How long is the flight from Italy to St. Louis?

American Airlines, British Airways, and Iberia can get you from Italy to St. Louis in just under 26h 03m. Your travel time can differ by up to 26h 56m. The distance from Italy to St. Louis is about 4896 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Italy to St. Louis one-way?

One-way options have recently been found by users for as low as $507 on American Airlines. Other airlines that offer cheap prices include British Airways from $523 and Aer Lingus from $535 one-way.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular routes from Italy to St. Louis?

Most travelers choose Rome Fiumicino - Lambert-St Louis, Milan Linate - Lambert-St Louis or Milan Malpensa - Lambert-St Louis when deciding on the best route from Italy to St. Louis.

What is the cheapest time of day to fly from IT to STL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Italy to St. Louis as you normally would.

What airport do you fly into for flights to St. Louis from Italy?

Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to St. Louis from Italy.

Can I find deals for flights from Italy to St. Louis that include hotel bookings?

Yes. In addition to deals on Italy to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Italy to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to St. Louis.

Can I find deals for business class flights from Italy to St. Louis?

Yes. Cheapflights offers flight deals from Italy to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$351+ Flights from Italy to St. Louis

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Italy to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Italy to St. Louis

Cheapest flights from Italy to St. Louis
Explore the most affordable flight options available from Italy to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Wed 12/311:10 pmFCO - STL

1 stop28h 40mMultiple Airlines

Thu 6/255:06 pmSTL - FCO

1 stop11h 14mMultiple Airlines

Deal found 12/26

$1,082

Wed 12/315:15 pmLIN - STL

2 stops33h 15mBritish Airways

Wed 3/1811:59 amSTL - LIN

2 stops17h 31mBritish Airways

Deal found 12/26

$1,112

Tue 12/306:30 amLIN - STL

2 stops21h 11mDelta

Tue 3/1710:12 amSTL - LIN

2 stops16h 33mDelta

Deal found 12/26

$1,135

Tue 12/306:55 amMXP - STL

2 stops17h 06mDelta

Tue 3/1712:04 pmSTL - MXP

2 stops16h 31mDelta

Deal found 12/26

$1,136

Tue 12/3010:55 amLIN - STL

2 stops16h 46mMultiple Airlines

Wed 3/185:59 pmSTL - LIN

2 stops13h 56mMultiple Airlines

Deal found 12/26

$1,147

Wed 12/316:55 amMXP - STL

2 stops22h 21mDelta

Sat 3/215:57 pmSTL - MXP

2 stops14h 58mDelta

Deal found 12/26

$1,148

Tue 12/3011:05 amMXP - STL

1 stop17h 38mDelta

Mon 3/2312:04 pmSTL - MXP

2 stops20h 51mDelta

Deal found 12/26

$1,157

Tue 12/3010:55 amLIN - STL

2 stops16h 46mMultiple Airlines

Thu 3/195:59 pmSTL - LIN

2 stops13h 56mMultiple Airlines

Deal found 12/26

$1,158

Wed 12/316:30 amLIN - STL

2 stops24h 08mDelta

Tue 3/2410:50 amSTL - LIN

2 stops21h 05mDelta

Deal found 12/26

$1,159

Tue 12/306:55 amMXP - STL

2 stops17h 06mDelta

Mon 3/163:05 pmSTL - MXP

2 stops14h 35mDelta

Deal found 12/26

$1,160

Tue 12/3011:05 amMXP - STL

1 stop17h 38mDelta

Sat 3/215:00 pmSTL - MXP

1 stop33h 05mDelta

Deal found 12/26

$1,161

Tue 12/3011:05 amMXP - STL

1 stop17h 38mDelta

Sun 3/226:04 amSTL - MXP

1 stop20h 01mDelta

Deal found 12/26

$1,171

Best flights from Italy to St. Louis
Discover carefully curated flight deals from Italy to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Thu 5/79:10 pmPSA - STL

