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Biloxi

$240+ Cheap flights from Portland, ME (PWM) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MSY
Aug 31 — Sep 71
Mon 8/31
Mon 9/7
1 adult, Economy
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Cheap flight deals from Portland to Biloxi

Cheapest flights from Portland to Biloxi
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.

This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:50 pm
PWM
-
GPT
2 stops10h 12m
Delta
Thu 11/264:00 pm
GPT
-
PWM
1 stop6h 33m
Delta
Deal found 7/28$344
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/305:52 am
PWM
-
GPT
2 stops11h 20m
United Airlines
Sun 9/62:00 pm
GPT
-
PWM
2 stops8h 59m
United Airlines
Deal found 7/31$446
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:30 am
PWM
-
GPT
2 stops8h 47m
American Airlines
Mon 8/171:50 pm
GPT
-
PWM
1 stop7h 10m
American Airlines
Deal found 7/28$473
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:05 am
PWM
-
GPT
1 stop7h 58m
Delta
Fri 9/44:00 pm
GPT
-
PWM
1 stop6h 13m
Delta
Deal found 7/30$489
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:24 pm
PWM
-
GPT
1 stop5h 35m
American Airlines
Sun 9/67:05 am
GPT
-
PWM
1 stop7h 37m
American Airlines
Deal found 7/31$494
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:01 pm
PWM
-
GPT
1 stop6h 55m
American Airlines
Mon 8/310:36 am
GPT
-
PWM
1 stop5h 33m
American Airlines
Deal found 7/27$512
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 am
PWM
-
GPT
2 stops11h 47m
Delta
Sat 8/14:00 pm
GPT
-
PWM
1 stop6h 14m
Delta
Deal found 7/28$515

Find flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated August 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$344
(Delta)

One-way from

$240
(United Airlines)
Provider with most accurate pricing for Portland-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Gulfport Biloxi Regional flights.
Search Deals
From Portland to Biloxi
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One-way flight from Portland to Biloxi
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Thu 11/19

12:50 pm-10:02 pm

2 stops10h 12m

Gulfport Biloxi Regional

Thu 11/26

4:00 pm-11:33 pm

1 stop6h 33m

$344
Quickest round-trip

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sun 8/30

7:24 pm-11:59 pm

1 stop5h 35m

Gulfport Biloxi Regional

Sun 9/6

7:05 am-3:42 pm

1 stop7h 37m

$494

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 8/11

7:05 am-1:17 pm

1 stop7h 12m

Gulfport Biloxi Regional

Mon 8/17

1:50 pm-10:00 pm

1 stop7h 10m

$497

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 11/14

8:45 am-7:34 pm

2 stops11h 49m

Gulfport Biloxi Regional

Wed 11/18

7:00 am-9:51 pm

2 stops13h 51m

$553

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Thu 11/19

5:30 am-1:18 pm

2 stops8h 48m

Gulfport Biloxi Regional

Thu 11/26

7:00 am-7:02 pm

3 stops11h 02m

$1,171
Cheapest one-way

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 10/6

5:15 am-1:25 pm

2 stops9h 10m

$240

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 10/6

6:01 am-1:01 pm

1 stop8h 00m

$259
Quickest one-way

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 10/6

7:03 am-12:50 pm

1 stop6h 47m

$472

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Sorted by cheapest first

Best time to book a flight from Portland to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated August 1, 2026.
Read reviews from past customers who have flown American Airlines from Portland to Biloxi. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,845 reviews

Boarding

7.5

Entertainment

6.8

Crew

7.9

Food

6.4

Comfort

7.2

Overall

7.1

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go
American Airlines
7.1
Good
11,845 reviews
American Airlines
7.1
Good
11,845 reviews

Boarding

7.5

Entertainment

6.8

Crew

7.9

Food

6.4

Comfort

7.2

Overall

7.1

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    If you book a flight to Biloxi from Portland, you will be flying from Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland. There are 0 flights from Portland to Biloxi per day from 4 different airlines.

  • How long is the flight from Portland, Maine to Biloxi?

    There are many flights that can get you from Portland, Maine to Biloxi in 8h 47m. Fly via Delta, United Airlines, or American Airlines to get the fastest option. The distance from Portland, Maine to Biloxi is about 1374 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 4 airlines flying from Portland to Biloxi

Discover the top 4 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$182Average$397FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$290Average$484FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$296Average$451FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$451Average$556FlexibilityNo cancel feeOn-time69%

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