HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
St. Louis

$453+ Cheap flights from Italy to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — STL
Jun 3 — Jun 101
Wed 6/3
Wed 6/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Italy to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Italy to St. Louis

Cheapest flights from Italy to St. Louis
Explore the most affordable flight options available from Italy to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.

This British Airways deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1712:15 pm
VCE
-
STL
1 stop14h 14m
British Airways
Sun 5/249:40 pm
STL
-
VCE
1 stop17h 35m
British Airways
Deal found 5/4$888
This British Airways deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:55 am
MXP
-
STL
1 stop16h 34m
British Airways
Tue 5/1212:59 pm
STL
-
MXP
1 stop14h 16m
British Airways
Deal found 5/1$896
This British Airways deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:30 pm
FCO
-
STL
1 stop17h 14m
British Airways
Sun 8/309:40 pm
STL
-
FCO
1 stop18h 00m
British Airways
Deal found 5/3$903
This British Airways deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:00 am
FCO
-
STL
1 stop19h 19m
British Airways
Sun 5/249:40 pm
STL
-
FCO
1 stop18h 00m
British Airways
Deal found 5/4$905
This Expedia deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:00 am
FCO
-
STL
1 stop15h 30m
British Airways
Wed 11/2510:45 am
STL
-
FCO
1 stop15h 15m
British Airways
Deal found 5/1$912
This Cheapflightsfares deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:20 am
FLR
-
STL
2 stops19h 34m
Lufthansa
Thu 12/101:27 pm
STL
-
FLR
2 stops17h 08m
Lufthansa
Deal found 5/3$920
This Cheapflightsfares deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:50 am
FCO
-
STL
2 stops21h 32m
Lufthansa
Sun 9/273:30 pm
STL
-
FCO
1 stop19h 20m
Lufthansa
Deal found 5/1$926
This lol.travel deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:20 pm
MXP
-
STL
1 stop15h 05m
Air Canada
Mon 5/111:05 pm
STL
-
MXP
1 stop14h 15m
Air Canada
Deal found 4/29$929
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:30 am
FLR
-
STL
2 stops19h 23m
United Airlines
Mon 6/18:35 am
STL
-
FLR
2 stops25h 00m
United Airlines
Deal found 4/30$944
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:05 am
FCO
-
STL
1 stop13h 50m
United Airlines
Sun 11/229:23 am
STL
-
FCO
1 stop15h 22m
United Airlines
Deal found 5/1$948
This Cheapflightsfares deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:50 am
FCO
-
STL
1 stop13h 35m
Multiple Airlines
Sun 9/271:00 pm
STL
-
FCO
1 stop12h 15m
Multiple Airlines
Deal found 5/1$949
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:30 am
MXP
-
STL
2 stops19h 24m
United Airlines
Sun 12/67:30 am
STL
-
MXP
1 stop17h 00m
United Airlines
Deal found 4/29$950

Find flight deals from Italy to St. Louis

Keep the following information in mind while searching for Italy to St. Louis flight deals. Data was last updated May 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$903
(British Airways)

One-way from

$453
(Kiwi.com)
Provider with most accurate pricing for Rome (ROM)-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Rome (ROM)-Lambert-St Louis flights.
Search Deals
From Italy to Lambert-St Louis
Search Deals
One-way flight from Italy to Lambert-St Louis
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Italy to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

VeniceSt. Louis

VCE - STL

VCESTL

Venice Marco Polo

Sun 5/17

12:15 pm-7:29 pm

1 stop14h 14m

Lambert-St Louis

Sun 5/24

9:40 pm-10:15 pm

1 stop17h 35m

$888

RomeSt. Louis

FCO - STL

FCOSTL

Rome Fiumicino

Thu 6/11

1:30 pm-11:44 pm

1 stop17h 14m

Lambert-St Louis

Sun 8/30

9:40 pm-10:40 pm

1 stop18h 00m

$903

RomeSt. Louis

FCO - STL

FCOSTL

Rome Fiumicino

Sun 9/20

6:50 am-6:41 pm

2 stops18h 51m

Lambert-St Louis

Sun 9/27

1:27 pm-1:15 pm

2 stops16h 48m

$955

MilanSt. Louis

MXP - STL

MXPSTL

Milan Malpensa

Thu 5/14

2:20 pm-12:48 pm

1 stop29h 28m

Lambert-St Louis

Tue 5/19

11:06 am-11:30 am

1 stop17h 24m

$957

FlorenceSt. Louis

FLR - STL

FLRSTL

Florence Peretola

Fri 5/15

9:50 am-10:30 pm

2 stops19h 40m

Lambert-St Louis

Mon 6/1

8:35 am-4:35 pm

2 stops25h 00m

$957

RomeSt. Louis

FCO - STL

FCOSTL

Rome Fiumicino

Thu 6/11

11:30 am-12:11 pm

2 stops31h 41m

Lambert-St Louis

Sun 8/30

12:10 pm-9:15 am

1 stop14h 05m

$958

VeniceSt. Louis

VCE - STL

VCESTL

Venice Marco Polo

Sun 5/17

11:05 am-9:13 pm

2 stops17h 08m

Lambert-St Louis

Sun 5/24

1:05 pm-12:00 pm

1 stop15h 55m

$968

MilanSt. Louis

MXP - STL

MXPSTL

Milan Malpensa

Thu 5/14

12:20 pm-10:45 pm

2 stops17h 25m

Lambert-St Louis

Tue 5/19

12:15 pm-12:15 pm

2 stops17h 00m

$987

FlorenceSt. Louis

FLR - STL

FLRSTL

Florence Peretola

Thu 5/14

6:30 am-8:25 pm

2 stops20h 55m

Lambert-St Louis

Sun 5/31

7:05 am-12:50 pm

2 stops22h 45m

$991
Quickest round-trip

RomeSt. Louis

FCO - STL

FCOSTL

Rome Fiumicino

Sun 10/25

7:05 am-2:55 pm

1 stop13h 50m

Lambert-St Louis

Sun 11/1

8:15 pm-5:55 pm

2 stops14h 40m

$997

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Italy to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to St. Louis
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Italy to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Italy?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to St. Louis from Italy.

  • How long is the flight from Italy to St. Louis?

    United Airlines, American Airlines, and British Airways can get you from Italy to St. Louis in just under 16h 36m. Your travel time can differ by up to 12h 52m. The distance from Italy to St. Louis is about 4924 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Italy to St. Louis one-way?

    One-way options have recently been found by users for as low as $505 on American Airlines. Other airlines that offer cheap prices include British Airways from $530 and Iberia from $577 one-way.

  • What are the most popular routes from Italy to St. Louis?

    Most travelers choose Rome Fiumicino - Lambert-St Louis, Bologna Guglielmo Marconi - Lambert-St Louis or Florence Peretola - Lambert-St Louis when deciding on the best route from Italy to St. Louis.

  • Can I find deals for flights from Italy to St. Louis that include hotel bookings?

    Yes. In addition to deals on Italy to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to St. Louis.

  • Can I find deals for business class flights from Italy to St. Louis?

    Yes. Cheapflights offers flight deals from Italy to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.