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South Carolina

$48+ Cheap flights from Tampa (TPA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/3. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — CHS
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
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Cheap flight deals from Tampa to South Carolina

Cheapest flights from Tampa to South Carolina
Explore the most affordable flight options available from Tampa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Flightnetwork deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:32 am
TPA
-
GSP
Nonstop1h 40m
Breeze Airways
Thu 5/72:18 pm
GSP
-
TPA
Nonstop1h 38m
Breeze Airways
Deal found 3/16$112
This Mytrip deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:32 am
TPA
-
GSP
Nonstop1h 40m
Breeze Airways
Sun 4/192:12 pm
GSP
-
TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/16$116
This Mytrip deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:32 am
TPA
-
GSP
Nonstop1h 40m
Breeze Airways
Thu 4/232:12 pm
GSP
-
TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/16$117
This Mytrip deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:27 pm
TPA
-
GSP
Nonstop1h 40m
Breeze Airways
Mon 4/204:07 pm
GSP
-
TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/14$121
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:05 am
TPA
-
GSP
Nonstop1h 41m
Breeze Airways
Mon 6/2210:26 am
GSP
-
TPA
Nonstop1h 38m
Breeze Airways
Deal found 3/16$125
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
-
MYR
Nonstop1h 38m
Breeze Airways
Sun 5/36:59 pm
MYR
-
TPA
Nonstop1h 42m
Breeze Airways
Deal found 3/13$128
This Booking.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:58 am
TPA
-
MYR
Nonstop1h 41m
Breeze Airways
Mon 5/116:14 pm
MYR
-
TPA
Nonstop1h 37m
Breeze Airways
Deal found 3/15$130
This Mytrip deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:05 am
TPA
-
MYR
Nonstop1h 38m
Breeze Airways
Fri 5/16:55 pm
MYR
-
TPA
Nonstop1h 42m
Breeze Airways
Deal found 3/14$132
This Breeze Airways deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:27 pm
TPA
-
GSP
Nonstop1h 40m
Breeze Airways
Mon 5/44:07 pm
GSP
-
TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/14$133
This Cheapflightsfares deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:46 pm
TPA
-
CLT
1 stop5h 52m
Spirit Airlines
Tue 4/141:20 pm
CLT
-
TPA
1 stop9h 58m
Spirit Airlines
Deal found 3/15$136
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:27 pm
TPA
-
GSP
Nonstop1h 40m
Breeze Airways
Sun 4/192:12 pm
GSP
-
TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/16$137
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
-
MYR
Nonstop1h 38m
Breeze Airways
Mon 5/46:18 pm
MYR
-
TPA
Nonstop1h 42m
Breeze Airways
Deal found 3/15$137

Find flight deals from Tampa to South Carolina

Keep the following information in mind while searching for Tampa to South Carolina flight deals. Data was last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$112
(Flightnetwork)

One-way from

$48
(Booking.com)

Popular in

October

Cheapest in

January

Average price

$231

Good round-trip deal

$158 or less

Good one-way deal

$84 or less
Provider with most accurate pricing for Tampa-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Tampa-Myrtle Beach Intl flights.
Search Deals
From Tampa to South Carolina
Search Deals
One-way flight from Tampa to South Carolina
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Tampa to South Carolina.
Search Deals
Price to beat on a one-way flight from Tampa to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tampa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Tampa to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaGreenville

