HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Syracuse

$136+ Cheap flights from Myrtle Beach to Syracuse (MYR - SYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SYR
Jan 8 — Jan 151
Thu 1/8
Thu 1/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Myrtle Beach to Syracuse with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Myrtle Beach to Syracuse

Cheapest flights from Myrtle Beach to Syracuse
Explore the most affordable flight options available from Myrtle Beach to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 9, 2025.

This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:08 pmMYR - SYR
1 stop6h 22mAmerican Airlines
Sat 12/135:31 pmSYR - MYR
2 stops6h 23mAmerican Airlines
Deal found 12/7$404
This Delta deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:56 pmMYR - SYR
1 stop4h 37mDelta
Tue 12/307:00 amSYR - MYR
1 stop4h 15mDelta
Deal found 12/8$414
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:37 pmMYR - SYR
1 stop4h 22mAmerican Airlines
Sun 12/2112:17 pmSYR - MYR
1 stop5h 59mAmerican Airlines
Deal found 12/9$469
This Kiwi.com deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:54 amMYR - SYR
1 stop24h 51mMultiple Airlines
Fri 12/268:12 pmSYR - MYR
2 stops21h 56mMultiple Airlines
Deal found 12/6$559
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:54 amMYR - SYR
1 stop24h 51mMultiple Airlines
Sat 12/278:12 pmSYR - MYR
1 stop22h 25mMultiple Airlines
Deal found 12/7$581
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:30 amMYR - SYR
2 stops7h 29mAmerican Airlines
Tue 12/305:29 pmSYR - MYR
2 stops6h 26mAmerican Airlines
Deal found 12/8$619

Find flight deals from Myrtle Beach to Syracuse

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Syracuse (SYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 9, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$250
(Kiwi.com)

One-way from

$136
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$358
Provider with most accurate pricing for Myrtle Beach Intl-Syracuse Hancock Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Syracuse Hancock Intl flights.
Search Deals
From Myrtle Beach Intl to Syracuse Hancock Intl
Search Deals
One-way flight from Myrtle Beach Intl to Syracuse Hancock Intl
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($63 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Syracuse that are best for you.

