$329+ Cheap flights from Portland, ME (PWM) to Biloxi, MS
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MSY
Aug 17 — Aug 241
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Biloxi with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Biloxi
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Best
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Cheapest flights from Portland to BiloxiExplore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:05 am
PWM
- GPT
1 stop7h 12m
American Airlines
Wed 8/191:50 pm
GPT
- PWM
1 stop7h 10m
American Airlines
Deal found 7/15![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:30 am
PWM
- GPT
2 stops7h 33m
Delta
Wed 8/191:48 pm
GPT
- PWM
2 stops10h 11m
Delta
Deal found 7/15![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:11 am
PWM
- GPT
1 stop6h 18m
American Airlines
Sun 12/64:38 pm
GPT
- PWM
1 stop4h 56m
American Airlines
Deal found 7/15![American Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:05 am
PWM
- GPT
1 stop7h 58m
Delta
Thu 8/201:48 pm
GPT
- PWM
2 stops10h 11m
Delta
Deal found 7/16![Delta logo]()
$419
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am
PWM
- GPT
2 stops8h 12m
American Airlines
Sat 9/261:42 pm
GPT
- PWM
1 stop7h 31m
American Airlines
Deal found 7/15![American Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
PWM
- GPT
2 stops7h 40m
Delta
Sat 8/14:00 pm
GPT
- PWM
1 stop6h 14m
Delta
Deal found 7/17![Delta logo]()
$472
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:05 am
PWM
- GPT
1 stop7h 12m
American Airlines
Thu 8/201:50 pm
GPT
- PWM
1 stop7h 10m
American Airlines
Deal found 7/16![American Airlines logo]()
$491
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am
PWM
- GPT
2 stops8h 35m
Delta
Sun 12/62:15 pm
GPT
- PWM
2 stops7h 51m
Delta
Deal found 7/15![Delta logo]()
$499
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:01 pm
PWM
- GPT
2 stops26h 44m
Breeze Airways
Fri 8/75:31 pm
GPT
- PWM
1 stop25h 55m
Breeze Airways
Deal found 7/15![Breeze Airways logo]()
$506
Best flights from Portland to BiloxiDiscover carefully curated flight deals from Portland to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2026.
Discover carefully curated flight deals from Portland to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2026.
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
PWM
- GPT
2 stops7h 40m
Delta
Sat 8/14:00 pm
GPT
- PWM
1 stop6h 14m
Delta
Deal found 7/17![Delta logo]()
$472
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am
PWM
- GPT
2 stops11h 07m
United Airlines
Wed 11/185:04 pm
GPT
- PWM
2 stops29h 19m
United Airlines
Deal found 7/16![United Airlines logo]()
$553
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
PWM
- GPT
2 stops7h 40m
Delta
Mon 8/31:48 pm
GPT
- PWM
2 stops8h 42m
Delta
Deal found 7/15![Delta logo]()
$515
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
PWM
- GPT
2 stops7h 40m
Delta
Thu 8/66:00 pm
GPT
- PWM
2 stops29h 59m
Delta
Deal found 7/15![Delta logo]()
$661
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/99:45 am
PWM
- GPT
2 stops10h 57m
United Airlines
Tue 1/125:15 pm
GPT
- PWM
2 stops14h 04m
United Airlines
Deal found 7/12![United Airlines logo]()
$744
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:52 pm
PWM
- GPT
2 stops21h 13m
Delta
Wed 8/51:48 pm
GPT
- PWM
2 stops10h 11m
Delta
Deal found 7/15![Delta logo]()
$680
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:00 am
PWM
- GPT
2 stops12h 12m
Delta
Wed 8/51:48 pm
GPT
- PWM
2 stops10h 11m
Delta
Deal found 7/15![Delta logo]()
$709
Last-minute flights from Portland to BiloxiDiscover last-minute flight deals from Portland to Biloxi. Data last updated July 18, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Biloxi. Data last updated July 18, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:01 pm
PWM
- GPT
2 stops26h 44m
Breeze Airways
Fri 8/75:31 pm
GPT
- PWM
1 stop25h 55m
Breeze Airways
Deal found 7/15![Breeze Airways logo]()
$506
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:01 pm
PWM
- GPT
2 stops26h 44m
Breeze Airways
Sun 8/27:25 pm
GPT
- PWM
1 stop12h 47m
Breeze Airways
Deal found 7/15![Breeze Airways logo]()
$512
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
PWM
- GPT
2 stops7h 40m
Delta
Sat 8/14:00 pm
GPT
- PWM
1 stop6h 14m
Delta
Deal found 7/17![Delta logo]()
$472
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
PWM
- GPT
2 stops7h 40m
Delta
Mon 8/31:48 pm
GPT
- PWM
2 stops8h 42m
Delta
Deal found 7/15![Delta logo]()
$515
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:01 pm
PWM
- GPT
1 stop6h 55m
American Airlines
Tue 8/47:04 am
GPT
- PWM
1 stop5h 36m
American Airlines
Deal found 7/15![American Airlines logo]()
$518
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:05 am
PWM
- GPT
1 stop7h 12m
American Airlines
Wed 8/191:50 pm
GPT
- PWM
1 stop7h 10m
American Airlines
Deal found 7/15![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:30 am
PWM
- GPT
2 stops7h 33m
Delta
Wed 8/191:48 pm
GPT
- PWM
2 stops10h 11m
Delta
Deal found 7/15![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:05 am
PWM
- GPT
1 stop7h 58m
Delta
Thu 8/201:48 pm
GPT
- PWM
2 stops10h 11m
Delta
Deal found 7/16![Delta logo]()
$419
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:05 am
PWM
- GPT
1 stop7h 12m
American Airlines
Thu 8/201:50 pm
GPT
- PWM
1 stop7h 10m
American Airlines
Deal found 7/16![American Airlines logo]()
$491
One-way flights from Portland to BiloxiSearch for one-way flight options from Portland to Biloxi. Find affordable one-way fares based on user searches. Data last updated July 18, 2026.
