$47+ Cheap flights from Tampa (TPA) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — CHS
May 11 — May 181
Round-trip
1 adult, Economy
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Find cheap flights from Tampa to South Carolina with Cheapflights
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Cheapest flights from Tampa to South CarolinaExplore the most affordable flight options available from Tampa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.
Explore the most affordable flight options available from Tampa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Tue 5/53:16 pm
CLT
- TPA
1 stop5h 35m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$107
This Cheapflightsfares deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Wed 5/133:16 pm
CLT
- TPA
1 stop5h 35m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$108
This Priceline deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Wed 5/133:16 pm
CLT
- TPA
1 stop5h 35m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$109
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Sat 5/169:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/6![Spirit Airlines logo]()
$114
This Mytrip deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:11 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Fri 5/86:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/9![Breeze Airways logo]()
$117
This Cheapflightsfares deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:26 am
TPA
- CLT
1 stop8h 36m
Spirit Airlines
Tue 5/127:30 am
CLT
- TPA
1 stop5h 31m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$117
This Cheapflightsfares deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Fri 5/89:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$118
This Expedia deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:01 am
TPA
- CLT
1 stop9h 43m
Multiple Airlines
Tue 5/53:16 pm
CLT
- TPA
1 stop5h 35m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$119
This Mytrip deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Mon 4/279:04 am
CLT
- TPA
1 stop10h 32m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$120
This Cheapflightsfares deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Mon 5/119:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/6![Spirit Airlines logo]()
$121
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Fri 4/2412:50 pm
CLT
- TPA
1 stop6h 46m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$122
This Booking.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Fri 5/86:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/7![Breeze Airways logo]()
$123
Best flights from Tampa to South CarolinaDiscover carefully curated flight deals from Tampa to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2026.
Discover carefully curated flight deals from Tampa to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2026.
This Breeze Airways deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 5/116:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/10![Breeze Airways logo]()
$133
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:55 pm
TPA
- CHS
1 stop4h 05m
Southwest
Sat 5/97:00 am
CHS
- TPA
1 stop5h 20m
Southwest
Deal found 4/6![Southwest logo]()
$199
This CheapOair deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:46 pm
TPA
- MYR
2 stops17h 02m
Spirit Airlines
Sat 5/306:30 am
MYR
- TPA
1 stop14h 21m
Spirit Airlines
Deal found 4/10![Spirit Airlines logo]()
$237
This Breeze Airways deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Sun 5/36:59 pm
MYR
- TPA
Nonstop1h 42m
Breeze Airways
Deal found 4/6![Breeze Airways logo]()
$148
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:30 pm
TPA
- CAE
1 stop5h 33m
United Airlines
Sat 5/162:37 pm
CAE
- TPA
1 stop6h 20m
United Airlines
Deal found 4/10![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:46 pm
TPA
- SAV
1 stop3h 43m
Delta
Sat 5/235:30 am
SAV
- TPA
1 stop4h 26m
Delta
Deal found 4/6![Delta logo]()
$327
This Breeze Airways deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:56 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Wed 7/158:56 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 4/10![Breeze Airways logo]()
$153
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:15 am
TPA
- AGS
1 stop5h 03m
American Airlines
Sat 6/278:54 am
AGS
- TPA
1 stop5h 40m
American Airlines
Deal found 4/10![American Airlines logo]()
$349
This Breeze Airways deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/198:05 am
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Tue 6/2311:07 am
GSP
- TPA
Nonstop1h 38m
Breeze Airways
Deal found 4/9![Breeze Airways logo]()
$153
This Breeze Airways deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:56 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Thu 6/118:20 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 4/6![Breeze Airways logo]()
$163
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:55 pm
TPA
- GSP
1 stop5h 45m
Southwest
Sat 5/96:25 am
GSP
- TPA
1 stop5h 05m
Southwest
Deal found 4/10![Southwest logo]()
$219
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:20 am
TPA
- GSP
1 stop5h 50m
Southwest
Fri 5/88:10 am
GSP
- TPA
1 stop7h 25m
Southwest
Deal found 4/6![Southwest logo]()
$229
This Breeze Airways deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/241:56 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Sat 6/278:56 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 4/8![Breeze Airways logo]()
$183
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:55 am
TPA
- GSP
1 stop6h 55m
Southwest
Thu 5/1412:35 pm
GSP
- TPA
1 stop4h 25m
Southwest
Deal found 4/9![Southwest logo]()
$229
