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Biloxi

$169+ Cheap flights from Portland, ME (PWM) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MSY
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated September 11, 2025.

Round-trip from

$522
(United Airlines)

One-way from

$169
(Delta)

Popular in

June

Cheapest in

May

Average price

$523
From Portland to Biloxi
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One-way flight from Portland to Biloxi
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Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Portland to Biloxi

Cheapest flights from Portland to Biloxi
Explore the most affordable flight options available from Portland to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:45 amPWM - GPT
2 stops11h 27mUnited Airlines
Wed 10/17:00 amGPT - PWM
2 stops15h 13mUnited Airlines
Deal found 9/9$522
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:10 pmPWM - GPT
1 stop6h 32mAmerican Airlines
Wed 10/18:28 amGPT - PWM
2 stops10h 43mAmerican Airlines
Deal found 9/10$525
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2711:34 amPWM - GPT
2 stops22h 45mDelta
Wed 10/16:04 pmGPT - PWM
1 stop5h 07mDelta
Deal found 9/8$546

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.

Fly from

Portland

Fly to

Biloxi

Route

Depart

Return

Price

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 9/27

5:45 am-4:12 pm

2 stops11h 27m

Gulfport Biloxi Regional

Wed 10/1

7:00 am-11:13 pm

2 stops15h 13m

$522

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 9/27

5:10 pm-10:42 pm

1 stop6h 32m

Gulfport Biloxi Regional

Wed 10/1

8:28 am-8:11 pm

2 stops10h 43m

$525

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 9/27

11:34 am-9:19 am

2 stops22h 45m

Gulfport Biloxi Regional

Wed 10/1

6:04 pm-12:11 am

1 stop5h 07m

$546

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 10/22

1:27 pm-5:20 pm

1 stop4h 53m

$169

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 10/22

7:44 am-5:15 pm

2 stops10h 31m

$174

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Thu 9/25

12:18 pm-7:34 pm

1 stop8h 16m

$176

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Tue 9/30

1:40 pm-9:39 pm

2 stops8h 59m

$184

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 9/29

2:02 pm-10:42 pm

2 stops9h 40m

$194

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Thu 9/25

8:02 am-6:02 pm

2 stops11h 00m

$194

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Wed 10/22

11:16 am-8:59 am

3 stops46h 43m

$302

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 13 results
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Best time to book a flight from Portland to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi

What is the cheapest month to book a flight from Portland, Maine to Biloxi?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $256). Flying from Portland, Maine to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to B1L?

Find hourly flight availability from Portland to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Portland, Maine to Biloxi as you normally would.

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Portland to Biloxi. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    If you book a flight to Biloxi from Portland, you will be flying from Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland. There are 0 flights from Portland to Biloxi per day from 5 different airlines.

  • How long is the flight from Portland, Maine to Biloxi?

    There are many flights that can get you from Portland, Maine to Biloxi in 6h 32m. Fly via United Airlines, American Airlines, or Delta to get the fastest option. The distance from Portland, Maine to Biloxi is about 1374 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Portland, Maine to Biloxi one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $169. American Airlines flights start at $174 while deals on Sun Country Air start at $176 one-way.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Biloxi?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $256). Flying from Portland, Maine to Biloxi in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Portland to Biloxi

Discover the top 5 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$108Average$216FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$246Average$480FlexibilityNo cancel feeOn-time69%
DeltaCheapest$256Average$436FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$271Average$484FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$321Average$496FlexibilityNo cancel feeOn-time63%

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