$53+ Cheap flights from Tampa (TPA) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — CHS
Apr 24 — May 11
Round-trip
1 adult, Economy
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Find cheap flights from Tampa to South Carolina with Cheapflights
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Cheapest flights from Tampa to South CarolinaExplore the most affordable flight options available from Tampa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.
Explore the most affordable flight options available from Tampa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.
This Priceline deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Wed 4/2212:50 pm
CLT
- TPA
1 stop6h 46m
Spirit Airlines
Deal found 3/25![Spirit Airlines logo]()
$115
This Booking.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:05 am
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Mon 6/2910:26 am
GSP
- TPA
Nonstop1h 38m
Breeze Airways
Deal found 3/24![Breeze Airways logo]()
$124
This Gotogate deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:32 am
TPA
- GSP
Nonstop1h 40m
Breeze Airways
Mon 5/44:07 pm
GSP
- TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/23![Breeze Airways logo]()
$127
This Booking.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:05 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Mon 5/116:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 3/20![Breeze Airways logo]()
$128
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Wed 4/2912:50 pm
CLT
- TPA
1 stop6h 46m
Spirit Airlines
Deal found 3/24![Spirit Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:05 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Fri 5/86:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 3/23![Breeze Airways logo]()
$132
This Breeze Airways deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:32 am
TPA
- GSP
Nonstop1h 40m
Breeze Airways
Sun 4/192:12 pm
GSP
- TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/25![Breeze Airways logo]()
$133
This Breeze Airways deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Fri 6/129:05 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 3/21![Breeze Airways logo]()
$133
This Booking.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 5/116:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 3/23![Breeze Airways logo]()
$135
This Expedia deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:09 am
TPA
- CLT
1 stop5h 37m
Multiple Airlines
Tue 4/2112:50 pm
CLT
- TPA
1 stop6h 46m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:27 pm
TPA
- GSP
Nonstop1h 40m
Breeze Airways
Thu 4/232:12 pm
GSP
- TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/20![Breeze Airways logo]()
$137
This Booking.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:27 pm
TPA
- GSP
Nonstop1h 40m
Breeze Airways
Fri 5/14:07 pm
GSP
- TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/24![Breeze Airways logo]()
$139
Best flights from Tampa to South CarolinaDiscover carefully curated flight deals from Tampa to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2026.
Discover carefully curated flight deals from Tampa to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2026.
This Breeze Airways deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Mon 5/116:14 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 3/25![Breeze Airways logo]()
$138
This Spirit Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:59 pm
TPA
- MYR
1 stop24h 59m
Spirit Airlines
Sat 5/1611:52 am
MYR
- TPA
1 stop10h 19m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:50 am
TPA
- CHS
2 stops8h 50m
Southwest
Fri 5/84:45 pm
CHS
- TPA
1 stop6h 10m
Southwest
Deal found 3/25![Southwest logo]()
$241
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:26 am
TPA
- GSP
1 stop3h 38m
Delta
Mon 5/117:42 pm
GSP
- TPA
1 stop4h 47m
Delta
Deal found 3/21![Delta logo]()
$279
This Breeze Airways deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:05 am
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Tue 4/214:03 pm
CHS
- TPA
Nonstop1h 29m
Breeze Airways
Deal found 3/21![Breeze Airways logo]()
$148
This Breeze Airways deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:05 am
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Mon 4/208:28 pm
CHS
- TPA
Nonstop1h 29m
Breeze Airways
Deal found 3/25![Breeze Airways logo]()
$148
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/129:00 am
TPA
- CAE
1 stop5h 16m
United Airlines
Mon 6/152:51 pm
CAE
- TPA
1 stop5h 48m
United Airlines
Deal found 3/24![United Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:41 am
TPA
- HHH
1 stop4h 53m
American Airlines