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:55 pm
TPA
- GSP
1 stop5h 45m
Southwest
Wed 5/66:45 am
GSP
- TPA
1 stop5h 30m
Southwest
Deal found 4/6![Southwest logo]()
$229
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:57 pm
TPA
- CAE
1 stop5h 02m
United Airlines
Tue 5/52:37 pm
CAE
- TPA
1 stop6h 20m
United Airlines
Deal found 4/8![United Airlines logo]()
$329
This Breeze Airways deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:26 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Fri 5/159:28 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 4/7![Breeze Airways logo]()
$208
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:25 am
TPA
- MYR
1 stop5h 20m
Southwest
Tue 5/1911:15 am
MYR
- TPA
1 stop6h 50m
Southwest
Deal found 4/8![Southwest logo]()
$229
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:50 am
TPA
- SAV
1 stop4h 20m
Delta
Wed 5/275:30 am
SAV
- TPA
1 stop3h 23m
Delta
Deal found 4/6![Delta logo]()
$346
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
TPA
- AGS
1 stop6h 25m
American Airlines
Wed 5/1311:01 am
AGS
- TPA
1 stop5h 51m
American Airlines
Deal found 4/7![American Airlines logo]()
$359
This Breeze Airways deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2112:26 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Sat 6/278:56 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 4/8![Breeze Airways logo]()
$213
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:20 am
TPA
- MYR
2 stops9h 05m
Southwest
Wed 5/137:35 am
MYR
- TPA
2 stops10h 25m
Southwest
Deal found 4/6![Southwest logo]()
$239
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:20 am
TPA
- AGS
1 stop4h 49m
Delta
Wed 5/135:43 pm
AGS
- TPA
1 stop3h 18m
Delta
Deal found 4/9![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:15 am
TPA
- CAE
1 stop6h 50m
American Airlines
Sat 5/235:00 am
CAE
- TPA
1 stop4h 12m
American Airlines
Deal found 4/10![American Airlines logo]()
$367
This Breeze Airways deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Sun 5/106:12 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/6![Breeze Airways logo]()
$218
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:30 am
TPA
- GSP
2 stops9h 20m
Southwest
Wed 5/612:50 pm
GSP
- TPA
2 stops10h 05m
Southwest
Deal found 4/9![Southwest logo]()
$240
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:25 pm
TPA
- CAE
1 stop6h 56m
United Airlines
Wed 4/296:30 am
CAE
- TPA
1 stop6h 25m
United Airlines
Deal found 4/10![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:56 pm
TPA
- CAE
1 stop3h 51m
Delta
Sun 6/73:54 pm
CAE
- TPA
1 stop6h 36m
Delta
Deal found 4/9![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:00 pm
TPA
- AGS
2 stops6h 58m
American Airlines
Wed 5/63:03 pm
AGS
- TPA
1 stop6h 55m
American Airlines
Deal found 4/8![American Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:30 am
TPA
- GSP
2 stops9h 20m
Southwest
Sat 4/258:00 am
GSP
- TPA
2 stops9h 10m
Southwest
Deal found 4/8![Southwest logo]()
$245
Last-minute flights from Tampa to South CarolinaDiscover last-minute flight deals from Tampa to South Carolina. Data last updated April 11, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to South Carolina. Data last updated April 11, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Mon 4/279:04 am
CLT
- TPA
1 stop10h 32m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$120
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Fri 4/2412:50 pm
CLT
- TPA
1 stop6h 46m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$122
This Booking.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Fri 5/86:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/7![Breeze Airways logo]()
$123
This Cheapflightsfares deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Tue 5/53:16 pm
CLT
- TPA
1 stop5h 35m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$107
This Mytrip deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:11 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Fri 5/86:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/9![Breeze Airways logo]()
$117
This Priceline deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/33:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Tue 5/53:16 pm
CLT
- TPA
1 stop5h 35m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$123
This Expedia deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:01 am
TPA
- CLT
1 stop9h 43m
Multiple Airlines
Tue 5/53:16 pm
CLT
- TPA
1 stop5h 35m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$119
This Priceline deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Wed 5/133:16 pm
CLT
- TPA
1 stop5h 35m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$109
This Cheapflightsfares deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Wed 5/133:16 pm
CLT
- TPA
1 stop5h 35m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$108
This Cheapflightsfares deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:56 pm
TPA
- CLT
1 stop9h 44m
Spirit Airlines
Mon 5/119:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$118
This Cheapflightsfares deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:26 am
TPA
- CLT
1 stop8h 36m
Spirit Airlines
Tue 5/127:30 am
CLT
- TPA
1 stop5h 31m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$117
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Sat 5/169:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/6![Spirit Airlines logo]()
$114
One-way flights from Tampa to South CarolinaSearch for one-way flight options from Tampa to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 11, 2026.
Search for one-way flight options from Tampa to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 11, 2026.
