How long is the flight from South Carolina to South Dakota?

A quick flight from South Carolina to South Dakota can take about 5h 17m. Delta provides one of the quickest options available for as low as $251. There are 1019 mi between South Carolina and South Dakota. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines to fly from South Carolina to South Dakota one-way?

One-way options have recently been found by users for as low as $126 on Delta. Other airlines that offer cheap prices include United Airlines from $135 and American Airlines from $256 one-way.

In terms of precipitation, rainfall in South Dakota ranges from 0.6 - 3.9 inches per month. June is typically the wettest month, when rainfall can reach 3.9 in. January is typically the driest time to visit South Dakota when rainfall is around 0.6 in.

If weather is an important factor for your trip to South Dakota, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 15.8 F).

Can I find deals for flights from South Carolina to South Dakota that include hotel bookings?

Yes. In addition to deals on South Carolina to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to South Dakota?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to South Dakota.

Can I find deals for business class flights from South Carolina to South Dakota?

Yes. Cheapflights offers flight deals from South Carolina to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$103+ Flights from South Carolina to South Dakota

Q: How much does it cost to fly round-trip from South Carolina to South Dakota?

Airfare is below average for this route at the moment. South Carolina to South Dakota flights typically cost between $324 and $513 in November. The cheapest round-trip price found within the last 3 days was $289 on United Airlines (Nov 6-Nov 10).

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Find cheap flights from South Carolina to South Dakota with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheap flight deals from South Carolina to South Dakota

Round-trip from	$251 (Delta)
One-way from	$103 (Kiwi.com)

From South Carolina to South Dakota

Search Deals

One-way flight from South Carolina to South Dakota

Search Deals

Find flight deals from South Carolina to South Dakota

Cheapest flights from South Carolina to South Dakota
Explore the most affordable flight options available from South Carolina to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

Wed 12/35:00 pmCLT - FSD

1 stop7h 12mDelta

Sat 12/68:01 amFSD - CLT

1 stop7h 24mDelta

Deal found 10/21

$251

Fri 12/123:21 pmCHS - RAP

1 stop7h 55mAmerican Airlines

Mon 12/151:47 pmRAP - CHS

1 stop6h 25mAmerican Airlines

Deal found 10/22

$269

Thu 11/64:11 pmCHS - FSD

1 stop8h 33mUnited Airlines

Mon 11/106:00 amFSD - CHS

1 stop8h 06mUnited Airlines

Deal found 10/22

$289

Wed 11/54:17 pmGSP - RAP

1 stop7h 42mUnited Airlines

Wed 11/125:15 amRAP - GSP

1 stop7h 44mUnited Airlines

Deal found 10/21

$294

Fri 11/215:23 amCLT - FSD

1 stop8h 13mAmerican Airlines

Mon 11/245:31 pmFSD - CLT

1 stop6h 16mAmerican Airlines

Deal found 10/21

$299

Wed 11/126:00 amGSP - FSD

1 stop5h 28mAmerican Airlines

Sun 11/165:30 amFSD - GSP

1 stop4h 28mAmerican Airlines

Deal found 10/21

$305

Thu 11/64:17 pmGSP - RAP

1 stop6h 09mUnited Airlines

Mon 11/105:15 amRAP - GSP

1 stop7h 44mUnited Airlines

Deal found 10/22

$319

Sat 12/612:44 pmCLT - FSD

2 stops11h 30mDelta

Sat 12/133:00 pmFSD - CLT

2 stops7h 39mDelta

Deal found 10/21

$320

Sat 10/252:26 pmCHS - FSD

1 stop7h 50mAmerican Airlines

Sat 11/810:59 amFSD - CHS

1 stop6h 08mAmerican Airlines

Deal found 10/22

$324

Wed 11/510:00 amGSP - RAP

2 stops10h 43mUnited Airlines

Mon 11/107:10 amRAP - GSP

1 stop5h 49mUnited Airlines

Deal found 10/22

$324

Sat 10/255:05 pmCLT - FSD

1 stop6h 51mDelta

Fri 10/315:20 amFSD - CLT

1 stop4h 36mDelta

Deal found 10/21

$329

Fri 10/314:14 pmCHS - FSD

1 stop7h 42mDelta

Mon 11/35:30 amFSD - CHS

1 stop5h 16mDelta

Deal found 10/22

$336

Best flights from South Carolina to South Dakota
Discover carefully curated flight deals from South Carolina to South Dakota that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 23, 2025.

