Tuscany

$360+ Cheap flights from Des Moines (DSM) to Tuscany

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — FLR
Jan 3 — Jan 101
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Cheap flight deals from Des Moines to Tuscany

Cheapest flights from Des Moines to Tuscany
Explore the most affordable flight options available from Des Moines to Tuscany. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/911:35 amDSM - FCO
1 stop13h 10mLufthansa
Tue 12/167:05 amFCO - DSM
2 stops17h 19mLufthansa
Deal found 12/2$431
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:34 amDSM - FCO
2 stops21h 11mDelta
Tue 12/169:20 amFCO - DSM
2 stops20h 14mDelta
Deal found 12/2$461
This Expedia deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:50 amDSM - FCO
2 stops22h 05mIberia
Mon 12/228:20 pmFCO - DSM
2 stops34h 10mIberia
Deal found 12/3$617
This oojo deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:40 amDSM - FCO
2 stops21h 00mMultiple Airlines
Tue 1/138:25 pmFCO - DSM
2 stops31h 39mMultiple Airlines
Deal found 12/1$695
This KLM deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:30 pmDSM - FCO
1 stop33h 00mKLM
Tue 1/136:10 amFCO - DSM
2 stops16h 31mKLM
Deal found 12/1$777
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 pmDSM - FLR
2 stops34h 49mUnited Airlines
Thu 1/19:45 amFLR - DSM
2 stops39h 20mUnited Airlines
Deal found 12/4$1,048
This Air Canada deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:00 amDSM - FCO
3 stops21h 40mMultiple Airlines
Tue 12/161:10 pmFCO - DSM
2 stops28h 43mMultiple Airlines
Deal found 12/2$1,084
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/168:00 amDSM - FCO
1 stop16h 45mUnited Airlines
Mon 12/2210:30 amFCO - DSM
2 stops18h 10mUnited Airlines
Deal found 12/2$1,113
This Ovago deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:40 amDSM - FCO
2 stops22h 00mAer Lingus
Mon 12/2211:20 amFCO - DSM
2 stops43h 10mAer Lingus
Deal found 12/2$1,128
This FlightHub deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:00 amDSM - FCO
3 stops21h 40mAir Canada
Tue 12/167:05 amFCO - DSM
3 stops21h 45mAir Canada
Deal found 12/2$1,174
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1512:15 pmDSM - FCO
2 stops18h 40mAmerican Airlines
Mon 12/221:10 pmFCO - DSM
1 stop17h 25mAmerican Airlines
Deal found 12/3$1,201
This FlightHub deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 pmDSM - FLR
2 stops34h 49mLufthansa
Thu 1/15:15 pmFLR - DSM
2 stops35h 25mLufthansa
Deal found 12/4$2,274

Find flight deals from Des Moines to Tuscany

Keep the following information in mind while searching for Des Moines to Tuscany flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$438
(oojo)

One-way from

$360
(Kiwi.com)

Popular in

June

Cheapest in

October

Average price

$1,472
Provider with most accurate pricing for Des Moines-Florence Peretola flight deals.
Provider most trusted by Cheapflights users for Des Moines-Florence Peretola flights.
From Des Moines to Tuscany
One-way flight from Des Moines to Tuscany
Highest demand for flights based on searches. 15% potential increase in price ($234 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($43 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Tuscany that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Des Moines to Tuscany that are best for you.

Fly from

Des Moines

Fly to

Tuscany

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 2/11

11:42 am-11:45 am

2 stops41h 03m

Florence Peretola

Wed 2/18

12:10 pm-10:26 pm

2 stops17h 16m

$438

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 3/17

11:17 am-5:55 pm

2 stops24h 38m

Rome Fiumicino

Tue 3/24

6:40 pm-11:42 pm

2 stops35h 02m

$463

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 3/17

11:17 am-5:55 pm

2 stops24h 38m

Rome Fiumicino

Tue 3/24

6:40 pm-11:42 pm

2 stops35h 02m

$463

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sun 1/18

6:48 pm-4:30 pm

2 stops14h 42m

Florence Peretola

Sun 1/25

6:30 am-9:50 pm

2 stops22h 20m

$465

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Fri 1/16

11:42 am-11:45 am

2 stops41h 03m

Florence Peretola

Fri 1/23

12:45 pm-4:24 pm

2 stops34h 39m

$468

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sat 1/17

3:35 pm-12:35 pm

2 stops14h 00m

Florence Peretola

Sat 1/24

6:30 am-9:50 pm

2 stops22h 20m

$468

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 1/14

11:26 am-3:15 pm

2 stops20h 49m

Rome Fiumicino

Wed 1/21

12:40 pm-10:29 pm

1 stop16h 49m

$475

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sun 1/18

6:48 pm-10:00 pm

2 stops20h 12m

Florence Peretola

Sun 1/25

6:30 am-9:50 pm

2 stops22h 20m

$479

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 1/14

3:35 pm-1:25 pm

2 stops14h 50m

Rome Fiumicino

Wed 1/21

7:05 am-9:50 pm

2 stops21h 45m

$483

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sat 1/17

12:25 pm-11:20 am

2 stops15h 55m

Florence Peretola

Sat 1/24

6:40 am-5:08 pm

2 stops17h 28m

$489

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 27 results
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Best time to book a flight from Des Moines to Tuscany

Have a flexible travel schedule? Discover the best time to fly to Tuscany from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Tuscany
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Tuscany

Get insights into the airlines that provide service to Tuscany. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Tuscany. Reviews last updated December 4, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and Lufthansa from Des Moines to Tuscany by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Tuscany. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Des Moines to Tuscany?

    For a flight from Des Moines to Tuscany, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Tuscany?

    A quick flight from Des Moines to Tuscany can take about 20h 49m. British Airways provides one of the quickest options available for as low as $475. The distance between Des Moines and Tuscany is about 5054 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Des Moines to Tuscany that include hotel bookings?

    Yes. In addition to deals on Des Moines to Tuscany flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Tuscany?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Tuscany.

  • Can I find deals for business class flights from Des Moines to Tuscany?

    Yes. Cheapflights offers flight deals from Des Moines to Tuscany by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 3 airlines flying from Des Moines to Tuscany

Discover the top 3 airlines that operate flights from Des Moines to Tuscany. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$738Average$1,366FlexibilityNo cancel feeOn-time76%
United AirlinesCheapest$790Average$1,308FlexibilityNo cancel feeOn-time69%
DeltaCheapest$923Average$1,519FlexibilityNo cancel feeOn-timeN/A

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