How long is the flight from Rome to South Carolina?

Airlines like American Airlines and United Airlines fly from Rome to South Carolina in about 17h 14m. The time it takes to get you to your destination can typically vary by up to 10h 15m. There are 4855 mi between Rome and South Carolina. This flight may include one or multiple stops.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

What are the most popular routes from Rome to South Carolina?

When deciding which route to take from Rome to South Carolina consider Rome Fiumicino - Charlotte Douglas, Rome Fiumicino - Greenville or Rome Fiumicino - Charleston as they are the most popular.

What is the cheapest time of day to fly from ROM to SC?

When flying from Rome to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from Rome to South Carolina that include hotel bookings?

Yes. In addition to deals on Rome to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Rome to South Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to South Carolina.

Can I find deals for business class flights from Rome to South Carolina?

Yes. Cheapflights offers flight deals from Rome to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$282+ Flights from Rome to South Carolina

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Cheap flight deals from Rome to South Carolina

Cheapest flights from Rome to South Carolina
Explore the most affordable flight options available from Rome to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Tue 12/301:10 pmFCO - CLT

1 stop26h 25mAmerican Airlines

Mon 1/128:25 pmCLT - FCO

1 stop17h 10mAmerican Airlines

Deal found 12/26

$912

Tue 12/3010:05 amFCO - CLT

2 stops17h 45mDelta

Mon 1/122:30 pmCLT - FCO

2 stops18h 45mDelta

Deal found 12/26

$1,017

Tue 12/303:45 pmFCO - CLT

3 stops44h 48mMultiple Airlines

Mon 1/128:36 amCLT - FCO

3 stops45h 39mMultiple Airlines

Deal found 12/26

$15,562

Best flights from Rome to South Carolina
Discover carefully curated flight deals from Rome to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Fri 2/131:10 pmFCO - CLT

1 stop14h 08mMultiple Airlines

Thu 2/268:20 pmCLT - FCO

1 stop16h 50mMultiple Airlines

Deal found 12/27

$646

Fri 2/131:10 pmFCO - CLT

1 stop27h 29mAmerican Airlines

Thu 2/2611:00 pmCLT - FCO

1 stop14h 10mAmerican Airlines

Deal found 12/26

$663

Fri 2/131:10 pmFCO - CLT

1 stop14h 08mBritish Airways

Thu 2/268:02 pmCLT - FCO

2 stops17h 08mBritish Airways

Deal found 12/26

$664

Fri 2/277:05 amFCO - CHS

2 stops17h 14mUnited Airlines

Mon 3/25:05 pmCHS - FCO

1 stop32h 40mUnited Airlines

Deal found 12/25

$735

Mon 2/911:00 amFCO - CHS

1 stop14h 04mLufthansa

Mon 2/162:48 pmCHS - FCO

2 stops16h 37mLufthansa

Deal found 12/26

$755

Mon 2/912:40 pmFCO - CHS

1 stop14h 17mKLM

Mon 2/163:07 pmCHS - FCO

1 stop13h 23mKLM

Deal found 12/26

$772

Sat 4/42:05 pmFCO - CLT

1 stop31h 00mMultiple Airlines

Mon 4/135:50 pmCLT - FCO

1 stop20h 25mMultiple Airlines

Deal found 12/26

$650

Wed 3/251:10 pmFCO - CLT

1 stop15h 15mBritish Airways

Mon 4/135:50 pmCLT - FCO

1 stop13h 05mBritish Airways

Deal found 12/26

$665

Thu 1/2911:10 amFCO - CLT

1 stop34h 55mAmerican Airlines

Mon 2/26:08 pmCLT - FCO

2 stops14h 47mAmerican Airlines

Deal found 12/26

$666

Tue 2/1010:40 amFCO - CLT

2 stops28h 00mMultiple Airlines

Tue 2/1711:05 pmCLT - FCO

1 stop16h 50mMultiple Airlines

Deal found 12/26

$658

Mon 2/97:05 amFCO - CHS

2 stops37h 43mUnited Airlines

Mon 2/162:48 pmCHS - FCO

2 stops17h 12mUnited Airlines

Deal found 12/26

$735

Mon 2/911:15 amFCO - CHS

2 stops32h 47mMultiple Airlines

Mon 2/166:00 amCHS - FCO

3 stops20h 40mMultiple Airlines

Deal found 12/26

$899

Mon 5/49:00 amFCO - GSP

1 stop14h 28mKLM

Mon 5/47:59 pmGSP - FCO

1 stop29h 36mKLM

Deal found 12/26

$1,813

Last-minute flights from Rome to South Carolina
Discover last-minute flight deals from Rome to South Carolina. Data last updated December 28, 2025 and is based on user searches.