Fly from

Myrtle Beach

Fly to

Syracuse

Route

Depart

Return

Price

Myrtle BeachSyracuse

MYR - SYR

MYRSYR

Myrtle Beach Intl

Wed 3/4

3:59 pm-4:22 pm

3 stops24h 23m

Syracuse Hancock Intl

Sun 3/8

4:03 pm-6:13 pm

Nonstop2h 10m

$329

Myrtle BeachSyracuse

MYR - SYR

MYRSYR

Myrtle Beach Intl

Thu 1/8

4:00 pm-12:22 am

2 stops8h 22m

Syracuse Hancock Intl

Mon 1/12

12:41 pm-11:43 pm

2 stops11h 02m

$333

Myrtle BeachSyracuse

MYR - SYR

MYRSYR

Myrtle Beach Intl

Fri 2/20

2:21 pm-11:09 pm

2 stops8h 48m

Syracuse Hancock Intl

Fri 2/27

6:05 am-11:35 am

1 stop5h 30m

$356

Myrtle BeachSyracuse

MYR - SYR

MYRSYR

Myrtle Beach Intl

Thu 1/1

6:43 pm-10:58 pm

1 stop4h 15m

Syracuse Hancock Intl

Sun 1/4

6:26 pm-11:55 pm

1 stop5h 29m

$387

Myrtle BeachSyracuse

MYR - SYR

MYRSYR

Myrtle Beach Intl

Thu 1/1

11:27 am-4:33 pm

1 stop5h 06m

Syracuse Hancock Intl

Mon 1/5

6:15 am-11:42 am

1 stop5h 27m

$387

Myrtle BeachSyracuse

MYR - SYR

MYRSYR

Myrtle Beach Intl

Thu 1/1

6:00 am-11:45 am

2 stops5h 45m

Syracuse Hancock Intl

Mon 1/5

3:36 pm-11:55 pm

2 stops8h 19m

$397

Myrtle BeachSyracuse

MYR - SYR

MYRSYR

Myrtle Beach Intl

Fri 2/20

2:21 pm-11:09 pm

2 stops8h 48m

Syracuse Hancock Intl

Sat 2/28

12:45 pm-11:57 pm

2 stops11h 12m

$397

Myrtle BeachSyracuse

MYR - SYR

MYRSYR

Myrtle Beach Intl

Fri 2/20

6:00 am-1:06 pm

1 stop7h 06m

Syracuse Hancock Intl

Sat 2/28

5:18 pm-10:57 pm

2 stops5h 39m

$404

Myrtle BeachSyracuse

MYR - SYR

MYRSYR

Myrtle Beach Intl

Wed 12/17

2:40 pm-11:11 pm

2 stops8h 31m

Syracuse Hancock Intl

Tue 12/30

7:00 am-11:15 am

1 stop4h 15m

$419

Myrtle BeachSyracuse

MYR - SYR

MYRSYR

Myrtle Beach Intl

Thu 1/15

5:53 pm-11:22 am

2 stops17h 29m

$136

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Showing 1-10 of 14 results
1
2

Compare providers for flights from Myrtle Beach to Syracuse

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Syracuse in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Syracuse flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-Syracuse flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Syracuse flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Syracuse flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Syracuse

What is the cheapest month to book a flight from Myrtle Beach to Syracuse?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Syracuse (average of $46). Flying from Myrtle Beach to Syracuse in February is currently the most expensive (average of $136). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SYR?

Find hourly flight availability from Myrtle Beach to Syracuse. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 9, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 66% on flights from Myrtle Beach to Syracuse by exploring options for tickets in the afternoon.

Reviews of airlines servicing Syracuse

Get insights into the airlines that provide service to Syracuse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Syracuse. Reviews last updated December 9, 2025.
Read reviews from past customers who have flown Delta, American Airlines, and Allegiant Air from Myrtle Beach to Syracuse. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
American Airlines
7.2
Good
11,043 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
Allegiant Air
7.2
Good
698 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Syracuse?

    Departing from Myrtle Beach to Syracuse will take you 4h 15m. The distance between Myrtle Beach and Syracuse is about 669 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Myrtle Beach to Syracuse round-trip?

    Our cheapest airline available from Myrtle Beach to Syracuse is Allegiant Air. Our recent data shows that you can find tickets from as low as $81 on this airline. Additional options worth looking into are Delta and American Airlines, starting at $161 and $210 round-trip. Allegiant Air is priced at 70% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Myrtle Beach to Syracuse one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $53. Delta flights start at $105 while deals on American Airlines start at $137 one-way.

  • Can I find deals for flights from Myrtle Beach to Syracuse that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Syracuse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Syracuse.

  • Can I find deals for business class flights from Myrtle Beach to Syracuse?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Syracuse?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Syracuse (average of $46). Flying from Myrtle Beach to Syracuse in February is currently the most expensive (average of $136). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
Liverpool
East Syracuse
Waterloo

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to Syracuse

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Charlotte to Newark flights
Charlotte to LaGuardia flights
Charleston to John F Kennedy Intl flights
Greenville to LaGuardia flights
Charleston to LaGuardia flights
Greenville to Newark flights
Charleston to Newark flights
Savannah to LaGuardia flights
Savannah to John F Kennedy Intl flights
Greenville to John F Kennedy Intl flights
Savannah to Newark flights
Columbia to LaGuardia flights
Myrtle Beach to Newark flights
Columbia to John F Kennedy Intl flights
Myrtle Beach to John F Kennedy Intl flights
Myrtle Beach to LaGuardia flights
Charlotte to Islip flights
Charlotte to Stewart flights
Charleston to White Plains flights
Columbia to Newark flights
Charlotte to Buffalo flights
Augusta to John F Kennedy Intl flights
Myrtle Beach to White Plains flights
Augusta to LaGuardia flights
Charlotte to Albany flights
Charleston to Stewart flights
Charlotte to Syracuse flights
Augusta to Newark flights
Charleston to Islip flights
Charlotte to White Plains flights
Charlotte to Rochester flights
Myrtle Beach to Stewart flights
Charleston to Buffalo flights
Greenville to Stewart flights
Columbia to White Plains flights
Savannah to Buffalo flights
Savannah to White Plains flights
Greenville to Buffalo flights
Myrtle Beach to Islip flights
Greenville to White Plains flights
Charleston to Albany flights
Greenville to Rochester flights
Myrtle Beach to Buffalo flights
Savannah to Syracuse flights
Savannah to Albany flights
Savannah to Stewart flights
Columbia to Syracuse flights
Columbia to Albany flights

Top 3 airlines flying from Myrtle Beach to Syracuse

Discover the top 3 airlines that operate flights from Myrtle Beach to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$96Average$173FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$210Average$336FlexibilityNo cancel feeOn-time71%
DeltaCheapest$210Average$283FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.