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Panama City

$136+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/3. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JFK
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travelers. Please note that the information is based on the most recent updates available. Data last updated junio 12, 2025.

Cheapest one-way flight

$117

Cheapest round-trip flight

$58

Cheapest airline

Air Panama

Most popular destination

Bogotá El Dorado (BOG)

Good round-trip deal

$50 or less

Good one-way deal

$26 or less
The cheapest one-way flight from Panama City Tocumen Intl is currently to San José Juan Santamaria Intl.
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The cheapest round-trip flight from Panama City Tocumen Intl is currently to David Enrique Malek.
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On average, Air Panama currently has the cheapest one-way flight from Panama City Tocumen Intl (avg. price of $108).
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Bogotá El Dorado (BOG) is currently the most popular flight destination from Panama City Tocumen Intl (average round-trip price of $197).
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Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl.
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Find flights from Panama City

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on junio 12, 2025.

vie. 6/276:53 amPTY - MDE
Nonstop1h 24mCopa Airlines
mié. 7/29:42 amMDE - PTY
Nonstop1h 27mCopa Airlines
Deal found 6/11$207
lun. 6/161:30 pmPTY - MDE
1 stop24h 30mAvianca
mié. 6/181:25 pmMDE - PTY
Nonstop1h 15mAvianca
Deal found 6/12$224
sáb. 7/126:16 pmPTY - MIA
Nonstop3h 04mCopa Airlines
sáb. 7/195:23 pmMIA - PTY
Nonstop3h 06mCopa Airlines
Deal found 6/12$280
jue. 9/43:20 amPTY - MEX
1 stop15h 45mAvianca
mié. 9/2412:40 amMEX - PTY
1 stop14h 50mAvianca
Deal found 6/10$283
sáb. 7/53:20 amPTY - CUN
1 stop11h 20mAvianca
vie. 7/116:20 pmCUN - PTY
1 stop6h 25mAvianca
Deal found 6/11$283
vie. 6/273:20 pmPTY - MIA
Nonstop3h 05mAmerican Airlines
lun. 6/3010:30 amMIA - PTY
Nonstop3h 30mAmerican Airlines
Deal found 6/12$287
sáb. 6/287:55 amPTY - MIA
1 stop13h 44mUnited Airlines
mié. 7/27:00 amMIA - PTY
1 stop12h 37mUnited Airlines
Deal found 6/12$290
jue. 8/1411:43 amPTY - MEX
Nonstop3h 47mCopa Airlines
sáb. 8/302:00 amMEX - PTY
Nonstop3h 44mCopa Airlines
Deal found 6/12$292
lun. 9/17:11 amPTY - CUN
Nonstop2h 48mCopa Airlines
mié. 10/111:20 amCUN - PTY
Nonstop2h 41mCopa Airlines
Deal found 6/10$304
lun. 7/213:25 amPTY - MDE
1 stop5h 36mMultiple Airlines
mar. 7/297:38 amMDE - PTY
2 stops16h 32mMultiple Airlines
Deal found 6/11$312
lun. 6/165:25 pmPTY - MIA
1 stop15h 25mAvianca
vie. 6/207:20 pmMIA - PTY
1 stop6h 25mAvianca
Deal found 6/12$313
vie. 8/153:02 pmPTY - MEX
Nonstop3h 38mAeromexico
sáb. 8/238:40 amMEX - PTY
Nonstop3h 51mAeromexico
Deal found 6/10$324

Find flights from Panama City within your budget

Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on junio 12, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches

Fly to

John F Kennedy Intl

Route

Depart

Return

Price

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

vie. 6/27

6:53 am-8:17 am

Nonstop1h 24m

Medellín Jose Maria Cordova Intl

mié. 7/2

9:42 am-11:09 am

Nonstop1h 27m

$207

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

dom. 6/15

1:30 pm-2:00 pm

1 stop24h 30m

Medellín Jose Maria Cordova Intl

mar. 6/17

1:25 pm-2:40 pm

Nonstop1h 15m

$225

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

sáb. 7/12

6:16 pm-10:20 pm

Nonstop3h 04m

Miami

sáb. 7/19

5:23 pm-7:29 pm

Nonstop3h 06m

$280

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

jue. 9/4

3:20 am-6:05 pm

1 stop15h 45m

Mexico City Benito Juarez

mié. 9/24

12:40 am-4:30 pm

1 stop14h 50m

$283

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

sáb. 7/5

3:20 am-2:40 pm

1 stop11h 20m

Cancun

vie. 7/11

6:20 pm-12:45 am

1 stop6h 25m

$283

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

vie. 6/27

3:20 pm-7:25 pm

Nonstop3h 05m

Miami

lun. 6/30

10:30 am-1:00 pm

Nonstop3h 30m

$287

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

sáb. 6/28

7:55 am-10:39 pm

1 stop13h 44m

Miami

mié. 7/2

7:00 am-6:37 pm

1 stop12h 37m

$290

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

jue. 8/14

11:43 am-2:30 pm

Nonstop3h 47m

Mexico City Benito Juarez

sáb. 8/30

2:00 am-6:44 am

Nonstop3h 44m

$292

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

lun. 9/1

7:11 am-9:59 am

Nonstop2h 48m

Cancun

mié. 10/1

11:20 am-2:01 pm

Nonstop2h 41m

$304

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

lun. 7/21

3:25 am-9:01 am

1 stop5h 36m

Medellín Jose Maria Cordova Intl

mar. 7/29

7:38 am-12:10 am

2 stops16h 32m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 60 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to John F Kennedy Intl. Price data was last updated on June 9, 2025.

