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South Carolina

$264+ Cheap flights from Santa Fe (SAF) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — CHS
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Santa Fe to South Carolina

Keep the following information in mind while searching for Santa Fe to South Carolina flight deals. Data was last updated July 30, 2025.

Round-trip from

$264
(American Airlines)
From Santa Fe to South Carolina
Search Deals

Find flight deals from Santa Fe to South Carolina

Cheapest flights from Santa Fe to South Carolina
Explore the most affordable flight options available from Santa Fe to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:15 amSAF - CHS
1 stop5h 18mAmerican Airlines
Tue 10/282:24 pmCHS - SAF
1 stop8h 34mAmerican Airlines
Deal found 7/29$264
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:09 pmSAF - CLT
1 stop5h 31mAmerican Airlines
Tue 8/264:29 pmCLT - SAF
1 stop7h 30mAmerican Airlines
Deal found 7/29$344
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/269:51 amSAF - GSP
1 stop4h 58mAmerican Airlines
Sat 8/305:39 pmGSP - SAF
1 stop6h 20mAmerican Airlines
Deal found 7/29$344
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/51:23 pmSAF - CLT
1 stop7h 36mUnited Airlines
Tue 8/124:16 pmCLT - SAF
1 stop7h 42mUnited Airlines
Deal found 7/29$424
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/82:07 pmSAF - SAV
2 stops7h 52mAmerican Airlines
Mon 10/137:14 amSAV - SAF
1 stop8h 23mAmerican Airlines
Deal found 7/30$565
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/127:05 amSAF - SAV
2 stops14h 54mUnited Airlines
Sat 8/169:10 amSAV - SAF
2 stops10h 01mUnited Airlines
Deal found 7/28$575
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:19 pmSAF - HHH
2 stops23h 11mAmerican Airlines
Sat 12/134:09 pmHHH - SAF
2 stops27h 29mAmerican Airlines
Deal found 7/29$758

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Santa Fe to South Carolina that are best for you.

Fly from

Santa Fe

Fly to

South Carolina

Route

Depart

Return

Price

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 10/21

6:15 am-1:33 pm

1 stop5h 18m

Charleston

Tue 10/28

2:24 pm-8:58 pm

1 stop8h 34m

$264

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

Sat 8/23

5:09 pm-12:40 am

1 stop5h 31m

Charlotte Douglas

Tue 8/26

4:29 pm-8:47 pm

1 stop6h 18m

$344

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Tue 8/26

9:51 am-4:49 pm

1 stop4h 58m

Greenville

Sat 8/30

5:39 pm-9:59 pm

1 stop6h 20m

$344

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

Sat 8/23

7:00 am-9:37 pm

2 stops12h 37m

Charlotte Douglas

Tue 8/26

6:40 am-5:09 pm

2 stops12h 29m

$444

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Wed 10/8

2:07 pm-11:59 pm

2 stops7h 52m

Savannah/Hilton Head

Mon 10/13

7:14 am-1:37 pm

1 stop8h 23m

$565

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Tue 8/12

7:05 am-11:59 pm

2 stops14h 54m

Savannah/Hilton Head

Sat 8/16

9:10 am-5:11 pm

2 stops10h 01m

$575

Santa FeHilton Head Island

SAF - HHH

SAFHHH

Santa Fe

Wed 12/10

4:19 pm-5:30 pm

2 stops23h 11m

Hilton Head Island

Sat 12/13

4:09 pm-5:38 pm

2 stops27h 29m

$758

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Wed 11/5

6:15 am-2:31 pm

1 stop6h 16m

$290

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

Fri 11/14

12:32 pm-8:30 pm

1 stop5h 58m

$290

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Mon 8/25

2:04 pm-10:30 pm

1 stop6h 26m

$290

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 11 results
1
2

Best time to book a flight from Santa Fe to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to South Carolina

What is the cheapest month to book a flight from Santa Fe to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Santa Fe to South Carolina (average of $217). Flying from Santa Fe to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 30, 2025.
See what other customers who have flown with United Airlines and American Airlines from Santa Fe to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,896 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,896 reviews
United Airlines
7.4
Good
8,896 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,896 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Fe to South Carolina?

    Most people fly from Santa Fe (SAF) if they book a flight from Santa Fe to South Carolina. Santa Fe is conveniently located just 9.8 mi from Santa Fe’s city center.

  • What are the most popular routes from Santa Fe to South Carolina?

    When deciding which route to take from Santa Fe to South Carolina consider Santa Fe - Savannah/Hilton Head, Santa Fe - Charlotte Douglas or Santa Fe - Charleston as they are the most popular.

  • Can I find deals for flights from Santa Fe to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santa Fe to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to South Carolina.

  • Can I find deals for business class flights from Santa Fe to South Carolina?

    Yes. Cheapflights offers flight deals from Santa Fe to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Santa Fe to South Carolina (average of $217). Flying from Santa Fe to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Santa Fe to South Carolina

Discover the top airline that operate flights from Santa Fe to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$223Average$534FlexibilityNo cancel feeOn-time71%

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