2 stops26h 03mAmerican Airlines

Mon 5/119:38 amSTL - PSA

2 stops19h 02mAmerican Airlines

Deal found 12/27

$722

Mon 1/198:15 pmBLQ - STL

2 stops52h 59mBritish Airways

Fri 1/305:04 pmSTL - BLQ

2 stops17h 31mBritish Airways

Deal found 12/27

$738

Wed 1/1411:35 amLIN - STL

2 stops42h 20mIberia

Sun 1/1811:05 amSTL - LIN

2 stops28h 55mIberia

Deal found 12/27

$802

Mon 1/197:00 pmMXP - STL

2 stops34h 59mMultiple Airlines

Fri 1/306:00 amSTL - MXP

2 stops19h 05mMultiple Airlines

Deal found 12/27

$814

Wed 1/146:10 amLIN - STL

1 stop14h 45mUnited Airlines

Sun 1/183:11 pmSTL - LIN

2 stops15h 59mUnited Airlines

Deal found 12/27

$843

Wed 2/119:45 amMXP - STL

1 stop21h 14mLufthansa

Wed 2/1811:39 amSTL - MXP

1 stop12h 51mLufthansa

Deal found 12/28

$852

Tue 1/131:30 pmFCO - STL

2 stops32h 59mAir Canada

Wed 10/219:10 amSTL - FCO

2 stops17h 05mAir Canada

Deal found 12/26

$864

Sun 1/1112:00 pmVCE - STL

2 stops18h 39mDelta

Sun 1/181:05 pmSTL - VCE

1 stop15h 15mDelta

Deal found 12/27

$939

Sun 1/118:25 pmVCE - STL

2 stops26h 49mAmerican Airlines

Sun 1/181:35 pmSTL - VCE

2 stops16h 45mAmerican Airlines

Deal found 12/27

$733

Mon 2/96:55 amVCE - STL

2 stops20h 18mBritish Airways

Mon 2/162:24 pmSTL - VCE

2 stops16h 06mBritish Airways

Deal found 12/26

$738

Wed 2/1110:25 amMXP - STL

2 stops18h 26mAmerican Airlines

Wed 2/185:52 pmSTL - MXP

2 stops19h 08mAmerican Airlines

Deal found 12/28

$736

Wed 1/217:00 pmMXP - STL

2 stops34h 59mMultiple Airlines

Fri 1/306:00 amSTL - MXP

2 stops19h 05mMultiple Airlines

Deal found 12/27

$814

Wed 1/146:10 amLIN - STL

1 stop14h 45mUnited Airlines

Mon 10/193:30 pmSTL - LIN

1 stop13h 30mUnited Airlines

Deal found 12/26

$844

Sun 1/113:15 pmVCE - STL

2 stops38h 43mLufthansa

Sun 1/183:50 pmSTL - VCE

1 stop11h 15mLufthansa

Deal found 12/27

$884

Wed 2/111:05 pmMXP - STL

2 stops16h 53mAir Canada

Wed 2/187:41 amSTL - MXP

3 stops19h 14mAir Canada

Deal found 12/28

$887

Thu 1/227:30 amFCO - STL

2 stops20h 45mAmerican Airlines

Mon 1/262:54 pmSTL - FCO

2 stops17h 01mAmerican Airlines