To ensure you get the cheapest price possible for a flight from Panama City, you should look to book at least 64 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Panama City?

Currently, January is the cheapest month in which you can book a flight from Panama City (average of $169). Flying from Panama City in July will prove the most costly (average of $435). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama City?

For flights departing from Panama City check dates and pricing for the following: Copa Airlines, Avianca, American Airlines. These airlines depart to the following popular destinations: New York.

Copa Airlines
Copa Airlines
From $61
Avianca
Avianca
From $157
United Airlines
United Airlines
From $194
Wingo
Wingo
From $37

What are popular destinations to fly to from Panama City?

Some of the most frequent flights departing from Panama City everyday are: Sao Paulo (250 flights per day), San José (149 flights per day), and Miami (120 flights per day).

Bogotá El Dorado
Bogotá El Dorado
From $68
Miami
Miami
From $215
Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From $68
Houston Hobby
Houston Hobby
From $271

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is David Enrique Malek, with prices starting at $25. Explore other affordable destinations below.

David Enrique Malek
David Enrique Malek
From $25
Bogotá El Dorado
Bogotá El Dorado
From $68
Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From $68
Barranquilla E Cortissoz
Barranquilla E Cortissoz
From $70

Airline reviews for flights from Panama City

Read reviews and ratings of airlines operating flights from Panama City. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Panama City travel. Please note that the reviews are sourced from user searches and were last updated on junio 12, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches.
Copa Airlines
7.5
Good
1,451 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.5

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Copa Airlines
7.5
Good
1,451 reviews
Copa Airlines
7.5
Good
1,451 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.5

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Avianca
6.7
Okay
2,345 reviews
Copa Airlines
7.5
Good
1,451 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Overall

7.5

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Browse thousands of different options on Cheapflights for your next trip

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Popular international destinations from Panama City

The most popular international flight routes departing from Panama City we’ve come across at this time.
Flights from Panama City to Bogotá
Flights from Panama City to Miami
Flights from Panama City to Madrid
Flights from Panama City to Atlanta
Flights from Panama City to San Salvador
Flights from Panama City to Amsterdam
Flights from Panama City to San José
Flights from Panama City to Tampa
Flights from Panama City to Guatemala City
Flights from Panama City to San Francisco
Flights from Panama City to Los Angeles
Flights from Panama City to Cartagena
Flights from Panama City to Cancún
Flights from Panama City to Mexico City
Flights from Panama City to Managua
Flights from Panama City to Lima
Flights from Panama City to Santo Domingo
Flights from Panama City to Punta Cana

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated junio 12, 2025.

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Cancún, Cali. Throughout the year, Bogotá, Cancún, Cartagena are some of the top choices made by users flying from Panama City.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as $58 to David (prices may vary depending on the airline and departure time). On average, users have booked flights for $665 to fly from Panama City.

  • What are the cheapest airlines flying from Panama City to anywhere?

    Over the past few days, we've found that Webjet Linhas Aereas, Wingo, and Copa Airlines have the cheapest prices from Panama City. Webjet Linhas Aereas flights from Panama City to David Enrique Malek ($36), Wingo flights from Panama City to Barranquilla E Cortissoz ($37), and Copa Airlines flights from Panama City to San Andres Island ($61).

  • What is the cheapest premium economy flight from Panama City?

    Options for some of the cheapest premium economy flights from Panama City we have found on Cheapflights are as follows:
    Fly from Panama City Tocumen Intl to Bogotá starting at $714
    Fly from Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl Airport starting at $816
    Fly from Panama City Tocumen Intl to Mexico City starting at $832
    Fly from Panama City Tocumen Intl to George Town starting at $868

  • What is the cheapest first class flight from Panama City?

    If you’re looking for a cheap first-class flight from Panama City, consider Houston. Prices start at $1,935 so you can fly first-class even on a budget.

  • What is the cheapest month to fly from Panama City?

    January is currently the cheapest month to fly from Panama City. At this moment in time July is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • Where are the cheapest places to fly to from Panama City?

    Check out the cheapest flights from Panama City to embark to:
    Fly from Panama City to Medellín from $139 round trip
    Fly from Panama City to Bogotá from $147 round trip
    Fly from Panama City to San Salvador from $186 round trip
    Fly from Panama City to San José from $188 round trip
    Fly from Panama City to Guatemala City from $202 round trip

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