$50+ Cheap flights from Tampa (TPA) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — CHS
May 26 — Jun 21
Round-trip
1 adult, Economy
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Find cheap flights from Tampa to South Carolina with Cheapflights
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Cheapest flights from Tampa to South CarolinaExplore the most affordable flight options available from Tampa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 26, 2026.
Explore the most affordable flight options available from Tampa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 26, 2026.
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/109:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 6/159:05 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$105
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1212:49 pm
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 6/159:05 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$111
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 6/16:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:58 pm
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Tue 9/811:07 am
GSP
- TPA
Nonstop1h 38m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/109:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Fri 6/129:05 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$122
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:05 am
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Mon 6/2910:26 am
GSP
- TPA
Nonstop1h 38m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1212:49 pm
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Fri 6/129:05 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$127
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/198:05 am
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Mon 6/2210:26 am
GSP
- TPA
Nonstop1h 38m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$128
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:05 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Fri 5/86:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$128
This Priceline deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:38 am
TPA
- MYR
Nonstop1h 41m
Multiple Airlines
Thu 5/143:31 pm
MYR
- TPA
1 stop5h 38m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/109:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Thu 6/189:07 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:52 pm
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Mon 9/78:13 pm
GSP
- TPA
Nonstop1h 38m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$133
Best flights from Tampa to South CarolinaDiscover carefully curated flight deals from Tampa to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 26, 2026.
Discover carefully curated flight deals from Tampa to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 26, 2026.
This Breeze Airways deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 5/186:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$143
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:55 pm
TPA
- CHS
1 stop4h 05m
Southwest
Wed 6/37:40 am
CHS
- TPA
1 stop7h 35m
Southwest
Deal found 4/26![Southwest logo]()
$179
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:54 pm
TPA
- CHS
1 stop4h 25m
Delta
Wed 8/129:30 am
CHS
- TPA
1 stop4h 11m
Delta
Deal found 4/25![Delta logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:56 pm
TPA
- MYR
1 stop6h 40m
Multiple Airlines
Sat 6/139:59 pm
MYR
- TPA
2 stops20h 52m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$224
This Breeze Airways deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:56 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Wed 7/158:56 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$153
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:57 pm
TPA
- CAE
1 stop5h 02m
United Airlines
Tue 5/192:20 pm
CAE
- TPA
1 stop7h 57m
United Airlines
Deal found 4/24![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
TPA
- HHH
2 stops8h 54m
American Airlines
Sat 7/115:38 pm
HHH
- TPA
1 stop3h 45m
American Airlines
Deal found 4/25![American Airlines logo]()
$390
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:57 pm
TPA
- CHS
1 stop4h 39m
Delta
Thu 6/255:10 am
CHS
- TPA
1 stop3h 43m
Delta
Deal found 4/25![Delta logo]()
$206
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:56 pm
TPA
- CHS
1 stop4h 03m
Delta
Fri 5/155:15 am
CHS
- TPA
1 stop3h 38m
Delta
Deal found 4/23![Delta logo]()
$207
This Breeze Airways deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:36 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Sun 10/256:25 pm
MYR
- TPA
Nonstop1h 39m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$208
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:55 pm
TPA
- CHS
1 stop5h 20m
Southwest
Tue 5/197:15 am
CHS
- TPA
2 stops8h 40m
Southwest
Deal found 4/23![Southwest logo]()
$245
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:50 am
TPA
- CHS
1 stop6h 13m
Delta
Tue 5/195:15 am
CHS
- TPA
1 stop4h 41m
Delta
Deal found 4/23![Delta logo]()
$207
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:20 am
TPA
- CHS
1 stop3h 53m
Delta
Wed 7/156:15 am
CHS
- TPA
1 stop3h 52m
Delta
Deal found 4/22![Delta logo]()
$217
This Breeze Airways deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:26 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Mon 5/119:28 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$248
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:10 pm
TPA
- CHS
1 stop6h 26m
Delta
Sat 6/271:10 pm
CHS
- TPA
1 stop6h 47m
Delta
Deal found 4/25![Delta logo]()
$217
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:30 am
TPA
- MYR
2 stops10h 15m
Southwest
Thu 5/141:45 pm
MYR
- TPA
1 stop6h 30m
Southwest
Deal found 4/21![Southwest logo]()
$305
This Breeze Airways deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/231:33 pm
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Sun 7/269:07 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/26![Breeze Airways logo]()
$258
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:55 pm
TPA
- CHS
1 stop5h 41m
Delta
Sat 6/205:03 pm
CHS
- TPA
1 stop5h 27m
Delta
Deal found 4/21![Delta logo]()
$217
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/254:35 pm
TPA
- SAV
1 stop5h 15m
Southwest
Wed 5/278:05 am
SAV
- TPA
2 stops9h 55m
Southwest