Search for one-way flight options from Portland to Biloxi. Find affordable one-way fares based on user searches. Data last updated July 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:01 pm
PWM
- GPT
2 stops26h 44m
Breeze Airways
Deal found 7/14![Breeze Airways logo]()
$359
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:01 pm
PWM
- GPT
1 stop6h 55m
American Airlines
Deal found 7/14![American Airlines logo]()
$387
This deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:01 pm
PWM
- GPT
1 stop6h 55m
American Airlines
Deal found 7/14![American Airlines logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:01 pm
PWM
- GPT
3 stops39h 40m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$478
Find flight deals from Portland to Biloxi
Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated July 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $329 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PortlandGulfport
PWM - GPT
PWMGPT
Portland
Thu 7/30
6:25 am-1:05 pm
2 stops7h 40m
Gulfport Biloxi Regional
Sat 8/1
4:00 pm-11:14 pm
1 stop6h 14m
$472
PortlandGulfport
PWM - GPT
PWMGPT
Portland
Thu 7/30
6:25 am-1:05 pm
2 stops7h 40m
Gulfport Biloxi Regional
Mon 8/3
1:48 pm-11:30 pm
2 stops8h 42m
$515
PortlandGulfport
PWM - GPT
PWMGPT
Portland
Sat 11/14
6:00 am-4:07 pm
2 stops11h 07m
Gulfport Biloxi Regional
Wed 11/18
5:04 pm-11:23 pm
2 stops29h 19m
$553
PortlandGulfport
PWM - GPT
PWMGPT
Portland
Thu 7/30
6:25 am-1:05 pm
2 stops7h 40m
Gulfport Biloxi Regional
Thu 8/6
6:00 pm-12:59 am
2 stops29h 59m
$661
PortlandGulfport
PWM - GPT
PWMGPT
Portland
Mon 7/27
4:52 pm-1:05 pm
2 stops21h 13m
Gulfport Biloxi Regional
Wed 8/5
1:48 pm-12:59 am
2 stops10h 11m
$680
PortlandGulfport
PWM - GPT
PWMGPT
Portland
Fri 7/31
6:00 am-5:12 pm
2 stops12h 12m
Gulfport Biloxi Regional
Wed 8/5
1:48 pm-12:59 am
2 stops10h 11m
$709
PortlandGulfport
PWM - GPT
PWMGPT
Portland
Sat 1/9
9:45 am-7:42 pm
2 stops10h 57m
Gulfport Biloxi Regional
Tue 1/12
5:15 pm-8:19 am
2 stops14h 04m
$744
Cheapest one-way
PortlandGulfport
PWM - GPT
PWMGPT
Portland
Wed 7/22
5:01 pm-6:45 pm
2 stops26h 44m
$359
Quickest one-way
PortlandGulfport
PWM - GPT
PWMGPT
Portland
Wed 7/22
6:01 pm-11:56 pm
1 stop6h 55m
$387
PortlandGulfport
PWM - GPT
PWMGPT
Portland
Thu 7/23
6:01 pm-11:56 pm
1 stop6h 55m
$434
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Portland to Biloxi
Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
PWM-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Biloxi
PWM-B1L
PWM-GPT
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to Biloxi
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Biloxi by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Biloxi by cabin class
Find flights from Portland to Biloxi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Biloxi flights
Browse other Portland and Biloxi flight options. Last updated on July 18, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on July 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Biloxi flights
Consider these flights traveling from Portland to Biloxi.
Top 4 airlines flying from Portland to Biloxi
Discover the top 4 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$182 | Average$380 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$287 | Average$436 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$323 | Average$496 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$451 | Average$556 | FlexibilityNo cancel fee | On-time69% |