$47+ Cheap flights from Tampa (TPA) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — CHS
May 18 — May 251
Round-trip
1 adult, Economy
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Find cheap flights from Tampa to South Carolina with Cheapflights
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Cheapest flights from Tampa to South CarolinaExplore the most affordable flight options available from Tampa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
Explore the most affordable flight options available from Tampa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Fri 5/159:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$108
This Priceline deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Wed 5/133:16 pm
CLT
- TPA
1 stop5h 35m
Spirit Airlines
Deal found 4/13![Spirit Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Fri 8/288:41 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/17![Breeze Airways logo]()
$117
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Sat 5/309:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$118
This Super.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:00 pm
TPA
- CLT
1 stop8h 02m
Spirit Airlines
Sat 5/912:29 pm
CLT
- TPA
1 stop8h 22m
Spirit Airlines
Deal found 4/16![Spirit Airlines logo]()
$119
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Mon 5/46:18 pm
MYR
- TPA
Nonstop1h 42m
Breeze Airways
Deal found 4/16![Breeze Airways logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:00 pm
TPA
- CLT
1 stop8h 02m
Spirit Airlines
Mon 5/119:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$123
This Mytrip deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:11 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Fri 5/86:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/14![Breeze Airways logo]()
$124
This Orbitz deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:27 pm
TPA
- CLT
1 stop7h 10m
Multiple Airlines
Sat 5/912:29 pm
CLT
- TPA
1 stop8h 22m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$126
This Mytrip deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 5/116:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/13![Breeze Airways logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:26 am
TPA
- CLT
1 stop8h 36m
Spirit Airlines
Mon 5/119:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/16![Spirit Airlines logo]()
$127
This Breeze Airways deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Fri 6/199:05 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/14![Breeze Airways logo]()
$128
Best flights from Tampa to South CarolinaDiscover carefully curated flight deals from Tampa to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
Discover carefully curated flight deals from Tampa to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
This Breeze Airways deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Sun 5/36:59 pm
MYR
- TPA
Nonstop1h 42m
Breeze Airways
Deal found 4/14![Breeze Airways logo]()
$143
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:30 am
TPA
- CHS
1 stop7h 00m
Southwest
Tue 8/116:45 am
CHS
- TPA
2 stops8h 05m
Southwest
Deal found 4/17![Southwest logo]()
$203
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:26 am
TPA
- CHS
1 stop4h 12m
Delta
Sat 5/305:20 am
CHS
- TPA
1 stop3h 33m
Delta
Deal found 4/16![Delta logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:26 pm
TPA
- CHS
Nonstop1h 32m
Multiple Airlines
Sun 8/237:25 am
CHS
- TPA
2 stops14h 04m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$225
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:46 pm
TPA
- CLT
1 stop13h 48m
Spirit Airlines
Mon 6/812:48 pm
CLT
- TPA
3 stops24h 13m
Spirit Airlines
Deal found 4/17![Spirit Airlines logo]()
$245
This Breeze Airways deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 6/229:05 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/13![Breeze Airways logo]()
$148
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:15 am
TPA
- CLT
Nonstop1h 56m
American Airlines
Sun 5/178:15 pm
CLT
- TPA
Nonstop1h 43m
American Airlines
Deal found 4/17![American Airlines logo]()
$355
This Breeze Airways deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:56 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Wed 7/158:56 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 4/15![Breeze Airways logo]()
$163
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:57 pm
TPA
- CAE
1 stop5h 02m
United Airlines
Mon 5/1110:34 am
CAE
- TPA
1 stop4h 54m
United Airlines
Deal found 4/13![United Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:20 am
TPA
- CHS
1 stop4h 53m
Delta
Thu 7/95:10 am
CHS
- TPA
1 stop3h 44m
Delta
Deal found 4/16![Delta logo]()
$217
This Breeze Airways deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Sun 5/316:12 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/15![Breeze Airways logo]()
$193
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:58 pm
TPA
- CHS
1 stop5h 28m
Delta
Wed 7/155:10 am
CHS
- TPA
1 stop6h 19m
Delta
Deal found 4/17![Delta logo]()
$217
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:46 pm
TPA
- CHS
1 stop5h 13m
Delta
Mon 5/187:59 pm
CHS
- TPA
1 stop4h 30m
Delta
Deal found 4/16![Delta logo]()
$217
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:20 am
TPA
- CHS
1 stop4h 58m
Delta
Sat 6/271:05 pm
CHS
- TPA
1 stop4h 46m
Delta
Deal found 4/16![Delta logo]()
$217
This Breeze Airways deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2112:26 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Sat 6/278:56 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 4/14![Breeze Airways logo]()
$218
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:35 pm
TPA
- GSP
1 stop6h 00m
Southwest
Wed 6/38:20 am
GSP
- TPA
1 stop6h 55m
Southwest
