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South Carolina

$313+ Cheap flights from Rome (ROM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — CHS
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Rome to South Carolina

Keep the following information in mind while searching for Rome to South Carolina flight deals. Data was last updated October 16, 2025.

Round-trip from

$558
(Kiwi.com)

One-way from

$313
(Kiwi.com)
From Rome (ROM) to South Carolina
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One-way flight from Rome (ROM) to South Carolina
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Find flight deals from Rome to South Carolina

Cheapest flights from Rome to South Carolina
Explore the most affordable flight options available from Rome to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:10 pmFCO - CLT
1 stop31h 15mMultiple Airlines
Thu 12/49:00 amCLT - FCO
2 stops23h 30mMultiple Airlines
Deal found 10/16$558
This Mytrip deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:00 amFCO - CLT
2 stops31h 49mMultiple Airlines
Wed 12/310:17 amCLT - FCO
1 stop22h 13mMultiple Airlines
Deal found 10/15$571
This Trip.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1110:15 amFCO - CLT
1 stop17h 53mMultiple Airlines
Tue 11/255:35 amCLT - FCO
1 stop19h 30mMultiple Airlines
Deal found 10/16$641
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:10 pmFCO - CLT
1 stop30h 28mMultiple Airlines
Sat 11/84:55 pmCLT - FCO
1 stop15h 35mMultiple Airlines
Deal found 10/16$645
This lol.travel deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/219:45 amFCO - CLT
2 stops17h 12mAir Canada
Thu 12/45:05 pmCLT - FCO
2 stops34h 20mAir Canada
Deal found 10/16$657
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:00 amFCO - CLT
1 stop15h 55mLufthansa
Tue 11/252:50 pmCLT - FCO
2 stops15h 35mLufthansa
Deal found 10/16$675
This British Airways deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1211:00 amFCO - CLT
1 stop18h 12mBritish Airways
Tue 1/138:20 pmCLT - FCO
1 stop14h 35mBritish Airways
Deal found 10/16$682
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2312:10 pmFCO - CLT
Nonstop11h 10mAmerican Airlines
Thu 10/3011:59 pmCLT - FCO
1 stop17h 51mAmerican Airlines
Deal found 10/16$686
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1212:20 pmFCO - CLT
1 stop31h 45mAmerican Airlines
Sun 11/1610:55 pmCLT - FCO
1 stop30h 30mAmerican Airlines
Deal found 10/15$688
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:10 pmFCO - CHS
1 stop29h 31mMultiple Airlines
Tue 11/46:11 pmCHS - FCO
1 stop14h 19mMultiple Airlines
Deal found 10/15$690
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1510:05 amFCO - CHS
2 stops16h 27mDelta
Sun 11/236:00 amCHS - FCO
1 stop21h 45mDelta
Deal found 10/15$721
This Expedia deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3110:05 amFCO - CHS
2 stops36h 49mKLM
Tue 11/411:29 amCHS - FCO
2 stops15h 41mKLM
Deal found 10/15$723

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Rome to South Carolina that are best for you.

Fly from

Rome

Fly to

South Carolina

Route

Depart

Return

Price

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Thu 11/20

7:00 am-8:49 am

2 stops31h 49m

Charlotte Douglas

Wed 12/3

10:17 am-2:30 pm

1 stop22h 13m

$571

RomeGreenville

FCO - GSP

FCOGSP

Rome Fiumicino

Fri 2/13

1:10 pm-11:12 pm

2 stops16h 02m

Greenville

Tue 2/17

8:41 pm-7:40 pm

2 stops16h 59m

$681

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Fri 12/12

11:00 am-11:12 pm

1 stop18h 12m

Charlotte Douglas

Tue 1/13

8:20 pm-4:55 pm

1 stop14h 35m

$682

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Fri 2/6

12:45 pm-4:47 pm

2 stops34h 02m

Charleston

Sun 2/8

12:15 pm-11:55 am

2 stops17h 40m

$683

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Fri 10/31

6:10 pm-6:41 pm

1 stop29h 31m

Charleston

Tue 11/4

6:11 pm-2:30 pm

1 stop14h 19m

$690

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Fri 12/12

1:35 pm-8:57 pm

2 stops37h 22m

Charlotte Douglas

Fri 1/16

9:30 am-9:25 am

2 stops17h 55m

$694

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 11/12

7:05 am-10:04 pm

2 stops20h 59m

Charlotte Douglas

Sun 11/16

1:56 pm-7:55 am

1 stop11h 59m

$701

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Fri 2/6

7:05 am-7:04 pm

2 stops17h 59m

Charleston

Sun 2/8

2:58 pm-8:30 am

1 stop11h 32m

$701

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Mon 12/15

7:05 am-10:32 am

2 stops33h 27m

Charlotte Douglas

Thu 1/15

9:55 am-8:30 am

1 stop16h 35m

$704

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 12/10

1:30 pm-10:32 am

2 stops27h 02m

Charlotte Douglas

Thu 1/15

9:55 am-8:30 am

1 stop16h 35m

$704

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/16

Showing 1-10 of 36 results
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Best time to book a flight from Rome to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Rome to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rome to South Carolina?

    Airlines like American Airlines, British Airways, and KLM fly from Rome to South Carolina in about 16h 02m. The time it takes to get you to your destination can typically vary by up to 18h. There are 4869 mi between Rome and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Rome to South Carolina?

    When deciding which route to take from Rome to South Carolina consider Rome Fiumicino - Charlotte Douglas, Rome Fiumicino - Charleston or Rome Fiumicino - Greenville as they are the most popular.

  • Can I find deals for flights from Rome to South Carolina that include hotel bookings?

    Yes. In addition to deals on Rome to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to South Carolina.

  • Can I find deals for business class flights from Rome to South Carolina?

    Yes. Cheapflights offers flight deals from Rome to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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