights
John F Kennedy Intl to Jackson flights
LaGuardia to Gulfport flights
John F Kennedy Intl to Gulfport flights
Buffalo to Memphis flights
LaGuardia to Baton Rouge flights
Newark to Jackson flights
Rochester to Memphis flights
Stewart to Memphis flights
Buffalo to Mobile flights
Syracuse to Memphis flights
Rochester to Baton Rouge flights
Albany to Memphis flights
Rochester to Mobile flights
Albany to Mobile flights
Syracuse to Gulfport flights
Syracuse to Mobile flights
White Plains to Jackson flights
Buffalo to Gulfport flights
Syracuse to Baton Rouge flights
Albany to Gulfport flights
Albany to Baton Rouge flights
Buffalo to Baton Rouge flights
LaGuardia to Laurel flights
Rochester to Gulfport flights
John F Kennedy Intl to Columbus flights
White Plains to Mobile flights
LaGuardia to Columbus flights
Syracuse to Jackson flights
Newark to Laurel flights
White Plains to Memphis flights
Ithaca to Baton Rouge flights
White Plains to Gulfport flights
Newark to Columbus flights
John F Kennedy Intl to Alexandria flights
Newark to Alexandria flights
Newark to Meridian flights
LaGuardia to Alexandria flights
Islip to Memphis flights
White Plains to Alexandria flights
Stewart to Jackson flights

Top 5 airlines flying from Buffalo to Biloxi

Discover the top 5 airlines that operate flights from Buffalo to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$124Average$251FlexibilityNo cancel feeOn-time62%
DeltaCheapest$236Average$380FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$452FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$271Average$376FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$352Average$497FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.