Sat 12/66:03 amCLT - FSD

1 stop5h 17mDelta

Sat 12/135:14 amFSD - CLT

1 stop4h 39mDelta

Deal found 10/21

$251

Fri 12/123:21 pmCHS - RAP

1 stop7h 55mAmerican Airlines

Mon 12/151:47 pmRAP - CHS

2 stops8h 59mAmerican Airlines

Deal found 10/22

$274

Thu 11/64:11 pmCHS - FSD

1 stop8h 33mUnited Airlines

Mon 11/108:00 amFSD - CHS

2 stops10h 00mUnited Airlines

Deal found 10/22

$294

Thu 11/138:53 pmCHS - FSD

1 stop14h 27mMultiple Airlines

Sun 11/169:21 amFSD - CHS

2 stops30h 45mMultiple Airlines

Deal found 10/22

$349

Wed 12/35:00 pmCLT - FSD

1 stop7h 12mDelta

Sat 12/68:01 amFSD - CLT

1 stop7h 24mDelta

Deal found 10/21

$251

Tue 2/179:07 amSAV - RAP

2 stops13h 04mAmerican Airlines

Sat 2/2112:30 pmRAP - SAV

1 stop7h 16mAmerican Airlines

Deal found 10/23

$274

Wed 11/54:17 pmGSP - RAP

1 stop7h 42mUnited Airlines

Wed 11/125:15 amRAP - GSP

1 stop7h 44mUnited Airlines

Deal found 10/21

$294

Tue 2/242:59 pmCAE - RAP

2 stops9h 15mDelta

Sat 2/2810:40 amRAP - CAE

2 stops8h 04mDelta

Deal found 10/20

$279

Tue 11/114:17 pmGSP - RAP

1 stop7h 42mUnited Airlines

Sat 11/155:15 amRAP - GSP

2 stops9h 38mUnited Airlines

Deal found 10/22

$299

Fri 11/215:23 amCLT - FSD

1 stop8h 13mAmerican Airlines

Mon 11/245:31 pmFSD - CLT

1 stop6h 16mAmerican Airlines

Deal found 10/21

$299

Sat 1/1712:00 pmGSP - RAP

2 stops12h 14mDelta

Sat 1/3110:40 amRAP - GSP

2 stops10h 56mDelta

Deal found 10/21

$279

Wed 11/126:00 amGSP - FSD

1 stop5h 28mAmerican Airlines

Sun 11/165:30 amFSD - GSP

1 stop4h 28mAmerican Airlines

Deal found 10/21

$305

Thu 11/205:55 pmCLT - FSD

1 stop15h 48mMultiple Airlines

Fri 11/284:41 pmFSD - CLT

2 stops25h 18mMultiple Airlines

Deal found 10/22

$385

Fri 11/74:17 pmGSP - RAP

1 stop6h 09mUnited Airlines

Mon 11/105:15 amRAP - GSP

1 stop7h 44mUnited Airlines

Deal found 10/22

$319

Tue 11/117:27 amGSP - RAP

2 stops10h 18mDelta

Sat 11/1511:07 amRAP - GSP

2 stops8h 10mDelta

Deal found 10/22

$304

Wed 11/127:59 pmCLT - FSD

2 stops18h 29mMultiple Airlines

Sun 11/162:18 pmFSD - CLT

1 stop25h 59mMultiple Airlines

Deal found 10/22

$385

Wed 11/54:17 pmGSP - RAP

1 stop7h 42mUnited Airlines

Mon 11/105:15 amRAP - GSP

1 stop7h 44mUnited Airlines

Deal found 10/22

$319

Thu 11/64:24 pmGSP - RAP

1 stop6h 53mAmerican Airlines

Mon 11/101:42 pmRAP - GSP

1 stop8h 33mAmerican Airlines

Deal found 10/22

$319

Sat 2/217:15 amGSP - FSD

2 stops9h 18mDelta

Tue 2/241:20 pmFSD - GSP

2 stops7h 45mDelta

Deal found 10/20

$315

Thu 11/64:17 pmGSP - RAP

1 stop6h 09mUnited Airlines

Mon 11/105:15 amRAP - GSP

1 stop7h 44mUnited Airlines

Deal found 10/22

$319

Sat 2/217:24 amSAV - RAP

1 stop6h 07mAmerican Airlines

Tue 2/2412:30 pmRAP - SAV

1 stop7h 16mAmerican Airlines

Deal found 10/20

$349

Sat 2/217:00 amSAV - RAP

2 stops10h 14mDelta

Tue 2/246:20 amRAP - SAV

1 stop5h 51mDelta

Deal found 10/21

$334

Sat 2/216:55 amSAV - RAP

2 stops13h 59mUnited Airlines

Tue 2/247:00 amRAP - SAV