Deal found 4/24![Southwest logo]()
$316
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:00 am
TPA
- CLT
3 stops16h 40m
Multiple Airlines
Mon 6/86:06 pm
CLT
- TPA
3 stops18h 55m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$386
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:57 pm
TPA
- CAE
1 stop5h 02m
United Airlines
Wed 5/139:35 am
CAE
- TPA
1 stop7h 43m
United Airlines
Deal found 4/23![United Airlines logo]()
$389
This Breeze Airways deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Sun 5/106:12 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$268
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:20 am
TPA
- GSP
1 stop4h 58m
Delta
Sun 6/215:44 am
GSP
- TPA
1 stop3h 09m
Delta
Deal found 4/25![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:10 am
TPA
- SAV
2 stops10h 15m
Southwest
Sat 6/68:05 am
SAV
- TPA
2 stops10h 40m
Southwest
Deal found 4/21![Southwest logo]()
$321
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/148:30 am
TPA
- HHH
1 stop5h 43m
American Airlines
Wed 6/175:21 pm
HHH
- TPA
1 stop4h 36m
American Airlines
Deal found 4/21![American Airlines logo]()
$428
This Breeze Airways deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 6/86:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$268
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:20 am
TPA
- GSP
1 stop3h 58m
Delta
Fri 6/125:44 am
GSP
- TPA
1 stop3h 09m
Delta
Deal found 4/22![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:10 am
TPA
- SAV
2 stops8h 35m
Southwest
Mon 6/16:10 am
SAV
- TPA
2 stops8h 40m
Southwest
Deal found 4/21![Southwest logo]()
$322
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/199:30 am
TPA
- AGS
1 stop5h 30m
American Airlines
Sat 5/235:00 am
AGS
- TPA
1 stop4h 12m
American Airlines
Deal found 4/25![American Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:25 pm
TPA
- GSP
1 stop5h 54m
United Airlines
Fri 7/246:00 am
GSP
- TPA
2 stops9h 15m
United Airlines
Deal found 4/25![United Airlines logo]()
$471
Last-minute flights from Tampa to South CarolinaDiscover last-minute flight deals from Tampa to South Carolina. Data last updated April 26, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to South Carolina. Data last updated April 26, 2026 and is based on user searches.
This Breeze Airways deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Sun 5/36:59 pm
MYR
- TPA
Nonstop1h 42m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$138
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:05 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Fri 5/86:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$128
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Mon 5/119:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/22![Spirit Airlines logo]()
$148
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 5/116:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$145
This Booking.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:18 am
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Mon 5/119:28 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 4/22![Breeze Airways logo]()
$150
This Priceline deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:38 am
TPA
- MYR
Nonstop1h 41m
Multiple Airlines
Thu 5/143:31 pm
MYR
- TPA
1 stop5h 38m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$131
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Thu 5/146:12 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/22![Breeze Airways logo]()
$134
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Thu 5/146:12 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$135
This Expedia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:58 am
TPA
- MYR
Nonstop1h 41m
Multiple Airlines
Thu 5/146:00 am
MYR
- TPA
1 stop8h 58m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$148
This Breeze Airways deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 5/186:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$143
This Gotogate deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:58 pm
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Sun 5/313:40 pm
GSP
- TPA
Nonstop1h 38m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$136
This Booking.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Thu 5/286:12 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$141
One-way flights from Tampa to South CarolinaSearch for one-way flight options from Tampa to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 26, 2026.
Search for one-way flight options from Tampa to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 26, 2026.
This Booking.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 4/22![Breeze Airways logo]()
$50
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:05 am
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$54
This Booking.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:37 am
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Deal found 4/22![Breeze Airways logo]()
$54
This Booking.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$55
This Booking.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:56 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$58
This Booking.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:05 am
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$59
This Booking.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Deal found 4/22![Spirit Airlines logo]()
$64
This Cheapflightsfares deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Deal found 4/23![Spirit Airlines logo]()
$65
This Booking.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3011:18 am
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$67
This Booking.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:18 am
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$68
This Booking.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$68
Find flight deals from Tampa to South Carolina
Keep the following information in mind while searching for Tampa to South Carolina flight deals. Data was last updated April 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $105 (Mytrip) |
One-way from | $50 (Booking.com) |
Popular in | June |
Cheapest in | January |
Average price | $220 |
Good round-trip deal | $99 or less |
Good one-way deal | $78 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 26, 2026.
