HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Biloxi

$417+ Cheap flights from Portland, ME (PWM) to Biloxi, MS

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MSY
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to Biloxi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Portland to Biloxi

Cheapest flights from Portland to Biloxi
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1812:48 pmPWM - GPT
2 stops10h 19mDelta
Sat 11/223:30 pmGPT - PWM
1 stop5h 49mDelta
Deal found 11/3$417
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:00 amPWM - GPT
2 stops8h 20mAmerican Airlines
Sat 11/227:15 amGPT - PWM
2 stops8h 23mAmerican Airlines
Deal found 11/3$566
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:21 pmPWM - GPT
2 stops7h 36mAmerican Airlines
Fri 12/51:40 pmGPT - PWM
1 stop6h 57mAmerican Airlines
Deal found 11/3$592
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/249:54 amPWM - GPT
2 stops12h 42mUnited Airlines
Mon 12/15:15 pmGPT - PWM
2 stops20h 04mUnited Airlines
Deal found 11/4$599
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:35 amPWM - GPT
2 stops8h 33mDelta
Mon 12/12:53 pmGPT - PWM
1 stop6h 21mDelta
Deal found 11/4$684
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:00 amPWM - GPT
3 stops16h 36mUnited Airlines
Sat 11/225:15 pmGPT - PWM
2 stops15h 49mUnited Airlines
Deal found 11/3$731
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:30 amPWM - GPT
3 stops11h 32mUnited Airlines
Fri 12/51:57 pmGPT - PWM
2 stops8h 12mUnited Airlines
Deal found 11/3$989

Cheap flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated November 4, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$417
(Delta)

Popular in

June

Cheapest in

January

Average price

$674
Provider with most accurate pricing for Portland-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Gulfport Biloxi Regional flights.
Search Deals
From Portland to Biloxi
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.

Fly from

Portland

Fly to

Biloxi

Route

Depart

Return

Price

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 11/18

12:48 pm-10:07 pm

2 stops10h 19m

Gulfport Biloxi Regional

Sat 11/22

3:30 pm-10:19 pm

1 stop5h 49m

$417

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 12/1

5:21 pm-11:57 pm

2 stops7h 36m

Gulfport Biloxi Regional

Fri 12/5

1:40 pm-11:37 pm

2 stops8h 57m

$597

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 11/24

9:54 am-9:36 pm

2 stops12h 42m

Gulfport Biloxi Regional

Mon 12/1

5:15 pm-2:19 pm

2 stops20h 04m

$599

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 11/24

6:35 am-2:08 pm

2 stops8h 33m

Gulfport Biloxi Regional

Mon 12/1

2:53 pm-10:14 pm

1 stop6h 21m

$684

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 11/18

6:00 am-9:36 pm

3 stops16h 36m

Gulfport Biloxi Regional

Sat 11/22

5:15 pm-10:04 am

2 stops15h 49m

$731

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 11/18

7:02 am-1:20 pm

1 stop7h 18m

Gulfport Biloxi Regional

Sat 11/22

12:48 pm-10:33 pm

1 stop8h 45m

$816

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 12/1

5:30 am-4:02 pm

3 stops11h 32m

Gulfport Biloxi Regional

Fri 12/5

1:57 pm-11:09 pm

2 stops8h 12m

$989

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Best time to book a flight from Portland to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi

What is the cheapest month to book a flight from Portland, Maine to Biloxi?

Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $66). Flying from Portland, Maine to Biloxi in August is currently the most expensive (average of $123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to B1L?

Find hourly flight availability from Portland to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2025.

It’s typically best to fly out from Portland, Maine to Biloxi in the evening. Doing so could potentially save you 65% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from Portland, Maine to Biloxi?

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    If you book a flight to Biloxi from Portland, you will be flying from Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland. There are 0 flights from Portland to Biloxi per day from 5 different airlines.

  • How long is the flight from Portland, Maine to Biloxi?

    There are many flights that can get you from Portland, Maine to Biloxi in 7h 36m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance from Portland, Maine to Biloxi is about 1374 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Biloxi?

    Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $66). Flying from Portland, Maine to Biloxi in August is currently the most expensive (average of $123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 5 airlines flying from Portland to Biloxi

Discover the top 5 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$108Average$216FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$246Average$485FlexibilityNo cancel feeOn-time69%
DeltaCheapest$256Average$409FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$271Average$397FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$321Average$494FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.