Cheap Car Rentals in Otay Mesa, San Diego from $25
This price is the cheapest per day rate found by a Cheapflights user in the last 48 hours by searching for a car rental in Otay Mesa with a pick-up date of 9/19 and drop-off date of 9/20. Fares are subject to change and may not be available at all agencies or on all dates of rental.
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Otay Mesa, San Diego car rentals in 2026
Get helpful information to start your search for the perfect car rental in Otay Mesa. The average price data is based on the last 12 months and was last updated on September 13, 2026.
Most popular company | Budget |
|---|---|
Most common car type | Intermediate |
Average price per day | $52 |
Cheapest price per day | $25 |
Best Otay Mesa, San Diego car rental deals
Browse through the best deals we’ve found on Otay Mesa car rental deals at this time. Deals are sourced from providers and were last updated on September 13, 2026.
BMW X1$36/day
Cadillac ATS$58/day
Ford Focus Sedan$27/day
Cheapflights insights for Otay Mesa car rentals
Get relevant, data-driven information to help you rent a car in Otay Mesa, including pricing trends, ideal booking times, and more.
How far in advance should I rent a car in Otay Mesa?
Book your rental car in Otay Mesa 7 days before your pickup date to maximize your savings Car rental prices are around $30/day on average when booked 7 days ahead, which saves you 10% off the usual average price.
What is the best car rental company in Otay Mesa?
Based on Cheapflights user feedback, the highest rated car rental company in Otay Mesa is Hertz (rated 5.5/10 with 158 reviews). Sixt (rated 7.5/10) is also highly rated by our users.
Hertz
5.5
Sixt
7.5
Budget
6.4
Avis
6.3
What is the cheapest month to rent a car in Otay Mesa?
Planning a car rental in Otay Mesa? January is the cheapest month, costing about $28 per day. In contrast, May is the most expensive, with an average daily rate of $38. Monthly average rental prices are listed below. Remember, prices can change based on when you book, the type of car, and availability.
January
$28
February
$28
March
$34
April
$35
May
$38
June
$37
July
$36
August
$35
September
$28
October
$37
November
$34
December
$29
Top rental agencies in Otay Mesa, San Diego
Explore the most popular car rental suppliers in Otay Mesa, including their locations and customer reviews, to make the best choice for your next trip.
Overview
Reviews
Locations
Hertz
158 reviews•2 locations
Overview
Cleanliness
6.5
Comfort
6.3
Overall
5.5
Pick-up/drop-off
5.6
Value
5.8
Recent reviews
10.0
|Sep 2023Your customer service person who helped me with correcting my rental was awesome.
10.0
|Aug 2023When we arrived at San Diego Airport, we were told that our reservation was Tijuana not San Diego. I had a print out of my reservation and it showed Pick-up and Return were both San Diego. I ended up paying $90 more than my reserved price. I was not very happy about it.
2.0
|Jul 2023Location was not san Diego Airport. I That's what we asked for and the reservation was for Otay. Had to redo everything at .much higher lrice. Will never use kayak again
10.0
|Jul 2023We had an issue with where our original rental was planned and the gentleman at San Diego airport did a great job in fixing our situation
10.0
|Jul 2023I found it very easy to cancel a reservation. As they say " ... with no questions asked ..." excellent customer service.
2.0
|Jul 2023The kayak app put the car rental at the wrong airport. I put thaw San Diego airport and the kayak App switched it to the Tijuana airport without notifying me. I had to Uber to the other airport which cost over $50 and pay to change the drop off to the San Diego airport which cost another $90. I will not use the kayak app ever again.