Sat 5/96:50 pm
HHH
- TPA
1 stop5h 32m
American Airlines
Deal found 3/25![American Airlines logo]()
$345
This Breeze Airways deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:32 am
TPA
- GSP
Nonstop1h 40m
Breeze Airways
Sun 4/192:12 pm
GSP
- TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/22![Breeze Airways logo]()
$148
This Breeze Airways deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Mon 5/46:18 pm
MYR
- TPA
Nonstop1h 42m
Breeze Airways
Deal found 3/21![Breeze Airways logo]()
$153
This Breeze Airways deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Sun 5/36:59 pm
MYR
- TPA
Nonstop1h 42m
Breeze Airways
Deal found 3/25![Breeze Airways logo]()
$163
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2110:10 am
TPA
- SAV
2 stops9h 50m
Southwest
Tue 4/288:05 am
SAV
- TPA
2 stops10h 00m
Southwest
Deal found 3/24![Southwest logo]()
$243
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:50 am
TPA
- CHS
1 stop5h 15m
Southwest
Tue 4/287:15 am
CHS
- TPA
2 stops8h 00m
Southwest
Deal found 3/21![Southwest logo]()
$244
This Breeze Airways deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:56 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Wed 7/158:56 pm
CHS
- TPA
Nonstop1h 27m
Breeze Airways
Deal found 3/23![Breeze Airways logo]()
$168
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:46 pm
TPA
- GSP
1 stop5h 57m
Delta
Sun 5/175:40 am
GSP
- TPA
1 stop3h 13m
Delta
Deal found 3/24![Delta logo]()
$287
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:35 am
TPA
- MYR
2 stops8h 55m
Southwest
Thu 4/163:45 pm
MYR
- TPA
1 stop5h 25m
Southwest
Deal found 3/25![Southwest logo]()
$248
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:35 am
TPA
- HHH
1 stop6h 45m
Delta
Sat 5/912:18 pm
HHH
- TPA
1 stop5h 25m
Delta
Deal found 3/24![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:35 am
TPA
- GSP
2 stops8h 25m
Southwest
Thu 5/1412:35 pm
GSP
- TPA
2 stops6h 45m
Southwest
Deal found 3/23![Southwest logo]()
$261
This Booking.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:23 pm
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Mon 4/138:28 pm
CHS
- TPA
Nonstop1h 29m
Breeze Airways
Deal found 3/25![Breeze Airways logo]()
$198
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:15 am
TPA
- AGS
1 stop5h 12m
American Airlines
Mon 5/118:23 pm
AGS
- TPA
1 stop3h 48m
American Airlines
Deal found 3/23![American Airlines logo]()
$371
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/199:00 am
TPA
- CAE
1 stop5h 10m
United Airlines
Sat 8/226:30 am
CAE
- TPA
2 stops8h 40m
United Airlines
Deal found 3/20![United Airlines logo]()
$384
This Breeze Airways deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:05 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Mon 4/206:18 pm
MYR
- TPA
Nonstop1h 42m
Breeze Airways
Deal found 3/21![Breeze Airways logo]()
$198
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:20 am
TPA
- SAV
2 stops10h 10m
Southwest
Tue 6/96:45 am
SAV
- TPA
2 stops7h 55m
Southwest
Deal found 3/25![Southwest logo]()
$271
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:00 am
TPA
- HHH
1 stop4h 32m
American Airlines
Sat 4/256:50 pm
HHH
- TPA
1 stop5h 32m
American Airlines
Deal found 3/25![American Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:20 am
TPA
- AGS
1 stop4h 15m
Delta
Sat 6/207:22 pm
AGS
- TPA
1 stop5h 09m
Delta
Deal found 3/22![Delta logo]()
$367
This Breeze Airways deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:58 am
TPA
- MYR
Nonstop1h 41m
Breeze Airways
Sun 5/106:12 pm
MYR
- TPA
Nonstop1h 37m
Breeze Airways
Deal found 3/23![Breeze Airways logo]()
$213
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:00 am
TPA
- SAV
1 stop6h 40m
Southwest
Wed 5/131:05 pm
SAV
- TPA
1 stop5h 30m
Southwest
Deal found 3/20![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:00 am
TPA
- CAE
1 stop5h 59m
Delta
Sun 4/265:47 pm
CAE
- TPA
1 stop5h 29m
Delta
Deal found 3/21![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:15 am
TPA
- CAE
1 stop7h 34m
United Airlines
Mon 4/202:38 pm
CAE
- TPA
1 stop6h 13m
United Airlines
Deal found 3/22![United Airlines logo]()
$453
This Breeze Airways deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:05 am
TPA
- MYR
Nonstop1h 38m
Breeze Airways
Sun 4/195:53 pm
MYR
- TPA
Nonstop1h 42m
Breeze Airways
Deal found 3/21![Breeze Airways logo]()
$228
Last-minute flights from Tampa to South CarolinaDiscover last-minute flight deals from Tampa to South Carolina. Data last updated March 25, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to South Carolina. Data last updated March 25, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:46 pm
