What are the cheapest airlines flying from Syracuse to St. Louis round-trip?

According to our current data, Delta ($249), American Airlines ($254), and United Airlines ($315) offers the cheapest pricing from Syracuse to St. Louis. Delta is 35% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Syracuse to St. Louis one-way?

$198 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $231 and $239, respectively.

What is the cheapest day to fly from Syracuse to St. Louis?

Travelers seeking maximum savings on their Syracuse to St. Louis flight should consider departing on Friday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from Syracuse to St. Louis?

American Airlines, Delta and United Airlines are the most popular airlines when flying from Syracuse to St. Louis.

What is the cheapest day to fly round-trip from Syracuse to St. Louis?

Saturday flights are found to be more expensive to fly from Syracuse to St. Louis. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to St. Louis.

How far in advance should I book a flight from Syracuse to St. Louis?

Users have found that booking a flight from Syracuse to St. Louis at least 25 days early can save you up to 38% on average compared to booking a flight this week. If booking 25 days before your flight isn’t an option for you, users have found flights from Syracuse to St. Louis for as little as $296 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $343 for flights departing within the next 3 days.

What is the cheapest month to fly from Syracuse to St. Louis?

February can be a great time to fly to St. Louis from Syracuse with a flight ticket averaging about $386. Cheapflights users have found deals in the month of February for as cheap as $223. The most expensive prices can be found in the month of December.

Can I find deals for flights from Syracuse to St. Louis that include hotel bookings?

Yes. In addition to deals on Syracuse to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Syracuse to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to St. Louis.

Can I find deals for business class flights from Syracuse to St. Louis?

Yes. Cheapflights offers flight deals from Syracuse to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$148+ Flights from Syracuse to St. Louis

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Syracuse Hancock Intl to Lambert-St Louis are usually found in February or July, booked 70 days in advance, depart on a Friday or Saturday and return on a Tuesday

Cheap flight deals from Syracuse to St. Louis

Round-trip from	$249 (Delta)
One-way from	$148 (Mytrip)
Popular in	December
Cheapest in	February
Average price	$391

From Syracuse Hancock Intl to Lambert-St Louis

Search Deals

One-way flight from Syracuse Hancock Intl to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).

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Average for round-trip flights in June 2025

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Find flight deals from Syracuse to St. Louis

Cheapest flights from Syracuse to St. Louis
Explore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Thu 8/2112:10 pmSYR - STL

1 stop4h 56mDelta

Wed 8/276:00 amSTL - SYR

1 stop4h 45mDelta

Deal found 6/11

$249

Mon 9/86:49 pmSYR - STL

1 stop5h 18mAmerican Airlines

Sat 9/135:55 amSTL - SYR

2 stops7h 55mAmerican Airlines

Deal found 6/12

$254

Wed 7/308:34 pmSYR - STL

1 stop20h 57mMultiple Airlines

Sun 8/310:47 amSTL - SYR

2 stops21h 09mMultiple Airlines

Deal found 6/10

$292

Wed 10/86:00 amSYR - STL

2 stops9h 27mUnited Airlines

Wed 10/155:24 pmSTL - SYR

1 stop4h 51mUnited Airlines

Deal found 6/11

$315

Mon 7/218:41 pmSYR - STL

1 stop28h 06mFrontier

Sun 7/272:36 pmSTL - SYR

1 stop20h 15mFrontier

Deal found 6/10

$330

Best flights from Syracuse to St. Louis
Discover carefully curated flight deals from Syracuse to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2025.

