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Biloxi

$309+ Cheap flights from Portland, ME (PWM) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MSY
Sep 14 — Sep 211
Mon 9/14
Mon 9/21
1 adult, Economy
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Cheap flight deals from Portland to Biloxi

Cheapest flights from Portland to Biloxi
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 15, 2026.

This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop8h 08m
Sat 11/146:25 am -
1 stop5h 38m
Deal found 8/12$339
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:15 am -
2 stops9h 09m
Tue 9/14:59 pm -
2 stops27h 24m
Deal found 8/13$573
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:15 am -
2 stops11h 57m
Tue 8/187:08 am -
2 stops10h 21m
Deal found 8/12$607
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
1 stop7h 05m
Thu 9/241:42 pm -
1 stop7h 31m
Deal found 8/10$646
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am -
2 stops11h 12m
Mon 8/172:00 pm -
2 stops8h 59m
Deal found 8/12$705
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:45 pm -
2 stops22h 39m
Mon 8/172:00 pm -
2 stops8h 59m
Deal found 8/12$914

Find flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated August 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$339
(Delta)

One-way from

$309
(American Airlines)
Provider with most accurate pricing for Portland-Gulfport Biloxi Regional flight deals.
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Provider most trusted by Cheapflights users for Portland-Gulfport Biloxi Regional flights.
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From Portland to Biloxi
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One-way flight from Portland to Biloxi
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 15, 2026.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PortlandGulfport

PWM Portland - GPT Gulfport Biloxi Regional

PWMGPT

Portland

Wed 11/11

6:00 am-1:08 pm

1 stop8h 08m

Gulfport Biloxi Regional

Sat 11/14

6:25 am-1:03 pm

1 stop5h 38m

$339

PortlandGulfport

PWM Portland - GPT Gulfport Biloxi Regional

PWMGPT

Portland

Wed 11/11

7:10 am-1:28 pm

1 stop7h 18m

Gulfport Biloxi Regional

Sat 11/14

2:02 pm-9:36 pm

1 stop6h 34m

$339
Cheapest one-way
Quickest one-way

PortlandGulfport

PWM Portland - GPT Gulfport Biloxi Regional

PWMGPT

Portland

Fri 9/4

7:05 am-1:17 pm

1 stop7h 12m

$309

PortlandGulfport

PWM Portland - GPT Gulfport Biloxi Regional

PWMGPT

Portland

Fri 9/4

9:49 am-7:38 pm

3 stops10h 49m

$654

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Sorted by cheapest first

Best time to book a flight from Portland to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi

No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    If you book a flight to Biloxi from Portland, you will be flying from Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland. There are 0 flights from Portland to Biloxi per day from 4 different airlines.

  • How long is the flight from Portland, Maine to Biloxi?

    There are many flights that can get you from Portland, Maine to Biloxi in 7h 18m. Fly via Delta or American Airlines to get the fastest option. The distance from Portland, Maine to Biloxi is about 1374 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 4 airlines flying from Portland to Biloxi

Discover the top 4 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$182Average$397FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$290Average$484FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$305Average$455FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$451Average$556FlexibilityNo cancel feeOn-time69%

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