What’s the top layover airport for flights from Boston to St. Louis?

Orlando (MCO) – chosen by Cheapflights users on 80% of 1-stop itineraries from Boston to St. Louis on Cheapflights.

What’s the cheapest layover airport for flights from Boston to St. Louis?

Orlando (MCO) is the most affordable 1-stop option, with an average round-trip price of $128.

Which airport typically offers the quickest layover for flights from Boston to St. Louis?

Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 06m.

What’s the fastest layover option from Boston to St. Louis?

Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 5h 36m.

How popular is this Boston to St. Louis flight route?

Flights from Boston Logan Intl to Lambert-St Louis have been viewed 45 times in the past calendar month.

How long is the flight from Boston to St. Louis?

Airlines like United Airlines and Southwest fly from Boston to St. Louis in about 3h 05m. The time it takes to get you to your destination can typically vary by up to 2h 29m. The distance between Boston and St. Louis is about 1043 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Boston to St. Louis round-trip?

Cheapflights users have booked flights from Boston to St. Louis round-trip from $83. Other airlines that can offer you cheap pricing are Frontier, from $113, and Delta, from $216. Spirit Airlines is priced at 81% lower than the current average price of a flight leaving 3 months from now.

What are the cheapest airlines to fly from Boston to St. Louis one-way?

The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $107. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from Boston to St. Louis for a low price.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the cheapest flights from Boston to St. Louis?

Looking at all options, your cheapest flight can be booked for $108. While the most popular route (Boston Logan Intl - Lambert-St Louis) can be booked for $209 on average, our data indicates $325 when flying from Boston to St. Louis.

What are the most reliable airlines from Boston to St. Louis?

Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Boston to St. Louis on time: Iberia (96%), Envoy Air (89%), American Airlines (86%).

What are the most popular airlines that fly from Boston to St. Louis?

Consider American Airlines, Delta or Frontier when booking your flight. These represent the most popular airlines when flying from Boston to St. Louis.

What airports do I use to fly from Boston to St. Louis?

If you wish to fly to St. Louis from Boston, then you need to book flights from Boston Logan Intl to Lambert-St Louis. There are 4 flights from Logan Intl (BOS) to Lambert-St Louis (STL) per day to choose from. Flights to St. Louis from Logan Intl are available from 6 different airlines, which means you should have some options if you want to compare airfare deals. 2h 50m is how long a nonstop flight from Boston to Lambert-St Louis typically takes.

Can I find deals for flights from Boston to St. Louis that include hotel bookings?

Yes. In addition to deals on Boston to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Boston to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Boston to St. Louis.

Can I find deals for business class flights from Boston to St. Louis?

Yes. Cheapflights offers flight deals from Boston to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$87+ Flights from Boston to St. Louis

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Boston Logan Intl to Lambert-St Louis are usually found in August or January, booked 25 days in advance, depart on a Wednesday or Thursday and return on a Wednesday

Cheap flight deals from Boston to St. Louis

Round-trip from	$273 (Kiwi.com)
One-way from	$87 (Kiwi.com)
Popular in	April
Cheapest in	August
Average price	$421
Good round-trip deal	$356 or less
Good one-way deal	$170 or less

From Boston Logan Intl to Lambert-St Louis

Search Deals

One-way flight from Boston Logan Intl to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($35 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Price to beat on a round-trip flight from Boston Logan Intl to Lambert-St Louis.

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Price to beat on a one-way flight from Boston Logan Intl to Lambert-St Louis.

