Consider American Airlines, Air France or British Airways when booking your flight. These represent the most popular airlines when flying from Birmingham, USA to Spain.
The most popular route from Birmingham, USA to Spain is Birmingham - Madrid Barajas. You may also consider Birmingham - Malaga or Birmingham - Barcelona-El Prat.
The cheapest flight price from Birmingham, USA to Spain is $488. On average you can expect to pay $832. The most popular route, (Birmingham - Madrid Barajas), can usually be booked for $492.