What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to St. Louis round-trip?

Our cheapest airline available from Detroit Metropolitan Wayne County Airport to St. Louis is Spirit Airlines. Our recent data shows that you can find tickets from as low as $70 on this airline. Additional options worth looking into are Delta and Southwest, starting at $139 and $167 round-trip. You may be able to fly from Detroit Metropolitan Wayne County Airport to St. Louis for 77% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to St. Louis one-way?

One-way options have recently been found by users for as low as $28 on Spirit Airlines. Other airlines that offer cheap prices include Delta from $61 and Southwest from $79 one-way.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to St. Louis?

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to St. Louis flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

What are the cheapest flights from Detroit Metropolitan Wayne County Airport to St. Louis?

On average you can expect to pay $211 for a flight from Detroit Metropolitan Wayne County Airport to St. Louis. The cheapest flight overall is $48 while the most popular route, (Detroit Metropolitan Wayne County - Lambert-St Louis) is currently priced at $58.

What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to St. Louis?

No one likes to see their flight delayed. When booking a flight from Detroit Metropolitan Wayne County Airport to St. Louis consider choosing Korean Air (90%), Air France (84%) or Southwest (83%) as they are the most reliable in getting you off to your destination on time.

What are the most popular airlines that fly from Detroit Metropolitan Wayne County Airport to St. Louis?

Before booking your flight from Detroit Metropolitan Wayne County Airport to St. Louis check out the most popular airlines for this route: American Airlines, Delta or Frontier.

What is the cheapest day to fly round-trip from Detroit Metropolitan Wayne County Airport to St. Louis?

Sunday flights are found to be more expensive to fly from Detroit Metropolitan Wayne County Airport to St. Louis. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to St. Louis.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to St. Louis?

Flights from Detroit Metropolitan Wayne County Airport to St. Louis lean towards being more expensive in September. Prices are generally better when you fly from Detroit Metropolitan Wayne County Airport to St. Louis in June, with the cheapest ticket starting at $60.

What airports do I use to fly from Detroit to St. Louis?

If you book a flight from Detroit to St. Louis, you will be flying from Detroit Metropolitan Wayne County to Lambert-St Louis. Flights to Lambert-St Louis (STL) from Detroit Metropolitan Wayne County (DTW) take 1h 31m for a nonstop flight. There are 13 flights from Detroit Metropolitan Wayne County to St. Louis per day from 6 airlines.

Can I find deals for flights from Detroit to St. Louis that include hotel bookings?

Yes. In addition to deals on Detroit to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Detroit to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to St. Louis.

Can I find deals for business class flights from Detroit to St. Louis?

Yes. Cheapflights offers flight deals from Detroit to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$28+ Flights from Detroit Metropolitan Wayne County Airport to St. Louis

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Detroit to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Lambert-St Louis are usually found in June or May, booked 69 days in advance, depart on a Friday or Thursday and return on a Friday

Cheap flight deals from Detroit to St. Louis

Round-trip from	$70 (Kiwi.com)
One-way from	$28 (FlightHub)
Popular in	October
Cheapest in	June
Average price	$220
Good round-trip deal	$122 or less
Good one-way deal	$139 or less

From Detroit Metropolitan Wayne County to Lambert-St Louis

Search Deals

One-way flight from Detroit Metropolitan Wayne County to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 8% potential increase in price ($28 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in June 2025

Search Deals

Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Lambert-St Louis.

Search Deals

Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Lambert-St Louis.

Search Deals

Find flight deals from Detroit to St. Louis

Cheapest flights from Detroit to St. Louis
Explore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Mon 6/305:47 pmDTW - STL