1 out of 53
View Hertz Locations in Otay Mesa
Overview
Locations
Sixt
1 location
Overview
Cleanliness
8.0
Comfort
8.1
Overall
7.5
Pick-up/drop-off
7.7
Value
7.3
View Sixt Locations in Otay Mesa
Overview
Locations
Budget
11 reviews•1 location
Overview
Cleanliness
7.3
Comfort
7.3
Overall
6.4
Pick-up/drop-off
6.5
Value
6.5
View Budget Locations in Otay Mesa
Overview
Reviews
Locations
Avis
29 reviews•1 location
Overview
Cleanliness
7.2
Comfort
7.3
Overall
6.3
Pick-up/drop-off
6.6
Value
6.5
Recent reviews
10.0
|Apr 2023Easy peasy, great desk staff too!
2.0
|Mar 2023Worst experience I’ve had renting a car. Lady at desk was rude and wouldn’t help me out.
1 out of 10
View Avis Locations in Otay Mesa
Overview
Locations
Thrifty
1 location
Overview
Cleanliness
6.7
Comfort
6.2
Overall
5.7
Pick-up/drop-off
5.9
Value
5.8
View Thrifty Locations in Otay Mesa
Overview
Reviews
Locations
Dollar
19 reviews•1 location
Overview
Cleanliness
6.6
Comfort
6.3
Overall
5.4
Pick-up/drop-off
5.7
Value
5.7
Recent reviews
2.0
|Feb 2025It totally sucked. I checked ahead just to make sure that they rented if you only had a debit card. Their website assured that if you had two forms of ID iall rentals was approved. Well that was a total LIE. I drove all the way to the Mexico border ( CBX ) just for them to say...."We don't accept debt card only credit card for our rentals. That's our policy". I ended up be late for my 100 year old granddaughters funeral on the account that I had to find other options to travel to Flagstaff AZ.....all because I trusted in what their website stated. So how was my experience?....it sucked BIG TIME!
1 out of 7
View Dollar Locations in Otay Mesa
Overview
Locations
Ace
7 reviews•1 location
Overview
Cleanliness
5.1
Comfort
5.0
Overall
4.4
Pick-up/drop-off
4.2
Value
4.7
View Ace Locations in Otay Mesa
Overview
Reviews
Locations
MEXRENTACAR
15 reviews•1 location
Overview
Cleanliness
4.4
Comfort
4.3
Overall
3.7
Pick-up/drop-off
3.7
Value
4.0
Recent reviews
2.0
|Nov 2022Car was at Mexican border not in San Diego as advertised
2.0
|Nov 2022Never got the car ..called back to cancel reservation ..none of the phone numbers worked all said out of service ..unable to complete call ..not a working number ..and some Spanish message …I put in the San Diego airport and your system was sending me to who knows where in San Diego ..wasn’t the airport
2.0
|Mar 2022I had a reservation but they didn’t have any car form me, and I didn’t get a refund. It’s a scam
1 out of 5
View MEXRENTACAR Locations in Otay Mesa
Otay Mesa Car rental FAQs
Find answers to frequently asked questions about car rentals in Otay Mesa, including policies, requirements, and more. FAQs were last updated on September 13, 2026.
Can I rent a car for a month at Otay Mesa?
Yes, renting a vehicle at Otay Mesa for a month is certainly possible.
What is the cheapest rental car in Otay Mesa, San Diego?
The cheapest rental car in Otay Mesa, San Diego is Kia Soul. It costs $28 per day on average to rent a Kia Soul in this area of the city, which is 44% cheaper than other rental cars in the neighborhood.
How much is a rental car in Otay Mesa, San Diego?
In Otay Mesa, San Diego, rental cars cost $28/day on average, and as low as $29 per day. Keep in mind that prices may vary depending on when you book and what type of rental car you choose.
Car rentals by fuel type in Otay Mesa
Browse car rentals by fuel type in Otay Mesa. Currently, Electric cars are the cheapest to rent in Otay Mesa. Deals were last updated on September 13, 2026.
Browse through car rental deals by fuel type in Otay Mesa. There are currently 2 fuel types to choose from with Electric being the cheapest ($31+).
Electric
$31+
Hybrid
$39+
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