HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Biloxi

$243+ Cheap flights from Portland, ME (PWM) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MSY
Jul 31 — Aug 71
Fri 7/31
Fri 8/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to Biloxi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Portland to Biloxi

Cheapest flights from Portland to Biloxi
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2026.

This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:25 am
PWM
-
GPT
2 stops8h 41m
Delta
Wed 7/86:30 am
GPT
-
PWM
2 stops9h 20m
Delta
Deal found 6/29$511
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am
PWM
-
GPT
2 stops11h 07m
United Airlines
Tue 11/175:04 pm
GPT
-
PWM
2 stops15h 01m
United Airlines
Deal found 6/29$534
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:58 pm
PWM
-
GPT
1 stop7h 01m
American Airlines
Wed 7/87:04 am
GPT
-
PWM
2 stops10h 30m
American Airlines
Deal found 6/29$611
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:55 pm
PWM
-
GPT
1 stop7h 46m
Delta
Sun 7/56:30 am
GPT
-
PWM
1 stop5h 30m
Delta
Deal found 6/29$667
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:01 pm
PWM
-
GPT
1 stop6h 55m
American Airlines
Sun 7/57:04 am
GPT
-
PWM
1 stop5h 36m
American Airlines
Deal found 6/27$692

Find flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated July 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$534
(United Airlines)

One-way from

$243
(Delta)
Provider with most accurate pricing for Portland-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Gulfport Biloxi Regional flights.
Search Deals
From Portland to Biloxi
Search Deals
One-way flight from Portland to Biloxi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2026.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 11/14

6:00 am-4:07 pm

2 stops11h 07m

Gulfport Biloxi Regional

Tue 11/17

5:04 pm-9:05 am

2 stops15h 01m

$534
Cheapest one-way
Quickest one-way

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Thu 8/6

6:00 am-1:03 pm

2 stops8h 03m

$243

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 8/5

6:30 am-5:15 pm

2 stops11h 45m

$315

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/29

Sorted by cheapest first

Best time to book a flight from Portland to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    If you book a flight to Biloxi from Portland, you will be flying from Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland. There are 0 flights from Portland to Biloxi per day from 4 different airlines.

  • How long is the flight from Portland, Maine to Biloxi?

    There are many flights that can get you from Portland, Maine to Biloxi in 11h 07m. Fly via United Airlines to get the fastest option. The distance from Portland, Maine to Biloxi is about 1374 mi.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Portland to Biloxi

Discover the top 4 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$182Average$361FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$288Average$436FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$323Average$496FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$451Average$556FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.