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$292+ Cheap flights from Rome (ROM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — CHS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Rome to South Carolina

Keep the following information in mind while searching for Rome to South Carolina flight deals. Data was last updated September 15, 2025.

Round-trip from

$577
(Kiwi.com)

One-way from

$292
(Kiwi.com)
From Rome (ROM) to South Carolina
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One-way flight from Rome (ROM) to South Carolina
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Find flight deals from Rome to South Carolina

Cheapest flights from Rome to South Carolina
Explore the most affordable flight options available from Rome to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:05 pmFCO - CLT
1 stop24h 59mMultiple Airlines
Wed 10/226:00 amCLT - FCO
1 stop26h 30mMultiple Airlines
Deal found 9/13$576
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2411:55 pmFCO - CHS
2 stops24h 46mMultiple Airlines
Fri 11/711:40 amCHS - FCO
1 stop20h 50mMultiple Airlines
Deal found 9/15$577
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:10 amFCO - CLT
2 stops17h 25mUnited Airlines
Wed 10/156:30 amCLT - FCO
2 stops19h 05mUnited Airlines
Deal found 9/13$591
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/121:30 pmFCO - CLT
2 stops16h 28mUnited Airlines
Sun 11/1610:43 amCLT - FCO
1 stop15h 02mUnited Airlines
Deal found 9/14$592
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:10 amFCO - CHS
2 stops17h 51mUnited Airlines
Sun 10/56:00 amCHS - FCO
2 stops21h 15mUnited Airlines
Deal found 9/15$592
This lol.travel deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/911:30 amFCO - CLT
2 stops33h 02mAir Canada
Wed 10/228:30 amCLT - FCO
2 stops18h 45mAir Canada
Deal found 9/14$593
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2512:50 pmFCO - CHS
2 stops27h 18mUnited Airlines
Fri 11/76:15 amCHS - FCO
2 stops20h 15mUnited Airlines
Deal found 9/15$604
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/93:20 pmFCO - CLT
1 stop14h 39mUnited Airlines
Wed 10/227:46 pmCLT - FCO
1 stop11h 19mUnited Airlines
Deal found 9/15$608
This lol.travel deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:20 amFCO - CLT
1 stop16h 40mBritish Airways
Sat 10/1111:40 pmCLT - FCO
1 stop13h 20mBritish Airways
Deal found 9/14$644
This lol.travel deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/912:10 pmFCO - CLT
Nonstop11h 10mBritish Airways
Wed 10/226:45 pmCLT - FCO
Nonstop9h 05mBritish Airways
Deal found 9/15$646
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:10 amFCO - CHS
2 stops37h 53mUnited Airlines
Fri 11/711:14 amCHS - FCO
2 stops15h 16mUnited Airlines
Deal found 9/15$680
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:20 pmFCO - CHS
2 stops26h 48mUnited Airlines
Wed 11/57:45 pmCHS - FCO
1 stop30h 45mUnited Airlines
Deal found 9/14$693

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Rome to South Carolina that are best for you.

Fly from

Rome

Fly to

South Carolina

Route

Depart

Return

Price

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Thu 10/9

7:05 pm-2:04 pm

1 stop24h 59m

Charlotte Douglas

Wed 10/22

6:00 am-2:30 pm

1 stop26h 30m

$576

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 10/8

7:10 am-6:35 pm

2 stops17h 25m

Charlotte Douglas

Wed 10/15

6:30 am-7:35 am

2 stops19h 05m

$591

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Thu 10/9

7:10 am-11:59 pm

2 stops22h 49m

Charlotte Douglas

Wed 10/22

10:34 am-8:15 am

1 stop15h 41m

$591

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 11/12

7:05 am-9:59 pm

2 stops20h 54m

Charlotte Douglas

Sun 11/16

2:50 pm-10:55 am

2 stops14h 05m

$591

RomeGreenville

FCO - GSP

FCOGSP

Rome Fiumicino

Fri 2/13

9:45 am-8:55 pm

2 stops17h 10m

Greenville

Tue 2/17

12:00 pm-7:55 am

1 stop13h 55m

$592

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Wed 10/1

7:10 am-7:01 pm

2 stops17h 51m

Charleston

Sun 10/5

6:00 am-9:15 am

2 stops21h 15m

$592

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Sat 10/25

12:50 pm-10:08 am

2 stops27h 18m

Charleston

Fri 11/7

6:15 am-8:30 am

2 stops20h 15m

$604

RomeGreenville

FCO - GSP

FCOGSP

Rome Fiumicino

Fri 2/13

11:00 am-7:24 pm

1 stop14h 24m

Greenville

Tue 2/17

2:55 pm-8:30 am

1 stop11h 35m

$608

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Fri 10/24

7:10 am-3:03 pm

2 stops37h 53m

Charleston

Fri 11/7

11:14 am-8:30 am

2 stops15h 16m

$680

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Wed 10/29

12:20 pm-10:08 am

2 stops26h 48m

Charleston

Wed 11/5

10:00 am-8:55 am

2 stops16h 55m

$693

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 27 results
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Best time to book a flight from Rome to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Rome to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rome to South Carolina?

    Airlines like United Airlines and Brussels Airlines fly from Rome to South Carolina in about 14h 24m. The time it takes to get you to your destination can typically vary by up to 3h 01m. There are 4869 mi between Rome and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Rome to South Carolina?

    When deciding which route to take from Rome to South Carolina consider Rome Fiumicino - Charlotte Douglas, Rome Fiumicino - Charleston or Rome Fiumicino - Greenville as they are the most popular.

  • Can I find deals for flights from Rome to South Carolina that include hotel bookings?

    Yes. In addition to deals on Rome to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to South Carolina.

  • Can I find deals for business class flights from Rome to South Carolina?

    Yes. Cheapflights offers flight deals from Rome to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rome to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Rome to South Carolina (average of $217). Flying from Rome to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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