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$108+ Cheap flights from Indianapolis to St. Louis (IND - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Oct 14 — Oct 211
Tue 10/14
Tue 10/21
1 adult, Economy
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Cheap flight deals from Indianapolis to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2025.

Round-trip from

$153
(Frontier)

One-way from

$108
(Frontier)

Popular in

September

Cheapest in

November

Average price

$556
From Indianapolis to Lambert-St Louis
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One-way flight from Indianapolis to Lambert-St Louis
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Highest demand for flights based on searches. 9% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Indianapolis to St. Louis

Cheapest flights from Indianapolis to St. Louis
Explore the most affordable flight options available from Indianapolis to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2025.

This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/712:17 pmIND - STL
1 stop4h 44mFrontier
Sun 11/911:23 amSTL - IND
1 stop22h 59mFrontier
Deal found 9/14$153
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:06 pmIND - STL
2 stops22h 00mFrontier
Sun 9/284:00 pmSTL - IND
1 stop18h 11mFrontier
Deal found 9/13$186
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/288:54 pmIND - STL
1 stop13h 12mFrontier
Thu 10/27:55 pmSTL - IND
1 stop23h 09mFrontier
Deal found 9/13$207
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:44 pmIND - STL
2 stops14h 22mFrontier
Sun 10/510:39 amSTL - IND
1 stop6h 48mFrontier
Deal found 9/14$215
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/77:00 amIND - STL
1 stop4h 26mDelta
Tue 10/141:30 pmSTL - IND
1 stop4h 45mDelta
Deal found 9/13$237
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:56 pmIND - STL
1 stop6h 02mAmerican Airlines
Sat 10/186:00 amSTL - IND
1 stop5h 08mAmerican Airlines
Deal found 9/14$287

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from Indianapolis to St. Louis that are best for you.

Fly from

Indianapolis

Fly to

St. Louis

Route

Depart

Return

Price

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Fri 11/7

12:17 pm-4:01 pm

1 stop4h 44m

Lambert-St Louis

Sun 11/9

11:23 am-11:22 am

1 stop22h 59m

$153

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Fri 9/26

12:06 pm-9:06 am

2 stops22h 00m

Lambert-St Louis

Sun 9/28

4:00 pm-11:11 am

1 stop18h 11m

$186

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Sun 9/28

8:54 pm-9:06 am

1 stop13h 12m

Lambert-St Louis

Thu 10/2

7:55 pm-8:04 pm

1 stop23h 09m

$207

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Fri 10/3

7:44 pm-9:06 am

2 stops14h 22m

Lambert-St Louis

Sun 10/5

10:39 am-6:27 pm

1 stop6h 48m

$215

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Tue 10/7

7:00 am-10:26 am

1 stop4h 26m

Lambert-St Louis

Tue 10/14

1:30 pm-7:15 pm

1 stop4h 45m

$237

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Sat 10/11

6:56 pm-11:58 pm

1 stop6h 02m

Lambert-St Louis

Sat 10/18

6:00 am-12:08 pm

1 stop5h 08m

$287

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Tue 3/10

1:48 pm-6:04 pm

1 stop5h 16m

Lambert-St Louis

Wed 3/11

7:05 pm-11:57 pm

1 stop3h 52m

$317

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Fri 10/10

8:51 am-5:10 pm

1 stop9h 19m

$108

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Sat 9/20

5:01 pm-9:06 am

1 stop17h 05m

$111

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Sat 9/20

11:10 am-3:04 pm

3 stops28h 54m

$176

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 11 results
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Best time to book a flight from Indianapolis to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to St. Louis

What is the cheapest month to book a flight from Indianapolis to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Indianapolis to St. Louis (average of $311). Flying from Indianapolis to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to STL?

Find hourly flight availability from Indianapolis to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2025.

A simple way to save on the total cost of your ticket is to fly from Indianapolis to St. Louis in the evening. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight at noon.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 14, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Indianapolis to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,956 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,956 reviews
Delta
8.0
Very good
7,956 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,956 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indianapolis to St. Louis?

    For as low as $153, Frontier can have you in St. Louis from Indianapolis in 4h 44m. Indianapolis and St. Louis are separated by a distance of 228 mi.

  • What are the cheapest airlines flying from Indianapolis to St. Louis round-trip?

    Flying on American Airlines is currently your cheapest option to St. Louis, with prices starting at $248. Another option worth looking into is Delta, starting at $266 round trip. American Airlines is 37% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Indianapolis to St. Louis that include hotel bookings?

    Yes. In addition to deals on Indianapolis to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to St. Louis.

  • Can I find deals for business class flights from Indianapolis to St. Louis?

    Yes. Cheapflights offers flight deals from Indianapolis to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Indianapolis to St. Louis (average of $311). Flying from Indianapolis to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indianapolis to St. Louis

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Top 2 airlines flying from Indianapolis to St. Louis

Discover the top 2 airlines that operate flights from Indianapolis to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$345FlexibilityNo cancel feeOn-time71%
DeltaCheapest$266Average$460FlexibilityNo cancel feeOn-timeN/A

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