Nonstop1h 31mSpirit Airlines

Thu 7/1010:47 amSTL - DTW

Nonstop1h 29mSpirit Airlines

Deal found 6/10

$70

Wed 8/138:55 amDTW - STL

Nonstop1h 37mDelta

Mon 8/186:40 amSTL - DTW

Nonstop1h 33mDelta

Deal found 6/10

$139

Sun 7/1311:28 amDTW - STL

1 stop9h 03mMultiple Airlines

Mon 7/2110:47 amSTL - DTW

Nonstop1h 29mMultiple Airlines

Deal found 6/9

$158

Tue 8/126:15 amDTW - STL

1 stop4h 20mSouthwest

Tue 8/195:25 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 6/10

$167

Fri 8/83:12 pmDTW - STL

1 stop6h 06mAmerican Airlines

Mon 8/118:40 amSTL - DTW

1 stop5h 49mAmerican Airlines

Deal found 6/11

$182

Wed 8/138:50 amDTW - STL

1 stop4h 37mUnited Airlines

Thu 8/148:00 amSTL - DTW

1 stop6h 32mUnited Airlines

Deal found 6/10

$237

Thu 7/39:36 amDTW - STL

1 stop5h 04mFrontier

Sat 7/511:00 amSTL - DTW

1 stop20h 50mFrontier

Deal found 6/11

$264

Best flights from Detroit to St. Louis
Discover carefully curated flight deals from Detroit to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2025.

Mon 6/305:47 pmDTW - STL

Nonstop1h 31mSpirit Airlines

Thu 7/1010:47 amSTL - DTW

Nonstop1h 29mSpirit Airlines

Deal found 6/10

$70

Wed 8/138:55 amDTW - STL

Nonstop1h 37mDelta

Mon 8/186:40 amSTL - DTW

Nonstop1h 33mDelta

Deal found 6/10

$139

Sun 7/1311:28 amDTW - STL

1 stop9h 03mMultiple Airlines

Mon 7/2110:47 amSTL - DTW

Nonstop1h 29mMultiple Airlines

Deal found 6/9

$158

Tue 8/126:15 amDTW - STL

1 stop4h 20mSouthwest

Tue 8/195:25 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 6/10

$167

Fri 8/83:12 pmDTW - STL

1 stop6h 06mAmerican Airlines

Mon 8/118:40 amSTL - DTW

1 stop5h 49mAmerican Airlines

Deal found 6/11

$182

Wed 8/138:50 amDTW - STL

1 stop4h 37mUnited Airlines

Thu 8/148:00 amSTL - DTW

1 stop6h 32mUnited Airlines

Deal found 6/10

$237

Thu 7/39:36 amDTW - STL

1 stop5h 04mFrontier

Sat 7/511:00 amSTL - DTW

1 stop20h 50mFrontier

Deal found 6/11

$264

Last-minute flights from Detroit to St. Louis
Discover last-minute flight deals from Detroit to St. Louis. Data last updated June 12, 2025 and is based on user searches.