TPA - GSP

TPAGSP

Tampa

Thu 4/16

11:32 am-1:12 pm

Nonstop1h 40m

Greenville

Sun 4/19

2:12 pm-3:52 pm

Nonstop1h 40m

$118
Quickest round-trip

TampaCharleston

TPA - CHS

TPACHS

Tampa

Mon 4/13

8:23 pm-9:53 pm

Nonstop1h 30m

Charleston

Fri 4/17

8:28 pm-9:57 pm

Nonstop1h 29m

$153

TampaMyrtle Beach

TPA - MYR

TPAMYR

Tampa

Fri 5/1

10:42 am-12:20 pm

Nonstop1h 38m

Myrtle Beach Intl

Sun 5/3

6:59 pm-8:41 pm

Nonstop1h 42m

$153

TampaMyrtle Beach

TPA - MYR

TPAMYR

Tampa

Thu 4/16

10:05 am-11:43 am

Nonstop1h 38m

Myrtle Beach Intl

Mon 4/20

6:18 pm-8:00 pm

Nonstop1h 42m

$158

TampaCharleston

TPA - CHS

TPACHS

Tampa

Sat 4/18

10:05 am-11:35 am

Nonstop1h 30m

Charleston

Mon 4/20

8:28 pm-9:57 pm

Nonstop1h 29m

$163

TampaMyrtle Beach

TPA - MYR

TPAMYR

Tampa

Thu 5/14

10:38 am-12:19 pm

Nonstop1h 41m

Myrtle Beach Intl

Mon 5/18

6:14 pm-7:51 pm

Nonstop1h 37m

$178

TampaCharleston

TPA - CHS

TPACHS

Tampa

Sat 5/2

8:45 am-10:15 am

Nonstop1h 30m

Charleston

Sun 5/3

10:48 pm-12:17 am

Nonstop1h 29m

$183

TampaGreenville

TPA - GSP

TPAGSP

Tampa

Thu 4/9

11:32 am-1:12 pm

Nonstop1h 40m

Greenville

Sun 4/12

2:12 pm-3:52 pm

Nonstop1h 40m

$188

TampaMyrtle Beach

TPA - MYR

TPAMYR

Tampa

Fri 5/8

9:58 am-11:39 am

Nonstop1h 41m

Myrtle Beach Intl

Sun 5/10

6:12 pm-7:49 pm

Nonstop1h 37m

$188

TampaMyrtle Beach

TPA - MYR

TPAMYR

Tampa

Fri 5/1

3:53 pm-11:29 pm

1 stop7h 36m

Myrtle Beach Intl

Sun 5/3

6:59 pm-8:41 pm

Nonstop1h 42m

$200

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/16

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Tampa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Tampa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to South Carolina

What is the cheapest month to book a flight from Tampa to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Tampa to South Carolina (average of $46). Flying from Tampa to South Carolina in February is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TPA to SC?

Find hourly flight availability from Tampa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 17, 2026.

Unlike at noon, when flights are generally more expensive, you can save up to 28% on flights from Tampa to South Carolina by exploring options for tickets in the evening.

What is the cheapest day to fly from Tampa to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Tampa to South Carolina. Price data was last updated on March 14, 2026.

Travelers seeking maximum savings on their Tampa to South Carolina flight should consider departing on Friday afternoons when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 17, 2026.
See what other customers who have flown with Breeze Airways,Delta, andAllegiant Air from Tampa to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Boarding

8.3

Comfort

8.2

Crew

8.7

Food

6.6

Overall

8.1

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.1
Very good
271 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Boarding

8.3

Comfort

8.2

Crew

8.7

Food

6.6

Overall

8.1

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Delta
7.9
Good
8,288 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Boarding

8.3

Comfort

8.2

Crew

8.7

Food

6.6

Overall

8.1

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Allegiant Air
7.3
Good
712 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Boarding

8.3

Comfort

8.2

Crew

8.7

Food

6.6

Overall

8.1

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.1
Good
11,467 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Boarding

8.3

Comfort

8.2

Crew

8.7

Food

6.6

Overall

8.1

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Spirit Airlines
6.3
Okay
8,521 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Boarding

8.3

Comfort

8.2

Crew

8.7

Food

6.6

Overall

8.1

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Tampa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Tampa to South Carolina?

    Tampa (TPA), located 4.9 mi from the city center, is the airport you fly out of when you book flights from Tampa to South Carolina.

  • How popular is this Tampa to South Carolina flight route?

    This flight path from Tampa to South Carolina was viewed by 16 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Tampa to South Carolina?

    A quick flight from Tampa to South Carolina can take about 1h 40m. Breeze Airways provides one of the quickest options available for as low as $118. The distance between Tampa and South Carolina is about 478 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Tampa to South Carolina one-way?

    One-way options have recently been found by users for as low as $45 on Spirit Airlines. Other airlines that offer cheap prices include Breeze Airways from $49 and Delta from $79 one-way.

  • What are the most popular routes from Tampa to South Carolina?

    When deciding which route to take from Tampa to South Carolina consider Tampa - Charlotte Douglas, Tampa - Charleston or Tampa - Savannah/Hilton Head as they are the most popular.

  • What are the cheapest flights from Tampa to South Carolina?

    Looking at all options, your cheapest flight can be booked for $59. While the most popular route (Tampa - Charlotte Douglas) can be booked for $136 on average, our data indicates $191 when flying from Tampa to South Carolina.

  • Can I find deals for flights from Tampa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Tampa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tampa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tampa to South Carolina.

  • Can I find deals for business class flights from Tampa to South Carolina?

    Yes. Cheapflights offers flight deals from Tampa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Tampa to South Carolina (average of $46). Flying from Tampa to South Carolina in February is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Tampa to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Tampa to South Carolina

Discover the top 5 airlines that operate flights from Tampa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$48Average$99FlexibilityNo cancel feeOn-time88%
DeltaCheapest$79Average$304FlexibilityNo cancel feeOn-timeN/A
Breeze AirwaysCheapest$93Average$187FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$94Average$129FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$174Average$339FlexibilityNo cancel feeOn-time71%

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