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South Carolina

$44+ Cheap flights from Tampa (TPA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — CHS
Dec 18 — Dec 251
Thu 12/18
Thu 12/25
1 adult, Economy
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Find flight deals from Tampa to South Carolina

Cheapest flights from Tampa to South Carolina
Explore the most affordable flight options available from Tampa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 18, 2025.

This Super.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:12 pmTPA - CLT
Nonstop1h 48mFrontier
Sun 12/148:44 amCLT - TPA
Nonstop1h 54mFrontier
Deal found 11/17$109
This Priceline deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:28 pmTPA - CLT
1 stop10h 31mFrontier
Sun 12/78:44 amCLT - TPA
Nonstop1h 54mFrontier
Deal found 11/16$110
This CheapOair deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:28 pmTPA - CLT
1 stop10h 31mFrontier
Fri 12/128:55 pmCLT - TPA
Nonstop1h 54mFrontier
Deal found 11/16$111
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:07 pmTPA - CLT
1 stop3h 52mSpirit Airlines
Tue 12/92:58 pmCLT - TPA
1 stop3h 57mSpirit Airlines
Deal found 11/16$113
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:10 amTPA - MYR
Nonstop1h 34mBreeze Airways
Mon 11/242:14 pmMYR - TPA
Nonstop1h 42mBreeze Airways
Deal found 11/17$117
This Breeze Airways deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:10 amTPA - MYR
Nonstop1h 34mBreeze Airways
Mon 12/82:14 pmMYR - TPA
Nonstop1h 42mBreeze Airways
Deal found 11/16$118
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:07 pmTPA - CLT
1 stop3h 52mSpirit Airlines
Tue 12/92:58 pmCLT - TPA
1 stop3h 57mSpirit Airlines
Deal found 11/18$121
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:07 pmTPA - CLT
1 stop3h 52mMultiple Airlines
Fri 12/128:55 pmCLT - TPA
Nonstop1h 54mMultiple Airlines
Deal found 11/18$122
This Breeze Airways deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:10 amTPA - MYR
Nonstop1h 34mBreeze Airways
Mon 11/242:14 pmMYR - TPA
Nonstop1h 42mBreeze Airways
Deal found 11/17$123
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:07 pmTPA - CLT
1 stop3h 52mMultiple Airlines
Sun 12/78:44 amCLT - TPA
Nonstop1h 54mMultiple Airlines
Deal found 11/16$123
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/253:07 pmTPA - CLT
Nonstop1h 43mSpirit Airlines
Tue 12/92:58 pmCLT - TPA
1 stop3h 57mSpirit Airlines
Deal found 11/17$125
This CheapOair deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:28 pmTPA - CLT
1 stop10h 31mFrontier
Sun 12/148:44 amCLT - TPA
Nonstop1h 54mFrontier
Deal found 11/17$128

Cheap flight deals from Tampa to South Carolina

Keep the following information in mind while searching for Tampa to South Carolina flight deals. Data was last updated November 18, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$101
(Kiwi.com)

One-way from

$44
(Orbitz)

Popular in

May

Cheapest in

January

Average price

$171

Good round-trip deal

$163 or less

Good one-way deal

$48 or less
Provider with most accurate pricing for Tampa-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Tampa-Myrtle Beach Intl flights.
Search Deals
From Tampa to South Carolina
Search Deals
One-way flight from Tampa to South Carolina
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($69 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Tampa to South Carolina.
Search Deals
Price to beat on a one-way flight from Tampa to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tampa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from Tampa to South Carolina that are best for you.

