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Biloxi

Cheap flights from Portland, ME (PWM) to Biloxi, MS

PWM — MSY
Mar 20 — Mar 271
Fri 3/20
Fri 3/27
1 adult, Economy
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Find flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated February 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$585
(Delta)

Popular in

November

Cheapest in

August

Average price

$437
Provider with most accurate pricing for Boston Logan Intl-Gulfport Biloxi Regional flight deals.
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Provider most trusted by Cheapflights users for Boston Logan Intl-Gulfport Biloxi Regional flights.
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From Portland to Biloxi
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Highest demand for flights based on searches. 11% potential increase in price ($48 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in February 2026
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Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi

What is the cheapest month to book a flight from Portland, Maine to Biloxi?

Currently, March is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $61). Flying from Portland, Maine to Biloxi in December is currently the most expensive (average of $138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    If you book a flight to Biloxi from Portland, you will be flying from Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland. There are 0 flights from Portland to Biloxi per day from 5 different airlines.

  • How long is the flight from Portland, Maine to Biloxi?

    There are many flights that can get you from Portland, Maine to Biloxi in 10h 59m. Fly via Delta or American Airlines to get the fastest option. The distance from Portland, Maine to Biloxi is about 1374 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Biloxi?

    Currently, March is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $61). Flying from Portland, Maine to Biloxi in December is currently the most expensive (average of $138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 5 airlines flying from Portland to Biloxi

Discover the top 5 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$87Average$216FlexibilityNo cancel feeOn-time62%
DeltaCheapest$182Average$353FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$246Average$438FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$271Average$395FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$290Average$456FlexibilityNo cancel feeOn-time63%

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