Deal found 4/13![Southwest logo]()
$305
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:30 am
TPA
- CHS
1 stop3h 55m
Delta
Sun 8/235:30 am
CHS
- TPA
1 stop3h 22m
Delta
Deal found 4/17![Delta logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:10 am
TPA
- SAV
1 stop12h 38m
Multiple Airlines
Sun 5/31:36 pm
SAV
- TPA
2 stops10h 50m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:59 am
TPA
- MYR
1 stop5h 28m
Delta
Mon 8/37:54 pm
MYR
- TPA
1 stop4h 36m
Delta
Deal found 4/17![Delta logo]()
$219
This Breeze Airways deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:38 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Sun 5/176:12 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/15![Breeze Airways logo]()
$243
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:25 am
TPA
- HHH
2 stops10h 13m
American Airlines
Wed 8/123:27 pm
HHH
- TPA
2 stops7h 46m
American Airlines
Deal found 4/15![American Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:10 am
TPA
- SAV
2 stops9h 50m
Southwest
Fri 5/158:05 am
SAV
- TPA
1 stop7h 30m
Southwest
Deal found 4/13![Southwest logo]()
$336
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:15 am
TPA
- HHH
1 stop6h 11m
American Airlines
Mon 5/186:39 pm
HHH
- TPA
1 stop5h 32m
American Airlines
Deal found 4/13![American Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:58 pm
TPA
- GSP
1 stop3h 56m
Delta
Tue 8/45:16 pm
GSP
- TPA
1 stop5h 14m
Delta
Deal found 4/17![Delta logo]()
$229
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:00 am
TPA
- GSP
1 stop5h 19m
United Airlines
Mon 8/242:55 pm
GSP
- TPA
1 stop5h 28m
United Airlines
Deal found 4/13![United Airlines logo]()
$417
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:15 am
TPA
- SAV
2 stops10h 55m
Southwest
Sat 6/68:30 pm
SAV
- TPA
2 stops12h 30m
Southwest
Deal found 4/17![Southwest logo]()
$355
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:57 pm
TPA
- GSP
1 stop4h 02m
Delta
Tue 6/235:16 pm
GSP
- TPA
1 stop5h 14m
Delta
Deal found 4/17![Delta logo]()
$229
This Breeze Airways deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1912:49 pm
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Sun 6/216:12 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/14![Breeze Airways logo]()
$288
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:25 am
TPA
- SAV
2 stops7h 30m
Southwest
Mon 5/1112:50 pm
SAV
- TPA
2 stops6h 30m
Southwest
Deal found 4/16![Southwest logo]()
$355
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:41 am
TPA
- AGS
1 stop4h 09m
American Airlines
Mon 5/115:00 am
AGS
- TPA
1 stop4h 55m
American Airlines
Deal found 4/17![American Airlines logo]()
$391
Last-minute flights from Tampa to South CarolinaDiscover last-minute flight deals from Tampa to South Carolina. Data last updated April 18, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to South Carolina. Data last updated April 18, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Mon 5/46:18 pm
MYR
- TPA
Nonstop1h 42m
Breeze Airways
Deal found 4/16![Breeze Airways logo]()
$122
This Mytrip deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:11 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Fri 5/86:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/14![Breeze Airways logo]()
$124
This Mytrip deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:11 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Mon 5/46:18 pm
MYR
- TPA
Nonstop1h 42m
Breeze Airways
Deal found 4/15![Breeze Airways logo]()
$129
This Orbitz deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:27 pm
TPA
- CLT
1 stop7h 10m
Multiple Airlines
Sat 5/912:29 pm
CLT
- TPA
1 stop8h 22m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$126
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Sat 5/309:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$118
This Super.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:00 pm
TPA
- CLT
1 stop8h 02m
Spirit Airlines
Sat 5/912:29 pm
CLT
- TPA
1 stop8h 22m
Spirit Airlines
Deal found 4/16![Spirit Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:00 pm
TPA
- CLT
1 stop8h 02m
Spirit Airlines
Mon 5/119:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$123
This Mytrip deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 5/116:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 4/13![Breeze Airways logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:26 am
TPA
- CLT
1 stop8h 36m
Spirit Airlines
Mon 5/119:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/16![Spirit Airlines logo]()
$127
This Cheapflightsfares deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:26 am
TPA
- CLT
1 stop8h 36m
Spirit Airlines
Fri 5/299:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/16![Spirit Airlines logo]()
$128
This Priceline deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Wed 5/133:16 pm
CLT
- TPA
1 stop5h 35m
Spirit Airlines
Deal found 4/13![Spirit Airlines logo]()
$109
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Fri 5/159:07 pm
CLT
- TPA
1 stop10h 23m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$108
One-way flights from Tampa to South CarolinaSearch for one-way flight options from Tampa to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
Search for one-way flight options from Tampa to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
This Booking.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:05 am
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 4/15![Breeze Airways logo]()
$47
This Booking.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:05 am
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/13![Breeze Airways logo]()
$52
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:05 am
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/16![Breeze Airways logo]()
$53