Tue 6/1712:45 pmDTW - STL

Nonstop1h 41mDelta

Thu 7/36:00 pmSTL - DTW

Nonstop1h 30mDelta

Deal found 6/10

$360

Tue 6/178:20 pmDTW - STL

1 stop3h 45mSouthwest

Wed 7/25:45 pmSTL - DTW

1 stop5h 05mSouthwest

Deal found 6/10

$429

Tue 6/176:09 pmDTW - STL

1 stop5h 36mUnited Airlines

Thu 7/311:25 amSTL - DTW

1 stop4h 48mUnited Airlines

Deal found 6/10

$480

Wed 6/181:17 pmDTW - STL

1 stop11h 36mMultiple Airlines

Thu 7/36:36 pmSTL - DTW

Nonstop1h 28mMultiple Airlines

Deal found 6/10

$224

Thu 6/199:36 amDTW - STL

1 stop5h 04mFrontier

Tue 6/245:47 pmSTL - DTW

1 stop17h 35mFrontier

Deal found 6/12

$310

Fri 6/204:33 pmDTW - STL

Nonstop1h 31mSpirit Airlines

Mon 6/237:13 pmSTL - DTW

Nonstop1h 28mSpirit Airlines

Deal found 6/9

$133

Mon 6/305:47 pmDTW - STL

Nonstop1h 31mSpirit Airlines

Thu 7/1010:47 amSTL - DTW

Nonstop1h 29mSpirit Airlines

Deal found 6/10

$70

Thu 7/34:33 pmDTW - STL

Nonstop1h 31mMultiple Airlines

Sun 7/66:36 amSTL - DTW

1 stop26h 55mMultiple Airlines

Deal found 6/10

$157

Thu 7/39:36 amDTW - STL

1 stop5h 04mFrontier

Sat 7/511:00 amSTL - DTW

1 stop20h 50mFrontier

Deal found 6/11

$264

Tue 7/228:55 amDTW - STL

Nonstop1h 38mDelta

Mon 7/286:04 pmSTL - DTW

Nonstop1h 35mDelta

Deal found 6/10

$160

Thu 7/249:10 pmDTW - STL

Nonstop1h 35mSouthwest

Sun 7/274:55 pmSTL - DTW

1 stop6h 30mSouthwest

Deal found 6/10

$170

Thu 7/247:31 pmDTW - STL

1 stop5h 28mAmerican Airlines

Sun 7/277:23 amSTL - DTW

1 stop3h 45mAmerican Airlines

Deal found 6/12

$187

One-way flights from Detroit to St. Louis
Search for one-way flight options from Detroit to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 12, 2025.

Fri 7/119:20 amDTW - STL

Nonstop1h 32mSpirit Airlines

Deal found 6/10

$28

Fri 7/188:55 amDTW - STL

Nonstop1h 38mDelta

Deal found 6/9

$61

Tue 8/127:40 amDTW - STL

Nonstop1h 35mSouthwest

Deal found 6/9

$79

Wed 8/279:20 amDTW - STL

1 stop6h 13mUnited Airlines

Deal found 6/10

$89

Mon 7/217:31 pmDTW - STL

1 stop5h 28mAmerican Airlines

Deal found 6/10

$94

Sun 7/138:03 amDTW - STL

2 stops11h 38mMultiple Airlines

Deal found 6/10

$128

Sat 6/2112:59 pmDTW - STL

1 stop11h 54mFrontier

Deal found 6/9

$141

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 6/30

5:47 pm-6:18 pm

Nonstop1h 31m

Lambert-St Louis

Thu 7/10

10:47 am-1:16 pm

Nonstop1h 29m

$70

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 8/13

8:55 am-9:32 am

Nonstop1h 37m

Lambert-St Louis

Mon 8/18

6:40 am-9:13 am

Nonstop1h 33m

$139

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Sun 7/13

11:28 am-7:31 pm

1 stop9h 03m

Lambert-St Louis

Mon 7/21

10:47 am-1:16 pm

Nonstop1h 29m

$158

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Tue 8/12

6:15 am-9:35 am

1 stop4h 20m

Lambert-St Louis

Tue 8/19

5:25 pm-7:55 pm

Nonstop1h 30m

$167

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 8/8

3:12 pm-8:18 pm

1 stop6h 06m

Lambert-St Louis

Mon 8/11

8:40 am-3:29 pm

1 stop5h 49m

$182

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 8/13

8:50 am-12:27 pm

1 stop4h 37m

Lambert-St Louis

Thu 8/14

8:00 am-3:32 pm

1 stop6h 32m

$237

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Thu 7/3

9:36 am-1:40 pm

1 stop5h 04m

Lambert-St Louis

Sat 7/5

11:00 am-8:50 am

1 stop20h 50m

$264

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 7/11

9:20 am-9:52 am

Nonstop1h 32m

$28

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 7/18

8:55 am-9:33 am

Nonstop1h 38m

$61

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Tue 8/12

7:40 am-8:15 am

Nonstop1h 35m

$79

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 14 results

The best insider tips for Detroit Metropolitan Wayne County Airport to St. Louis flights

Cheapflights partnered with top experts to bring you the best recommendations for your Detroit Metropolitan Wayne County Airport to St. Louis trip

Airports

DTW

At DTW, security lines are generally short, with waits rarely exceeding 10 minutes in McNamara Terminal, making it efficient for business travelers.

STL

Use the MetroLink light rail from STL for a convenient, economical ride to downtown St. Louis, taking about 40 minutes.

Our travel experts

Brandon Schultz

Expert on DTW

Taryn White

Expert on STL

Best time to book a flight from Detroit to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Detroit with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to St. Louis

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to St. Louis?

The price you pay for your flight from Detroit Metropolitan Wayne County Airport to St. Louis may vary depending on when you book. For the best chance of a lower fare, look to book 69 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to St. Louis (average of $311). Flying from Detroit Metropolitan Wayne County Airport to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to STL?