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Find flight deals from Boston to St. Louis

Cheapest flights from Boston to St. Louis
Explore the most affordable flight options available from Boston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

Fri 10/178:24 pmBOS - STL

1 stop22h 46mMultiple Airlines

Mon 10/208:21 pmSTL - BOS

2 stops15h 59mMultiple Airlines

Deal found 9/15

$273

Sat 10/188:00 amBOS - STL

1 stop9h 04mAmerican Airlines

Mon 10/207:00 pmSTL - BOS

Nonstop2h 37mAmerican Airlines

Deal found 9/15

$276

Sat 11/112:31 pmBOS - STL

1 stop23h 31mMultiple Airlines

Tue 11/47:45 pmSTL - BOS

2 stops25h 23mMultiple Airlines

Deal found 9/15

$278

Sat 10/2512:31 pmBOS - STL

1 stop22h 31mMultiple Airlines

Sun 11/911:23 amSTL - BOS

1 stop20h 37mMultiple Airlines

Deal found 9/15

$279

Wed 12/34:20 pmBOS - STL

1 stop5h 00mAmerican Airlines

Sat 12/61:59 pmSTL - BOS

1 stop9h 00mAmerican Airlines

Deal found 9/17

$280

Tue 10/72:15 pmBOS - STL

2 stops19h 52mMultiple Airlines

Thu 10/910:57 amSTL - BOS

1 stop12h 02mMultiple Airlines

Deal found 9/15

$284

Tue 10/282:15 pmBOS - STL

2 stops19h 52mMultiple Airlines

Thu 10/3010:57 amSTL - BOS

1 stop12h 02mMultiple Airlines

Deal found 9/15

$285

Tue 11/186:48 amBOS - STL

1 stop9h 14mAmerican Airlines

Sat 11/229:12 amSTL - BOS

1 stop6h 50mAmerican Airlines

Deal found 9/15

$286

Sun 12/79:00 amBOS - STL

1 stop8h 59mAmerican Airlines

Tue 12/911:50 amSTL - BOS

Nonstop2h 40mAmerican Airlines

Deal found 9/14

$287

Thu 10/99:50 amBOS - STL

1 stop25h 47mFrontier

Tue 10/217:52 pmSTL - BOS

2 stops36h 03mFrontier

Deal found 9/16

$288

Tue 10/212:15 pmBOS - STL

2 stops19h 52mMultiple Airlines

Sun 10/2610:57 amSTL - BOS

1 stop23h 19mMultiple Airlines

Deal found 9/15

$290

Best flights from Boston to St. Louis
Discover carefully curated flight deals from Boston to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2025.