Deal found 12/25

$748

Mon 1/126:55 pmLIN - STL

2 stops28h 19mBritish Airways

Sun 1/181:35 pmSTL - LIN

2 stops17h 45mBritish Airways

Deal found 12/27

$841

Wed 1/146:10 amLIN - STL

1 stop14h 45mUnited Airlines

Wed 10/213:30 pmSTL - LIN

1 stop16h 10mUnited Airlines

Deal found 12/26

$844

Wed 1/711:35 amMXP - STL

2 stops34h 54mAir Canada

Wed 10/219:10 amSTL - MXP

2 stops18h 10mAir Canada

Deal found 12/26

$890

Mon 1/197:05 pmBLQ - STL

2 stops51h 24mMultiple Airlines

Fri 1/303:50 pmSTL - BLQ

1 stop15h 00mMultiple Airlines

Deal found 12/27

$895

Wed 1/146:10 amLIN - STL

1 stop14h 45mUnited Airlines

Tue 10/203:30 pmSTL - LIN

1 stop13h 30mUnited Airlines

Deal found 12/26

$844

Wed 1/711:35 amMXP - STL

2 stops34h 54mAir Canada

Mon 10/194:05 pmSTL - MXP

2 stops35h 15mAir Canada

Deal found 12/26

$890

Wed 1/147:05 amFCO - STL

1 stop13h 50mUnited Airlines

Fri 10/165:20 amSTL - FCO

1 stop24h 00mUnited Airlines

Deal found 12/26

$847

Mon 1/121:20 pmVCE - STL

2 stops17h 19mDelta

Fri 1/161:18 pmSTL - VCE

1 stop15h 02mDelta

Deal found 12/27

$1,214

Wed 1/147:05 amFCO - STL

1 stop13h 50mUnited Airlines

Thu 10/151:30 pmSTL - FCO

1 stop15h 50mUnited Airlines

Deal found 12/26

$847

Wed 1/147:05 amFCO - STL

1 stop13h 50mUnited Airlines

Tue 10/208:00 amSTL - FCO

1 stop16h 55mUnited Airlines

Deal found 12/26

$847

Sun 1/118:25 pmVCE - STL

2 stops33h 19mMultiple Airlines

Thu 1/1511:55 amSTL - VCE

2 stops29h 00mMultiple Airlines

Deal found 12/26

$1,135

Mon 1/1211:45 amVCE - STL

2 stops30h 18mAmerican Airlines

Fri 1/163:37 pmSTL - VCE

2 stops18h 18mAmerican Airlines

Deal found 12/27

$1,040

Wed 2/1110:35 amMXP - STL

2 stops36h 27mUnited Airlines

Wed 2/1811:39 amSTL - MXP

1 stop12h 51mUnited Airlines

Deal found 12/28

$848

Sun 1/118:25 pmVCE - STL

2 stops31h 07mAmerican Airlines

Thu 1/151:35 pmSTL - VCE

2 stops20h 05mAmerican Airlines

Deal found 12/26

$1,040

Last-minute flights from Italy to St. Louis
Discover last-minute flight deals from Italy to St. Louis. Data last updated December 28, 2025 and is based on user searches.