2 stops10h 23mUnited Airlines

Deal found 10/20

$359

Sat 2/218:05 amGSP - FSD

1 stop7h 45mAmerican Airlines

Tue 2/241:30 pmFSD - GSP

1 stop7h 11mAmerican Airlines

Deal found 10/21

$360

Fri 10/314:14 pmCHS - FSD

1 stop7h 42mDelta

Mon 11/35:30 amFSD - CHS

1 stop5h 16mDelta

Deal found 10/21

$336

Wed 11/56:40 amCLT - FSD

1 stop5h 02mUnited Airlines

Tue 11/111:47 pmFSD - CLT

1 stop8h 06mUnited Airlines

Deal found 10/22

$369

Fri 11/217:32 amCHS - FSD

1 stop6h 41mAmerican Airlines

Fri 11/2810:59 amFSD - CHS

1 stop6h 08mAmerican Airlines

Deal found 10/22

$371

Wed 12/35:00 pmCLT - RAP

1 stop7h 46mDelta

Fri 12/52:51 pmRAP - CLT

1 stop6h 32mDelta

Deal found 10/21

$376

Fri 11/74:38 pmCHS - FSD

1 stop6h 08mUnited Airlines

Tue 11/118:00 amFSD - CHS

1 stop4h 55mUnited Airlines

Deal found 10/20

$384

Thu 11/201:01 pmCLT - FSD

1 stop6h 44mAmerican Airlines

Fri 11/285:11 pmFSD - CLT

1 stop6h 07mAmerican Airlines

Deal found 10/21

$400

Last-minute flights from South Carolina to South Dakota
Discover last-minute flight deals from South Carolina to South Dakota. Data last updated October 23, 2025 and is based on user searches.

Sat 10/252:26 pmCHS - FSD

1 stop7h 50mAmerican Airlines

Sat 11/810:59 amFSD - CHS

1 stop6h 08mAmerican Airlines

Deal found 10/22

$324

Sat 10/255:05 pmCLT - FSD

1 stop6h 51mDelta

Fri 10/315:20 amFSD - CLT

1 stop4h 36mDelta

Deal found 10/21

$329

Fri 10/314:14 pmCHS - FSD

1 stop7h 42mDelta

Mon 11/35:30 amFSD - CHS

1 stop5h 16mDelta

Deal found 10/22

$336

Wed 11/54:17 pmGSP - RAP

1 stop7h 42mUnited Airlines

Wed 11/125:15 amRAP - GSP

1 stop7h 44mUnited Airlines

Deal found 10/21

$294

Wed 11/510:00 amGSP - RAP

2 stops10h 43mUnited Airlines

Mon 11/107:10 amRAP - GSP

1 stop5h 49mUnited Airlines

Deal found 10/22

$324

Wed 11/56:40 amCLT - FSD

1 stop5h 02mUnited Airlines

Tue 11/111:47 pmFSD - CLT

1 stop8h 06mUnited Airlines

Deal found 10/22

$369

Thu 11/64:11 pmCHS - FSD

1 stop8h 33mUnited Airlines

Mon 11/106:00 amFSD - CHS

1 stop8h 06mUnited Airlines

Deal found 10/22

$289

Thu 11/64:17 pmGSP - RAP

1 stop6h 09mUnited Airlines

Mon 11/105:15 amRAP - GSP

1 stop7h 44mUnited Airlines

Deal found 10/22

$319

Sun 11/96:40 amCLT - FSD

1 stop5h 02mUnited Airlines

Wed 11/263:15 pmFSD - CLT

1 stop5h 05mUnited Airlines

Deal found 10/23

$368

Wed 11/126:00 amGSP - FSD

1 stop5h 28mAmerican Airlines

Sun 11/165:30 amFSD - GSP

1 stop4h 28mAmerican Airlines

Deal found 10/21

$305

Thu 11/138:53 pmCHS - FSD

1 stop14h 27mMultiple Airlines

Sun 11/169:21 amFSD - CHS

2 stops30h 45mMultiple Airlines

Deal found 10/22

$349

Fri 11/215:23 amCLT - FSD

1 stop8h 13mAmerican Airlines

Mon 11/245:31 pmFSD - CLT

1 stop6h 16mAmerican Airlines

Deal found 10/21

$299

One-way flights from South Carolina to South Dakota
Search for one-way flight options from South Carolina to South Dakota. Find affordable one-way fares based on user searches. Data last updated October 23, 2025.

