$401+ Cheap flights from Tyler (TYR) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYR — CHS
Nov 29 — Dec 61
1 adult, Economy
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1. Tell us where you want to go
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Best flights from Tyler to South CarolinaDiscover carefully curated flight deals from Tyler to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.
Discover carefully curated flight deals from Tyler to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2510:29 amTYR - GSP
1 stop3h 58mAmerican Airlines
Sat 3/287:53 pmGSP - TYR
1 stop4h 37mAmerican Airlines
Deal found 10/27![American Airlines logo]()
$503
Cheap flight deals from Tyler to South Carolina
Keep the following information in mind while searching for Tyler to South Carolina flight deals. Data was last updated October 30, 2025.
Most accurate provider | Expedia 2 stars |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $503 (American Airlines) |
One-way from | $401 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Tyler to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Tyler to South Carolina that are best for you.
Fly from
Tyler
Fly to
South Carolina
Route
Depart
Return
Price
TylerGreenville
TYR - GSP
TYRGSP
Tyler Pounds Field
Wed 3/25
10:29 am-3:27 pm
1 stop3h 58m
Greenville
Sat 3/28
7:53 pm-11:30 pm
1 stop4h 37m
$503
TylerGreenville
TYR - GSP
TYRGSP
Tyler Pounds Field
Mon 11/17
10:17 am-3:33 pm
1 stop4h 16m
$401
Best time to book a flight from Tyler to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Tyler with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Tyler to South Carolina
What is the cheapest month to book a flight from Tyler to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Tyler to South Carolina (average of $179). Flying from Tyler to South Carolina in October is currently the most expensive (average of $291). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.