What are the cheapest airlines flying from Syracuse to St. Louis round-trip?

According to our current data, Frontier ($245), American Airlines ($249), and Delta ($251) offers the cheapest pricing from Syracuse to St. Louis. Frontier is 35% cheaper than the average price of flights available within the next 90 days to this destination.

What is the cheapest day to fly from Syracuse to St. Louis?

Travelers seeking maximum savings on their Syracuse to St. Louis flight should consider departing on Friday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular airlines that fly from Syracuse to St. Louis?

American Airlines, Delta and United Airlines are the most popular airlines when flying from Syracuse to St. Louis.

What is the cheapest day to fly round-trip from Syracuse to St. Louis?

Saturday flights are found to be more expensive to fly from Syracuse to St. Louis. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to St. Louis.

How far in advance should I book a flight from Syracuse to St. Louis?

Users have found that booking a flight from Syracuse to St. Louis at least 25 days early can save you up to 38% on average compared to booking a flight this week. If booking 25 days before your flight isn’t an option for you, users have found flights from Syracuse to St. Louis for as little as $296 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $343 for flights departing within the next 3 days.

What is the cheapest month to fly from Syracuse to St. Louis?

February can be a great time to fly to St. Louis from Syracuse with a flight ticket averaging about $380. Cheapflights users have found deals in the month of February for as cheap as $223. The most expensive prices can be found in the month of December.

Can I find deals for flights from Syracuse to St. Louis that include hotel bookings?

Yes. In addition to deals on Syracuse to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Syracuse to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to St. Louis.

Can I find deals for business class flights from Syracuse to St. Louis?

Yes. Cheapflights offers flight deals from Syracuse to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$176+ Flights from Syracuse to St. Louis

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1. Tell us where you want to go

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2. Select your favorite providers

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3. Compare prices and book

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Cheapflights Tip: The best prices from Syracuse Hancock Intl to Lambert-St Louis are usually found in February or May, booked 74 days in advance, depart on a Friday or Saturday and return on a Tuesday

Cheap flight deals from Syracuse to St. Louis

Round-trip from	$245 (FlightHub)
One-way from	$176 (American Airlines)
Popular in	December
Cheapest in	February
Average price	$363

From Syracuse Hancock Intl to Lambert-St Louis

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One-way flight from Syracuse Hancock Intl to Lambert-St Louis

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Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Syracuse to St. Louis

Cheapest flights from Syracuse to St. Louis
Explore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 29, 2025.

jue. 8/219:37 pmSYR - STL

1 stop17h 44mFrontier

dom. 8/242:02 pmSTL - SYR

1 stop18h 26mFrontier

Deal found 7/27

$245

mié. 8/276:20 amSYR - STL

1 stop5h 50mDelta

mié. 9/35:25 pmSTL - SYR

1 stop4h 22mDelta

Deal found 7/28

$249

jue. 8/145:19 pmSYR - STL

1 stop7h 36mAmerican Airlines

dom. 8/316:00 amSTL - SYR

1 stop4h 40mAmerican Airlines

Deal found 7/26

$254

mié. 8/276:10 amSYR - STL

2 stops9h 23mUnited Airlines

vie. 9/53:20 pmSTL - SYR

1 stop4h 45mUnited Airlines

Deal found 7/28

$324

dom. 8/2412:38 pmSYR - STL

3 stops25h 54mMultiple Airlines

dom. 8/312:30 pmSTL - SYR

2 stops18h 10mMultiple Airlines

Deal found 7/26

$371

Best flights from Syracuse to St. Louis
Discover carefully curated flight deals from Syracuse to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated julio 29, 2025.

jue. 8/219:37 pmSYR - STL

1 stop17h 44mFrontier

dom. 8/242:02 pmSTL - SYR

1 stop18h 26mFrontier

Deal found 7/29

$245

jue. 8/215:50 pmSYR - STL

1 stop4h 12mAmerican Airlines

lun. 8/253:53 pmSTL - SYR

1 stop5h 06mAmerican Airlines

Deal found 7/27

$249

dom. 8/315:55 amSYR - STL

1 stop7h 36mDelta

mié. 9/36:00 amSTL - SYR

1 stop6h 10mDelta

Deal found 7/28

$251

mié. 8/276:10 amSYR - STL

2 stops9h 23mUnited Airlines

vie. 9/53:20 pmSTL - SYR

1 stop4h 45mUnited Airlines

Deal found 7/28

$324

dom. 8/2412:38 pmSYR - STL

3 stops25h 54mMultiple Airlines

dom. 8/312:30 pmSTL - SYR

2 stops18h 10mMultiple Airlines

Deal found 7/26

$371

Last-minute flights from Syracuse to St. Louis
Discover last-minute flight deals from Syracuse to St. Louis. Data last updated julio 29, 2025 and is based on user searches.

