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South Carolina

$299+ Cheap flights from Rome (ROM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — CHS
Feb 18 — Feb 251
Wed 2/18
Wed 2/25
1 adult, Economy
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Cheap flight deals from Rome to South Carolina

Keep the following information in mind while searching for Rome to South Carolina flight deals. Data was last updated January 19, 2026.

Round-trip from

$652
(American Airlines)

One-way from

$299
(Kiwi.com)
From Rome (ROM) to South Carolina
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One-way flight from Rome (ROM) to South Carolina
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Find flight deals from Rome to South Carolina

Cheapest flights from Rome to South Carolina
Explore the most affordable flight options available from Rome to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 19, 2026.

This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:15 pm
FCO
-
CLT
Nonstop10h 45m
American Airlines
Fri 4/178:15 pm
CLT
-
FCO
1 stop13h 15m
American Airlines
Deal found 1/18$652
This Finnair deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2510:40 am
FCO
-
CLT
2 stops26h 55m
Multiple Airlines
Mon 4/138:15 pm
CLT
-
FCO
1 stop12h 55m
Multiple Airlines
Deal found 1/19$653
This American Airlines deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:15 pm
FCO
-
GSP
1 stop27h 40m
American Airlines
Mon 9/288:40 pm
GSP
-
FCO
2 stops16h 35m
American Airlines
Deal found 1/17$657
This British Airways deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/131:10 pm
FCO
-
CLT
1 stop14h 05m
British Airways
Thu 2/2611:00 pm
CLT
-
FCO
1 stop17h 50m
British Airways
Deal found 1/18$659
This British Airways deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/251:10 pm
FCO
-
CLT
1 stop15h 15m
British Airways
Mon 4/138:15 pm
CLT
-
FCO
1 stop13h 45m
British Airways
Deal found 1/19$660
This American Airlines deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2911:10 am
FCO
-
CLT
1 stop34h 55m
American Airlines
Mon 2/26:30 pm
CLT
-
FCO
1 stop12h 20m
American Airlines
Deal found 1/17$663
This Finnair deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1710:40 am
FCO
-
CLT
2 stops27h 55m
Finnair
Tue 2/2411:31 am
CLT
-
FCO
2 stops24h 24m
Finnair
Deal found 1/18$664
This American Airlines deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/67:30 am
FCO
-
CHS
2 stops20h 13m
American Airlines
Mon 2/97:20 pm
CHS
-
FCO
2 stops18h 15m
American Airlines
Deal found 1/17$666
This British Airways deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:15 pm
FCO
-
CHS
1 stop13h 31m
British Airways
Fri 4/1711:04 am
CHS
-
FCO
1 stop18h 16m
British Airways
Deal found 1/18$669
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/47:05 am
FCO
-
CHS
2 stops22h 39m
United Airlines
Sun 2/82:58 pm
CHS
-
FCO
1 stop11h 32m
United Airlines
Deal found 1/19$679
This Gurufare deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:30 am
FCO
-
CLT
2 stops18h 44m
Multiple Airlines
Sun 2/2211:00 pm
CLT
-
FCO
1 stop12h 50m
Multiple Airlines
Deal found 1/18$681
This Trip.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1310:30 am
FCO
-
CLT
1 stop19h 29m
Multiple Airlines
Thu 2/269:21 am
CLT
-
FCO
2 stops19h 39m
Multiple Airlines
Deal found 1/18$683

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 19, 2026.
Use the filters below to find and compare flights from Rome to South Carolina that are best for you.

Fly from

Rome

Fly to

South Carolina

Route

Depart

Return

Price

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Tue 4/7

2:15 pm-7:00 pm

Nonstop10h 45m

Charlotte Douglas

Fri 4/17

8:15 pm-3:30 pm

1 stop13h 15m

$652

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Tue 2/17

10:40 am-8:35 am

2 stops27h 55m

Charlotte Douglas

Tue 2/24

11:00 pm-9:55 pm

1 stop16h 55m

$653

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 3/25

10:40 am-8:35 am

2 stops26h 55m

Charlotte Douglas

Mon 4/13

8:15 pm-3:10 pm

1 stop12h 55m

$653

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Fri 2/13

1:10 pm-9:15 pm

1 stop14h 05m

Charlotte Douglas

Thu 2/26

11:00 pm-10:50 pm

1 stop17h 50m

$659

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Fri 2/13

7:05 am-11:59 pm

2 stops22h 54m

Charlotte Douglas

Thu 2/26

9:21 am-11:00 am

2 stops19h 39m

$659

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 3/25

1:10 pm-11:25 pm

1 stop15h 15m

Charlotte Douglas

Mon 4/13

8:15 pm-3:10 pm

1 stop12h 55m

$660

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Sun 2/15

1:10 pm-9:15 pm

1 stop14h 05m

Charlotte Douglas

Sun 2/22

11:00 pm-9:55 pm

1 stop16h 55m

$660

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Tue 2/17

1:10 pm-11:32 pm

1 stop16h 22m

Charlotte Douglas

Tue 2/24

6:25 pm-7:40 pm

1 stop19h 15m

$660

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Tue 2/17

10:40 am-8:35 am

2 stops27h 55m

Charlotte Douglas

Tue 2/24

11:31 am-5:55 pm

2 stops24h 24m

$664

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Thu 1/29

7:30 am-8:34 pm

2 stops19h 04m

Charlotte Douglas

Mon 2/2

6:08 pm-2:55 pm

2 stops14h 47m

$666

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/17

Showing 1-10 of 44 results
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Best time to book a flight from Rome to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Rome to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rome to South Carolina?

    Airlines like British Airways, American Airlines, and United Airlines fly from Rome to South Carolina in about 14h 05m. The time it takes to get you to your destination can typically vary by up to 12h 42m. There are 4798 mi between Rome and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Rome to South Carolina?

    When deciding which route to take from Rome to South Carolina consider Rome Fiumicino - Charlotte Douglas, Rome Fiumicino - Charleston or Rome Fiumicino - Greenville as they are the most popular.

  • Can I find deals for flights from Rome to South Carolina that include hotel bookings?

    Yes. In addition to deals on Rome to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to South Carolina.

  • Can I find deals for business class flights from Rome to South Carolina?

    Yes. Cheapflights offers flight deals from Rome to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Rome to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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