In terms of precipitation, rainfall in Tupelo ranges from 3.5 - 6.4 inches per month. December is typically the wettest month, when rainfall can reach 6.4 in. September is typically the driest time to visit Tupelo when rainfall is around 3.5 in.

If weather is an important factor for your trip to Tupelo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What is the cheapest time of day to fly from TYS to TUP?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Tupelo as you normally would.

Most accurate provider : When it comes to deals on Knoxville-Tupelo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Tupelo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Tupelo flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Knoxville-Tupelo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Tupelo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Knoxville to Tupelo that include hotel bookings?

Yes. In addition to deals on Knoxville to Tupelo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Tupelo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Tupelo.

Can I find deals for business class flights from Knoxville to Tupelo?

Yes. Cheapflights offers flight deals from Knoxville to Tupelo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$236+ Cheap Flights from Knoxville to Tupelo

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One-way flights from Knoxville to Tupelo
Search for one-way flight options from Knoxville to Tupelo. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.

Thu 10/11:37 pm -

3 stops47h 33m

Wed 12/3112:00 am -

Nonstop0h 00m

Deal found 9/9

$236

Wed 9/3010:28 am -

2 stops26h 42m

Wed 12/3112:00 am -

Nonstop0h 00m

Deal found 9/10

$238

Find flight deals from Knoxville to Tupelo

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars

Provider with most accurate pricing for Knoxville McGhee Tyson-Tupelo Lemons Municipal flight deals.

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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Tupelo Lemons Municipal flights.

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KnoxvilleTupelo

TYS Knoxville McGhee Tyson - TUP Tupelo Lemons Municipal

TYSTUP

Knoxville McGhee Tyson

Wed 9/30

10:28 am-12:10 pm

2 stops26h 42m

Tupelo Lemons Municipal

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$238

KnoxvilleTupelo

TYS Knoxville McGhee Tyson - TUP Tupelo Lemons Municipal

TYSTUP

Knoxville McGhee Tyson

Thu 10/1

6:15 am-12:10 pm

2 stops30h 55m

Tupelo Lemons Municipal

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$261

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Sorted by cheapest first

Most accurate provider: When it comes to deals on Knoxville-Tupelo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Tupelo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Tupelo flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Knoxville-Tupelo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Tupelo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Tupelo

Have a flexible travel schedule? Discover the best time to fly to Tupelo from Knoxville with our price prediction graph.

TYS-TUP

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Can I find deals for flights from Knoxville to Tupelo that include hotel bookings?
Yes. In addition to deals on Knoxville to Tupelo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Tupelo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Tupelo.
Can I find deals for business class flights from Knoxville to Tupelo?
Yes. Cheapflights offers flight deals from Knoxville to Tupelo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Tupelo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to Tupelo

One-way flights from Knoxville to Tupelo
Search for one-way flight options from Knoxville to Tupelo. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.

Search for one-way flight options from Knoxville to Tupelo. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.

Find flight deals from Knoxville to Tupelo

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Use the filters below to find and compare flights from Knoxville to Tupelo that are best for you.

Best time to book a flight from Knoxville to Tupelo

Have a flexible travel schedule? Discover the best time to fly to Tupelo from Knoxville with our price prediction graph.

Related info for your journey

Can I find deals for flights from Knoxville to Tupelo that include hotel bookings?

How can I find direct flights from Knoxville to Tupelo?

Can I find deals for business class flights from Knoxville to Tupelo?

Traveling to a place near Tupelo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Tupelo

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Complete your trip

Complete your trip to Tupelo by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Knoxville to Tupelo by cabin class

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Knoxville and Tupelo flights

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$236+ Cheap flights from Knoxville to Tupelo (TYS - TUP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Tupelo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to Tupelo

One-way flights from Knoxville to TupeloSearch for one-way flight options from Knoxville to Tupelo. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.

Search for one-way flight options from Knoxville to Tupelo. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.

Find flight deals from Knoxville to Tupelo

Most accurate provider

Most trusted provider

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Tupelo that are best for you.

Best time to book a flight from Knoxville to Tupelo

Have a flexible travel schedule? Discover the best time to fly to Tupelo from Knoxville with our price prediction graph.

Related info for your journey

Can I find deals for flights from Knoxville to Tupelo that include hotel bookings?

How can I find direct flights from Knoxville to Tupelo?

Can I find deals for business class flights from Knoxville to Tupelo?

Traveling to a place near Tupelo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Tupelo

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Tupelo by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Knoxville to Tupelo by cabin class

Find flights from Knoxville to Tupelo, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Knoxville and Tupelo flights

Browse other Knoxville and Tupelo flight options. Last updated on September 13, 2026.

Other flights from Knoxville

Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 13, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

Other flights to Tupelo

Explore flights to Tupelo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 13, 2026.

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Travel Smart

One-way flights from Knoxville to Tupelo
Search for one-way flight options from Knoxville to Tupelo. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.