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Biloxi

$322+ Cheap flights from Portland, ME (PWM) to Biloxi, MS

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MSY
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated January 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$322
(Delta)
Provider with most accurate pricing for Portland-Gulfport Biloxi Regional flight deals.
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Provider most trusted by Cheapflights users for Portland-Gulfport Biloxi Regional flights.
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From Portland to Biloxi
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Find flight deals from Portland to Biloxi

Cheapest flights from Portland to Biloxi
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2312:43 pmPWM - GPT
2 stops10h 10mDelta
Sat 1/243:00 pmGPT - PWM
1 stop6h 27mDelta
Deal found 1/7$322
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2312:40 pmPWM - GPT
2 stops11h 01mAmerican Airlines
Sat 1/246:32 amGPT - PWM
2 stops7h 59mAmerican Airlines
Deal found 1/7$328
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/248:40 amPWM - GPT
2 stops12h 08mUnited Airlines
Wed 1/285:13 pmGPT - PWM
2 stops20h 26mUnited Airlines
Deal found 1/6$608
This American Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/912:40 pmPWM - GPT
2 stops11h 01mAmerican Airlines
Sun 1/111:45 pmGPT - PWM
1 stop7h 22mAmerican Airlines
Deal found 1/8$666
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/412:51 pmPWM - GPT
2 stops10h 24mDelta
Sat 4/113:00 pmGPT - PWM
1 stop7h 22mDelta
Deal found 1/7$684
This Delta deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/1012:51 pmPWM - GPT
2 stops10h 02mDelta
Sun 1/114:00 pmGPT - PWM
1 stop5h 27mDelta
Deal found 1/8$738
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/238:40 amPWM - GPT
2 stops12h 08mUnited Airlines
Sat 1/247:00 amGPT - PWM
3 stops15h 30mUnited Airlines
Deal found 1/7$847

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.

Fly from

Portland

Fly to

Biloxi

Route

Depart

Return

Price

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Fri 1/23

12:43 pm-9:53 pm

2 stops10h 10m

Gulfport Biloxi Regional

Sat 1/24

3:00 pm-10:27 pm

1 stop6h 27m

$322

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Fri 1/23

12:40 pm-10:41 pm

2 stops11h 01m

Gulfport Biloxi Regional

Sat 1/24

6:32 am-3:31 pm

2 stops7h 59m

$328

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 1/24

8:40 am-7:48 pm

2 stops12h 08m

Gulfport Biloxi Regional

Wed 1/28

5:13 pm-2:39 pm

2 stops20h 26m

$608

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 4/4

12:51 pm-10:15 pm

2 stops10h 24m

Gulfport Biloxi Regional

Sat 4/11

3:00 pm-11:22 pm

1 stop7h 22m

$684

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Fri 1/23

8:40 am-7:48 pm

2 stops12h 08m

Gulfport Biloxi Regional

Sat 1/24

7:00 am-11:30 pm

3 stops15h 30m

$847

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 4/18

7:33 pm-7:53 pm

2 stops25h 20m

Gulfport Biloxi Regional

Fri 4/24

5:15 pm-3:16 pm

3 stops21h 01m

$981

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/7

Best time to book a flight from Portland to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi

What is the cheapest month to book a flight from Portland, Maine to Biloxi?

Currently, March is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $61). Flying from Portland, Maine to Biloxi in December is currently the most expensive (average of $138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    If you book a flight to Biloxi from Portland, you will be flying from Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland. There are 0 flights from Portland to Biloxi per day from 5 different airlines.

  • How long is the flight from Portland, Maine to Biloxi?

    There are many flights that can get you from Portland, Maine to Biloxi in 10h 10m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance from Portland, Maine to Biloxi is about 1374 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Biloxi?

    Currently, March is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $61). Flying from Portland, Maine to Biloxi in December is currently the most expensive (average of $138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Portland to Biloxi

Discover the top 5 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$108Average$216FlexibilityNo cancel feeOn-time62%
DeltaCheapest$187Average$389FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$246Average$438FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$271Average$400FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$321Average$490FlexibilityNo cancel feeOn-time63%

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