Thu 1/812:17 pmCLT - FSD

1 stop8h 05mFrontier

Deal found 10/22

$103

Thu 1/1512:17 pmCLT - FSD

1 stop8h 06mFrontier

Deal found 10/22

$113

Mon 1/129:49 amCLT - FSD

1 stop9h 22mMultiple Airlines

Deal found 10/22

$114

Tue 1/64:55 pmCLT - FSD

1 stop7h 03mDelta

Deal found 10/22

$126

Thu 1/153:12 pmCLT - FSD

2 stops19h 45mMultiple Airlines

Deal found 10/22

$132

Thu 12/256:45 pmCLT - FSD

1 stop5h 23mDelta

Deal found 10/22

$135

Wed 12/316:00 amCLT - FSD

2 stops9h 27mUnited Airlines

Deal found 10/22

$140

Thu 12/189:38 pmCLT - FSD

1 stop12h 33mMultiple Airlines

Deal found 10/22

$142

Sat 11/226:00 pmCLT - FSD

1 stop6h 59mAmerican Airlines

Deal found 10/21

$160

Mon 11/243:00 pmCLT - RAP

2 stops20h 43mMultiple Airlines

Deal found 10/23

$164

Wed 12/310:00 amSAV - RAP

2 stops37h 29mMultiple Airlines

Deal found 10/22

$166

Sat 1/108:46 pmCLT - FSD

3 stops38h 11mMultiple Airlines

Deal found 10/22

$170

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to South Dakota that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteSioux Falls

CLT - FSD

CLTFSD

Charlotte Douglas

Sat 12/6

6:03 am-10:20 am

1 stop5h 17m

Sioux Falls Joe Foss Field

Sat 12/13

5:14 am-10:53 am

1 stop4h 39m

$251

CharlotteSioux Falls

CLT - FSD

CLTFSD

Charlotte Douglas

Wed 12/3

5:00 pm-11:12 pm

1 stop7h 12m

Sioux Falls Joe Foss Field

Sat 12/6

8:01 am-4:25 pm

1 stop7h 24m

$251

CharlestonRapid City

CHS - RAP

CHSRAP

Charleston

Fri 12/12

3:21 pm-9:16 pm

1 stop7h 55m

Rapid City

Mon 12/15

1:47 pm-12:46 am

2 stops8h 59m

$274

SavannahRapid City

SAV - RAP

SAVRAP

Savannah/Hilton Head

Tue 2/17

9:07 am-8:11 pm

2 stops13h 04m

Rapid City

Sat 2/21

12:30 pm-9:46 pm

1 stop7h 16m

$274

ColumbiaRapid City

CAE - RAP

CAERAP

Columbia Metropolitan

Tue 2/24

2:59 pm-10:14 pm

2 stops9h 15m

Rapid City

Sat 2/28

10:40 am-8:44 pm

2 stops8h 04m

$279

GreenvilleRapid City

GSP - RAP

GSPRAP

Greenville

Sat 1/17

12:00 pm-10:14 pm

2 stops12h 14m

Rapid City

Sat 1/31

10:40 am-11:36 pm

2 stops10h 56m

$279

CharlestonSioux Falls

CHS - FSD

CHSFSD

Charleston

Thu 11/6

4:11 pm-11:44 pm

1 stop8h 33m

Sioux Falls Joe Foss Field

Mon 11/10

8:00 am-7:00 pm

2 stops10h 00m

$294

GreenvilleRapid City

GSP - RAP

GSPRAP

Greenville

Wed 11/5

4:17 pm-9:59 pm

1 stop7h 42m

Rapid City

Wed 11/12

5:15 am-2:59 pm

1 stop7h 44m

$294

GreenvilleRapid City

GSP - RAP

GSPRAP

Greenville

Tue 11/11

4:17 pm-9:59 pm

1 stop7h 42m

Rapid City

Sat 11/15

5:15 am-4:53 pm

2 stops9h 38m

$299

CharlotteSioux Falls

CLT - FSD

CLTFSD

Charlotte Douglas

Fri 11/21

5:23 am-12:36 pm

1 stop8h 13m

Sioux Falls Joe Foss Field

Mon 11/24

5:31 pm-12:47 am

1 stop6h 16m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/22

Showing 1-10 of 60 results

...