Tue 10/79:53 amBOS - STL

1 stop5h 34mUnited Airlines

Wed 10/85:00 amSTL - BOS

1 stop5h 02mUnited Airlines

Deal found 9/15

$297

Wed 12/310:20 amBOS - STL

Nonstop3h 05mSouthwest

Sat 12/68:25 amSTL - BOS

Nonstop2h 30mSouthwest

Deal found 9/17

$333

Tue 10/2112:10 pmBOS - STL

1 stop4h 57mUnited Airlines

Fri 10/2412:25 pmSTL - BOS

1 stop6h 06mUnited Airlines

Deal found 9/14

$329

Tue 10/285:30 amBOS - STL

1 stop6h 55mSouthwest

Thu 10/308:10 pmSTL - BOS

Nonstop2h 30mSouthwest

Deal found 9/16

$343

Wed 10/1511:02 amBOS - STL

1 stop5h 42mUnited Airlines

Thu 10/165:00 amSTL - BOS

1 stop5h 02mUnited Airlines

Deal found 9/15

$353

Thu 10/235:00 amBOS - STL

1 stop4h 55mSouthwest

Mon 10/278:10 pmSTL - BOS

Nonstop2h 30mSouthwest

Deal found 9/16

$359

Sat 11/16:00 amBOS - STL

2 stops9h 25mUnited Airlines

Sat 11/86:43 pmSTL - BOS

1 stop13h 47mUnited Airlines

Deal found 9/17

$371

Sun 12/71:30 pmBOS - STL

Nonstop3h 05mSouthwest

Tue 12/96:10 pmSTL - BOS

Nonstop2h 30mSouthwest

Deal found 9/14

$379

Tue 10/79:53 amBOS - STL

1 stop5h 34mUnited Airlines

Fri 10/1012:25 pmSTL - BOS

1 stop6h 06mUnited Airlines

Deal found 9/14

$379

Mon 12/85:45 amBOS - STL

2 stops7h 50mSouthwest

Thu 12/1110:15 amSTL - BOS

2 stops7h 55mSouthwest

Deal found 9/14

$379

Tue 10/286:00 amBOS - STL

1 stop10h 47mUnited Airlines

Tue 11/46:30 amSTL - BOS

2 stops6h 59mUnited Airlines

Deal found 9/16

$388

Last-minute flights from Boston to St. Louis
Discover last-minute flight deals from Boston to St. Louis. Data last updated September 17, 2025 and is based on user searches.

Thu 10/210:53 amBOS - STL

2 stops23h 13mMultiple Airlines

Thu 10/910:57 amSTL - BOS

1 stop12h 02mMultiple Airlines

Deal found 9/15

$295

Tue 10/72:15 pmBOS - STL

2 stops19h 52mMultiple Airlines

Thu 10/910:57 amSTL - BOS

1 stop12h 02mMultiple Airlines

Deal found 9/15

$284

Thu 10/99:50 amBOS - STL

1 stop25h 47mFrontier

Tue 10/217:52 pmSTL - BOS

2 stops36h 03mFrontier

Deal found 9/16

$288

Fri 10/178:24 pmBOS - STL

1 stop22h 46mMultiple Airlines

Mon 10/208:21 pmSTL - BOS

2 stops15h 59mMultiple Airlines

Deal found 9/15

$273

Sat 10/188:00 amBOS - STL

1 stop9h 04mAmerican Airlines

Mon 10/207:00 pmSTL - BOS

Nonstop2h 37mAmerican Airlines

Deal found 9/15

$276

Mon 10/2012:49 pmBOS - STL

2 stops30h 47mMultiple Airlines

Sat 10/257:15 pmSTL - BOS

1 stop15h 01mMultiple Airlines

Deal found 9/15

$296

Tue 10/212:15 pmBOS - STL

2 stops19h 52mMultiple Airlines

Sun 10/2610:57 amSTL - BOS

1 stop23h 19mMultiple Airlines

Deal found 9/15

$290

Fri 10/248:24 pmBOS - STL

1 stop22h 46mMultiple Airlines

Mon 10/276:05 pmSTL - BOS

1 stop18h 15mMultiple Airlines

Deal found 9/15

$287

Sat 10/2512:31 pmBOS - STL

1 stop22h 31mMultiple Airlines

Sun 11/911:23 amSTL - BOS

1 stop20h 37mMultiple Airlines

Deal found 9/15

$279

Tue 10/282:15 pmBOS - STL

2 stops19h 52mMultiple Airlines

Thu 10/3010:57 amSTL - BOS

1 stop12h 02mMultiple Airlines

Deal found 9/15

$285

One-way flights from Boston to St. Louis
Search for one-way flight options from Boston to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 17, 2025.