Thu 8/2112:10 pmSYR - STL

1 stop4h 56mDelta

Fri 8/293:42 pmSTL - SYR

1 stop7h 09mDelta

Deal found 6/11

$249

Mon 9/86:49 pmSYR - STL

1 stop5h 18mAmerican Airlines

Sat 9/135:55 amSTL - SYR

2 stops7h 55mAmerican Airlines

Deal found 6/12

$254

Wed 7/308:34 pmSYR - STL

1 stop20h 57mMultiple Airlines

Sun 8/310:47 amSTL - SYR

2 stops21h 09mMultiple Airlines

Deal found 6/10

$292

Wed 10/86:00 amSYR - STL

2 stops9h 27mUnited Airlines

Wed 10/155:24 pmSTL - SYR

1 stop4h 51mUnited Airlines

Deal found 6/11

$315

Mon 7/218:41 pmSYR - STL

1 stop28h 06mFrontier

Sun 7/272:36 pmSTL - SYR

1 stop20h 15mFrontier

Deal found 6/10

$330

Last-minute flights from Syracuse to St. Louis
Discover last-minute flight deals from Syracuse to St. Louis. Data last updated June 12, 2025 and is based on user searches.

Wed 6/186:00 amSYR - STL

2 stops7h 20mUnited Airlines

Mon 6/235:49 pmSTL - SYR

1 stop5h 09mUnited Airlines

Deal found 6/12

$460

Thu 6/198:21 pmSYR - STL

1 stop4h 33mAmerican Airlines

Sun 6/227:50 amSTL - SYR

1 stop7h 42mAmerican Airlines

Deal found 6/11

$393

Fri 6/205:50 amSYR - STL

1 stop4h 53mDelta

Mon 6/235:30 pmSTL - SYR

1 stop5h 27mDelta

Deal found 6/10

$309

Fri 6/2012:50 pmSYR - STL

2 stops12h 03mFrontier

Sun 6/222:27 pmSTL - SYR

2 stops20h 28mFrontier

Deal found 6/10

$659

Sun 6/223:04 pmSYR - STL

2 stops20h 29mMultiple Airlines

Thu 6/266:36 pmSTL - SYR

3 stops23h 06mMultiple Airlines

Deal found 6/12

$518

Fri 6/275:31 amSYR - STL

1 stop4h 55mAmerican Airlines

Tue 7/15:30 amSTL - SYR

2 stops6h 52mAmerican Airlines

Deal found 6/12

$264

Sun 7/206:00 amSYR - STL

2 stops9h 37mUnited Airlines

Sun 7/271:25 pmSTL - SYR

2 stops8h 50mUnited Airlines

Deal found 6/11

$403

Mon 7/218:41 pmSYR - STL

1 stop28h 06mFrontier

Sun 7/272:36 pmSTL - SYR

1 stop20h 15mFrontier

Deal found 6/10

$330

Wed 7/306:59 pmSYR - STL

1 stop5h 54mDelta

Sun 8/35:23 pmSTL - SYR

1 stop5h 26mDelta

Deal found 6/10

$249

Wed 7/308:34 pmSYR - STL

1 stop20h 57mMultiple Airlines

Sun 8/310:47 amSTL - SYR

2 stops21h 09mMultiple Airlines

Deal found 6/10

$292

One-way flights from Syracuse to St. Louis
Search for one-way flight options from Syracuse to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 12, 2025.

Thu 7/103:02 pmSYR - STL

2 stops19h 50mMultiple Airlines

Deal found 6/12

$148

Fri 6/209:49 pmSYR - STL

1 stop27h 04mFrontier

Deal found 6/11

$198

Wed 6/186:00 amSYR - STL

1 stop4h 37mDelta

Deal found 6/12

$231

Thu 7/105:46 pmSYR - STL

1 stop4h 33mAmerican Airlines

Deal found 6/12

$239

Fri 6/2010:25 amSYR - STL

2 stops12h 01mUnited Airlines

Deal found 6/11

$265

Cheapflights Fare Finder

Use the filters below to find and compare flights from Syracuse to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 8/21

