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$86+ Cheap flights from Syracuse to St. Louis (SYR - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — STL
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Syracuse to St. Louis

Cheapest flights from Syracuse to St. Louis
Explore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/145:50 am
SYR
-
STL
1 stop4h 56m
Delta
Tue 3/175:21 pm
STL
-
SYR
1 stop5h 38m
Delta
Deal found 1/26$251
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:27 pm
SYR
-
STL
1 stop4h 38m
United Airlines
Sat 2/287:00 am
STL
-
SYR
1 stop4h 20m
United Airlines
Deal found 1/25$260
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:27 pm
SYR
-
STL
1 stop5h 13m
United Airlines
Sat 2/289:55 am
STL
-
SYR
2 stops9h 19m
United Airlines
Deal found 1/27$265
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:17 am
SYR
-
STL
1 stop5h 46m
American Airlines
Sun 3/16:00 am
STL
-
SYR
1 stop4h 13m
American Airlines
Deal found 1/26$269
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:30 am
SYR
-
STL
1 stop5h 40m
Delta
Sat 11/73:42 pm
STL
-
SYR
1 stop7h 13m
Delta
Deal found 1/26$271
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/712:41 pm
SYR
-
STL
1 stop4h 56m
Delta
Tue 2/105:56 pm
STL
-
SYR
1 stop4h 17m
Delta
Deal found 1/25$279
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:18 am
SYR
-
STL
1 stop6h 36m
Delta
Mon 7/203:42 pm
STL
-
SYR
1 stop7h 16m
Delta
Deal found 1/25$280
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/108:00 am
SYR
-
STL
1 stop7h 30m
United Airlines
Sat 2/1411:25 am
STL
-
SYR
2 stops7h 49m
United Airlines
Deal found 1/26$284
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/102:15 pm
SYR
-
STL
2 stops7h 17m
American Airlines
Sat 2/146:13 am
STL
-
SYR
2 stops8h 22m
American Airlines
Deal found 1/26$290
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/145:50 am
SYR
-
STL
1 stop4h 56m
Delta
Mon 3/236:32 am
STL
-
SYR
1 stop4h 02m
Delta
Deal found 1/26$305
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/55:18 pm
SYR
-
STL
1 stop5h 33m
American Airlines
Mon 2/96:44 pm
STL
-
SYR
1 stop4h 10m
American Airlines
Deal found 1/26$309

Find flight deals from Syracuse to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$251
(Delta)

One-way from

$86
(Priceline)

Popular in

March

Cheapest in

February

Average price

$319
Provider with most accurate pricing for Syracuse Hancock Intl-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Lambert-St Louis flights.
Search Deals
From Syracuse Hancock Intl to Lambert-St Louis
Search Deals
One-way flight from Syracuse Hancock Intl to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Syracuse to St. Louis that are best for you.

Fly from

Syracuse

Fly to

St. Louis

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 2/21

5:50 am-9:32 am

1 stop4h 42m

Lambert-St Louis

Sat 2/28

5:50 pm-11:13 pm

1 stop4h 23m

$260

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 2/21

5:27 pm-9:05 pm

1 stop4h 38m

Lambert-St Louis

Sat 2/28

7:00 am-12:20 pm

1 stop4h 20m

$260

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 5/28

6:18 am-11:54 am

1 stop6h 36m

Lambert-St Louis

Tue 6/2

5:45 pm-10:56 pm

1 stop4h 11m

$260

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 2/25

5:27 pm-9:40 pm

1 stop5h 13m

Lambert-St Louis

Sat 2/28

7:00 am-12:20 pm

1 stop4h 20m

$260

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 2/7

12:41 pm-4:37 pm

1 stop4h 56m

Lambert-St Louis

Tue 2/10

5:56 pm-11:13 pm

1 stop4h 17m

$279

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 2/10

12:41 pm-4:37 pm

1 stop4h 56m

Lambert-St Louis

Sat 2/14

5:50 pm-11:13 pm

1 stop4h 23m

$279

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 7/16

6:18 am-11:54 am

1 stop6h 36m

Lambert-St Louis

Sun 7/19

5:00 pm-11:57 pm

1 stop5h 57m

$280

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 2/10

8:00 am-2:30 pm

1 stop7h 30m

Lambert-St Louis

Sat 2/14

11:25 am-8:14 pm

2 stops7h 49m

$284

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Tue 2/10

2:15 pm-8:32 pm

2 stops7h 17m

Lambert-St Louis

Sat 2/14

6:13 am-3:35 pm

2 stops8h 22m

$290

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Sat 5/16

12:50 pm-11:19 pm

1 stop11h 29m

$86

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 17 results
1
2

Compare providers for flights from Syracuse to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to St. Louis in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to St. Louis

How far ahead should I book a flight from Syracuse to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to St. Louis. Price data was last updated on January 23, 2026.

To ensure you get the cheapest price possible for a flight from Syracuse to St. Louis, you should look to book at least 24 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Syracuse to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Syracuse to St. Louis (average of $203). Flying from Syracuse to St. Louis in May is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated January 27, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Syracuse to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,119 reviews

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,119 reviews
Delta
7.9
Good
8,119 reviews

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,205 reviews
Delta
7.9
Good
8,119 reviews

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,119 reviews

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to St. Louis?

    Airlines like Delta and United Airlines fly from Syracuse to St. Louis in about 4h 38m. The time it takes to get you to your destination can typically vary by up to 04m. Airlines will cover a distance of 801 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Syracuse to St. Louis round-trip?

    According to our current data, American Airlines ($248), United Airlines ($248), and Delta ($248) offers the cheapest pricing from Syracuse to St. Louis. American Airlines is 29% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Syracuse to St. Louis one-way?

    $118 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on United Airlines and American Airlines, with prices starting from $142 and $175, respectively.

  • Can I find deals for flights from Syracuse to St. Louis that include hotel bookings?

    Yes. In addition to deals on Syracuse to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to St. Louis.

  • Can I find deals for business class flights from Syracuse to St. Louis?

    Yes. Cheapflights offers flight deals from Syracuse to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to St. Louis?

    Currently, December is the cheapest month in which you can book a flight from Syracuse to St. Louis (average of $203). Flying from Syracuse to St. Louis in May is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus

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Alternative routes for Syracuse to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Syracuse to St. Louis

Discover the top 3 airlines that operate flights from Syracuse to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$345FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$333FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$333FlexibilityNo cancel feeOn-timeN/A

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