mar. 8/54:22 pmSYR - STL

1 stop5h 02mAmerican Airlines

mar. 8/128:43 amSTL - SYR

1 stop5h 00mAmerican Airlines

Deal found 7/27

$284

mié. 8/68:24 pmSYR - STL

3 stops23h 17mMultiple Airlines

mié. 8/139:20 amSTL - SYR

3 stops33h 26mMultiple Airlines

Deal found 7/28

$589

jue. 8/75:40 pmSYR - STL

1 stop6h 05mUnited Airlines

dom. 8/105:00 amSTL - SYR

2 stops8h 10mUnited Airlines

Deal found 7/27

$677

jue. 8/75:30 amSYR - STL

2 stops8h 04mDelta

dom. 8/107:00 amSTL - SYR

2 stops8h 58mDelta

Deal found 7/29

$1,308

jue. 8/145:19 pmSYR - STL

1 stop7h 36mAmerican Airlines

dom. 8/316:00 amSTL - SYR

1 stop4h 40mAmerican Airlines

Deal found 7/26

$254

jue. 8/219:37 pmSYR - STL

1 stop17h 44mFrontier

dom. 8/242:02 pmSTL - SYR

1 stop18h 26mFrontier

Deal found 7/27

$245

dom. 8/2412:38 pmSYR - STL

3 stops25h 54mMultiple Airlines

dom. 8/312:30 pmSTL - SYR

2 stops18h 10mMultiple Airlines

Deal found 7/26

$371

mié. 8/276:20 amSYR - STL

1 stop5h 50mDelta

mié. 9/35:25 pmSTL - SYR

1 stop4h 22mDelta

Deal found 7/28

$249

mié. 8/276:10 amSYR - STL

2 stops9h 23mUnited Airlines

vie. 9/53:20 pmSTL - SYR

1 stop4h 45mUnited Airlines

Deal found 7/28

$324

One-way flights from Syracuse to St. Louis
Search for one-way flight options from Syracuse to St. Louis. Find affordable one-way fares based on user searches. Data last updated julio 29, 2025.

mié. 8/66:04 amSYR - STL

1 stop4h 36mAmerican Airlines

Deal found 7/28

$176

mié. 8/68:24 pmSYR - STL

3 stops23h 17mMultiple Airlines

Deal found 7/28

$259

Fly from

Fly to

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

jue. 8/21

9:37 pm-2:21 pm

1 stop17h 44m

Lambert-St Louis

dom. 8/24

2:02 pm-9:28 am

1 stop18h 26m

$245

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

jue. 8/21

5:50 pm-9:02 pm

1 stop4h 12m

Lambert-St Louis

lun. 8/25

3:53 pm-9:59 pm

1 stop5h 06m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

dom. 8/31

5:55 am-12:31 pm

1 stop7h 36m

Lambert-St Louis

mié. 9/3

6:00 am-1:10 pm

1 stop6h 10m

$251

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

mié. 8/27

6:10 am-2:33 pm

2 stops9h 23m

Lambert-St Louis

vie. 9/5

3:20 pm-9:05 pm

1 stop4h 45m

$324

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

dom. 8/24

12:38 pm-1:32 pm

3 stops25h 54m

Lambert-St Louis

dom. 8/31

2:30 pm-9:40 am

2 stops18h 10m

$371

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

mié. 8/6

6:04 am-9:40 am

1 stop4h 36m

$176

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

mié. 8/6

8:24 pm-6:41 pm

3 stops23h 17m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Syracuse to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Syracuse with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to St. Louis

How far ahead should I book a flight from Syracuse to St. Louis?

To ensure you get the cheapest price possible for a flight from Syracuse to St. Louis, you should look to book at least 24 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Syracuse to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Syracuse to St. Louis (average of $311). Flying from Syracuse to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to STL?

Unlike in the afternoon, when flights are generally more expensive, you can save up to 32% on flights from Syracuse to St. Louis by exploring options for tickets in the evening.

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Syracuse to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Delta

8.0

Very good

7,979 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

United Airlines

7.4

Good

8,896 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

Frontier

5.9

Fair

3,238 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

Related info for your journey

What are the cheapest airlines flying from Syracuse to St. Louis round-trip?
According to our current data, Frontier ($245), American Airlines ($249), and Delta ($251) offers the cheapest pricing from Syracuse to St. Louis. Frontier is 35% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Syracuse to St. Louis that include hotel bookings?
Yes. In addition to deals on Syracuse to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Syracuse to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to St. Louis.
Can I find deals for business class flights from Syracuse to St. Louis?
Yes. Cheapflights offers flight deals from Syracuse to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Syracuse to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Syracuse to St. Louis (average of $311). Flying from Syracuse to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

O'Fallon

Maryland Heights

Fairview Heights

Collinsville

Eureka

St. Peters

Glencoe

Alton

Chesterfield

Festus

Farmington

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Syracuse to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$248	Average$375	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$248	Average$358	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$397	Average$553	FlexibilityNo cancel fee	On-time69%

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$176+ Cheap flights from Syracuse to St. Louis (SYR - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Syracuse to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Syracuse Hancock Intl to Lambert-St Louis are usually found in February or May, booked 74 days in advance, depart on a Friday or Saturday and return on a Tuesday

Cheap flight deals from Syracuse to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Syracuse to St. Louis

Cheapest flights from Syracuse to St. LouisExplore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 29, 2025.

Explore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Syracuse to St. Louis that are best for you.

Best time to book a flight from Syracuse to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Syracuse with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to St. Louis

How far ahead should I book a flight from Syracuse to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to St. Louis. Price data was last updated on July 25, 2025.

What is the cheapest month to book a flight from Syracuse to St. Louis?

What is the cheapest time of day to fly from SYR to STL?

Find hourly flight availability from Syracuse to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 29, 2025.

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Syracuse to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Syracuse to St. Louis round-trip?

Can I find deals for flights from Syracuse to St. Louis that include hotel bookings?

How can I find direct flights from Syracuse to St. Louis?

Can I find deals for business class flights from Syracuse to St. Louis?

What is the cheapest month to book a flight from Syracuse to St. Louis?

Traveling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Syracuse to St. Louis

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Top 3 airlines flying from Syracuse to St. Louis

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Cheapest flights from Syracuse to St. Louis
Explore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 29, 2025.