Wed 10/156:16 amBOS - STL

1 stop28h 46mSpirit Airlines

Deal found 9/15

$87

Sat 12/65:45 amBOS - STL

1 stop9h 08mSpirit Airlines

Deal found 9/15

$95

Sat 11/16:16 amBOS - STL

1 stop12h 54mSpirit Airlines

Deal found 9/17

$98

Wed 10/156:16 amBOS - STL

2 stops28h 06mMultiple Airlines

Deal found 9/15

$99

Fri 10/319:55 amBOS - STL

1 stop7h 02mFrontier

Deal found 9/15

$101

Wed 10/226:16 amBOS - STL

1 stop28h 46mSpirit Airlines

Deal found 9/14

$102

Sat 11/155:45 amBOS - STL

1 stop30h 16mSpirit Airlines

Deal found 9/14

$107

Tue 10/73:00 pmBOS - STL

2 stops43h 22mMultiple Airlines

Deal found 9/15

$109

Fly from

Fly to

Route

Depart

Return

Price

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Tue 10/7

9:53 am-2:27 pm

1 stop5h 34m

Lambert-St Louis

Wed 10/8

5:00 am-11:02 am

1 stop5h 02m

$297

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Tue 10/21

12:10 pm-4:07 pm

1 stop4h 57m

Lambert-St Louis

Fri 10/24

12:25 pm-7:31 pm

1 stop6h 06m

$329

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Wed 12/3

10:20 am-12:25 pm

Nonstop3h 05m

Lambert-St Louis

Sat 12/6

8:25 am-11:55 am

Nonstop2h 30m

$333

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Tue 10/28

5:30 am-11:25 am

1 stop6h 55m

Lambert-St Louis

Thu 10/30

8:10 pm-11:40 pm

Nonstop2h 30m

$343

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Wed 10/15

11:02 am-3:44 pm

1 stop5h 42m

Lambert-St Louis

Thu 10/16

5:00 am-11:02 am

1 stop5h 02m

$353

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Thu 10/23

5:00 am-8:55 am

1 stop4h 55m

Lambert-St Louis

Mon 10/27

8:10 pm-11:40 pm

Nonstop2h 30m

$359

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Sat 11/1

6:00 am-2:25 pm

2 stops9h 25m

Lambert-St Louis

Sat 11/8

6:43 pm-9:30 am

1 stop13h 47m

$371

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Sun 12/7

1:30 pm-3:35 pm

Nonstop3h 05m

Lambert-St Louis

Tue 12/9

6:10 pm-9:40 pm

Nonstop2h 30m

$379

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Tue 10/7

9:53 am-2:27 pm

1 stop5h 34m

Lambert-St Louis

Fri 10/10

12:25 pm-7:31 pm

1 stop6h 06m

$379

BostonSt. Louis

BOS - STL

BOSSTL

Boston Logan Intl

Mon 12/8

5:45 am-12:35 pm

2 stops7h 50m

Lambert-St Louis

Thu 12/11

10:15 am-7:10 pm

2 stops7h 55m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 21 results

The best insider tips for Boston to St. Louis flights

Cheapflights partnered with top experts to bring you the best recommendations for your Boston to St. Louis trip

Airports

BOS

Use the FlyLogan App to pre-order food and save time at BOS. Most restaurants participate, making it a convenient option.

STL

Take the MetroLink light rail from STL to downtown St. Louis. It's affordable and takes about 40 minutes, ideal for light luggage.

Our travel experts

Paul Rubio

Expert on BOS

Taryn White

Expert on STL

Best time to book a flight from Boston to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Boston with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Boston to St. Louis

Prices

How far ahead should I book a flight from Boston to St. Louis?

To ensure you get the cheapest price possible for a flight from Boston to St. Louis, you should look to book at least 25 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Boston to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Boston to St. Louis (average of $311). Flying from Boston to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BOS to STL?

It’s typically best to fly out from Boston to St. Louis in the evening. Doing so could potentially save you 5% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Boston to St. Louis?

Travelers seeking maximum savings on their Boston to St. Louis flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Boston to St. Louis, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southwest

