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South Carolina

$325+ Cheap flights from Rome (ROM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — CHS
dic. 6 — dic. 131
sáb. 12/6
sáb. 12/13
1 adult, Economy
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Cheap flight deals from Rome to South Carolina

Keep the following information in mind while searching for Rome to South Carolina flight deals. Data was last updated noviembre 6, 2025.

Round-trip from

$532
(Vliegwinkel)

One-way from

$325
(Kiwi.com)
From Rome (ROM) to South Carolina
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One-way flight from Rome (ROM) to South Carolina
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Find flight deals from Rome to South Carolina

Cheapest flights from Rome to South Carolina
Explore the most affordable flight options available from Rome to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 6, 2025.

This Vliegwinkel deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Vliegwinkel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/2010:15 amFCO - CLT
1 stop18h 53mMultiple Airlines
mié. 12/35:35 amCLT - FCO
1 stop19h 30mMultiple Airlines
Deal found 11/5$532
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/237:10 pmFCO - CLT
1 stop34h 03mMultiple Airlines
sáb. 12/612:59 pmCLT - FCO
1 stop19h 31mMultiple Airlines
Deal found 11/4$534
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/127:10 pmFCO - CLT
1 stop22h 54mMultiple Airlines
jue. 1/88:46 pmCLT - FCO
2 stops35h 44mMultiple Airlines
Deal found 11/6$548
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/137:10 pmFCO - CLT
1 stop22h 54mMultiple Airlines
jue. 1/88:46 pmCLT - FCO
2 stops35h 44mMultiple Airlines
Deal found 11/6$624
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/137:00 amFCO - CLT
1 stop15h 55mLufthansa
jue. 1/87:44 pmCLT - FCO
2 stops16h 31mLufthansa
Deal found 11/6$670
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/137:00 amFCO - CLT
1 stop15h 55mLufthansa
dom. 12/1410:43 amCLT - FCO
1 stop15h 02mLufthansa
Deal found 11/5$680
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/1511:00 amFCO - CHS
1 stop14h 00mUnited Airlines
dom. 11/236:15 amCHS - FCO
1 stop19h 30mUnited Airlines
Deal found 11/6$721
This Ovago deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/1511:00 amFCO - CHS
1 stop14h 00mLufthansa
dom. 11/2311:14 amCHS - FCO
1 stop14h 41mLufthansa
Deal found 11/5$780
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/2010:30 amFCO - GSP
1 stop19h 19mLufthansa
vie. 1/22:50 pmGSP - FCO
1 stop11h 40mLufthansa
Deal found 11/5$943
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/2011:00 amFCO - GSP
1 stop14h 16mUnited Airlines
vie. 1/28:34 amGSP - FCO
2 stops17h 56mUnited Airlines
Deal found 11/5$957
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/2111:00 amFCO - GSP
2 stops30h 54mUnited Airlines
dom. 12/289:40 amGSP - FCO
2 stops41h 15mUnited Airlines
Deal found 11/6$972
This Finnair deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/2311:00 amFCO - GSP
1 stop15h 39mMultiple Airlines
dom. 12/2810:36 amGSP - FCO
1 stop16h 24mMultiple Airlines
Deal found 11/6$985

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Rome to South Carolina that are best for you.

Fly from

Rome

Fly to

South Carolina

Route

Depart

Return

Price

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

dom. 11/23

7:10 pm-11:13 pm

1 stop34h 03m

Charlotte Douglas

sáb. 12/6

12:59 pm-2:30 pm

1 stop19h 31m

$534

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

vie. 12/12

7:10 pm-12:04 pm

1 stop22h 54m

Charlotte Douglas

jue. 1/8

8:46 pm-2:30 pm

2 stops35h 44m

$548

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

jue. 11/20

10:15 am-8:49 am

2 stops28h 34m

Charlotte Douglas

mié. 12/3

5:35 am-11:45 am

1 stop24h 10m

$591

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

vie. 2/6

12:45 pm-5:13 pm

2 stops34h 28m

Charleston

dom. 2/8

4:45 pm-4:25 pm

2 stops17h 40m

$670

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

sáb. 12/13

7:00 am-4:55 pm

1 stop15h 55m

Charlotte Douglas

jue. 1/8

7:44 pm-6:15 pm

2 stops16h 31m

$676

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

mié. 4/1

1:10 pm-5:40 pm

Nonstop10h 30m

Charlotte Douglas

dom. 4/5

11:45 pm-11:55 pm

1 stop18h 10m

$693

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

dom. 11/23

7:05 am-6:51 pm

2 stops17h 46m

Charlotte Douglas

sáb. 12/6

2:47 pm-8:30 am

1 stop11h 43m

$693

RomeGreenville

FCO - GSP

FCOGSP

Rome Fiumicino

vie. 2/6

7:05 am-7:29 pm

2 stops18h 24m

Greenville

dom. 2/8

10:51 am-7:55 am

2 stops15h 04m

$694

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

sáb. 12/13

7:05 am-8:57 pm

2 stops19h 52m

Charlotte Douglas

jue. 1/8

10:44 am-2:00 pm

2 stops21h 16m

$694

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

mié. 4/1

10:00 am-11:29 pm

2 stops19h 29m

Charlotte Douglas

dom. 4/5

6:00 am-8:15 am

1 stop20h 15m

$694

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 32 results
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Best time to book a flight from Rome to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Rome to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rome to South Carolina?

    Airlines like KLM, United Airlines, and Lufthansa fly from Rome to South Carolina in about 18h 24m. The time it takes to get you to your destination can typically vary by up to 16h 04m. There are 4869 mi between Rome and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Rome to South Carolina?

    When deciding which route to take from Rome to South Carolina consider Rome Fiumicino - Charlotte Douglas, Rome Fiumicino - Charleston or Rome Fiumicino - Greenville as they are the most popular.

  • Can I find deals for flights from Rome to South Carolina that include hotel bookings?

    Yes. In addition to deals on Rome to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to South Carolina.

  • Can I find deals for business class flights from Rome to South Carolina?

    Yes. Cheapflights offers flight deals from Rome to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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