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$281+ Cheap flights from Missouri to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
jul. 8 — jul. 151
mar. 7/8
mar. 7/15
1 adult, Economy
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Cheap flight deals from Missouri to Spain

Keep the following information in mind while searching for Missouri to Spain flight deals. Data was last updated julio 3, 2025.

Round-trip from

$472
(Air Canada)

One-way from

$281
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$1,322
From Missouri to Spain
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One-way flight from Missouri to Spain
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Highest demand for flights based on searches. 31% potential increase in price ($437 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($49 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Missouri to Spain

Cheapest flights from Missouri to Spain
Explore the most affordable flight options available from Missouri to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

This Air Canada deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/217:30 amMCI - MAD
2 stops40h 10mAir Canada
mar. 9/3012:30 pmMAD - MCI
2 stops34h 26mAir Canada
Deal found 7/1$472
This Travelocity deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/216:00 amMCI - MAD
1 stop24h 25mBritish Airways
mar. 9/304:40 pmMAD - MCI
1 stop29h 31mBritish Airways
Deal found 7/1$488
This Iberia deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/236:26 pmMCI - MAD
1 stop12h 54mIberia
mar. 9/309:50 pmMAD - MCI
2 stops32h 17mIberia
Deal found 7/1$502
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/108:00 amMCI - MAD
2 stops39h 40mUnited Airlines
jue. 12/181:35 pmMAD - MCI
2 stops36h 56mUnited Airlines
Deal found 7/1$515
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/206:00 pmMCI - MAD
1 stop32h 35mDelta
dom. 9/2810:05 amMAD - MCI
1 stop14h 32mDelta
Deal found 7/1$538
This CheapOair deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/11:30 pmSTL - BCN
1 stop11h 20mAir Canada
vie. 10/1012:10 pmBCN - STL
2 stops34h 34mAir Canada
Deal found 7/2$555
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/61:30 pmSTL - MAD
1 stop10h 10mUnited Airlines
mar. 10/2112:45 pmMAD - STL
2 stops32h 42mUnited Airlines
Deal found 7/3$560
This Expedia deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/17:56 pmMCI - MAD
2 stops16h 44mMultiple Airlines
lun. 9/229:50 pmMAD - MCI
2 stops29h 57mMultiple Airlines
Deal found 6/30$561
This Air Canada deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/612:25 pmSTL - MAD
2 stops35h 15mAir Canada
mié. 10/2212:45 pmMAD - STL
2 stops32h 42mAir Canada
Deal found 7/1$564
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/11:30 pmSTL - BCN
1 stop11h 20mUnited Airlines
vie. 10/1012:10 pmBCN - STL
1 stop14h 47mUnited Airlines
Deal found 7/3$568
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/2211:25 amSGF - MAD
2 stops13h 40mUnited Airlines
mié. 11/121:35 pmMAD - SGF
2 stops35h 11mUnited Airlines
Deal found 7/3$569
This Cheapflightsfares deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/212:19 pmSGF - MAD
1 stop17h 01mIberia
lun. 11/1712:55 amMAD - SGF
1 stop14h 42mIberia
Deal found 7/3$581

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
Use the filters below to find and compare flights from Missouri to Spain that are best for you.

Fly from

Missouri

Fly to

Spain

Route

Depart

Return

Price

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

dom. 9/21

7:30 am-6:40 am

2 stops40h 10m

Madrid Barajas

mar. 9/30

12:30 pm-3:56 pm

2 stops34h 26m

$472

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

dom. 9/21

6:00 am-1:25 pm

1 stop24h 25m

Madrid Barajas

mar. 9/30

4:40 pm-3:11 pm

1 stop29h 31m

$488

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

mar. 9/23

6:26 pm-2:20 pm

1 stop12h 54m

Madrid Barajas

mar. 9/30

9:50 pm-11:07 pm

2 stops32h 17m

$502

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

dom. 8/10

8:00 am-6:40 am

2 stops39h 40m

Madrid Barajas

jue. 12/18

1:35 pm-7:31 pm

2 stops36h 56m

$515

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

sáb. 9/20

6:00 pm-9:35 am

1 stop32h 35m

Madrid Barajas

dom. 9/28

10:05 am-5:37 pm

1 stop14h 32m

$538

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

mié. 10/1

1:30 pm-7:50 am

1 stop11h 20m

Barcelona-El Prat

vie. 10/10

12:10 pm-3:44 pm

2 stops34h 34m

$555

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

lun. 10/6

1:30 pm-6:40 am

1 stop10h 10m

Madrid Barajas

mar. 10/21

12:45 pm-2:27 pm

2 stops32h 42m

$560

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

lun. 9/1

7:56 pm-7:40 pm

2 stops16h 44m

Madrid Barajas

lun. 9/22

9:50 pm-8:47 pm

2 stops29h 57m

$561

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

lun. 10/6

12:25 pm-6:40 am

2 stops35h 15m

Madrid Barajas

mié. 10/22

12:45 pm-2:27 pm

2 stops32h 42m

$564

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

mié. 10/1

1:30 pm-7:50 am

1 stop11h 20m

Barcelona-El Prat

vie. 10/10

12:10 pm-7:57 pm

1 stop14h 47m

$568

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Spain

What is the cheapest month to book a flight from Missouri to Spain?

Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ES?

Find hourly flight availability from Missouri to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Spain as you normally would.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated julio 3, 2025.
Read through reviews of airlines operating flights from Missouri to Spain, such as Delta, KLM, and Finnair. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,367 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Finnair
7.6
Good
1,306 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air France
7.5
Good
1,465 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
SWISS
7.5
Good
1,654 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Spain one-way?

    The cheapest airline one-way is Air Canada, with whom users have recently found tickets for as low as $418. However, be on the lookout for offers from Virgin Atlantic and Delta, as they are both options that can get you from Missouri to Spain for a low price.

  • Can I find deals for flights from Missouri to Spain that include hotel bookings?

    Yes. In addition to deals on Missouri to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Spain.

  • Can I find deals for business class flights from Missouri to Spain?

    Yes. Cheapflights offers flight deals from Missouri to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Spain?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Spain (average of $543). Flying from Missouri to Spain in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Spain

Discover the top 9 airlines that operate flights from Missouri to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$468Average$769FlexibilityNo cancel feeOn-time75%
DeltaCheapest$492Average$958FlexibilityNo cancel feeOn-timeN/A
LufthansaCheapest$527Average$1,105FlexibilityNo cancel feeOn-time76%
American AirlinesCheapest$534Average$1,052FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$542Average$1,023FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$545Average$911FlexibilityNo cancel feeOn-time70%
IberiaCheapest$576Average$1,018FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$629Average$1,094FlexibilityNo cancel feeOn-time67%
Air FranceCheapest$657Average$843FlexibilityNo cancel feeOn-time77%

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