Tue 12/301:10 pmFCO - CLT

1 stop26h 25mAmerican Airlines

Mon 1/128:25 pmCLT - FCO

1 stop17h 10mAmerican Airlines

Deal found 12/26

$912

Tue 12/3010:05 amFCO - CLT

2 stops17h 45mDelta

Mon 1/122:30 pmCLT - FCO

2 stops18h 45mDelta

Deal found 12/26

$1,017

Fri 1/29:45 amFCO - CLT

2 stops39h 10mUnited Airlines

Sat 1/177:01 amCLT - FCO

2 stops19h 29mUnited Airlines

Deal found 12/28

$2,281

Mon 1/1212:00 pmFCO - CLT

1 stop34h 05mAmerican Airlines

Fri 1/1611:15 pmCLT - FCO

1 stop16h 40mAmerican Airlines

Deal found 12/27

$930

Mon 1/1212:00 pmFCO - CLT

1 stop34h 05mIberia

Fri 1/168:25 pmCLT - FCO

2 stops15h 45mIberia

Deal found 12/27

$944

Mon 1/1211:15 amFCO - CLT

2 stops39h 42mAir Canada

Fri 1/167:50 amCLT - FCO

2 stops24h 10mAir Canada

Deal found 12/27

$995

Sun 1/255:50 pmFCO - CLT

1 stop26h 25mMultiple Airlines

Sun 2/111:15 pmCLT - FCO

1 stop16h 40mMultiple Airlines

Deal found 12/25

$669

Sun 1/257:30 amFCO - CLT

2 stops18h 44mAmerican Airlines

Sun 2/16:30 pmCLT - FCO

1 stop14h 00mAmerican Airlines

Deal found 12/25

$676

Thu 1/2911:10 amFCO - CLT

1 stop34h 55mAmerican Airlines

Mon 2/26:08 pmCLT - FCO

2 stops14h 47mAmerican Airlines

Deal found 12/27

$666

One-way flights from Rome to South Carolina
Search for one-way flight options from Rome to South Carolina. Find affordable one-way fares based on user searches. Data last updated December 28, 2025.

Thu 5/217:05 pmFCO - CLT

1 stop31h 28mMultiple Airlines

Deal found 12/27

$282

Wed 2/255:45 amFCO - CLT

2 stops42h 05mMultiple Airlines

Deal found 12/26

$352

Sun 1/258:25 amFCO - CLT

3 stops56h 15mMultiple Airlines

Deal found 12/27

$361

Thu 1/228:25 amFCO - CLT

3 stops55h 30mMultiple Airlines

Deal found 12/26

$363

Wed 1/285:45 amFCO - CLT

2 stops34h 38mMultiple Airlines

Deal found 12/27

$368

Sun 3/18:25 amFCO - CLT

3 stops55h 52mMultiple Airlines

Deal found 12/26

$371

Fri 1/238:25 amFCO - CLT

3 stops55h 05mMultiple Airlines

Deal found 12/27

$386

Tue 3/241:10 pmFCO - CHS

1 stop26h 07mMultiple Airlines

Deal found 12/26

$462

Mon 5/111:10 pmFCO - CHS

1 stop16h 18mMultiple Airlines

Deal found 12/26

$464

Mon 3/236:40 pmFCO - CHS

2 stops32h 49mFinnair

Deal found 12/27

$471

Thu 5/1411:05 amFCO - CHS

2 stops18h 23mAmerican Airlines

Deal found 12/27

$475

Thu 5/146:55 amFCO - CHS

2 stops20h 19mBritish Airways

Deal found 12/26

$476

Find flight deals from Rome to South Carolina

Round-trip from	$528 (Trip.com)
One-way from	$282 (Kiwi.com)

From Rome (ROM) to South Carolina

Search Deals

One-way flight from Rome (ROM) to South Carolina

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Rome to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Fri 2/13