Best time to book a flight from South Carolina to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to South Dakota

What is the cheapest month to book a flight from South Carolina to South Dakota?

Currently, June is the cheapest month in which you can book a flight from South Carolina to South Dakota (average of $179). Flying from South Carolina to South Dakota in February is currently the most expensive (average of $674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SD?

A simple way to save on the total cost of your ticket is to fly from South Carolina to South Dakota in the afternoon. If you’re flexible enough to do this you can expect to save up to 27% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from South Carolina to South Dakota?

Travelers seeking maximum savings on their South Carolina to South Dakota flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from South Carolina to South Dakota?

Reviews of airlines servicing South Dakota

Read through reviews of airlines operating flights from South Carolina to South Dakota, such as Delta, United Airlines, and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

7,982 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Delta

7.9

Good

7,982 reviews

Delta

7.9

Good

7,982 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

United Airlines

7.4

Good

8,995 reviews

Delta

7.9

Good

7,982 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

American Airlines

7.2

Good

11,032 reviews

Delta

7.9

Good

7,982 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

Related info for your journey

How long is the flight from South Carolina to South Dakota?
A quick flight from South Carolina to South Dakota can take about 5h 17m. Delta provides one of the quickest options available for as low as $251. There are 1019 mi between South Carolina and South Dakota. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines to fly from South Carolina to South Dakota one-way?
One-way options have recently been found by users for as low as $126 on Delta. Other airlines that offer cheap prices include United Airlines from $135 and American Airlines from $256 one-way.
Can I find deals for flights from South Carolina to South Dakota that include hotel bookings?
Yes. In addition to deals on South Carolina to South Dakota flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to South Dakota?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to South Dakota.
Can I find deals for business class flights from South Carolina to South Dakota?
Yes. Cheapflights offers flight deals from South Carolina to South Dakota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from South Carolina to South Dakota?
Currently, June is the cheapest month in which you can book a flight from South Carolina to South Dakota (average of $179). Flying from South Carolina to South Dakota in February is currently the most expensive (average of $674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from South Carolina to South Dakota

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$249	Average$388	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$250	Average$498	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$258	Average$451	FlexibilityNo cancel fee	On-time69%

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$103+ Cheap flights from South Carolina to South Dakota

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from South Carolina to South Dakota with Cheapflights

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Cheap flight deals from South Carolina to South Dakota

Keep the following information in mind while searching for South Carolina to South Dakota flight deals. Data was last updated October 23, 2025.

Round-trip from

One-way from

Find flight deals from South Carolina to South Dakota

Cheapest flights from South Carolina to South DakotaExplore the most affordable flight options available from South Carolina to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

Explore the most affordable flight options available from South Carolina to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to South Dakota that are best for you.

Best time to book a flight from South Carolina to South Dakota

Have a flexible travel schedule? Discover the best time to fly to South Dakota from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to South Dakota

What is the cheapest month to book a flight from South Carolina to South Dakota?

What is the cheapest time of day to fly from SC to SD?

Find hourly flight availability from South Carolina to South Dakota. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 23, 2025.

What is the cheapest day to fly from South Carolina to South Dakota?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to South Dakota. Price data was last updated on December 16, 2024.

How much does it cost to fly round-trip from South Carolina to South Dakota?

Reviews of airlines servicing South Dakota

Related info for your journey

Find useful and relevant information for your journey from South Carolina to South Dakota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from South Carolina to South Dakota?

What are the cheapest airlines to fly from South Carolina to South Dakota one-way?

Can I find deals for flights from South Carolina to South Dakota that include hotel bookings?

How can I find direct flights from South Carolina to South Dakota?

Can I find deals for business class flights from South Carolina to South Dakota?

What is the cheapest month to book a flight from South Carolina to South Dakota?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to South Dakota

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from South Carolina to South Dakota

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Cheapest flights from South Carolina to South Dakota
Explore the most affordable flight options available from South Carolina to South Dakota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.