This Booking.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:05 am
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 4/7![Breeze Airways logo]()
$47
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Deal found 4/6![Spirit Airlines logo]()
$47
This Booking.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:18 am
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/8![Breeze Airways logo]()
$52
This Booking.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Deal found 4/6![Breeze Airways logo]()
$54
This Cheapflightsfares deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$54
This Booking.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:05 am
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/7![Breeze Airways logo]()
$55
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$55
This Super.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2310:10 am
TPA
- CLT
1 stop4h 26m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$57
This Booking.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:05 am
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Deal found 4/9![Breeze Airways logo]()
$59
This Booking.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:56 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/6![Breeze Airways logo]()
$62
This Booking.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:37 am
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Deal found 4/9![Breeze Airways logo]()
$64
This Breeze Airways deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Deal found 4/6![Breeze Airways logo]()
$64
Find flight deals from Tampa to South Carolina
Keep the following information in mind while searching for Tampa to South Carolina flight deals. Data was last updated April 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $107 (Cheapflightsfares) |
One-way from | $47 (Booking.com) |
Popular in | June |
Cheapest in | January |
Average price | $237 |
Good round-trip deal | $104 or less |
Good one-way deal | $76 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
Use the filters below to find and compare flights from Tampa to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Fri 5/8
9:58 am-11:39 am
Nonstop1h 41m
Myrtle Beach Intl
Mon 5/11
6:14 pm-7:51 pm
Nonstop1h 37m
$133
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Fri 5/1
10:42 am-12:20 pm
Nonstop1h 38m
Myrtle Beach Intl
Sun 5/3
6:59 pm-8:41 pm
Nonstop1h 42m
$148
Quickest round-trip
TampaCharleston
TPA - CHS
TPACHS
Tampa
Wed 7/8
1:56 pm-3:28 pm
Nonstop1h 32m
Charleston
Wed 7/15
8:56 pm-10:23 pm
Nonstop1h 27m
$153
TampaGreenville
TPA - GSP
TPAGSP
Tampa
Fri 6/19
8:05 am-9:46 am
Nonstop1h 41m
Greenville
Tue 6/23
11:07 am-12:45 pm
Nonstop1h 38m
$153
TampaCharleston
TPA - CHS
TPACHS
Tampa
Mon 6/8
12:56 pm-2:28 pm
Nonstop1h 32m
Charleston
Thu 6/11
8:20 pm-9:47 pm
Nonstop1h 27m
$163
TampaCharleston
TPA - CHS
TPACHS
Tampa
Wed 6/24
1:56 pm-3:28 pm
Nonstop1h 32m
Charleston
Sat 6/27
8:56 pm-10:23 pm
Nonstop1h 27m
$183
TampaCharleston
TPA - CHS
TPACHS
Tampa
Wed 5/6
3:55 pm-8:00 pm
1 stop4h 05m
Charleston
Sat 5/9
7:00 am-12:20 pm
1 stop5h 20m
$199
TampaCharleston
TPA - CHS
TPACHS
Tampa
Thu 5/14
12:26 pm-1:58 pm
Nonstop1h 32m
Charleston
Fri 5/15
9:28 pm-10:55 pm
Nonstop1h 27m
$208
TampaCharleston
TPA - CHS
TPACHS
Tampa
Sun 6/21
12:26 pm-1:58 pm
Nonstop1h 32m
Charleston
Sat 6/27
8:56 pm-10:23 pm
Nonstop1h 27m
$213
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Fri 5/8
9:58 am-11:39 am
Nonstop1h 41m
Myrtle Beach Intl
Sun 5/10
6:12 pm-7:49 pm
Nonstop1h 37m
$218
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Tampa to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Tampa with our price prediction graph.
TPA-CLT
TPA-MYR
TPA-CAE
TPA-GSP
TPA-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Tampa to South Carolina
TPA-USSC
TPA-CLT
TPA-MYR
TPA-CAE
TPA-GSP
What is the cheapest month to book a flight from Tampa to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Tampa to South Carolina (average of $46). Flying from Tampa to South Carolina in March is currently the most expensive (average of $79). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TPA to SC?
Find hourly flight availability from Tampa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 11, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 23% on flights from Tampa to South Carolina by exploring options for tickets in the evening.
How much does it cost to fly round-trip from Tampa to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 11, 2026.
See what other customers who have flown with Breeze Airways,Delta, andAllegiant Air from Tampa to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.3
Entertainment
6.6
Overall
8.1
Crew
8.7
Comfort
8.2
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Entertainment
6.6
Overall
8.1
Crew
8.7
Comfort
8.2
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Entertainment
6.6
Overall
8.1
Crew
8.7
Comfort
8.2
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Entertainment
6.6
Overall
8.1
Crew
8.7
Comfort
8.2
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Entertainment
6.6
Overall
8.1
Crew
8.7
Comfort
8.2
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Entertainment
6.6
Overall
8.1
Crew
8.7
Comfort
8.2
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Tampa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Tampa to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Tampa to South Carolina by cabin class
Find flights from Tampa to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Tampa and South Carolina flights
Browse other Tampa and South Carolina flight options. Last updated on April 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Tampa to South Carolina flights
Consider these flights traveling from Tampa to South Carolina.
Top 5 airlines flying from Tampa to South Carolina
Discover the top 5 airlines that operate flights from Tampa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$48 | Average$103 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$79 | Average$304 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$94 | Average$188 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$94 | Average$129 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$174 | Average$345 | FlexibilityNo cancel fee | On-time71% |