Unlike at noon, when flights are generally more expensive, you can save up to 8% on flights from Detroit Metropolitan Wayne County Airport to St. Louis by exploring options for tickets in the afternoon.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to St. Louis

The most flights from DTW to STL are scheduled on a Thursday (18 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in St. Louis by month

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Detroit to St. Louis by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Southwest

8.0

Very good

4,287 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Delta

8.0

Very good

7,950 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

United Airlines

7.4

Good

8,790 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Spirit Airlines

6.3

Okay

8,052 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

What airports do I use to fly from Detroit to St. Louis?
If you book a flight from Detroit to St. Louis, you will be flying from Detroit Metropolitan Wayne County to Lambert-St Louis. Flights to Lambert-St Louis (STL) from Detroit Metropolitan Wayne County (DTW) take 1h 31m for a nonstop flight. There are 13 flights from Detroit Metropolitan Wayne County to St. Louis per day from 6 airlines.
What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to St. Louis round-trip?
Our cheapest airline available from Detroit Metropolitan Wayne County Airport to St. Louis is Spirit Airlines. Our recent data shows that you can find tickets from as low as $70 on this airline. Additional options worth looking into are Delta and Southwest, starting at $139 and $167 round-trip. You may be able to fly from Detroit Metropolitan Wayne County Airport to St. Louis for 77% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to St. Louis one-way?
One-way options have recently been found by users for as low as $28 on Spirit Airlines. Other airlines that offer cheap prices include Delta from $61 and Southwest from $79 one-way.
What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to St. Louis?
No one likes to see their flight delayed. When booking a flight from Detroit Metropolitan Wayne County Airport to St. Louis consider choosing Korean Air (90%), Air France (84%) or Southwest (83%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Detroit Metropolitan Wayne County Airport to St. Louis?
On average you can expect to pay $211 for a flight from Detroit Metropolitan Wayne County Airport to St. Louis. The cheapest flight overall is $48 while the most popular route, (Detroit Metropolitan Wayne County - Lambert-St Louis) is currently priced at $58.
Can I find deals for flights from Detroit to St. Louis that include hotel bookings?
Yes. In addition to deals on Detroit to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Detroit to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to St. Louis.
Can I find deals for business class flights from Detroit to St. Louis?
Yes. Cheapflights offers flight deals from Detroit to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to St. Louis (average of $311). Flying from Detroit Metropolitan Wayne County Airport to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

O'Fallon

Maryland Heights

Fairview Heights

Collinsville

Eureka

St. Peters

Glencoe

Festus

Alton

Farmington

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Detroit to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$60	Average$80	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$124	Average$200	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$179	Average$271	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$206	Average$301	FlexibilityNo cancel fee	On-time63%
Delta	Cheapest$215	Average$328	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$340	Average$528	FlexibilityNo cancel fee	On-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$28+ Cheap flights from Detroit Metropolitan Wayne County Airport to St. Louis (DTW - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Detroit to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Lambert-St Louis are usually found in June or May, booked 69 days in advance, depart on a Friday or Thursday and return on a Friday

Cheap flight deals from Detroit to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Detroit to St. Louis

Cheapest flights from Detroit to St. LouisExplore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Explore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to St. Louis that are best for you.

The best insider tips for Detroit Metropolitan Wayne County Airport to St. Louis flights

Cheapflights partnered with top experts to bring you the best recommendations for your Detroit Metropolitan Wayne County Airport to St. Louis trip

Airports

DTW

STL

Our travel experts

Best time to book a flight from Detroit to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Detroit with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to St. Louis

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to St. Louis. Price data was last updated on June 9, 2025.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to St. Louis?

What is the cheapest time of day to fly from DTW to STL?

Find hourly flight availability from Detroit to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to St. Louis

Explore weekly flight availability from Detroit to St. Louis. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 12, 2025.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

Reviews of airlines servicing St. Louis

Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Detroit to St. Louis by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Detroit to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Detroit to St. Louis?

What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to St. Louis round-trip?

What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to St. Louis one-way?

What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to St. Louis?

What are the cheapest flights from Detroit Metropolitan Wayne County Airport to St. Louis?

Can I find deals for flights from Detroit to St. Louis that include hotel bookings?

How can I find direct flights from Detroit to St. Louis?

Can I find deals for business class flights from Detroit to St. Louis?

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to St. Louis?

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Detroit to St. Louis

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Detroit to St. Louis
Explore the most affordable flight options available from Detroit to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.