Thu 1/82:15 pmLIN - STL

2 stops31h 42mAmerican Airlines

Mon 1/121:35 pmSTL - LIN

2 stops17h 55mAmerican Airlines

Deal found 12/28

$735

Sun 1/118:25 pmVCE - STL

2 stops26h 49mAmerican Airlines

Sun 1/181:35 pmSTL - VCE

2 stops16h 45mAmerican Airlines

Deal found 12/27

$733

Mon 1/1211:55 amMXP - STL

2 stops41h 39mMultiple Airlines

Wed 10/213:30 pmSTL - MXP

1 stop12h 05mMultiple Airlines

Deal found 12/26

$755

Mon 1/1211:55 amMXP - STL

2 stops41h 39mMultiple Airlines

Sun 10/183:30 pmSTL - MXP

1 stop12h 05mMultiple Airlines

Deal found 12/26

$756

Mon 1/1211:20 amMXP - STL

2 stops30h 43mAmerican Airlines

Sun 1/181:35 pmSTL - MXP

2 stops21h 50mAmerican Airlines

Deal found 12/27

$759

Mon 1/1211:55 amMXP - STL

2 stops41h 39mMultiple Airlines

Wed 3/254:50 pmSTL - MXP

1 stop15h 05mMultiple Airlines

Deal found 12/26

$786

Mon 1/125:15 pmLIN - STL

2 stops35h 00mBritish Airways

Sat 3/282:25 pmSTL - LIN

2 stops24h 10mBritish Airways

Deal found 12/26

$821

Wed 1/1411:35 amLIN - STL

2 stops42h 20mIberia

Sun 1/1811:05 amSTL - LIN

2 stops28h 55mIberia

Deal found 12/27

$802

Mon 1/198:15 pmBLQ - STL

2 stops52h 59mBritish Airways

Fri 1/305:04 pmSTL - BLQ

2 stops17h 31mBritish Airways

Deal found 12/27

$738

Mon 1/197:00 pmMXP - STL

2 stops31h 29mMultiple Airlines

Fri 1/307:00 amSTL - MXP

1 stop18h 05mMultiple Airlines

Deal found 12/27

$814

Wed 1/216:10 amLIN - STL

1 stop14h 45mLufthansa

Fri 1/306:40 pmSTL - LIN

2 stops36h 25mLufthansa

Deal found 12/27

$828

Thu 1/227:30 amFCO - STL

2 stops20h 45mAmerican Airlines

Mon 1/2611:55 amSTL - FCO

2 stops17h 55mAmerican Airlines

Deal found 12/27

$748

One-way flights from Italy to St. Louis
Search for one-way flight options from Italy to St. Louis. Find affordable one-way fares based on user searches. Data last updated December 28, 2025.

Thu 3/58:25 amFCO - STL

3 stops45h 54mMultiple Airlines

Deal found 12/27

$351

Mon 1/125:45 pmMXP - STL

3 stops59h 49mMultiple Airlines

Deal found 12/26

$427

Tue 1/1311:55 amMXP - STL

3 stops41h 39mMultiple Airlines

Deal found 12/26

$428

Wed 1/146:20 amMXP - STL

3 stops47h 14mMultiple Airlines

Deal found 12/26

$431

Thu 1/155:45 pmMXP - STL

3 stops59h 49mMultiple Airlines

Deal found 12/26

$432

Sun 1/119:15 pmMXP - STL

3 stops56h 19mMultiple Airlines

Deal found 12/26

$503

Thu 1/158:50 pmLIN - STL

3 stops56h 44mMultiple Airlines

Deal found 12/26

$505

Wed 5/207:05 pmFCO - STL

2 stops30h 55mMultiple Airlines

Deal found 12/26

$520

Sun 5/37:10 amFLR - STL

1 stop19h 20mBritish Airways

Deal found 12/26

$525

Wed 6/38:45 amVCE - STL

1 stop17h 45mMultiple Airlines

Deal found 12/27

$532

Wed 6/31:40 pmVCE - STL

1 stop13h 32mBritish Airways

Deal found 12/26

$533

Mon 3/236:05 pmVCE - STL

2 stops29h 56mBritish Airways

Deal found 12/26

$535

Find flight deals from Italy to St. Louis

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$722 (American Airlines)
One-way from	$427 (Kiwi.com)

Provider with most accurate pricing for Rome (ROM)-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Rome (ROM)-Lambert-St Louis flights.