TPA
- CHS
1 stop3h 27m
Spirit Airlines
Wed 4/18:07 am
CHS
- TPA
1 stop9h 34m
Spirit Airlines
Deal found 3/24![Spirit Airlines logo]()
$142
This Breeze Airways deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:05 am
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Sat 4/185:16 pm
CHS
- TPA
Nonstop1h 29m
Breeze Airways
Deal found 3/24![Breeze Airways logo]()
$143
This Priceline deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:46 pm
TPA
- CHS
1 stop3h 27m
Multiple Airlines
Sat 4/185:16 pm
CHS
- TPA
Nonstop1h 29m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$144
This Priceline deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Wed 4/2212:50 pm
CLT
- TPA
1 stop6h 46m
Spirit Airlines
Deal found 3/25![Spirit Airlines logo]()
$115
This CheapOair deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:53 pm
TPA
- CLT
1 stop4h 56m
Multiple Airlines
Sun 4/196:10 pm
CLT
- TPA
1 stop27h 40m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$145
This Breeze Airways deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:32 am
TPA
- GSP
Nonstop1h 40m
Breeze Airways
Sun 4/192:12 pm
GSP
- TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/25![Breeze Airways logo]()
$133
This Super.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:00 pm
TPA
- CLT
1 stop7h 28m
Frontier
Mon 4/2010:13 am
CLT
- TPA
1 stop5h 05m
Frontier
Deal found 3/25![Frontier logo]()
$140
This Expedia deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:09 am
TPA
- CLT
1 stop5h 37m
Multiple Airlines
Tue 4/2112:50 pm
CLT
- TPA
1 stop6h 46m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:27 pm
TPA
- GSP
Nonstop1h 40m
Breeze Airways
Thu 4/232:12 pm
GSP
- TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/20![Breeze Airways logo]()
$137
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Wed 4/2912:50 pm
CLT
- TPA
1 stop6h 46m
Spirit Airlines
Deal found 3/24![Spirit Airlines logo]()
$128
This Booking.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:27 pm
TPA
- GSP
Nonstop1h 40m
Breeze Airways
Fri 5/14:07 pm
GSP
- TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/24![Breeze Airways logo]()
$139
This Gotogate deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:32 am
TPA
- GSP
Nonstop1h 40m
Breeze Airways
Mon 5/44:07 pm
GSP
- TPA
Nonstop1h 40m
Breeze Airways
Deal found 3/23![Breeze Airways logo]()
$127
One-way flights from Tampa to South CarolinaSearch for one-way flight options from Tampa to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 25, 2026.
Search for one-way flight options from Tampa to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 25, 2026.
This Booking.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:23 pm
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 3/24![Breeze Airways logo]()
$53
This Mytrip deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:23 pm
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 3/23![Breeze Airways logo]()
$55
This Booking.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:05 am
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 3/21![Breeze Airways logo]()
$56
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:46 pm
TPA
- CHS
1 stop3h 27m
Spirit Airlines
Deal found 3/24![Spirit Airlines logo]()
$57
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:05 am
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 3/22![Breeze Airways logo]()
$58
This Cheapflightsfares deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:46 pm
TPA
- CHS
1 stop3h 27m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$59
This Booking.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:58 pm
TPA
- GSP
Nonstop1h 41m
Breeze Airways
Deal found 3/24![Breeze Airways logo]()
$59
This Priceline deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:46 pm
TPA
- CHS
1 stop3h 27m
Spirit Airlines
Deal found 3/24![Spirit Airlines logo]()
$60
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 3/22![Breeze Airways logo]()
$63
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:53 pm
TPA
- CLT
1 stop4h 56m
Spirit Airlines
Deal found 3/24![Spirit Airlines logo]()
$64
This Booking.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:29 pm
TPA
- CHS
Nonstop1h 30m
Breeze Airways
Deal found 3/20![Breeze Airways logo]()
$66
This Booking.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:56 pm
TPA
- CHS
Nonstop1h 32m
Breeze Airways
Deal found 3/25![Breeze Airways logo]()
$67
Find flight deals from Tampa to South Carolina
Keep the following information in mind while searching for Tampa to South Carolina flight deals. Data was last updated March 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $124 (Booking.com) |