8.0

Very good

4,242 reviews

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Delta

8.0

Very good

7,961 reviews

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Spirit Airlines

6.3

Okay

8,023 reviews

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Frontier

5.8

Fair

3,173 reviews

Southwest

8.0

Very good

4,242 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

What airports do I use to fly from Boston to St. Louis?
If you wish to fly to St. Louis from Boston, then you need to book flights from Boston Logan Intl to Lambert-St Louis. There are 4 flights from Logan Intl (BOS) to Lambert-St Louis (STL) per day to choose from. Flights to St. Louis from Logan Intl are available from 6 different airlines, which means you should have some options if you want to compare airfare deals. 2h 50m is how long a nonstop flight from Boston to Lambert-St Louis typically takes.
How popular is this Boston to St. Louis flight route?
Flights from Boston Logan Intl to Lambert-St Louis have been viewed 45 times in the past calendar month.
How long is the flight from Boston to St. Louis?
Airlines like United Airlines and Southwest fly from Boston to St. Louis in about 3h 05m. The time it takes to get you to your destination can typically vary by up to 2h 29m. The distance between Boston and St. Louis is about 1043 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Boston to St. Louis round-trip?
Cheapflights users have booked flights from Boston to St. Louis round-trip from $83. Other airlines that can offer you cheap pricing are Frontier, from $113, and Delta, from $216. Spirit Airlines is priced at 81% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from Boston to St. Louis one-way?
The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $107. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from Boston to St. Louis for a low price.
What are the most reliable airlines from Boston to St. Louis?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Boston to St. Louis on time: Iberia (96%), Envoy Air (89%), American Airlines (86%).
What are the cheapest flights from Boston to St. Louis?
Looking at all options, your cheapest flight can be booked for $108. While the most popular route (Boston Logan Intl - Lambert-St Louis) can be booked for $209 on average, our data indicates $325 when flying from Boston to St. Louis.
Can I find deals for flights from Boston to St. Louis that include hotel bookings?
Yes. In addition to deals on Boston to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Boston to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Boston to St. Louis.
Can I find deals for business class flights from Boston to St. Louis?
Yes. Cheapflights offers flight deals from Boston to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Boston to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Boston to St. Louis (average of $311). Flying from Boston to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Edwardsville

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Fairview Heights

Maryland Heights

Collinsville

Eureka

Glencoe

St. Peters

Chesterfield

Alton

Farmington

Festus

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Top 6 airlines flying from Boston to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$83	Average$186	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$113	Average$213	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$216	Average$294	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$257	Average$412	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$297	Average$459	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$323	Average$462	FlexibilityNo cancel fee	On-time63%

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$87+ Cheap flights from Boston to St. Louis (BOS - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Boston to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Boston Logan Intl to Lambert-St Louis are usually found in August or January, booked 25 days in advance, depart on a Wednesday or Thursday and return on a Wednesday

Cheap flight deals from Boston to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Boston to St. Louis

Cheapest flights from Boston to St. LouisExplore the most affordable flight options available from Boston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

Explore the most affordable flight options available from Boston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Boston to St. Louis that are best for you.

The best insider tips for Boston to St. Louis flights

Cheapflights partnered with top experts to bring you the best recommendations for your Boston to St. Louis trip

Airports

BOS

STL

Our travel experts

Best time to book a flight from Boston to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Boston with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Boston to St. Louis

How far ahead should I book a flight from Boston to St. Louis?

What is the cheapest month to book a flight from Boston to St. Louis?

What is the cheapest time of day to fly from BOS to STL?

What is the cheapest day to fly from Boston to St. Louis?

What’s the top layover airport for flights from Boston to St. Louis?

What’s the fastest layover option from Boston to St. Louis?

What’s the fastest layover option from Boston to St. Louis?

Which airport typically offers the quickest layover for flights from Boston to St. Louis?

Reviews of airlines servicing St. Louis

Read through reviews of airlines operating flights from Boston to St. Louis, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Boston to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Boston to St. Louis?

How popular is this Boston to St. Louis flight route?

How long is the flight from Boston to St. Louis?

What are the cheapest airlines flying from Boston to St. Louis round-trip?

What are the cheapest airlines to fly from Boston to St. Louis one-way?

What are the most reliable airlines from Boston to St. Louis?

What are the cheapest flights from Boston to St. Louis?

Can I find deals for flights from Boston to St. Louis that include hotel bookings?

How can I find direct flights from Boston to St. Louis?

Can I find deals for business class flights from Boston to St. Louis?

What is the cheapest month to book a flight from Boston to St. Louis?

Traveling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Boston to St. Louis

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Top 6 airlines flying from Boston to St. Louis

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Cheapest flights from Boston to St. Louis
Explore the most affordable flight options available from Boston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.