1:10 pm-9:18 pm

1 stop14h 08m

Charlotte Douglas

Thu 2/26

8:20 pm-7:10 pm

1 stop16h 50m

$646

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Sat 4/4

2:05 pm-3:05 pm

1 stop31h 00m

Charlotte Douglas

Mon 4/13

5:50 pm-8:15 pm

1 stop20h 25m

$650

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Tue 2/10

10:40 am-8:40 am

2 stops28h 00m

Charlotte Douglas

Tue 2/17

11:05 pm-9:55 pm

1 stop16h 50m

$658

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Fri 2/13

1:10 pm-10:39 am

1 stop27h 29m

Charlotte Douglas

Thu 2/26

11:00 pm-7:10 pm

1 stop14h 10m

$663

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Fri 2/13

1:10 pm-9:18 pm

1 stop14h 08m

Charlotte Douglas

Thu 2/26

8:02 pm-7:10 pm

2 stops17h 08m

$664

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Wed 3/25

1:10 pm-11:25 pm

1 stop15h 15m

Charlotte Douglas

Mon 4/13

5:50 pm-12:55 pm

1 stop13h 05m

$665

RomeCharlotte

FCO - CLT

FCOCLT

Rome Fiumicino

Thu 1/29

11:10 am-4:05 pm

1 stop34h 55m

Charlotte Douglas

Mon 2/2

6:08 pm-2:55 pm

2 stops14h 47m

$666

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Fri 2/27

7:05 am-6:19 pm

2 stops17h 14m

Charleston

Mon 3/2

5:05 pm-7:45 am

1 stop32h 40m

$735

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Mon 2/9

7:05 am-2:48 pm

2 stops37h 43m

Charleston

Mon 2/16

2:48 pm-2:00 pm

2 stops17h 12m

$735

RomeCharleston

FCO - CHS

FCOCHS

Rome Fiumicino

Mon 2/9

11:00 am-7:04 pm

1 stop14h 04m

Charleston

Mon 2/16

2:48 pm-1:25 pm

2 stops16h 37m

$755

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 36 results

Best time to book a flight from Rome to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Rome with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to South Carolina

No data available for this route at this time. Please check back soon.

Related info for your journey

How long is the flight from Rome to South Carolina?
Airlines like American Airlines and United Airlines fly from Rome to South Carolina in about 17h 14m. The time it takes to get you to your destination can typically vary by up to 10h 15m. There are 4855 mi between Rome and South Carolina. This flight may include one or multiple stops.
What are the most popular routes from Rome to South Carolina?
When deciding which route to take from Rome to South Carolina consider Rome Fiumicino - Charlotte Douglas, Rome Fiumicino - Greenville or Rome Fiumicino - Charleston as they are the most popular.
Can I find deals for flights from Rome to South Carolina that include hotel bookings?
Yes. In addition to deals on Rome to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Rome to South Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to South Carolina.
Can I find deals for business class flights from Rome to South Carolina?
Yes. Cheapflights offers flight deals from Rome to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Rome to South Carolina

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Leonardo da Vinci/Fiumicino to Philadelphia flights

Leonardo da Vinci/Fiumicino to Dallas/Fort Worth flights

Ciampino to O'Hare Intl flights

Ciampino to San Francisco flights

Leonardo da Vinci/Fiumicino to Atlanta flights

Leonardo da Vinci/Fiumicino to Reagan-National flights

Leonardo da Vinci/Fiumicino to Ontario flights

Leonardo da Vinci/Fiumicino to Baltimore flights

Leonardo da Vinci/Fiumicino to Midway flights

Leonardo da Vinci/Fiumicino to Orlando flights

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Leonardo da Vinci/Fiumicino to Santa Ana flights

Leonardo da Vinci/Fiumicino to Denver flights

Leonardo da Vinci/Fiumicino to Detroit flights

Ciampino to Atlanta flights

Ciampino to Dallas/Fort Worth flights

Leonardo da Vinci/Fiumicino to George Bush Intcntl flights

Leonardo da Vinci/Fiumicino to St. Louis flights

Leonardo da Vinci/Fiumicino to Tampa flights

Leonardo da Vinci/Fiumicino to Seattle flights

Leonardo da Vinci/Fiumicino to Minneapolis flights

Leonardo da Vinci/Fiumicino to San Jose flights

Leonardo da Vinci/Fiumicino to San Diego flights

Leonardo da Vinci/Fiumicino to New Orleans flights

Leonardo da Vinci/Fiumicino to Charlotte flights

Leonardo da Vinci/Fiumicino to Raleigh flights

Ciampino to Denver flights

Ciampino to Baltimore flights

Leonardo da Vinci/Fiumicino to Sky Harbor Intl flights

Leonardo da Vinci/Fiumicino to Anchorage flights

Complete your trip

South Carolina car rentals

Charleston Airport car rentals

Myrtle Beach Intl Airport car rentals

Greenville Airport car rentals

Columbia Metropolitan Airport car rentals

Hilton Head Island Airport car rentals

Florence Airport car rentals

Myrtle Beach car rentals

Charleston car rentals

Columbia car rentals

Greenville car rentals

Florence car rentals

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$282+ Cheap flights from Rome (ROM) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Rome to South Carolina with Cheapflights

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Cheap flight deals from Rome to South Carolina

Cheapest flights from Rome to South CarolinaExplore the most affordable flight options available from Rome to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Explore the most affordable flight options available from Rome to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Find flight deals from Rome to South Carolina

Keep the following information in mind while searching for Rome to South Carolina flight deals. Data was last updated December 28, 2025.

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Rome to South Carolina that are best for you.

Best time to book a flight from Rome to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Rome with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Rome to South Carolina

Related info for your journey

Find useful and relevant information for your journey from Rome to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Rome to South Carolina?

What are the most popular routes from Rome to South Carolina?

Can I find deals for flights from Rome to South Carolina that include hotel bookings?

How can I find direct flights from Rome to South Carolina?

Can I find deals for business class flights from Rome to South Carolina?

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Alternative routes for Rome to South Carolina

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Cheapest flights from Rome to South Carolina
Explore the most affordable flight options available from Rome to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.