One-way from | $53 (Booking.com) |
Popular in | October |
Cheapest in | January |
Average price | $231 |
Good round-trip deal | $104 or less |
Good one-way deal | $88 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from Tampa to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Fri 5/8
9:58 am-11:39 am
Nonstop1h 41m
Myrtle Beach Intl
Mon 5/11
6:14 pm-7:51 pm
Nonstop1h 37m
$138
Quickest round-trip
TampaCharleston
TPA - CHS
TPACHS
Tampa
Tue 4/14
8:05 am-9:35 am
Nonstop1h 30m
Charleston
Tue 4/21
4:03 pm-5:32 pm
Nonstop1h 29m
$148
TampaCharleston
TPA - CHS
TPACHS
Tampa
Sat 4/18
10:05 am-11:35 am
Nonstop1h 30m
Charleston
Mon 4/20
8:28 pm-9:57 pm
Nonstop1h 29m
$148
TampaGreenville
TPA - GSP
TPAGSP
Tampa
Thu 4/16
11:32 am-1:12 pm
Nonstop1h 40m
Greenville
Sun 4/19
2:12 pm-3:52 pm
Nonstop1h 40m
$148
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Fri 5/1
10:42 am-12:20 pm
Nonstop1h 38m
Myrtle Beach Intl
Mon 5/4
6:18 pm-8:00 pm
Nonstop1h 42m
$153
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Fri 5/1
10:42 am-12:20 pm
Nonstop1h 38m
Myrtle Beach Intl
Sun 5/3
6:59 pm-8:41 pm
Nonstop1h 42m
$163
TampaCharleston
TPA - CHS
TPACHS
Tampa
Wed 7/8
1:56 pm-3:28 pm
Nonstop1h 32m
Charleston
Wed 7/15
8:56 pm-10:23 pm
Nonstop1h 27m
$168
TampaCharleston
TPA - CHS
TPACHS
Tampa
Fri 4/10
8:23 pm-9:53 pm
Nonstop1h 30m
Charleston
Mon 4/13
8:28 pm-9:57 pm
Nonstop1h 29m
$198
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Thu 4/16
10:05 am-11:43 am
Nonstop1h 38m
Myrtle Beach Intl
Mon 4/20
6:18 pm-8:00 pm
Nonstop1h 42m
$198
TampaMyrtle Beach
TPA - MYR
TPAMYR
Tampa
Fri 5/8
9:58 am-11:39 am
Nonstop1h 41m
Myrtle Beach Intl
Sun 5/10
6:12 pm-7:49 pm
Nonstop1h 37m
$213
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Tampa to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Tampa with our price prediction graph.
TPA-CLT
TPA-GSP
TPA-CHS
TPA-MYR
TPA-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Tampa to South Carolina
TPA-USSC
TPA-CLT
TPA-GSP
TPA-CHS
TPA-MYR
What is the cheapest month to book a flight from Tampa to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Tampa to South Carolina (average of $46). Flying from Tampa to South Carolina in February is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TPA to SC?
Find hourly flight availability from Tampa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 25, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 28% on flights from Tampa to South Carolina by exploring options for tickets in the evening.
What is the cheapest day to fly from Tampa to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Tampa to South Carolina. Price data was last updated on March 23, 2026.
Travelers seeking maximum savings on their Tampa to South Carolina flight should consider departing on Friday afternoons when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Tampa to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 25, 2026.
See what other customers who have flown with Breeze Airways,Delta, andAllegiant Air from Tampa to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.6
Comfort
8.2
Boarding
8.3
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.6
Comfort
8.2
Boarding
8.3
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.6
Comfort
8.2
Boarding
8.3
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.6
Comfort
8.2
Boarding
8.3
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.6
Comfort
8.2
Boarding
8.3
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.6
Comfort
8.2
Boarding
8.3
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Tampa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Tampa to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Tampa to South Carolina by cabin class
Find flights from Tampa to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Tampa and South Carolina flights
Browse other Tampa and South Carolina flight options. Last updated on March 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Tampa to South Carolina flights
Consider these flights traveling from Tampa to South Carolina.
Top 5 airlines flying from Tampa to South Carolina
Discover the top 5 airlines that operate flights from Tampa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$48 | Average$99 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$79 | Average$303 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$93 | Average$186 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$94 | Average$129 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$174 | Average$340 | FlexibilityNo cancel fee | On-time71% |