12:10 pm-4:06 pm

1 stop4h 56m

Lambert-St Louis

Fri 8/29

3:42 pm-11:51 pm

1 stop7h 09m

$249

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Mon 9/8

6:49 pm-11:07 pm

1 stop5h 18m

Lambert-St Louis

Sat 9/13

5:55 am-2:50 pm

2 stops7h 55m

$254

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 7/30

8:34 pm-4:31 pm

1 stop20h 57m

Lambert-St Louis

Sun 8/3

10:47 am-8:56 am

2 stops21h 09m

$292

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 10/8

6:00 am-2:27 pm

2 stops9h 27m

Lambert-St Louis

Wed 10/15

5:24 pm-11:15 pm

1 stop4h 51m

$315

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Mon 7/21

8:41 pm-11:47 pm

1 stop28h 06m

Lambert-St Louis

Sun 7/27

2:36 pm-11:51 am

1 stop20h 15m

$330

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 7/10

3:02 pm-9:52 am

2 stops19h 50m

$148

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Fri 6/20

9:49 pm-11:53 pm

1 stop27h 04m

$198

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Wed 6/18

6:00 am-9:37 am

1 stop4h 37m

$231

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Thu 7/10

5:46 pm-9:19 pm

1 stop4h 33m

$239

SyracuseSt. Louis

SYR - STL

SYRSTL

Syracuse Hancock Intl

Fri 6/20

10:25 am-9:26 pm

2 stops12h 01m

$265

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from Syracuse to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Syracuse with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to St. Louis

How far ahead should I book a flight from Syracuse to St. Louis?

To ensure you get the cheapest price possible for a flight from Syracuse to St. Louis, you should look to book at least 24 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Syracuse to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Syracuse to St. Louis (average of $311). Flying from Syracuse to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to STL?

Unlike in the afternoon, when flights are generally more expensive, you can save up to 32% on flights from Syracuse to St. Louis by exploring options for tickets in the evening.

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Syracuse to St. Louis, such as Delta, United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Delta

8.0

Very good

7,950 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

United Airlines

7.4

Good

8,790 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

Frontier

5.9

Fair

3,295 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

Related info for your journey

What are the cheapest airlines flying from Syracuse to St. Louis round-trip?
According to our current data, Delta ($249), American Airlines ($254), and United Airlines ($315) offers the cheapest pricing from Syracuse to St. Louis. Delta is 35% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Syracuse to St. Louis one-way?
$198 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $231 and $239, respectively.
Can I find deals for flights from Syracuse to St. Louis that include hotel bookings?
Yes. In addition to deals on Syracuse to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Syracuse to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to St. Louis.
Can I find deals for business class flights from Syracuse to St. Louis?
Yes. Cheapflights offers flight deals from Syracuse to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Syracuse to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Syracuse to St. Louis (average of $311). Flying from Syracuse to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

O'Fallon

Maryland Heights

Fairview Heights

Collinsville

Eureka

St. Peters

Glencoe

Festus

Alton

Farmington

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Top 3 airlines flying from Syracuse to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$248	Average$376	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$248	Average$365	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$397	Average$551	FlexibilityNo cancel fee	On-time69%

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$148+ Cheap flights from Syracuse to St. Louis (SYR - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Syracuse to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Syracuse Hancock Intl to Lambert-St Louis are usually found in February or July, booked 70 days in advance, depart on a Friday or Saturday and return on a Tuesday

Cheap flight deals from Syracuse to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Syracuse to St. Louis

Cheapest flights from Syracuse to St. LouisExplore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Explore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Syracuse to St. Louis that are best for you.

Best time to book a flight from Syracuse to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Syracuse with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to St. Louis

How far ahead should I book a flight from Syracuse to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to St. Louis. Price data was last updated on June 9, 2025.

What is the cheapest month to book a flight from Syracuse to St. Louis?

What is the cheapest time of day to fly from SYR to STL?

Find hourly flight availability from Syracuse to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Syracuse to St. Louis, such as Delta, United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Syracuse to St. Louis round-trip?

What are the cheapest airlines to fly from Syracuse to St. Louis one-way?

Can I find deals for flights from Syracuse to St. Louis that include hotel bookings?

How can I find direct flights from Syracuse to St. Louis?

Can I find deals for business class flights from Syracuse to St. Louis?

What is the cheapest month to book a flight from Syracuse to St. Louis?

Traveling to a place near Syracuse?

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Alternative routes for Syracuse to St. Louis

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Top 3 airlines flying from Syracuse to St. Louis

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Cheapest flights from Syracuse to St. Louis
Explore the most affordable flight options available from Syracuse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.