Search Deals

From Italy to Lambert-St Louis

Search Deals

One-way flight from Italy to Lambert-St Louis

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

PisaSt. Louis

PSA - STL

PSASTL

Pisa Gal Galilei

Thu 5/7

9:10 pm-4:13 pm

2 stops26h 03m

Lambert-St Louis

Mon 5/11

9:38 am-11:40 am

2 stops19h 02m

$722

VeniceSt. Louis

VCE - STL

VCESTL

Venice Marco Polo

Sun 1/11

8:25 pm-4:14 pm

2 stops26h 49m

Lambert-St Louis

Sun 1/18

1:35 pm-1:20 pm

2 stops16h 45m

$733

MilanSt. Louis

MXP - STL

MXPSTL

Milan Malpensa

Wed 2/11

10:25 am-9:51 pm

2 stops18h 26m

Lambert-St Louis

Wed 2/18

5:52 pm-8:00 pm

2 stops19h 08m

$736

BolognaSt. Louis

BLQ - STL

BLQSTL

Bologna Guglielmo Marconi

Mon 1/19

8:15 pm-6:14 pm

2 stops52h 59m

Lambert-St Louis

Fri 1/30

5:04 pm-5:35 pm

2 stops17h 31m

$738

VeniceSt. Louis

VCE - STL

VCESTL

Venice Marco Polo

Mon 2/9

6:55 am-8:13 pm

2 stops20h 18m

Lambert-St Louis

Mon 2/16

2:24 pm-1:30 pm

2 stops16h 06m

$738

RomeSt. Louis

FCO - STL

FCOSTL

Rome Fiumicino

Thu 1/22

7:30 am-9:15 pm

2 stops20h 45m

Lambert-St Louis

Mon 1/26

2:54 pm-2:55 pm

2 stops17h 01m

$748

MilanSt. Louis

LIN - STL

LINSTL

Milan Linate

Wed 1/14

11:35 am-10:55 pm

2 stops42h 20m

Lambert-St Louis

Sun 1/18

11:05 am-11:00 pm

2 stops28h 55m

$802

MilanSt. Louis

MXP - STL

MXPSTL

Milan Malpensa

Mon 1/19

7:00 pm-10:59 pm

2 stops34h 59m

Lambert-St Louis

Fri 1/30

6:00 am-8:05 am

2 stops19h 05m

$814

MilanSt. Louis

MXP - STL

MXPSTL

Milan Malpensa

Wed 1/21

7:00 pm-10:59 pm

2 stops34h 59m

Lambert-St Louis

Fri 1/30

6:00 am-8:05 am

2 stops19h 05m

$814

MilanSt. Louis

LIN - STL

LINSTL

Milan Linate

Mon 1/12

6:55 pm-4:14 pm

2 stops28h 19m

Lambert-St Louis

Sun 1/18

1:35 pm-2:20 pm

2 stops17h 45m

$841

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 60 results

...

Best time to book a flight from Italy to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Italy with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to St. Louis

What is the cheapest month to book a flight from Italy to St. Louis?

Currently, April is the cheapest month in which you can book a flight from Italy to St. Louis (average of $793). Flying from Italy to St. Louis in November is currently the most expensive (average of $1,471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

What airport do you fly into for flights to St. Louis from Italy?
Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to St. Louis from Italy.
How long is the flight from Italy to St. Louis?
American Airlines, British Airways, and Iberia can get you from Italy to St. Louis in just under 26h 03m. Your travel time can differ by up to 26h 56m. The distance from Italy to St. Louis is about 4896 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from Italy to St. Louis one-way?
One-way options have recently been found by users for as low as $507 on American Airlines. Other airlines that offer cheap prices include British Airways from $523 and Aer Lingus from $535 one-way.
What are the most popular routes from Italy to St. Louis?
Most travelers choose Rome Fiumicino - Lambert-St Louis, Milan Linate - Lambert-St Louis or Milan Malpensa - Lambert-St Louis when deciding on the best route from Italy to St. Louis.
Can I find deals for flights from Italy to St. Louis that include hotel bookings?
Yes. In addition to deals on Italy to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Italy to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to St. Louis.
Can I find deals for business class flights from Italy to St. Louis?
Yes. Cheapflights offers flight deals from Italy to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Italy to St. Louis?
Currently, April is the cheapest month in which you can book a flight from Italy to St. Louis (average of $793). Flying from Italy to St. Louis in November is currently the most expensive (average of $1,471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Edwardsville

O'Fallon

Swansea

Fairview Heights

Maryland Heights

Collinsville

Eureka

Glencoe

Chesterfield

Alton

Farmington

Festus

Browse thousands of different options on Cheapflights for your next trip

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$351+ Cheap flights from Italy to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Italy to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Italy to St. Louis

Cheapest flights from Italy to St. LouisExplore the most affordable flight options available from Italy to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Explore the most affordable flight options available from Italy to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Find flight deals from Italy to St. Louis

Keep the following information in mind while searching for Italy to St. Louis flight deals. Data was last updated December 28, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Italy to St. Louis that are best for you.

Best time to book a flight from Italy to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Italy with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Italy to St. Louis

What is the cheapest month to book a flight from Italy to St. Louis?

Related info for your journey

Find useful and relevant information for your journey from Italy to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Italy?

How long is the flight from Italy to St. Louis?

What are the cheapest airlines to fly from Italy to St. Louis one-way?

What are the most popular routes from Italy to St. Louis?

Can I find deals for flights from Italy to St. Louis that include hotel bookings?

How can I find direct flights from Italy to St. Louis?

Can I find deals for business class flights from Italy to St. Louis?

What is the cheapest month to book a flight from Italy to St. Louis?

Traveling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Italy to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Italy to St. Louis
Explore the most affordable flight options available from Italy to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.