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South Carolina

$344+ Cheap flights from Rome (ROM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — CHS
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from Rome to South Carolina

Keep the following information in mind while searching for Rome to South Carolina flight deals. Data was last updated November 13, 2025.

Round-trip from

$682
(KLM)

One-way from

$344
(Kiwi.com)
From Rome (ROM) to South Carolina
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One-way flight from Rome (ROM) to South Carolina
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Find flight deals from Rome to South Carolina

Cheapest flights from Rome to South Carolina
Explore the most affordable flight options available from Rome to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/198:55 pmFCO - CLT
2 stops41h 44mMultiple Airlines
Tue 12/210:17 amCLT - FCO
1 stop22h 13mMultiple Airlines
Deal found 11/11$687
This lol.travel deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/191:15 pmFCO - CLT
2 stops37h 42mAir Canada
Tue 12/29:30 amCLT - FCO
2 stops41h 55mAir Canada
Deal found 11/11$689
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2311:00 amFCO - CLT
1 stop19h 18mAmerican Airlines
Sat 12/66:25 pmCLT - FCO
1 stop13h 05mAmerican Airlines
Deal found 11/11$702
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:10 amFCO - CHS
2 stops19h 00mDelta
Sun 11/306:28 pmCHS - FCO
2 stops14h 47mDelta
Deal found 11/11$705
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1912:20 pmFCO - CLT
1 stop33h 35mAmerican Airlines
Tue 12/26:25 pmCLT - FCO
1 stop19h 15mAmerican Airlines
Deal found 11/11$706
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2612:20 pmFCO - CHS
2 stops17h 22mUnited Airlines
Sun 11/306:00 amCHS - FCO
1 stop22h 55mUnited Airlines
Deal found 11/11$710
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2312:55 pmFCO - CLT
2 stops17h 03mUnited Airlines
Sat 12/611:13 amCLT - FCO
1 stop14h 42mUnited Airlines
Deal found 11/12$716
This Mytrip deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/235:55 amFCO - CLT
3 stops32h 54mMultiple Airlines
Sat 12/612:59 pmCLT - FCO
1 stop19h 31mMultiple Airlines
Deal found 11/13$719
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:10 amFCO - CHS
2 stops20h 32mDelta
Sun 11/2312:53 pmCHS - FCO
2 stops14h 02mDelta
Deal found 11/11$901
This KLM deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:00 pmFCO - CHS
1 stop14h 32mKLM
Sun 11/236:00 amCHS - FCO
1 stop19h 05mKLM
Deal found 11/11$922
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/267:30 amFCO - CHS
2 stops17h 42mAmerican Airlines
Sun 11/306:32 pmCHS - FCO
2 stops13h 58mAmerican Airlines
Deal found 11/11$927
This Cheapflightsfares deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2010:30 amFCO - GSP
1 stop19h 19mLufthansa
Fri 1/22:50 pmGSP - FCO
1 stop11h 40mLufthansa
Deal found 11/11$947

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Rome to South Carolina that are best for you.

Fly from

Rome

Fly to

South Carolina

Route

Depart

Return

Price

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Fri 2/6

12:45 pm-5:13 pm

2 stops34h 28m

Charleston

Sun 2/8

1:12 pm-11:55 am

2 stops16h 43m

$682

RomeGreenville

FCO - GSP

FCOGSP

Rome Fiumicino

Fri 2/6

7:05 am-7:29 pm

2 stops18h 24m

Greenville

Sun 2/8

10:51 am-7:55 am

2 stops15h 04m

$698

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 4/1

1:10 pm-5:40 pm

Nonstop10h 30m

Charlotte Douglas

Sun 4/5

11:45 pm-7:15 pm

1 stop13h 30m

$698

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Fri 2/6

7:05 am-7:04 pm

2 stops17h 59m

Charleston

Sun 2/8

2:58 pm-8:30 am

1 stop11h 32m

$698

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 4/1

1:20 pm-11:58 pm

2 stops16h 38m

Charlotte Douglas

Sun 4/5

5:28 pm-7:55 am

1 stop32h 27m

$703

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Sun 11/23

11:00 am-12:07 pm

1 stop31h 07m

Charlotte Douglas

Sat 12/6

6:25 pm-1:30 pm

1 stop13h 05m

$703

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Wed 11/26

6:10 am-7:10 pm

2 stops19h 00m

Charleston

Sun 11/30

6:28 pm-3:15 pm

2 stops14h 47m

$705

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 4/1

8:10 am-4:45 pm

1 stop14h 35m

Charlotte Douglas

Sun 4/5

10:40 am-7:55 am

1 stop15h 15m

$706

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 4/1

6:50 am-9:00 pm

2 stops20h 10m

Charlotte Douglas

Sun 4/5

4:55 pm-9:15 am

2 stops34h 20m

$707

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Wed 11/26

12:20 pm-11:42 pm

2 stops17h 22m

Charleston

Sun 11/30

6:00 am-10:55 am

1 stop22h 55m

$710

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 28 results
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Best time to book a flight from Rome to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Rome to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rome to South Carolina?

    Airlines like KLM, United Airlines, and American Airlines fly from Rome to South Carolina in about 10h 30m. The time it takes to get you to your destination can typically vary by up to 23h 58m. There are 4798 mi between Rome and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Rome to South Carolina?

    When deciding which route to take from Rome to South Carolina consider Rome Fiumicino - Charlotte Douglas, Rome Fiumicino - Charleston or Rome Fiumicino - Greenville as they are the most popular.

  • Can I find deals for flights from Rome to South Carolina that include hotel bookings?

    Yes. In addition to deals on Rome to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to South Carolina.

  • Can I find deals for business class flights from Rome to South Carolina?

    Yes. Cheapflights offers flight deals from Rome to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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