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Biloxi

$184+ Cheap flights from Portland, ME (PWM) to Biloxi, MS

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — MSY
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Portland to Biloxi

Best flights from Portland to Biloxi
Discover carefully curated flight deals from Portland to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 4, 2025.

This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/248:40 amPWM - GPT
2 stops12h 08mUnited Airlines
Tue 1/274:42 pmGPT - PWM
2 stops20h 49mUnited Airlines
Deal found 12/2$533
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/97:00 amPWM - GPT
1 stop7h 19mAmerican Airlines
Mon 2/95:29 pmGPT - PWM
2 stops17h 37mAmerican Airlines
Deal found 12/3$856

Find flight deals from Portland to Biloxi

Keep the following information in mind while searching for Portland to Biloxi flight deals. Data was last updated December 4, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$533
(United Airlines)

One-way from

$184
(American Airlines)

Popular in

November

Cheapest in

January

Average price

$611
Provider with most accurate pricing for Portland-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Gulfport Biloxi Regional flights.
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From Portland to Biloxi
Search Deals
One-way flight from Portland to Biloxi
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($248 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($51 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Portland to Biloxi that are best for you.

Fly from

Portland

Fly to

Biloxi

Route

Depart

Return

Price

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Sat 1/24

8:40 am-7:48 pm

2 stops12h 08m

Gulfport Biloxi Regional

Tue 1/27

4:42 pm-2:31 pm

2 stops20h 49m

$533

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 2/9

7:00 am-1:19 pm

1 stop7h 19m

Gulfport Biloxi Regional

Mon 2/9

5:29 pm-12:06 pm

2 stops17h 37m

$856

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 2/9

12:40 pm-10:41 pm

2 stops11h 01m

$184

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Fri 12/19

6:00 am-4:08 pm

2 stops11h 08m

$329

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Fri 12/19

6:05 pm-7:15 pm

3 stops50h 10m

$336

PortlandGulfport

PWM - GPT

PWMGPT

Portland

Mon 2/9

3:12 pm-1:22 pm

3 stops47h 10m

$562

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Best time to book a flight from Portland to Biloxi

Have a flexible travel schedule? Discover the best time to fly to Biloxi from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Biloxi

What is the cheapest month to book a flight from Portland, Maine to Biloxi?

Currently, March is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $64). Flying from Portland, Maine to Biloxi in August is currently the most expensive (average of $123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to B1L?

Find hourly flight availability from Portland to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

It’s typically best to fly out from Portland, Maine to Biloxi in the evening. Doing so could potentially save you 56% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Biloxi

Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated December 4, 2025.
Read reviews from past customers who have flown American Airlines from Portland to Biloxi. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,047 reviews

Boarding

7.5

Crew

8.0

Food

6.5

Comfort

7.2

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,047 reviews
American Airlines
7.2
Good
11,047 reviews

Boarding

7.5

Crew

8.0

Food

6.5

Comfort

7.2

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Portland to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Biloxi?

    If you book a flight to Biloxi from Portland, you will be flying from Portland, which is the city’s only airport. Portland (PWM) is located 2.9 mi from the center of Portland. There are 0 flights from Portland to Biloxi per day from 5 different airlines.

  • How long is the flight from Portland, Maine to Biloxi?

    There are many flights that can get you from Portland, Maine to Biloxi in 7h 19m. Fly via United Airlines or American Airlines to get the fastest option. The distance from Portland, Maine to Biloxi is about 1374 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Portland to Biloxi that include hotel bookings?

    Yes. In addition to deals on Portland to Biloxi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Biloxi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Biloxi.

  • Can I find deals for business class flights from Portland to Biloxi?

    Yes. Cheapflights offers flight deals from Portland to Biloxi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Biloxi?

    Currently, March is the cheapest month in which you can book a flight from Portland, Maine to Biloxi (average of $64). Flying from Portland, Maine to Biloxi in August is currently the most expensive (average of $123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 5 airlines flying from Portland to Biloxi

Discover the top 5 airlines that operate flights from Portland to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$108Average$216FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$246Average$486FlexibilityNo cancel feeOn-time69%
DeltaCheapest$256Average$402FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$271Average$466FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$321Average$491FlexibilityNo cancel feeOn-time63%

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