Fly from

Tampa

Fly to

South Carolina

Route

Depart

Return

Price

TampaCharlotte

TPA - CLT

TPACLT

Tampa

Fri 12/12

6:12 pm-8:00 pm

Nonstop1h 48m

Charlotte Douglas

Sun 12/14

8:44 am-10:38 am

Nonstop1h 54m

$109

TampaMyrtle Beach

TPA - MYR

TPAMYR

Tampa

Mon 1/12

10:05 am-11:43 am

Nonstop1h 38m

Myrtle Beach Intl

Fri 1/16

6:09 pm-7:51 pm

Nonstop1h 42m

$117

TampaMyrtle Beach

TPA - MYR

TPAMYR

Tampa

Fri 12/5

7:10 am-8:44 am

Nonstop1h 34m

Myrtle Beach Intl

Mon 12/8

2:14 pm-3:56 pm

Nonstop1h 42m

$118

TampaMyrtle Beach

TPA - MYR

TPAMYR

Tampa

Mon 11/24

7:10 am-8:44 am

Nonstop1h 34m

Myrtle Beach Intl

Mon 11/24

2:14 pm-3:56 pm

Nonstop1h 42m

$123

TampaCharlotte

TPA - CLT

TPACLT

Tampa

Thu 12/4

9:28 pm-7:59 am

1 stop10h 31m

Charlotte Douglas

Fri 12/5

2:58 pm-6:55 pm

1 stop3h 57m

$129

TampaCharlotte

TPA - CLT

TPACLT

Tampa

Sun 12/21

9:39 pm-7:59 am

1 stop10h 20m

Charlotte Douglas

Mon 12/22

5:56 pm-7:50 pm

Nonstop1h 54m

$133

TampaCharlotte

TPA - CLT

TPACLT

Tampa

Fri 12/19

9:39 pm-7:59 am

1 stop10h 20m

Charlotte Douglas

Mon 12/22

5:56 pm-7:50 pm

Nonstop1h 54m

$133

TampaCharlotte

TPA - CLT

TPACLT

Tampa

Sat 12/6

8:07 pm-12:02 pm

2 stops15h 55m

Charlotte Douglas

Tue 12/9

2:58 pm-6:55 pm

1 stop3h 57m

$137

TampaCharleston

TPA - CHS

TPACHS

Tampa

Sat 12/6

1:01 pm-2:29 pm

Nonstop1h 28m

Charleston

Wed 12/10

8:10 pm-9:39 pm

Nonstop1h 29m

$138

TampaMyrtle Beach

TPA - MYR

TPAMYR

Tampa

Fri 12/5

7:10 am-8:44 am

Nonstop1h 34m

Myrtle Beach Intl

Mon 12/8

9:54 am-5:20 pm

1 stop7h 26m

$141

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Showing 1-10 of 60 results
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Best time to book a flight from Tampa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Tampa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to South Carolina

What is the cheapest month to book a flight from Tampa to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Tampa to South Carolina (average of $39). Flying from Tampa to South Carolina in January is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TPA to SC?

Find hourly flight availability from Tampa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 18, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 11% on flights from Tampa to South Carolina by exploring options for tickets at noon.

What is the cheapest day to fly from Tampa to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Tampa to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Tampa to South Carolina flight should consider departing on Friday mornings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 18, 2025.
See what other customers who have flown with Breeze Airways, Delta, and American Airlines from Tampa to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
234 reviews

Crew

8.8

Boarding

8.3

Food

6.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!
Breeze Airways
8.1
Very good
234 reviews
Breeze Airways
8.1
Very good
234 reviews

Crew

8.8

Boarding

8.3

Food

6.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!
Delta
7.9
Good
8,003 reviews
Breeze Airways
8.1
Very good
234 reviews

Crew

8.8

Boarding

8.3

Food

6.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!
American Airlines
7.2
Good
11,044 reviews
Breeze Airways
8.1
Very good
234 reviews

Crew

8.8

Boarding

8.3

Food

6.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!
Allegiant Air
7.2
Good
700 reviews
Breeze Airways
8.1
Very good
234 reviews

Crew

8.8

Boarding

8.3

Food

6.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!
Spirit Airlines
6.3
Okay
8,151 reviews
Breeze Airways
8.1
Very good
234 reviews

Crew

8.8

Boarding

8.3

Food

6.7

Comfort

8.2

Entertainment

6.6

Overall

8.1

Reviews

1 / 14
10.0
Excellent

Kim,Nov 2025

PWM - RSW

You guys did a great job getting us here. Thank you!!

Related info for your journey

Find useful and relevant information for your journey from Tampa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Tampa to South Carolina?

    Tampa (TPA), located 4.9 mi from the city center, is the airport you fly out of when you book flights from Tampa to South Carolina.

  • How popular is this Tampa to South Carolina flight route?

    This flight path from Tampa to South Carolina was viewed by 19 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Tampa to South Carolina?

    A quick flight from Tampa to South Carolina can take about 1h 38m. Frontier provides one of the quickest options available for as low as $117. The distance between Tampa and South Carolina is about 448 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Tampa to South Carolina one-way?

    One-way options have recently been found by users for as low as $44 on Breeze Airways. Other airlines that offer cheap prices include Frontier from $56 and Spirit Airlines from $58 one-way.

  • What are the most popular routes from Tampa to South Carolina?

    When deciding which route to take from Tampa to South Carolina consider Tampa - Charlotte Douglas, Tampa - Charleston or Tampa - Savannah/Hilton Head as they are the most popular.

  • What are the cheapest flights from Tampa to South Carolina?

    Looking at all options, your cheapest flight can be booked for $49. While the most popular route (Tampa - Charlotte Douglas) can be booked for $111 on average, our data indicates $256 when flying from Tampa to South Carolina.

  • Can I find deals for flights from Tampa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Tampa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tampa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tampa to South Carolina.

  • Can I find deals for business class flights from Tampa to South Carolina?

    Yes. Cheapflights offers flight deals from Tampa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Tampa to South Carolina (average of $39). Flying from Tampa to South Carolina in January is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Tampa to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Tampa to South Carolina

Discover the top 6 airlines that operate flights from Tampa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$78Average$99FlexibilityNo cancel feeOn-time88%
Breeze AirwaysCheapest$86Average$179FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$95Average$184FlexibilityNo cancel feeOn-time65%
DeltaCheapest$115Average$308FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$156Average$366FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$176Average$345FlexibilityNo cancel feeOn-time71%

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