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:05 am
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/17![Breeze Airways logo]()
$54
This Booking.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Deal found 4/14![Breeze Airways logo]()
$54
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$54
This Booking.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:05 am
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 4/17![Breeze Airways logo]()
$55
This Super.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:25 am
TPA
- CLT
1 stop5h 46m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$55
This Booking.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:18 am
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/14![Breeze Airways logo]()
$57
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:56 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 4/17![Breeze Airways logo]()
$58
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Deal found 4/17![Breeze Airways logo]()
$58
This Breeze Airways deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:54 am
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 4/16![Breeze Airways logo]()
$59
Find flight deals from Tampa to South Carolina
Keep the following information in mind while searching for Tampa to South Carolina flight deals. Data was last updated April 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $108 (Cheapflightsfares) |
One-way from | $47 (Booking.com) |
Popular in | June |
Cheapest in | January |
Average price | $220 |
Good round-trip deal | $104 or less |
Good one-way deal | $76 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from Tampa to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Fri 5/1
10:42 am-12:20 pm
Nonstop1h 38m
Myrtle Beach Intl
Sun 5/3
6:59 pm-8:41 pm
Nonstop1h 42m
$143
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Thu 6/11
10:38 am-12:19 pm
Nonstop1h 41m
Myrtle Beach Intl
Mon 6/22
9:05 pm-10:42 pm
Nonstop1h 37m
$148
Quickest round-trip
TampaCharleston
TPA - CHS
TPACHS
Tampa
Wed 7/8
1:56 pm-3:28 pm
Nonstop1h 32m
Charleston
Wed 7/15
8:56 pm-10:23 pm
Nonstop1h 27m
$163
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Thu 5/28
10:38 am-12:19 pm
Nonstop1h 41m
Myrtle Beach Intl
Sun 5/31
6:12 pm-7:49 pm
Nonstop1h 37m
$193
TampaCharleston
TPA - CHS
TPACHS
Tampa
Tue 7/21
6:30 am-1:30 pm
1 stop7h 00m
Charleston
Tue 8/11
6:45 am-2:50 pm
2 stops8h 05m
$203
TampaCharleston
TPA - CHS
TPACHS
Tampa
Thu 5/28
5:26 am-9:38 am
1 stop4h 12m
Charleston
Sat 5/30
5:20 am-8:53 am
1 stop3h 33m
$217
TampaCharleston
TPA - CHS
TPACHS
Tampa
Tue 7/7
5:20 am-10:13 am
1 stop4h 53m
Charleston
Thu 7/9
5:10 am-8:54 am
1 stop3h 44m
$217
TampaCharleston
TPA - CHS
TPACHS
Tampa
Wed 7/8
6:58 pm-12:26 am
1 stop5h 28m
Charleston
Wed 7/15
5:10 am-11:29 am
1 stop6h 19m
$217
TampaCharleston
TPA - CHS
TPACHS
Tampa
Fri 5/15
6:46 pm-11:59 pm
1 stop5h 13m
Charleston
Mon 5/18
7:59 pm-12:29 am
1 stop4h 30m
$217
TampaCharleston
TPA - CHS
TPACHS
Tampa
Sun 6/21
5:20 am-10:18 am
1 stop4h 58m
Charleston
Sat 6/27
1:05 pm-5:51 pm
1 stop4h 46m
$217
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Tampa to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Tampa with our price prediction graph.
TPA-CLT
TPA-MYR
TPA-CHS
TPA-CAE
TPA-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Tampa to South Carolina
TPA-USSC
TPA-CLT
TPA-MYR
TPA-CHS
TPA-CAE
What is the cheapest month to book a flight from Tampa to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Tampa to South Carolina (average of $48). Flying from Tampa to South Carolina in March is currently the most expensive (average of $110). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TPA to SC?
Find hourly flight availability from Tampa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 18, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 23% on flights from Tampa to South Carolina by exploring options for tickets in the evening.
How much does it cost to fly round-trip from Tampa to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 18, 2026.
See what other customers who have flown with Breeze Airways,Delta, andAllegiant Air from Tampa to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.6
Crew
8.7
Overall
8.1
Boarding
8.3
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.6
Crew
8.7
Overall
8.1
Boarding
8.3
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.6
Crew
8.7
Overall
8.1
Boarding
8.3
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.6
Crew
8.7
Overall
8.1
Boarding
8.3
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.6
Crew
8.7
Overall
8.1
Boarding
8.3
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.6
Crew
8.7
Overall
8.1
Boarding
8.3
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Tampa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Tampa to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Tampa to South Carolina by cabin class
Find flights from Tampa to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Tampa and South Carolina flights
Browse other Tampa and South Carolina flight options. Last updated on April 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Tampa to South Carolina flights
Consider these flights traveling from Tampa to South Carolina.
Top 5 airlines flying from Tampa to South Carolina
Discover the top 5 airlines that operate flights from Tampa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$48 | Average$103 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$79 | Average$304 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$94 | Average$188 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$94 | Average$129 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$174 | Average$345 | FlexibilityNo cancel fee | On-time71% |