Use the filters below to find and compare flights from Tampa to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Thu 5/14
10:38 am-12:19 pm
Nonstop1h 41m
Myrtle Beach Intl
Mon 5/18
6:14 pm-7:51 pm
Nonstop1h 37m
$143
Quickest round-trip
TampaCharleston
TPA - CHS
TPACHS
Tampa
Wed 7/8
1:56 pm-3:28 pm
Nonstop1h 32m
Charleston
Wed 7/15
8:56 pm-10:23 pm
Nonstop1h 27m
$153
TampaCharleston
TPA - CHS
TPACHS
Tampa
Wed 5/27
3:55 pm-8:00 pm
1 stop4h 05m
Charleston
Wed 6/3
7:40 am-3:15 pm
1 stop7h 35m
$179
TampaCharleston
TPA - CHS
TPACHS
Tampa
Sun 8/9
6:54 pm-11:19 pm
1 stop4h 25m
Charleston
Wed 8/12
9:30 am-1:41 pm
1 stop4h 11m
$206
TampaCharleston
TPA - CHS
TPACHS
Tampa
Tue 6/23
7:57 pm-12:36 am
1 stop4h 39m
Charleston
Thu 6/25
5:10 am-8:53 am
1 stop3h 43m
$206
TampaCharleston
TPA - CHS
TPACHS
Tampa
Tue 5/12
7:56 pm-11:59 pm
1 stop4h 03m
Charleston
Fri 5/15
5:15 am-8:53 am
1 stop3h 38m
$207
TampaCharleston
TPA - CHS
TPACHS
Tampa
Sat 5/16
7:50 am-2:03 pm
1 stop6h 13m
Charleston
Tue 5/19
5:15 am-9:56 am
1 stop4h 41m
$207
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Thu 10/22
10:36 am-12:14 pm
Nonstop1h 38m
Myrtle Beach Intl
Sun 10/25
6:25 pm-8:04 pm
Nonstop1h 39m
$208
TampaCharleston
TPA - CHS
TPACHS
Tampa
Wed 7/8
6:20 am-10:13 am
1 stop3h 53m
Charleston
Wed 7/15
6:15 am-10:07 am
1 stop3h 52m
$217
TampaCharleston
TPA - CHS
TPACHS
Tampa
Sun 6/21
6:10 pm-12:36 am
1 stop6h 26m
Charleston
Sat 6/27
1:10 pm-7:57 pm
1 stop6h 47m
$217
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Tampa to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Tampa with our price prediction graph.
TPA-MYR
TPA-CHS
TPA-CAE
TPA-HHH
TPA-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Tampa to South Carolina
TPA-USSC
TPA-MYR
TPA-CHS
TPA-CAE
TPA-HHH
How far ahead should I book a flight from Tampa to South Carolina?
The price you pay for your flight from Tampa to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 69 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Tampa to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Tampa to South Carolina (average of $48). Flying from Tampa to South Carolina in March is currently the most expensive (average of $110). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TPA to SC?
Find hourly flight availability from Tampa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 26, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 19% on flights from Tampa to South Carolina by exploring options for tickets in the evening.
How much does it cost to fly round-trip from Tampa to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 26, 2026.
See what other customers who have flown with Breeze Airways,Delta, andAllegiant Air from Tampa to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.3
Comfort
8.2
Overall
8.1
Entertainment
6.6
Food
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Overall
8.1
Entertainment
6.6
Food
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Overall
8.1
Entertainment
6.6
Food
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Overall
8.1
Entertainment
6.6
Food
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Overall
8.1
Entertainment
6.6
Food
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Comfort
8.2
Overall
8.1
Entertainment
6.6
Food
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Tampa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Tampa to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Tampa to South Carolina by cabin class
Find flights from Tampa to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Tampa and South Carolina flights
Browse other Tampa and South Carolina flight options. Last updated on April 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Tampa to South Carolina flights
Consider these flights traveling from Tampa to South Carolina.
Top 5 airlines flying from Tampa to South Carolina
Discover the top 5 airlines that operate flights from Tampa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$48 | Average$96 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$79 | Average$299 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$94 | Average$188 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$94 | Average$129 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$167 | Average$354 | FlexibilityNo cancel fee | On-time71% |