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South Carolina

$284+ Cheap flights from Santa Fe (SAF) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — CHS
ene. 14 — ene. 211
mié. 1/14
mié. 1/21
1 adult, Economy
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Cheap flight deals from Santa Fe to South Carolina

Cheapest flights from Santa Fe to South Carolina
Explore the most affordable flight options available from Santa Fe to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/201:30 pmSAF - GSP
1 stop7h 59mAmerican Airlines
lun. 12/294:17 pmGSP - SAF
1 stop7h 41mAmerican Airlines
Deal found 12/14$724
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/197:00 amSAF - GSP
2 stops11h 47mUnited Airlines
lun. 12/296:45 amGSP - SAF
2 stops28h 54mUnited Airlines
Deal found 12/14$787
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/194:43 pmSAF - GSP
1 stop5h 09mAmerican Airlines
lun. 12/294:17 pmGSP - SAF
1 stop7h 41mAmerican Airlines
Deal found 12/14$802
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/201:22 pmSAF - GSP
2 stops25h 41mUnited Airlines
lun. 12/296:45 amGSP - SAF
2 stops28h 54mUnited Airlines
Deal found 12/14$888

Find flight deals from Santa Fe to South Carolina

Keep the following information in mind while searching for Santa Fe to South Carolina flight deals. Data was last updated diciembre 15, 2025.

Round-trip from

$374
(United Airlines)

One-way from

$291
(United Airlines)
From Santa Fe to South Carolina
Search Deals
One-way flight from Santa Fe to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 15, 2025.
Use the filters below to find and compare flights from Santa Fe to South Carolina that are best for you.

Fly from

Santa Fe

Fly to

South Carolina

Route

Depart

Return

Price

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

sáb. 1/17

5:18 pm-12:40 am

1 stop5h 22m

Charlotte Douglas

lun. 1/19

5:23 am-9:57 am

1 stop6h 34m

$284

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

sáb. 1/24

7:00 am-9:36 pm

2 stops12h 36m

Savannah/Hilton Head

mar. 1/27

3:54 pm-8:47 pm

1 stop6h 53m

$374

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

sáb. 1/17

10:45 am-11:48 pm

2 stops11h 03m

Greenville

mié. 1/21

10:00 am-8:47 pm

2 stops12h 47m

$379

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

sáb. 1/31

3:30 pm-10:59 pm

1 stop5h 29m

Charlotte Douglas

mié. 2/4

11:00 am-8:47 pm

2 stops11h 47m

$399

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

sáb. 1/24

10:45 am-10:46 pm

2 stops10h 01m

Savannah/Hilton Head

mié. 1/28

3:54 pm-8:47 pm

1 stop6h 53m

$399

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

dom. 1/18

7:00 am-9:36 pm

2 stops12h 36m

Savannah/Hilton Head

sáb. 1/24

3:54 pm-8:47 pm

1 stop6h 53m

$400

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

sáb. 1/17

7:00 am-5:24 pm

2 stops8h 24m

Charlotte Douglas

lun. 1/19

8:00 am-12:39 pm

1 stop6h 39m

$401

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

sáb. 1/10

7:00 am-3:05 pm

1 stop6h 05m

Charleston

mar. 1/13

4:01 pm-8:47 pm

1 stop6h 46m

$414

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

vie. 1/16

3:30 pm-10:59 pm

1 stop5h 29m

Charlotte Douglas

lun. 1/19

7:01 am-4:56 pm

2 stops11h 55m

$545

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

mié. 1/14

6:05 pm-10:45 am

2 stops14h 40m

$291

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Best time to book a flight from Santa Fe to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to South Carolina

What is the cheapest month to book a flight from Santa Fe to South Carolina?

Currently, November is the cheapest month in which you can book a flight from Santa Fe to South Carolina (average of $228). Flying from Santa Fe to South Carolina in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated diciembre 15, 2025.
See what other customers who have flown with American Airlines from Santa Fe to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,051 reviews

Overall

7.2

Crew

8.0

Food

6.5

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,051 reviews
American Airlines
7.2
Good
11,051 reviews

Overall

7.2

Crew

8.0

Food

6.5

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Fe to South Carolina?

    Most people fly from Santa Fe (SAF) if they book a flight from Santa Fe to South Carolina. Santa Fe is conveniently located just 9.8 mi from Santa Fe’s city center.

  • How long is the flight from Santa Fe to South Carolina?

    A quick flight from Santa Fe to South Carolina can take about 5h 22m. American Airlines provides one of the quickest options available for as low as $284. Airlines will cover a distance of 1411 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Santa Fe to South Carolina?

    When deciding which route to take from Santa Fe to South Carolina consider Santa Fe - Greenville, Santa Fe - Charleston or Santa Fe - Savannah/Hilton Head as they are the most popular.

  • Can I find deals for flights from Santa Fe to South Carolina that include hotel bookings?

    Yes. In addition to deals on Santa Fe to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to South Carolina.

  • Can I find deals for business class flights from Santa Fe to South Carolina?

    Yes. Cheapflights offers flight deals from Santa Fe to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to South Carolina?

    Currently, November is the cheapest month in which you can book a flight from Santa Fe to South Carolina (average of $228). Flying from Santa Fe to South Carolina in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Santa Fe to South Carolina

Discover the top airline that operate flights from Santa Fe to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$264Average$523FlexibilityNo cancel feeOn-time71%

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